DK2355822T3 - behandling af kognitive forstyrrelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzoe[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf - Google Patents

behandling af kognitive forstyrrelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzoe[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf

Info

Publication number
DK2355822T3
DK2355822T3 DK09756921.4T DK09756921T DK2355822T3 DK 2355822 T3 DK2355822 T3 DK 2355822T3 DK 09756921 T DK09756921 T DK 09756921T DK 2355822 T3 DK2355822 T3 DK 2355822T3
Authority
DK
Denmark
Prior art keywords
quinuclidin
carboxamide
thiophene
benzo
chloro
Prior art date
Application number
DK09756921.4T
Other languages
English (en)
Inventor
Gerhard Koenig
Richard Chesworth
Gideon Shapiro
Original Assignee
Envivo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41786120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2355822(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Envivo Pharmaceuticals Inc filed Critical Envivo Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2355822T3 publication Critical patent/DK2355822T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
DK09756921.4T 2008-11-19 2009-11-19 behandling af kognitive forstyrrelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzoe[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf DK2355822T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11610608P 2008-11-19 2008-11-19
PCT/US2009/065173 WO2010059844A1 (en) 2008-11-19 2009-11-19 Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof

Publications (1)

Publication Number Publication Date
DK2355822T3 true DK2355822T3 (da) 2013-01-28

Family

ID=41786120

Family Applications (3)

Application Number Title Priority Date Filing Date
DK09756921.4T DK2355822T3 (da) 2008-11-19 2009-11-19 behandling af kognitive forstyrrelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzoe[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf
DK12185913.6T DK2540297T3 (da) 2008-11-19 2009-11-19 Behandling af kognitive lidelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzo[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf
DK15151165.6T DK2889033T3 (da) 2008-11-19 2009-11-19 Behandling af negative symptomer på skizofreni med (R)-7-chlor-N-(quinuclidin-3-yl)benzo[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK12185913.6T DK2540297T3 (da) 2008-11-19 2009-11-19 Behandling af kognitive lidelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzo[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf
DK15151165.6T DK2889033T3 (da) 2008-11-19 2009-11-19 Behandling af negative symptomer på skizofreni med (R)-7-chlor-N-(quinuclidin-3-yl)benzo[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf

Country Status (35)

Country Link
US (6) US8642638B2 (da)
EP (4) EP2355822B1 (da)
JP (6) JP5272080B2 (da)
KR (3) KR20180011888A (da)
CN (3) CN105687190A (da)
AU (1) AU2009316557B2 (da)
BR (1) BRPI0922057A2 (da)
CA (3) CA2744278C (da)
CL (3) CL2011001178A1 (da)
CO (1) CO6400190A2 (da)
CR (1) CR20110267A (da)
CY (3) CY1113671T1 (da)
DK (3) DK2355822T3 (da)
EC (1) ECSP11011076A (da)
ES (3) ES2396300T3 (da)
HK (1) HK1158520A1 (da)
HR (3) HRP20130007T1 (da)
HU (2) HUE026815T2 (da)
IL (5) IL212921A (da)
LT (1) LT2889033T (da)
MX (1) MX2011005270A (da)
MY (2) MY173229A (da)
NZ (2) NZ593467A (da)
PE (1) PE20110711A1 (da)
PH (2) PH12014501629A1 (da)
PL (3) PL2540297T3 (da)
PT (3) PT2540297E (da)
RS (1) RS52583B (da)
RU (3) RU2532327C2 (da)
SG (1) SG10201504102QA (da)
SI (3) SI2540297T1 (da)
SM (2) SMT201300003B (da)
TR (1) TR201807944T4 (da)
WO (1) WO2010059844A1 (da)
ZA (1) ZA201104044B (da)

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SA111320455B1 (ar) 2010-05-17 2014-10-16 Envivo Pharmaceuticals Inc صورة بلورية من (R)-7- كلورو -N- (كينوكليدين -3- يل) بنزو[b] ثيوفين -2- كربوكساميد هيدروكلوريد أحادي الهيدرات
EP2640378A4 (en) * 2010-11-18 2014-05-21 Envivo Pharmaceuticals Inc INFLAMMATION TREATMENT WITH CERTAIN NICOTINIC ACID ALPHA-7 RECEPTOR AGONISTS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS
WO2012154710A1 (en) * 2011-05-09 2012-11-15 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with certain alpha-7 nicotinic acid receptor agonists in combination with nicotine
AU2012279298A1 (en) * 2011-07-01 2014-01-23 Envivo Pharmaceuticals, Inc. Methods of treatment of Limited Cognitive Impairment
EP3666272A1 (en) * 2012-05-08 2020-06-17 Forum Pharmaceuticals Inc. Use of encenicline in the treatment of cognitive impairment, alzheimer's disease, memory deficit
JP7170670B2 (ja) 2017-02-27 2022-11-14 ユニヴァーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイアー エデュケイション 抗精神病組成物及び治療方法
WO2019060298A1 (en) 2017-09-19 2019-03-28 Neuroenhancement Lab, LLC METHOD AND APPARATUS FOR NEURO-ACTIVATION
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11478603B2 (en) 2017-12-31 2022-10-25 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
WO2020056418A1 (en) 2018-09-14 2020-03-19 Neuroenhancement Lab, LLC System and method of improving sleep

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