DK2242743T3 - Aminopyrazolderivater - Google Patents
AminopyrazolderivaterInfo
- Publication number
- DK2242743T3 DK2242743T3 DK08862120.6T DK08862120T DK2242743T3 DK 2242743 T3 DK2242743 T3 DK 2242743T3 DK 08862120 T DK08862120 T DK 08862120T DK 2242743 T3 DK2242743 T3 DK 2242743T3
- Authority
- DK
- Denmark
- Prior art keywords
- aminopyrazole
- Prior art date
Links
- JVVRJMXHNUAPHW-UHFFFAOYSA-N 1h-pyrazol-5-amine Chemical compound NC=1C=CNN=1 JVVRJMXHNUAPHW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2007055111 | 2007-12-14 | ||
| IB2008053648 | 2008-09-10 | ||
| PCT/IB2008/055251 WO2009077954A1 (en) | 2007-12-14 | 2008-12-12 | Aminopyrazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2242743T3 true DK2242743T3 (da) | 2013-10-14 |
Family
ID=40456559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08862120.6T DK2242743T3 (da) | 2007-12-14 | 2008-12-12 | Aminopyrazolderivater |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8288419B2 (da) |
| EP (1) | EP2242743B1 (da) |
| JP (1) | JP5435744B2 (da) |
| KR (1) | KR101622413B1 (da) |
| CN (1) | CN101903353B (da) |
| AR (1) | AR069650A1 (da) |
| BR (1) | BRPI0821004A8 (da) |
| CA (1) | CA2706836C (da) |
| CY (1) | CY1114793T1 (da) |
| DK (1) | DK2242743T3 (da) |
| ES (1) | ES2432059T3 (da) |
| HK (1) | HK1148286A1 (da) |
| HR (1) | HRP20131105T1 (da) |
| IL (1) | IL206296A (da) |
| MA (1) | MA31988B1 (da) |
| MX (1) | MX2010005827A (da) |
| MY (1) | MY153921A (da) |
| NZ (1) | NZ586776A (da) |
| PL (1) | PL2242743T3 (da) |
| PT (1) | PT2242743E (da) |
| RU (1) | RU2489426C2 (da) |
| SI (1) | SI2242743T1 (da) |
| TW (1) | TWI430795B (da) |
| WO (1) | WO2009077954A1 (da) |
| ZA (1) | ZA201004939B (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2225231T1 (sl) | 2007-12-18 | 2011-12-30 | Actelion Pharmaceuticals Ltd | Derivati aminotriazola kot alx agonisti |
| ES2431298T3 (es) | 2009-05-18 | 2013-11-25 | Actelion Pharmaceuticals Ltd. | Derivados de espiro[2.4]heptano puenteados como agonistas del receptor de ALX y/o FPRL2 |
| BRPI1010738A8 (pt) | 2009-06-09 | 2017-12-26 | Actelion Pharmaceuticals Ltd | Derivados de aminotriazol fluorado |
| EP2440536B1 (en) | 2009-06-12 | 2013-11-06 | Actelion Pharmaceuticals Ltd. | Oxazole and thiazole derivatives as ALX receptor agonists |
| PE20130405A1 (es) | 2010-04-07 | 2013-04-10 | Hoffmann La Roche | Compuestos de pirazol-4-il-heterociclil-carboxamida y metodos de uso |
| KR101905927B1 (ko) | 2010-11-17 | 2018-10-08 | 이도르시아 파마슈티컬스 리미티드 | 가교된 스피로［２．４］헵탄 에스테르 유도체 |
| AU2011340103A1 (en) * | 2010-12-07 | 2013-07-25 | Actelion Pharmaceuticals Ltd. | Hydroxylated aminotriazole derivatives as ALX receptor agonists |
| CN103261194B (zh) | 2010-12-07 | 2016-02-24 | 埃科特莱茵药品有限公司 | 作为alx受体激动剂的噁唑基-甲醚衍生物 |
| EP2675801B1 (en) | 2011-02-18 | 2015-04-08 | Actelion Pharmaceuticals Ltd. | Novel pyrazole and imidazole derivatives useful as orexin antagonists |
| WO2012152741A1 (de) | 2011-05-10 | 2012-11-15 | Bayer Intellectual Property Gmbh | Bicyclische (thio)carbonylamidine |
| MX2014003612A (es) | 2011-09-27 | 2014-07-09 | Hoffmann La Roche | Compuestos de pirazol-4-il-heterociclil-carboxamida y metodos de uso. |
| DE102011055815A1 (de) | 2011-11-29 | 2013-05-29 | Aicuris Gmbh & Co. Kg | Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung |
| MA37618B1 (fr) | 2012-05-16 | 2017-08-31 | Actelion Pharmaceuticals Ltd | Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx |
| ES2596521T3 (es) | 2012-05-16 | 2017-01-10 | Actelion Pharmaceuticals Ltd. | Derivados de espiro[2.4]heptano sustituidos con puente 1-(p-tolil)ciclopropilo como agonistas de receptor de ALX |
| DE102012016908A1 (de) | 2012-08-17 | 2014-02-20 | Aicuris Gmbh & Co. Kg | Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung |
| AR096686A1 (es) | 2013-06-25 | 2016-01-27 | Actelion Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx |
| AU2014292064B2 (en) | 2013-07-18 | 2018-07-05 | Idorsia Pharmaceuticals Ltd | Piperazine substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists |
| AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| TN2016000210A1 (en) | 2013-11-28 | 2017-10-06 | Kyorin Seiyaku Kk | Urea derivative or pharmacologically acceptable salt thereof. |
| PE20180234A1 (es) | 2015-05-27 | 2018-01-31 | Kyorin Seiyaku Kk | Derivado de urea o sal farmacologicamente aceptable del mismo |
| JP6746614B2 (ja) | 2015-05-27 | 2020-08-26 | 杏林製薬株式会社 | ウレア誘導体、またはその薬理学的に許容される塩 |
| IL277044B2 (en) | 2018-03-05 | 2023-10-01 | Bristol Myers Squibb Co | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
| AU2019247533B2 (en) * | 2018-04-06 | 2023-09-28 | Altos Labs, Inc. | ATF6 inhibitors and uses thereof |
| WO2023118434A1 (en) * | 2021-12-22 | 2023-06-29 | Globachem Nv | Pesticidally active amide compounds |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8531019D0 (en) * | 1985-12-17 | 1986-01-29 | Beecham Group Plc | Compounds |
| JPS62234018A (ja) | 1986-04-02 | 1987-10-14 | Rooto Seiyaku Kk | 糖尿病併発症治療剤 |
| DE60014603T2 (de) * | 1999-03-12 | 2006-02-16 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Heterocyklischer harnstoff und verwandte verbindungen als entzündungshemmende mittel |
| KR20030030029A (ko) | 2000-09-22 | 2003-04-16 | 니혼노야쿠가부시키가이샤 | Ｎ-(4-피라졸릴)아미드 유도체 및 농원예용 약제 그리고그 사용방법 |
| JP2004526721A (ja) * | 2001-03-02 | 2004-09-02 | エフ．ホフマン−ラ ロシュ アーゲー | Ｉｐアンタゴニストとしてのアルコキシカルボニルアミノヘテロアリールカルボン酸誘導体 |
| WO2003082314A2 (en) | 2002-04-03 | 2003-10-09 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1) |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| AU2004290368A1 (en) | 2003-11-07 | 2005-05-26 | Acadia Pharmaceuticals Inc. | Use of the lipoxin receptor, FPRL1, as a tool for identifying compounds effective in the treatment of pain and inflammation |
| GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
| CA2626897A1 (en) | 2005-11-03 | 2007-05-18 | Joshua Close | Histone deacetylase inhibitors with aryl-pyrazolyl motifs |
| GB0606876D0 (en) * | 2006-04-05 | 2006-05-17 | Glaxo Group Ltd | Compounds |
| CA2696995C (en) | 2007-08-21 | 2017-11-21 | Senomyx, Inc. | Identification of human t2r receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof |
| SI2225231T1 (sl) | 2007-12-18 | 2011-12-30 | Actelion Pharmaceuticals Ltd | Derivati aminotriazola kot alx agonisti |
| ES2431298T3 (es) | 2009-05-18 | 2013-11-25 | Actelion Pharmaceuticals Ltd. | Derivados de espiro[2.4]heptano puenteados como agonistas del receptor de ALX y/o FPRL2 |
| BRPI1010738A8 (pt) | 2009-06-09 | 2017-12-26 | Actelion Pharmaceuticals Ltd | Derivados de aminotriazol fluorado |
| EP2440536B1 (en) | 2009-06-12 | 2013-11-06 | Actelion Pharmaceuticals Ltd. | Oxazole and thiazole derivatives as ALX receptor agonists |
-
2008
- 2008-12-11 AR ARP080105380A patent/AR069650A1/es unknown
- 2008-12-12 RU RU2010128240/04A patent/RU2489426C2/ru not_active IP Right Cessation
- 2008-12-12 MX MX2010005827A patent/MX2010005827A/es active IP Right Grant
- 2008-12-12 US US12/808,137 patent/US8288419B2/en not_active Expired - Fee Related
- 2008-12-12 PT PT88621206T patent/PT2242743E/pt unknown
- 2008-12-12 ES ES08862120T patent/ES2432059T3/es active Active
- 2008-12-12 EP EP08862120.6A patent/EP2242743B1/en not_active Not-in-force
- 2008-12-12 WO PCT/IB2008/055251 patent/WO2009077954A1/en active Application Filing
- 2008-12-12 NZ NZ586776A patent/NZ586776A/en not_active IP Right Cessation
- 2008-12-12 JP JP2010537589A patent/JP5435744B2/ja not_active Expired - Fee Related
- 2008-12-12 KR KR1020107015524A patent/KR101622413B1/ko not_active IP Right Cessation
- 2008-12-12 BR BRPI0821004A patent/BRPI0821004A8/pt not_active IP Right Cessation
- 2008-12-12 PL PL08862120T patent/PL2242743T3/pl unknown
- 2008-12-12 MY MYPI2010002723A patent/MY153921A/en unknown
- 2008-12-12 TW TW097148594A patent/TWI430795B/zh not_active IP Right Cessation
- 2008-12-12 DK DK08862120.6T patent/DK2242743T3/da active
- 2008-12-12 SI SI200831072T patent/SI2242743T1/sl unknown
- 2008-12-12 CN CN2008801219752A patent/CN101903353B/zh not_active Expired - Fee Related
- 2008-12-12 CA CA2706836A patent/CA2706836C/en not_active Expired - Fee Related
-
2010
- 2010-06-10 IL IL206296A patent/IL206296A/en not_active IP Right Cessation
- 2010-06-29 MA MA32967A patent/MA31988B1/fr unknown
- 2010-07-13 ZA ZA2010/04939A patent/ZA201004939B/en unknown
-
2011
- 2011-03-11 HK HK11102486.4A patent/HK1148286A1/xx not_active IP Right Cessation
-
2013
- 2013-11-20 HR HRP20131105AT patent/HRP20131105T1/hr unknown
- 2013-11-20 CY CY20131101025T patent/CY1114793T1/el unknown
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