DK2389116T3 - Biopsi-understøtning til at orientere vævsprøver til sektionering i en mikrotom - Google Patents
Biopsi-understøtning til at orientere vævsprøver til sektionering i en mikrotom Download PDFInfo
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- DK2389116T3 DK2389116T3 DK10733886.5T DK10733886T DK2389116T3 DK 2389116 T3 DK2389116 T3 DK 2389116T3 DK 10733886 T DK10733886 T DK 10733886T DK 2389116 T3 DK2389116 T3 DK 2389116T3
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- Prior art keywords
- tissue
- cassette
- tissue sample
- microtome
- samples
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Links
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Sampling And Sample Adjustment (AREA)
Claims (14)
1. Histologisk indretning til understøtning af vævsprøve til orientering og fastholdelse af vævsprøver under behandling, indlejring og sektionering i en mikrotom, hvilken indretning omfatter en vævskassette, hvilken vævskassette indbefatter en perforeret bundvæg og mindst en perforeret sidevæg til at definere et vævsprøve-modtagelsesrum, hvilken kassette er dannet af materiale, som med succes kan snittes i en mikrotom og som er resistent over for nedbrydning fra opløsningsmidler og kemikalier, der anvendes til at fiksere, behandle og farve væv, hvilken vævskassette indbefatter første og anden forlængede kanaler (130a) til at modtage mindst en vævsprøve (100), hvilken første og anden kanal (130a) er adskilt fra hinanden ved hjælp af en struktur til adskillelse, hvilken adskillelsesstruktur er forbundet med og strækker sig opad fra bundvæggen og indbefatter et forankringselement, der indbefatter en overflade, som vender mod bundvæggen for at forankre adskillelsesstrukturen i et indlejringsmateriale under en fremgangsmåde til sektionering i en mikrotom, og en struktur til at forspænde en vævsprøve, der er konfigureret til at strække sig ind i den første og anden kanal (103a) for at tilbageholde vævsprøven eller -prøverne mod bundvæggen under bearbejdning og indlejring, hvilken vævsprøveforspændingsstruktur yderligere er i stand til at opnå vellykket sektionering i mikrotomen, kendetegnet ved, at indretningen omfatter yderligere fingre (140, 142) på modsatte sider af den første og anden kanal (130a) for at holde vævsprøven eller -prøverne i en ønsket orientering.
2. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor forspændingsstrukturen yderligere omfatter et elastisk cellulært materiale, der er konfigureret til at gå i indgreb med vævsprøven og holde vævsprøven fladt mod en referenceflade, hvilket elastiske cellulære materiale er porøst for at tillade infiltration af opløsningsmidlerne og kemikalier, der er anvendt til at fiksere, behandle og farve væv og indlejringsmateriale, der anvendes til at indlejre vævet, mens vævsprøven tilbageholdes af det fjedrende cellulære materiale.
3. Histologisk indretning til understøtning af vævsprøve ifølge krav 2, hvor det fjedrende cellulære materiale yderligere omfatter et skummateriale med åbne celler.
4. Histologisk indretning til understøtning af vævsprøve ifølge krav 3, hvor skummaterialet med åbne celler yderligere omfatter mindst en af en polyether eller en polyurethan.
5. Histologisk indretning til understøtning af vævsprøve ifølge krav 3, hvor det åbne celleskum er et fuldt retikuleret skum.
6. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor kassetten er dannet af en polymer.
7. Histologisk indretning til understøtning af vævsprøve ifølge krav 6, hvor polymeren er en fluoreret polymer.
8. Histologisk indretning til understøtning af vævsprøve ifølge krav 6, hvor polymeren er en fluorpolymer.
9. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor kassetten indbefatter et låg, og forspændingsstrukturen yderligere omfatter flere adskilte flige (105), der er forbundet med og strækker sig nedad fra låget til den første og anden kanal (130a).
10. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor adskillelsesstrukturen er perforeret.
11. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor adskillelsesstrukturen er konfigureret til at tillade vævsprøven at strække sig fra den første kanal til den anden kanal.
12. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, der yderligere omfatter en ramme, hvor vævskassetten fastholdes løsbart på rammen, hvilken vævskassette fortrinsvis er udformet til at være løsbart koblet til rammen, og rammen er yderligere er konfigureret til at være løsbart fastgjort inden i en mikrotompatron.
13. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor fingrene (140, 142) er forspændt udad væk fra hinanden.
14. Histologisk indretning til understøtning af vævsprøve ifølge krav 1, hvor fingrene (140, 142) er dannet på en ensrettet måde med modhager.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14644409P | 2009-01-22 | 2009-01-22 | |
US23891309P | 2009-09-01 | 2009-09-01 | |
PCT/US2010/021773 WO2010085626A1 (en) | 2009-01-22 | 2010-01-22 | Microtome sectionable biopsy support for orienting tissue samples |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2389116T3 true DK2389116T3 (da) | 2018-02-12 |
Family
ID=42337265
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10733886.5T DK2389116T3 (da) | 2009-01-22 | 2010-01-22 | Biopsi-understøtning til at orientere vævsprøver til sektionering i en mikrotom |
DK17200020T DK3300667T3 (da) | 2009-01-22 | 2010-01-22 | Biopsiunderstøtning der kan sektioneres i en mikrotom til orientering af vævsprøver |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17200020T DK3300667T3 (da) | 2009-01-22 | 2010-01-22 | Biopsiunderstøtning der kan sektioneres i en mikrotom til orientering af vævsprøver |
Country Status (10)
Country | Link |
---|---|
US (3) | US8329120B2 (da) |
EP (2) | EP2389116B1 (da) |
JP (2) | JP5706341B2 (da) |
CN (1) | CN102292030B (da) |
AU (1) | AU2010206709B2 (da) |
BR (1) | BRPI1006958B1 (da) |
CA (1) | CA2749135C (da) |
DK (2) | DK2389116T3 (da) |
ES (2) | ES2746196T3 (da) |
WO (1) | WO2010085626A1 (da) |
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EP2316010B1 (en) * | 2008-08-27 | 2022-03-16 | The University of Miami | Tissue cassette and method for preparing tissue samples |
WO2010103389A1 (de) | 2009-03-11 | 2010-09-16 | Sensovation Ag | Autofokusverfahren und autofokuseinrichtung |
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EP2616820A4 (en) | 2010-09-13 | 2014-04-09 | Primera Technology Inc | CARTRIDGES FOR HISTOLOGICAL OBJECTS |
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2010
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- 2010-01-22 DK DK17200020T patent/DK3300667T3/da active
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Publication number | Publication date |
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ES2746196T3 (es) | 2020-03-05 |
JP5788466B2 (ja) | 2015-09-30 |
BRPI1006958A2 (pt) | 2016-04-12 |
ES2652615T3 (es) | 2018-02-05 |
US20140205515A1 (en) | 2014-07-24 |
US8329120B2 (en) | 2012-12-11 |
CA2749135A1 (en) | 2010-07-29 |
BRPI1006958B1 (pt) | 2019-11-19 |
EP2389116A4 (en) | 2014-02-19 |
JP2012515926A (ja) | 2012-07-12 |
EP3300667A1 (en) | 2018-04-04 |
EP2389116A1 (en) | 2011-11-30 |
EP3300667B1 (en) | 2019-08-28 |
US20130078670A1 (en) | 2013-03-28 |
EP2389116B1 (en) | 2017-11-08 |
US20100184127A1 (en) | 2010-07-22 |
JP5706341B2 (ja) | 2015-04-22 |
US8796038B2 (en) | 2014-08-05 |
CN102292030A (zh) | 2011-12-21 |
CN102292030B (zh) | 2014-11-19 |
WO2010085626A1 (en) | 2010-07-29 |
JP2014041161A (ja) | 2014-03-06 |
AU2010206709B2 (en) | 2013-01-24 |
AU2010206709A1 (en) | 2011-07-28 |
DK3300667T3 (da) | 2019-12-02 |
CA2749135C (en) | 2017-04-18 |
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