KR101865420B1 - 벡터적 이온 채널의 조절을 위한 유기화합물 - Google Patents

벡터적 이온 채널의 조절을 위한 유기화합물 Download PDF

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KR101865420B1
KR101865420B1 KR1020127018445A KR20127018445A KR101865420B1 KR 101865420 B1 KR101865420 B1 KR 101865420B1 KR 1020127018445 A KR1020127018445 A KR 1020127018445A KR 20127018445 A KR20127018445 A KR 20127018445A KR 101865420 B1 KR101865420 B1 KR 101865420B1
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amino acid
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KR20120134100A (ko
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베른하드 피셔
루돌프 루카스
수잔 조조스
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아펩티코 포어슝 운트 엔트빅크룽 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127018445A 2010-01-14 2011-01-12 벡터적 이온 채널의 조절을 위한 유기화합물 Active KR101865420B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0004110A AT509267A1 (de) 2010-01-14 2010-01-14 Organische verbindungen zur regulierung von vektoriellen ionenkanälen
ATA41/2010 2010-01-14
PCT/AT2011/000014 WO2011085423A1 (de) 2010-01-14 2011-01-12 Zyklische peptide zur regulierung von vektoriellen ionenkanälen

Publications (2)

Publication Number Publication Date
KR20120134100A KR20120134100A (ko) 2012-12-11
KR101865420B1 true KR101865420B1 (ko) 2018-07-13

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KR1020127018445A Active KR101865420B1 (ko) 2010-01-14 2011-01-12 벡터적 이온 채널의 조절을 위한 유기화합물

Country Status (16)

Country Link
US (1) US8754049B2 (https=)
EP (1) EP2523968B1 (https=)
JP (1) JP5771220B2 (https=)
KR (1) KR101865420B1 (https=)
CN (1) CN102770442B (https=)
AT (1) AT509267A1 (https=)
AU (1) AU2011206907B2 (https=)
BR (1) BR112012017093A2 (https=)
CA (1) CA2785185C (https=)
DK (1) DK2523968T3 (https=)
ES (1) ES2525381T3 (https=)
IL (1) IL220924B (https=)
NZ (1) NZ600818A (https=)
PL (1) PL2523968T3 (https=)
RU (1) RU2538597C2 (https=)
WO (1) WO2011085423A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
KR102217476B1 (ko) * 2013-04-23 2021-02-19 아펩티코 포어슝 운트 엔트빅크룽 게엠베하 식 ｘ₁－ｇｑｒｅｔｐｅｇａｅａｋｐｗｙ－ｘ₂의 고리 펩티드를 함유하는 동결건조물
US20160143266A1 (en) * 2013-04-23 2016-05-26 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical Composition Comprising a Cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
CA2939635A1 (en) * 2014-03-04 2015-09-11 Apeptico Forschung Und Entwicklung Gmbh Attenuation of intrapulmonary inflammation
IL258067B (en) * 2015-09-14 2022-08-01 Apeptico Forschung & Entwicklung Gmbh Circular protein for the treatment of pha type 1b

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073909A1 (de) * 2007-12-12 2009-06-18 Apeptico Forschung Und Entwicklung Gmbh Zyklisches, cystein-freies protein

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Publication number Priority date Publication date Assignee Title
US5968753A (en) * 1994-06-14 1999-10-19 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
EP1264599B1 (en) 1998-08-14 2007-09-26 Rudolf Lucas TNF-derived peptides for use in treating oedema
FR2839514A1 (fr) * 2002-05-07 2003-11-14 Centre Nat Rech Scient Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens
CA2575513C (en) * 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
CN101007791A (zh) * 2007-01-12 2007-08-01 东华大学 一种氨基酸联苯化合物
CN101003520A (zh) * 2007-01-12 2007-07-25 陈志龙 一种缬氨酸丁酰联苯化合物
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
AT506151B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Fusionsprotein
CN101298432B (zh) * 2008-05-30 2010-12-22 广州市星业科技发展有限公司 L-吡咯烷酮羧酸钠的制备方法
EP2296685B1 (en) * 2008-06-04 2015-09-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
PL2397151T3 (pl) * 2010-06-21 2015-10-30 Apeptico Forschung & Entwicklung Gmbh Leczenie powikłań naczyniowych cukrzycy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073909A1 (de) * 2007-12-12 2009-06-18 Apeptico Forschung Und Entwicklung Gmbh Zyklisches, cystein-freies protein

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
국제공개공보 WO2009/073909(2009.06.18.) 1부. *

Also Published As

Publication number Publication date
AT509267A1 (de) 2011-07-15
DK2523968T3 (da) 2014-11-03
RU2538597C2 (ru) 2015-01-10
KR20120134100A (ko) 2012-12-11
IL220924B (en) 2018-04-30
AU2011206907B2 (en) 2016-06-02
PL2523968T3 (pl) 2015-03-31
NZ600818A (en) 2014-02-28
ES2525381T3 (es) 2014-12-23
JP2013517224A (ja) 2013-05-16
JP5771220B2 (ja) 2015-08-26
AU2011206907A1 (en) 2012-06-21
HK1174341A1 (en) 2013-06-07
CA2785185C (en) 2019-02-19
EP2523968B1 (de) 2014-09-10
US8754049B2 (en) 2014-06-17
CA2785185A1 (en) 2011-07-21
CN102770442A (zh) 2012-11-07
WO2011085423A1 (de) 2011-07-21
RU2012134322A (ru) 2014-02-20
EP2523968A1 (de) 2012-11-21
US20130072444A1 (en) 2013-03-21
BR112012017093A2 (pt) 2016-11-29
CN102770442B (zh) 2015-09-23

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