DK2523968T3 - Cykliske peptider til regulering af vektorielle ionkanaler - Google Patents

Cykliske peptider til regulering af vektorielle ionkanaler

Info

Publication number
DK2523968T3
DK2523968T3 DK11705798.4T DK11705798T DK2523968T3 DK 2523968 T3 DK2523968 T3 DK 2523968T3 DK 11705798 T DK11705798 T DK 11705798T DK 2523968 T3 DK2523968 T3 DK 2523968T3
Authority
DK
Denmark
Prior art keywords
regulating
ion channels
cyclic peptides
vectorial ion
vectorial
Prior art date
Application number
DK11705798.4T
Other languages
Danish (da)
English (en)
Inventor
Bernhard Fischer
Rudolf Lucas
Susan Tzotzos
Original Assignee
Apeptico Forschung & Entwicklung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apeptico Forschung & Entwicklung Gmbh filed Critical Apeptico Forschung & Entwicklung Gmbh
Application granted granted Critical
Publication of DK2523968T3 publication Critical patent/DK2523968T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK11705798.4T 2010-01-14 2011-01-12 Cykliske peptider til regulering af vektorielle ionkanaler DK2523968T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0004110A AT509267A1 (de) 2010-01-14 2010-01-14 Organische verbindungen zur regulierung von vektoriellen ionenkanälen
PCT/AT2011/000014 WO2011085423A1 (de) 2010-01-14 2011-01-12 Zyklische peptide zur regulierung von vektoriellen ionenkanälen

Publications (1)

Publication Number Publication Date
DK2523968T3 true DK2523968T3 (da) 2014-11-03

Family

ID=43970939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11705798.4T DK2523968T3 (da) 2010-01-14 2011-01-12 Cykliske peptider til regulering af vektorielle ionkanaler

Country Status (16)

Country Link
US (1) US8754049B2 (https=)
EP (1) EP2523968B1 (https=)
JP (1) JP5771220B2 (https=)
KR (1) KR101865420B1 (https=)
CN (1) CN102770442B (https=)
AT (1) AT509267A1 (https=)
AU (1) AU2011206907B2 (https=)
BR (1) BR112012017093A2 (https=)
CA (1) CA2785185C (https=)
DK (1) DK2523968T3 (https=)
ES (1) ES2525381T3 (https=)
IL (1) IL220924B (https=)
NZ (1) NZ600818A (https=)
PL (1) PL2523968T3 (https=)
RU (1) RU2538597C2 (https=)
WO (1) WO2011085423A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
KR102217476B1 (ko) * 2013-04-23 2021-02-19 아펩티코 포어슝 운트 엔트빅크룽 게엠베하 식 x₁-gqretpegaeakpwy-x₂의 고리 펩티드를 함유하는 동결건조물
US20160143266A1 (en) * 2013-04-23 2016-05-26 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical Composition Comprising a Cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
CA2939635A1 (en) * 2014-03-04 2015-09-11 Apeptico Forschung Und Entwicklung Gmbh Attenuation of intrapulmonary inflammation
IL258067B (en) * 2015-09-14 2022-08-01 Apeptico Forschung & Entwicklung Gmbh Circular protein for the treatment of pha type 1b

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968753A (en) * 1994-06-14 1999-10-19 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
EP1264599B1 (en) 1998-08-14 2007-09-26 Rudolf Lucas TNF-derived peptides for use in treating oedema
FR2839514A1 (fr) * 2002-05-07 2003-11-14 Centre Nat Rech Scient Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens
CA2575513C (en) * 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
CN101007791A (zh) * 2007-01-12 2007-08-01 东华大学 一种氨基酸联苯化合物
CN101003520A (zh) * 2007-01-12 2007-07-25 陈志龙 一种缬氨酸丁酰联苯化合物
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
AT506151B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Fusionsprotein
AT506150B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Zyklisches und cystein-freies peptid
CN101298432B (zh) * 2008-05-30 2010-12-22 广州市星业科技发展有限公司 L-吡咯烷酮羧酸钠的制备方法
EP2296685B1 (en) * 2008-06-04 2015-09-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
PL2397151T3 (pl) * 2010-06-21 2015-10-30 Apeptico Forschung & Entwicklung Gmbh Leczenie powikłań naczyniowych cukrzycy

Also Published As

Publication number Publication date
AT509267A1 (de) 2011-07-15
RU2538597C2 (ru) 2015-01-10
KR20120134100A (ko) 2012-12-11
KR101865420B1 (ko) 2018-07-13
IL220924B (en) 2018-04-30
AU2011206907B2 (en) 2016-06-02
PL2523968T3 (pl) 2015-03-31
NZ600818A (en) 2014-02-28
ES2525381T3 (es) 2014-12-23
JP2013517224A (ja) 2013-05-16
JP5771220B2 (ja) 2015-08-26
AU2011206907A1 (en) 2012-06-21
HK1174341A1 (en) 2013-06-07
CA2785185C (en) 2019-02-19
EP2523968B1 (de) 2014-09-10
US8754049B2 (en) 2014-06-17
CA2785185A1 (en) 2011-07-21
CN102770442A (zh) 2012-11-07
WO2011085423A1 (de) 2011-07-21
RU2012134322A (ru) 2014-02-20
EP2523968A1 (de) 2012-11-21
US20130072444A1 (en) 2013-03-21
BR112012017093A2 (pt) 2016-11-29
CN102770442B (zh) 2015-09-23

Similar Documents

Publication Publication Date Title
DK2580156T4 (da) Fremgangsmåde til lagring af hydrogen
DK2813512T3 (da) Fremgangsmåde til cyklisering af en peptidforbindelse
DK3103469T3 (en) Indgivelse af terapeutiske midler til centralnervesystemet
DK2906696T3 (da) Fremgangsmåder til modulering af c9orf72-ekspression
DK2652527T3 (da) Seismisk registrering ved anvendelse af seismiske smalbåndskilder
DK3723369T3 (da) Indretning til kortlægning af intraprædikationsmodus
DK2893001T3 (da) Fremgangsmåde til dyrkning af mesenkymale stamceller
DK2758172T3 (da) System til udførelse af reaktioner
DK2596632T3 (da) Tilvejebringelse af sekvensdatasæt til streaming af videodata
DK2909027T3 (da) Stak af indkapslingsbarrierer
DK2922574T3 (da) Kemisk spaltbar gruppe
DK2776224T3 (da) Fremgangsmåde til formaling af poly(aryletherketoner)
DK2649101T3 (da) Fremgangsmåde til fremstilling af en tværbundet gel
DK2569129T3 (da) Fremgangsmåde til styring af en automatiseret arbejdscelle
DK2982699T3 (da) Fremgangsmåde til fremstilling af vinylpolymerdispersioner
DK3322183T3 (da) Fremgangsmåde til intraforudsigelse af video
DK2595948T3 (da) Fremgangsmåde til fremstilling af ingenol-3-angelat
DK3396980T3 (da) Binaural kompressor til opnåelse af retningsanvisninger
EP2891072A4 (en) OPEN ARCHITECTURE FOR SELF-ORGANIZING NETWORKS
DK2550620T3 (da) System til distribution af betroet indhold
DK2506603T3 (da) Høreapparatsystem med et retningsbestemt mikrofonsystem og fremgangsmåde til drift af et sådant høreapparatsystem med et retningsbestemt mikrofonsystem
DK2751924T3 (da) Fremgangsmåde til regulering af et generatorsæt
DK2986308T3 (en) Angiotensin ii i kombination til behandlingen af hypotension
DK2567019T3 (da) Fremgangsmåde til coating af tekstiler
DK2732707T3 (da) Fremgangsmåde til fremstilling af en sammensætning indeholdende caseinomacropeptid