DK2516406T3 - Mglu2-agonister - Google Patents
Mglu2-agonisterInfo
- Publication number
- DK2516406T3 DK2516406T3 DK10798419.7T DK10798419T DK2516406T3 DK 2516406 T3 DK2516406 T3 DK 2516406T3 DK 10798419 T DK10798419 T DK 10798419T DK 2516406 T3 DK2516406 T3 DK 2516406T3
- Authority
- DK
- Denmark
- Prior art keywords
- mglu2 agonists
- mglu2
- agonists
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09382290 | 2009-12-21 | ||
| US30523910P | 2010-02-17 | 2010-02-17 | |
| PCT/US2010/060371 WO2011084437A1 (en) | 2009-12-21 | 2010-12-15 | Mglu2 agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2516406T3 true DK2516406T3 (da) | 2013-10-14 |
Family
ID=42026702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10798419.7T DK2516406T3 (da) | 2009-12-21 | 2010-12-15 | Mglu2-agonister |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8318184B2 (da) |
| EP (1) | EP2516406B1 (da) |
| JP (1) | JP5779190B2 (da) |
| KR (1) | KR101395356B1 (da) |
| CN (1) | CN102695701B (da) |
| AR (1) | AR079343A1 (da) |
| AU (1) | AU2010340039B2 (da) |
| BR (1) | BR112012017188B1 (da) |
| CA (1) | CA2784667C (da) |
| CR (1) | CR20120322A (da) |
| CY (1) | CY1114880T1 (da) |
| DK (1) | DK2516406T3 (da) |
| DO (1) | DOP2012000173A (da) |
| EA (1) | EA020229B1 (da) |
| EC (1) | ECSP12011989A (da) |
| ES (1) | ES2435651T3 (da) |
| HK (1) | HK1171228A1 (da) |
| HN (1) | HN2012001160A (da) |
| HR (1) | HRP20131052T1 (da) |
| IL (1) | IL220011A (da) |
| JO (1) | JO2978B1 (da) |
| MA (1) | MA33824B1 (da) |
| MX (1) | MX2012007332A (da) |
| MY (1) | MY160618A (da) |
| NZ (1) | NZ600305A (da) |
| PE (1) | PE20121688A1 (da) |
| PL (1) | PL2516406T3 (da) |
| PT (1) | PT2516406E (da) |
| RS (1) | RS53063B (da) |
| SG (1) | SG181836A1 (da) |
| SI (1) | SI2516406T1 (da) |
| TN (1) | TN2012000281A1 (da) |
| TW (1) | TWI477490B (da) |
| UA (1) | UA107684C2 (da) |
| WO (1) | WO2011084437A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3533797B1 (en) | 2010-02-17 | 2023-12-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| JP5870111B2 (ja) * | 2010-11-18 | 2016-02-24 | イーライ リリー アンド カンパニー | ｍＧｌｕＲ２／３アンタゴニストとしての４−置換−３−ベンジルオキシ−ビシクロ［３．１．０］ヘキサン化合物 |
| TWI520935B (zh) * | 2010-11-18 | 2016-02-11 | 美國禮來大藥廠 | 作為ｍＧｌｕＲ２／３拮抗劑之４－經取代－３－苯基磺醯基甲基－雙環［３.１.０］己烷化合物 |
| HUE030171T2 (en) * | 2011-06-17 | 2017-05-29 | Lilly Co Eli | Bicyclo (3.1.0) hexane-2,6-dicarboxylic acid derivatives such as mGlu2 receptor agonists |
| AR089718A1 (es) | 2012-02-01 | 2014-09-10 | Lilly Co Eli | AGONISTAS DE mGlu2/3 |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
| KR20200036063A (ko) | 2014-01-21 | 2020-04-06 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| JP6629740B2 (ja) * | 2014-01-21 | 2020-01-15 | ヤンセン ファーマシューティカ エヌ．ベー． | 代謝型グルタミン酸作動性受容体サブタイプ２の正のアロステリック調節因子またはオルトステリックアゴニストを含む組み合わせ、およびそれらの使用 |
| DK3277270T3 (da) | 2015-04-01 | 2021-12-06 | Akebia Therapeutics Inc | Sammensætninger og fremgangsmåder til behandling af anæmi |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5576323A (en) | 1993-12-03 | 1996-11-19 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5688826A (en) * | 1995-11-16 | 1997-11-18 | Eli Lilly And Company | Excitatory amino acid derivatives |
| GB9605429D0 (en) * | 1995-11-16 | 1996-05-15 | Lilly Co Eli | Excitatory amino acid receptor antagonists |
