DK2188291T3 - Fusionerede bicykliske pyrimidiner - Google Patents
Fusionerede bicykliske pyrimidinerInfo
- Publication number
- DK2188291T3 DK2188291T3 DK08787224.8T DK08787224T DK2188291T3 DK 2188291 T3 DK2188291 T3 DK 2188291T3 DK 08787224 T DK08787224 T DK 08787224T DK 2188291 T3 DK2188291 T3 DK 2188291T3
- Authority
- DK
- Denmark
- Prior art keywords
- fused bicyclic
- bicyclic pyrimidines
- pyrimidines
- fused
- bicyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1572MU2007 | 2007-08-14 | ||
| EP07118736A EP2050748A1 (en) | 2007-10-18 | 2007-10-18 | Novel fused pyrimidines |
| PCT/EP2008/060690 WO2009021992A2 (en) | 2007-08-14 | 2008-08-14 | Fused bicyclic pyrimidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2188291T3 true DK2188291T3 (da) | 2013-01-07 |
Family
ID=40153211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08787224.8T DK2188291T3 (da) | 2007-08-14 | 2008-08-14 | Fusionerede bicykliske pyrimidiner |
Country Status (38)
| Country | Link |
|---|---|
| US (2) | US7776864B2 (da) |
| EP (1) | EP2188291B1 (da) |
| JP (1) | JP5344637B2 (da) |
| KR (1) | KR20100053556A (da) |
| CN (1) | CN101778851B (da) |
| AR (1) | AR067945A1 (da) |
| AU (1) | AU2008288392B2 (da) |
| BR (1) | BRPI0815207A2 (da) |
| CA (1) | CA2694058C (da) |
| CL (1) | CL2008002398A1 (da) |
| CO (1) | CO6260077A2 (da) |
| CR (1) | CR11270A (da) |
| CY (1) | CY1113486T1 (da) |
| DK (1) | DK2188291T3 (da) |
| DO (1) | DOP2010000058A (da) |
| EA (1) | EA020996B1 (da) |
| EC (1) | ECSP109964A (da) |
| ES (1) | ES2396177T3 (da) |
| HK (1) | HK1146273A1 (da) |
| HN (1) | HN2010000313A (da) |
| HR (1) | HRP20121022T1 (da) |
| IL (1) | IL203163A (da) |
| MA (1) | MA31608B1 (da) |
| MX (1) | MX2010001746A (da) |
| MY (1) | MY169738A (da) |
| NZ (1) | NZ583267A (da) |
| PA (1) | PA8793201A1 (da) |
| PE (1) | PE20090944A1 (da) |
| PL (1) | PL2188291T3 (da) |
| PT (1) | PT2188291E (da) |
| RS (1) | RS52559B (da) |
| SI (1) | SI2188291T1 (da) |
| SV (1) | SV2010003483A (da) |
| TN (1) | TN2010000070A1 (da) |
| TW (1) | TWI439272B (da) |
| UA (1) | UA99735C2 (da) |
| UY (1) | UY31293A1 (da) |
| WO (1) | WO2009021992A2 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7652133B2 (en) * | 2006-10-19 | 2010-01-26 | Takeda Pharmaceutical Company Limited | Indole compound |
| CL2008002398A1 (es) | 2007-08-14 | 2009-07-31 | Bayer Ip Gmbh | Compuestos derivados de 6-(fenil piperidina) pirimidinas fusionadas con imidazol, triazol o pirozol, inhibidores de la via pi3k/akt; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para el tratamiento de la neoplasia benigna y/o maligna y para el cancer. |
| EP2307400B1 (en) | 2008-05-30 | 2014-04-23 | Amgen, Inc | Inhibitors of pi3 kinase |
| AU2010213192A1 (en) | 2009-02-13 | 2011-08-04 | Bayer Intellectual Property Gmbh | Fused pyrimidines |
| ES2435804T3 (es) * | 2009-02-13 | 2013-12-23 | Bayer Intellectual Property Gmbh | Pirimidinas condensadas como inhibidores de Akt |
| WO2010114780A1 (en) | 2009-04-01 | 2010-10-07 | Merck Sharp & Dohme Corp. | Inhibitors of akt activity |
| WO2010125799A1 (ja) | 2009-04-27 | 2010-11-04 | 塩野義製薬株式会社 | Pi3k阻害活性を有するウレア誘導体 |
| CA2805015A1 (en) * | 2010-07-13 | 2012-01-19 | Stuart Ince | Bicyclic pyrimidines |
| WO2012013713A2 (en) | 2010-07-28 | 2012-02-02 | Bayer Pharma Aktiengesellschaft | Substituted imidazo[1,2-b]pyridazines |
| CN103596957B (zh) | 2011-04-07 | 2016-12-07 | 拜耳知识产权有限责任公司 | 作为akt激酶抑制剂的咪唑并哒嗪 |
