DK24088D0 - Fremgangsmaade og mellemprodukter til fremstilling af thiazolobenzimidazoler - Google Patents
Fremgangsmaade og mellemprodukter til fremstilling af thiazolobenzimidazolerInfo
- Publication number
- DK24088D0 DK24088D0 DK024088A DK24088A DK24088D0 DK 24088 D0 DK24088 D0 DK 24088D0 DK 024088 A DK024088 A DK 024088A DK 24088 A DK24088 A DK 24088A DK 24088 D0 DK24088 D0 DK 24088D0
- Authority
- DK
- Denmark
- Prior art keywords
- acid
- formula
- chem
- salt
- water
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- IHCQWURUZRYCIU-UHFFFAOYSA-N [1,3]thiazolo[3,2-a]benzimidazole Chemical compound C1=CC=C2N3C=CSC3=NC2=C1 IHCQWURUZRYCIU-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8701228 | 1987-01-21 | ||
| GB878701228A GB8701228D0 (en) | 1987-01-21 | 1987-01-21 | Thiazolobenzimidazoles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK24088D0 true DK24088D0 (da) | 1988-01-20 |
| DK24088A DK24088A (da) | 1988-07-06 |
| DK169819B1 DK169819B1 (da) | 1995-03-06 |
Family
ID=10610964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK024088A DK169819B1 (da) | 1987-01-21 | 1988-01-20 | Fremgangsmåde til fremstilling af 3-phenylthiazolo(3,2-a)benzimidazolderivater eller et salt deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4812574A (da) |
| EP (1) | EP0276133B1 (da) |
| JP (1) | JP2555397B2 (da) |
| KR (1) | KR960004536B1 (da) |
| AT (1) | ATE86257T1 (da) |
| AU (1) | AU602045B2 (da) |
| CA (1) | CA1327042C (da) |
| DE (1) | DE3878700T2 (da) |
| DK (1) | DK169819B1 (da) |
| ES (1) | ES2045098T3 (da) |
| GB (2) | GB8701228D0 (da) |
| HU (1) | HU201081B (da) |
| IE (1) | IE61348B1 (da) |
| IL (1) | IL85135A (da) |
| PT (1) | PT86567B (da) |
| ZA (1) | ZA88378B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1243362B (it) * | 1990-07-25 | 1994-06-10 | Pietro Monforte | Sintesi di attivita' anti-hiv di 1h, 3h-tiazolo 3,4-a benzimidazoli 1-sostituiti |
| WO2010077295A1 (en) * | 2008-12-09 | 2010-07-08 | King Faisal Specialist Hospital & Research Centre | Substituted tricyclic heterocycles and uses to treat tumors and proliferative disorders |
| CN111116613B (zh) * | 2019-12-13 | 2021-04-23 | 湘潭大学 | 一种多取代苯并咪唑并噻唑及衍生物及其合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1380507A (fr) * | 1963-08-28 | 1964-12-04 | Emballages Transparents Soc D | Procédé et dispositif pour la fabrication d'emballages se présentant sous forme de sachets multiples accolés ou superposés |
| US4214089A (en) * | 1978-07-18 | 1980-07-22 | American Home Products Corporation | Thiazolo[3,2-a]benzimidazoles, imidazo [2,1-b]thiazoles, and related compounds as antineoplastic agents, and enhancers of the immune response |
| US4361574A (en) * | 1981-10-02 | 1982-11-30 | American Home Products Corporation | Inhibitors of mammalian collagenase |
| US4466957A (en) * | 1982-02-25 | 1984-08-21 | American Home Products Corporation | Vaccine adjuvants |
-
1987
- 1987-01-21 GB GB878701228A patent/GB8701228D0/en active Pending
- 1987-12-23 US US07/133,823 patent/US4812574A/en not_active Expired - Fee Related
-
1988
- 1988-01-19 AU AU10379/88A patent/AU602045B2/en not_active Ceased
- 1988-01-19 IL IL85135A patent/IL85135A/xx not_active IP Right Cessation
- 1988-01-19 PT PT86567A patent/PT86567B/pt not_active IP Right Cessation
- 1988-01-20 AT AT88300432T patent/ATE86257T1/de not_active IP Right Cessation
- 1988-01-20 DE DE8888300432T patent/DE3878700T2/de not_active Expired - Fee Related
- 1988-01-20 EP EP88300432A patent/EP0276133B1/en not_active Expired - Lifetime
- 1988-01-20 ZA ZA88378A patent/ZA88378B/xx unknown
- 1988-01-20 ES ES88300432T patent/ES2045098T3/es not_active Expired - Lifetime
- 1988-01-20 GB GB8801219A patent/GB2200116B/en not_active Expired - Fee Related
- 1988-01-20 JP JP63010569A patent/JP2555397B2/ja not_active Expired - Lifetime
- 1988-01-20 DK DK024088A patent/DK169819B1/da not_active IP Right Cessation
- 1988-01-20 IE IE14388A patent/IE61348B1/en not_active IP Right Cessation
- 1988-01-20 HU HU88216A patent/HU201081B/hu not_active IP Right Cessation
- 1988-01-20 CA CA000556943A patent/CA1327042C/en not_active Expired - Fee Related
- 1988-01-21 KR KR1019880000433A patent/KR960004536B1/ko not_active Expired - Fee Related
-
1989
- 1989-01-10 US US07/295,410 patent/US4889936A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0276133B1 (en) | 1993-03-03 |
| ATE86257T1 (de) | 1993-03-15 |
| DE3878700T2 (de) | 1993-06-09 |
| EP0276133A3 (en) | 1990-03-21 |
| GB8701228D0 (en) | 1987-02-25 |
| ES2045098T3 (es) | 1994-01-16 |
| JP2555397B2 (ja) | 1996-11-20 |
| DK169819B1 (da) | 1995-03-06 |
| PT86567B (pt) | 1991-12-31 |
| HU201081B (en) | 1990-09-28 |
| IE61348B1 (en) | 1994-11-02 |
| IL85135A0 (en) | 1988-06-30 |
| DE3878700D1 (de) | 1993-04-08 |
| PT86567A (en) | 1988-02-01 |
| CA1327042C (en) | 1994-02-15 |
| IE880143L (en) | 1988-07-21 |
| JPS63198689A (ja) | 1988-08-17 |
| US4889936A (en) | 1989-12-26 |
| AU602045B2 (en) | 1990-09-27 |
| GB2200116B (en) | 1991-06-12 |
| EP0276133A2 (en) | 1988-07-27 |
| KR880009031A (ko) | 1988-09-13 |
| AU1037988A (en) | 1988-07-28 |
| ZA88378B (en) | 1989-09-27 |
| HUT50835A (en) | 1990-03-28 |
| DK24088A (da) | 1988-07-06 |
| US4812574A (en) | 1989-03-14 |
| IL85135A (en) | 1992-07-15 |
| GB2200116A (en) | 1988-07-27 |
| GB8801219D0 (en) | 1988-02-17 |
| KR960004536B1 (ko) | 1996-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |