DK2215225T3 - IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic - Google Patents

IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic Download PDF

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Publication number
DK2215225T3
DK2215225T3 DK08843625.8T DK08843625T DK2215225T3 DK 2215225 T3 DK2215225 T3 DK 2215225T3 DK 08843625 T DK08843625 T DK 08843625T DK 2215225 T3 DK2215225 T3 DK 2215225T3
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gly
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DK08843625.8T
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Danish (da)
English (en)
Inventor
Robert Dicosimo
Arie Ben-Bassat
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Du Pont
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Publication of DK2215225T3 publication Critical patent/DK2215225T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/584Recycling of catalysts

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK08843625.8T 2007-10-31 2008-10-31 IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic DK2215225T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/930,550 US7695945B2 (en) 2007-10-31 2007-10-31 Immobilized microbial nitrilase for production of glycolic acid
PCT/US2008/081948 WO2009059101A1 (en) 2007-10-31 2008-10-31 Improvement in immobilized microbial nitrilase for production of glycolic acid

Publications (1)

Publication Number Publication Date
DK2215225T3 true DK2215225T3 (en) 2016-03-07

Family

ID=40243876

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08843625.8T DK2215225T3 (en) 2007-10-31 2008-10-31 IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic

Country Status (8)

Country Link
US (1) US7695945B2 (enExample)
EP (1) EP2215225B1 (enExample)
JP (1) JP5702604B2 (enExample)
CN (1) CN101965399B (enExample)
DK (1) DK2215225T3 (enExample)
ES (1) ES2563482T3 (enExample)
PL (1) PL2215225T3 (enExample)
WO (1) WO2009059101A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012048865A2 (de) 2010-10-12 2012-04-19 C-Lecta Gmbh Nitrilasen
GB2554708A (en) * 2016-10-05 2018-04-11 Chemoxy Int Process for converting nitriles
CN111848495B (zh) * 2020-06-02 2022-06-21 山东华素制药有限公司 一种1-苄基-3-哌啶醇的合成方法
CN115845880B (zh) * 2022-12-08 2024-06-14 复旦大学 一种水溶性高分子模板原位构筑过渡金属硫化物/碳复合材料及其制备方法和应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2175805A (en) * 1937-06-08 1939-10-10 Du Pont Stabilized organic nitrile and process of making
US2890238A (en) * 1957-01-31 1959-06-09 Dow Chemical Co Preparation of glyconitrile
GB1553662A (en) 1978-04-13 1979-09-26 Union Carbide Corp Sterilization of fermentation media
DK146942C (da) * 1978-04-19 1984-07-30 Novo Industri As Fremgangsmaade til fremstilling af et immobiliseret enzymprodukt
US4355105A (en) * 1981-03-30 1982-10-19 Miles Laboratories, Inc. Glutaraldehyde/polyethylenimine immobilization of whole microbial cells
US5187301A (en) * 1989-10-26 1993-02-16 W. R. Grace & Co.-Conn. Preparation of iminodiacetonitrile from glycolonitrile
DE69126762T2 (de) * 1990-11-14 1997-10-23 Nitto Chemical Industry Co Ltd Biologisches Verfahren zur Herstellung von Alpha-Hydroxyamid und Alpha-Hydroxysäure
JP3354688B2 (ja) * 1994-01-28 2002-12-09 三菱レイヨン株式会社 微生物によるα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法
US6037155A (en) * 1997-02-27 2000-03-14 Nippon Soda Co., Ltd. Process for preparing α-hydroxy acids using microorganism and novel microorganism
US6251646B1 (en) * 1999-07-12 2001-06-26 E. I. Du Pont De Nemours And Company Method for stabilizing nitrilase activity and preserving microbial cells
US6551804B2 (en) * 1999-07-12 2003-04-22 E. I. Du Pont De Nemours And Company Process for preparing 4-cyanopentanoic acid
KR100501864B1 (ko) * 1999-11-12 2005-07-20 미츠비시 레이온 가부시키가이샤 사멸화 균체
ATE495244T1 (de) * 2000-03-31 2011-01-15 Du Pont Isolierung und expression eines nitrilase-gens von acidovorax facilis 72w
US6416980B1 (en) * 2001-02-23 2002-07-09 E. I. Du Pont De Nemours & Company Method for producing glycolic acid from glycolonitrile using nitrilase
KR100869623B1 (ko) 2004-04-27 2008-11-21 미쓰이 가가쿠 가부시키가이샤 하이드록시 카복실산류의 생산 방법
US7148051B2 (en) * 2004-08-16 2006-12-12 E. I. Du Pont De Nemours And Company Production of 3-hydroxycarboxylic acid using nitrilase
EP1828393B1 (en) 2004-12-22 2012-11-07 E.I. Du Pont De Nemours And Company Process for producing glycolic acid from formaldehyde and hydrogen cyanide
US7198927B2 (en) * 2004-12-22 2007-04-03 E. I. Du Pont De Nemours And Company Enzymatic production of glycolic acid
WO2006071663A1 (en) * 2004-12-22 2006-07-06 E.I. Dupont De Nemours And Company Process for the synthesis of glycolonitrile
US7445917B2 (en) * 2004-12-22 2008-11-04 E.I. Du Pont De Nemours And Company Process for producing glycolic acid from formaldehyde and hydrogen cyanide
CN101278047B (zh) * 2005-09-30 2012-12-12 诺维信公司 酶的固定化

Also Published As

Publication number Publication date
US20090111158A1 (en) 2009-04-30
US7695945B2 (en) 2010-04-13
CN101965399B (zh) 2016-06-08
PL2215225T3 (pl) 2016-05-31
EP2215225B1 (en) 2015-12-02
JP5702604B2 (ja) 2015-04-15
JP2011501969A (ja) 2011-01-20
WO2009059101A1 (en) 2009-05-07
EP2215225A1 (en) 2010-08-11
ES2563482T3 (es) 2016-03-15
CN101965399A (zh) 2011-02-02

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DK2215225T3 (en) IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic