DK2251353T3 - Homogene fremstillinger af IL-29 - Google Patents
Homogene fremstillinger af IL-29Info
- Publication number
- DK2251353T3 DK2251353T3 DK10173335.0T DK10173335T DK2251353T3 DK 2251353 T3 DK2251353 T3 DK 2251353T3 DK 10173335 T DK10173335 T DK 10173335T DK 2251353 T3 DK2251353 T3 DK 2251353T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acid
- seq
- cysteine
- acid residues
- correspond
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 1
- 125000000539 amino acid group Chemical group 0.000 abstract 4
- 235000018417 cysteine Nutrition 0.000 abstract 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 3
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 210000003494 hepatocyte Anatomy 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49319403P | 2003-08-07 | 2003-08-07 | |
| US55184104P | 2004-03-10 | 2004-03-10 | |
| US55914204P | 2004-04-02 | 2004-04-02 | |
| EP08150287A EP1927600A1 (en) | 2003-08-07 | 2004-08-09 | Homogeneous preparations of IL-28 and IL-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2251353T3 true DK2251353T3 (da) | 2013-06-03 |
Family
ID=34279787
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04809553T DK1668031T3 (da) | 2003-08-07 | 2004-08-09 | Homogene præparater af IL-29 |
| DK10173335.0T DK2251353T3 (da) | 2003-08-07 | 2004-08-09 | Homogene fremstillinger af IL-29 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04809553T DK1668031T3 (da) | 2003-08-07 | 2004-08-09 | Homogene præparater af IL-29 |
Country Status (15)
| Country | Link |
|---|---|
| US (38) | US7157559B2 (enExample) |
| EP (4) | EP2251353B1 (enExample) |
| JP (2) | JP4808157B2 (enExample) |
| CN (1) | CN1910200A (enExample) |
| AT (1) | ATE388963T1 (enExample) |
| AU (1) | AU2004270652B2 (enExample) |
| CA (1) | CA2534907C (enExample) |
| CY (1) | CY1114030T1 (enExample) |
| DE (1) | DE602004012424T2 (enExample) |
| DK (2) | DK1668031T3 (enExample) |
| ES (2) | ES2303132T3 (enExample) |
| IL (1) | IL210381A0 (enExample) |
| PL (1) | PL2251353T3 (enExample) |
| PT (1) | PT2251353E (enExample) |
| WO (1) | WO2005023862A2 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030219B2 (en) | 2000-04-28 | 2006-04-18 | Johns Hopkins University | B7-DC, Dendritic cell co-stimulatory molecules |
| EP2132984A3 (en) | 2000-06-30 | 2010-11-03 | ZymoGenetics, L.L.C. | Interferon-like protein ZCYTO21 |
| US7910313B2 (en) | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
| US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| WO2004037995A2 (en) * | 2002-10-23 | 2004-05-06 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 |
| EP1629105B1 (en) | 2003-04-29 | 2010-09-01 | AVI BioPharma, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
| EP2251353B1 (en) | 2003-08-07 | 2013-03-06 | ZymoGenetics, Inc. | Homogeneous preparations of IL-29 |
| GB0405634D0 (en) | 2004-03-12 | 2004-04-21 | Univ Southampton | Anti-virus therapy for respiratory diseases |
| US20050244423A1 (en) * | 2004-04-02 | 2005-11-03 | Klucher Kevin M | Methods for treating viral infection using IL-28 and IL-29 cysteine mutants |
| EP1793845A2 (en) | 2004-07-29 | 2007-06-13 | ZymoGenetics, Inc. | Use of il-28 and il-29 to treat cancer |
| ES2579758T3 (es) * | 2005-01-28 | 2016-08-16 | Zymogenetics, Inc. | Preparaciones homogéneas de IL-31 |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
| AU2006269908A1 (en) * | 2005-07-20 | 2007-01-25 | Bristol-Myers Squibb Company | IL28 and IL29 truncated cysteine mutants and antiviral methods of using same |
| CA2625208A1 (en) * | 2005-10-04 | 2007-04-12 | Zymogenetics, Inc. | Production and purification of il-29 |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| RU2562108C2 (ru) * | 2007-09-20 | 2015-09-10 | Коммонвелт Сайентифик Энд Индастриал Рисерч Органайзейшн | Новые цитокины птиц и кодирующие их генетические последовательности |
| US8354125B2 (en) | 2007-10-27 | 2013-01-15 | Grant Gallagher | Ex-vivo treatment of peripheral blood leukocytes with IFN-λ |
| WO2009071696A2 (en) | 2007-12-07 | 2009-06-11 | Zymogenetics, Inc. | Humanized antibody molecules specific for il-31 |
| CN105535961A (zh) | 2008-04-04 | 2016-05-04 | 宾夕法尼亚大学托管会 | 使用il-28和组合物的疫苗和免疫治疗及其使用方法 |
| AU2009255994B2 (en) * | 2008-06-05 | 2014-07-17 | Bristol-Myers Squibb Company | Use of pegylated Type III Interferons for the treatment of hepatitis C |
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| CN102559737A (zh) * | 2011-12-13 | 2012-07-11 | 江南大学 | 一种人白细胞介素29的变异体及其制备方法 |
| WO2014033266A1 (en) | 2012-08-31 | 2014-03-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection |
| CA2891974A1 (en) * | 2012-11-21 | 2014-05-30 | The Governors Of The University Of Alberta | Immunomodulatory peptides and methods of use thereof |
| US9464321B2 (en) * | 2013-03-15 | 2016-10-11 | Medical Diagnostic Laboratories, Llc | Methods and reagents that specifically detect, distinguish and quantify IFN-λ2 mRNA from IFN-λ3 mRNA in humans |
| US10246501B2 (en) | 2014-01-08 | 2019-04-02 | Prosit Sole Biotechnology (Beijing) Co, Ltd | Fusion polypeptides and methods of use |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
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| CN104672318A (zh) * | 2014-12-17 | 2015-06-03 | 江南大学 | 一种肽链第43位赖氨酸定点突变为亮氨酸的人白介素-29变异体 |
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| JP7187315B2 (ja) | 2015-11-04 | 2022-12-12 | アイガー・バイオファーマシューティカルズ・インコーポレイテッド | デルタ型肝炎ウイルス感染の処置 |
| ES2968038T3 (es) | 2015-12-23 | 2024-05-06 | Univ Johns Hopkins | Agonista GLP-1R de acción prolongada como terapia de afecciones neurológicas y neurodegenerativas |
| SMT202100335T1 (it) | 2016-02-19 | 2021-07-12 | Eiger Biopharmaceuticals Inc | Trattamento dell'infezione da virus dell'epatite con interferone lambda |
| CN106047806B (zh) * | 2016-08-19 | 2019-07-16 | 上海逍鹏生物科技有限公司 | 一种适用于高密度细胞培养体系的外周血细胞培养基 |
| MX2019003744A (es) * | 2016-09-30 | 2019-10-30 | Univ Leland Stanford Junior | Interferones de variante tipo iii y sintecinas. |
| ES3015227T3 (en) * | 2017-03-16 | 2025-04-30 | Evangelos Andreakos | Use of lambda interferons in the treatment of an obesity-related disorder, atherosclerosis or a coagulation disorder |
| CN107043740A (zh) * | 2017-05-10 | 2017-08-15 | 浙江美保龙生物技术有限公司 | 一种mdbk细胞培养液及其制备方法、使用方法 |
| CN107630086B (zh) * | 2017-11-13 | 2020-11-03 | 吉林大学 | 一种与hbv感染相关的snp分子标记及其应用 |
| CN108070647B (zh) * | 2017-12-25 | 2021-06-01 | 吉林大学 | 与hbv感染相关的基因单体型及其应用 |
| CN108570459B (zh) * | 2018-04-10 | 2022-10-04 | 南京农业大学 | 一种高效发酵生产重组细菌漆酶的方法 |
| CA3169594A1 (en) * | 2020-02-06 | 2021-08-12 | Eiger Biopharmaceuticals, Inc. | Treatment of coronavirus infection with interferon lambda |
| TW202146011A (zh) | 2020-03-05 | 2021-12-16 | 美商詹森藥物公司 | 治療b型肝炎病毒感染之組合療法 |
| TW202207950A (zh) | 2020-06-22 | 2022-03-01 | 美商詹森藥物公司 | 治療d型肝炎病毒感染之組合物及方法 |
| CN115385998B (zh) * | 2021-04-13 | 2025-08-05 | 杭州先为达生物科技股份有限公司 | 稳定的iii型干扰素蛋白及其融合蛋白 |
| CN116219078B (zh) * | 2023-05-08 | 2023-07-11 | 上海惠盾因泰生物科技有限公司 | 一种il-29生物学活性测定方法 |
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