| ZA983930B (en) | 1997-05-14 | 1999-11-08 | Lilly Co Eli | Excitatory amino acid receptor modulators. |
| WO2002055485A1 (en) * | 2001-01-11 | 2002-07-18 | Eli Lilly And Company | Prodrugs of excitatory amino acids |
| CN1267407C (zh) * | 2001-01-11 | 2006-08-02 | 伊莱利利公司 | 兴奋性氨基酸前体药物 |
| EP1370519A1 (en) * | 2001-02-22 | 2003-12-17 | Eli Lilly And Company | Synthetic excitatory amino acids |
| AU2003232146B2 (en) | 2002-06-11 | 2009-06-18 | Eli Lilly And Company | Prodrugs of excitatory amino acids |
| US7381746B2 (en) * | 2003-06-26 | 2008-06-03 | Taisho Pharmaceutical Co., Ltd. | 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative |
| JP5870111B2 (ja) * | 2010-11-18 | 2016-02-24 | イーライ リリー アンド カンパニー | ｍＧｌｕＲ２／３アンタゴニストとしての４−置換−３−ベンジルオキシ−ビシクロ［３．１．０］ヘキサン化合物 |
| TWI520935B (zh) * | 2010-11-18 | 2016-02-11 | 美國禮來大藥廠 | 作為ｍＧｌｕＲ２／３拮抗劑之４－經取代－３－苯基磺醯基甲基－雙環［３.１.０］己烷化合物 |
-
2010
- 2010-12-09 JO JO2010439A patent/JO2978B1/en active
- 2010-12-09 AR ARP100104553A patent/AR079343A1/es active IP Right Grant
- 2010-12-10 TW TW099143362A patent/TWI477490B/zh active
- 2010-12-15 MX MX2012007332A patent/MX2012007332A/es active IP Right Grant
- 2010-12-15 CN CN201080058183.2A patent/CN102695701B/zh active Active
- 2010-12-15 ES ES10798419T patent/ES2435651T3/es active Active
- 2010-12-15 DK DK10798419.7T patent/DK2516406T3/da active
- 2010-12-15 US US12/968,352 patent/US8318184B2/en active Active
- 2010-12-15 RS RS20130530A patent/RS53063B/en unknown
- 2010-12-15 KR KR1020127015935A patent/KR101395356B1/ko active IP Right Grant
- 2010-12-15 JP JP2012544727A patent/JP5779190B2/ja active Active
- 2010-12-15 SG SG2012045563A patent/SG181836A1/en unknown
- 2010-12-15 PE PE2012000856A patent/PE20121688A1/es active IP Right Grant
- 2010-12-15 CA CA2784667A patent/CA2784667C/en active Active
- 2010-12-15 BR BR112012017188-7A patent/BR112012017188B1/pt active IP Right Grant
- 2010-12-15 SI SI201030387T patent/SI2516406T1/sl unknown
- 2010-12-15 PT PT107984197T patent/PT2516406E/pt unknown
- 2010-12-15 PL PL10798419T patent/PL2516406T3/pl unknown
- 2010-12-15 AU AU2010340039A patent/AU2010340039B2/en active Active
- 2010-12-15 WO PCT/US2010/060371 patent/WO2011084437A1/en active Application Filing
- 2010-12-15 UA UAA201206909A patent/UA107684C2/ru unknown
- 2010-12-15 EP EP10798419.7A patent/EP2516406B1/en active Active
- 2010-12-15 NZ NZ600305A patent/NZ600305A/en unknown
- 2010-12-15 EA EA201290558A patent/EA020229B1/ru not_active IP Right Cessation
- 2010-12-15 MY MYPI2012002794A patent/MY160618A/en unknown
-
2012
- 2012-05-24 IL IL220011A patent/IL220011A/en active IP Right Grant
- 2012-05-30 HN HN2012001160A patent/HN2012001160A/es unknown
- 2012-06-01 TN TNP2012000281A patent/TN2012000281A1/en unknown
- 2012-06-13 CR CR20120322A patent/CR20120322A/es unknown
- 2012-06-14 MA MA34967A patent/MA33824B1/fr unknown
- 2012-06-19 DO DO2012000173A patent/DOP2012000173A/es unknown
- 2012-06-20 EC ECSP12011989 patent/ECSP12011989A/es unknown
- 2012-11-23 HK HK12112042.9A patent/HK1171228A1/xx unknown
-
2013
- 2013-11-06 HR HRP20131052AT patent/HRP20131052T1/hr unknown
- 2013-11-14 CY CY20131101012T patent/CY1114880T1/el unknown
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