| RU2644769C2 (ru) | 2013-01-23 | 2018-02-14 | Астразенека Аб | Химические соединения |
| US20140274685A1 (en) | 2013-03-15 | 2014-09-18 | Bayer Cropscience Lp | Compositions, additives, and methods for mitigating or controlling seed dust |
| WO2014146144A2 (en) * | 2013-03-15 | 2014-09-18 | Bayer Cropscience Lp | Compositions, additives, and methods for mitigating or controlling seed dust |
| MA50256A (fr) | 2017-09-15 | 2020-07-22 | Aduro Biotech Inc | Composés de pyrazolopyrimidinone et leurs utilisations |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0300798A3 (en) | 2000-06-30 | 2006-02-28 | Wyeth Corp | Substituted-triazolopyrimidines and their use as anticancer agents and pharmaceutical compositions containing them |
| US7449488B2 (en) * | 2002-06-04 | 2008-11-11 | Schering Corporation | Pyrazolopyrimidines as protein kinase inhibitors |
| US7579355B2 (en) | 2003-04-24 | 2009-08-25 | Merck & Co., Inc. | Inhibitors of Akt activity |
| CA2561311A1 (en) * | 2004-04-09 | 2005-10-27 | Merck & Co., Inc. | Inhibitors of akt activity |
| AR050188A1 (es) * | 2004-08-03 | 2006-10-04 | Uriach Y Compania S A J | Compuestos heterociclicos condensados utiles en terapia como inhibidores de quinasas p38 y composiciones farmaceuticas que los contienen |
| US7544677B2 (en) * | 2004-08-23 | 2009-06-09 | Merck & Co., Inc. | Inhibitors of Akt activity |
| CN101242834A (zh) | 2004-12-15 | 2008-08-13 | 默克公司 | Akt活性抑制剂 |
| JP5274842B2 (ja) * | 2004-12-28 | 2013-08-28 | エグゼリクシス， インコーポレイテッド | 免疫疾患、炎症疾患および増殖疾患の処置のためのセリン−スレオニンキナーゼモジュレーター（ｐ７０Ｓ６Ｋ、Ａｋｔ−１およびＡｋｔ−２）としての［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジンまたは［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジン化合物 |
| CN101115479A (zh) | 2005-02-14 | 2008-01-30 | 默克公司 | Akt活性抑制剂 |
| MX2007015578A (es) | 2005-06-10 | 2008-03-06 | Merck & Co Inc | Inhibidores de la actividad akt. |
| CL2008002398A1 (es) | 2007-08-14 | 2009-07-31 | Bayer Ip Gmbh | Compuestos derivados de 6-(fenil piperidina) pirimidinas fusionadas con imidazol, triazol o pirozol, inhibidores de la via pi3k/akt; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para el tratamiento de la neoplasia benigna y/o maligna y para el cancer. |
| AU2010213192A1 (en) * | 2009-02-13 | 2011-08-04 | Bayer Intellectual Property Gmbh | Fused pyrimidines |
-
2008
- 2008-08-14 CL CL2008002398A patent/CL2008002398A1/es unknown
- 2008-08-14 NZ NZ583267A patent/NZ583267A/en not_active IP Right Cessation
- 2008-08-14 MY MYPI2010000150A patent/MY169738A/en unknown
- 2008-08-14 TW TW097131066A patent/TWI439272B/zh not_active IP Right Cessation
- 2008-08-14 UY UY31293A patent/UY31293A1/es not_active Application Discontinuation
- 2008-08-14 AU AU2008288392A patent/AU2008288392B2/en not_active Ceased
- 2008-08-14 JP JP2010520586A patent/JP5344637B2/ja not_active Expired - Fee Related
- 2008-08-14 PA PA20088793201A patent/PA8793201A1/es unknown
- 2008-08-14 ES ES08787224T patent/ES2396177T3/es active Active
- 2008-08-14 PE PE2008001378A patent/PE20090944A1/es not_active Application Discontinuation
- 2008-08-14 DK DK08787224.8T patent/DK2188291T3/da active
- 2008-08-14 MX MX2010001746A patent/MX2010001746A/es active IP Right Grant
- 2008-08-14 PL PL08787224T patent/PL2188291T3/pl unknown
- 2008-08-14 WO PCT/EP2008/060690 patent/WO2009021992A2/en active Application Filing
- 2008-08-14 CN CN2008801031086A patent/CN101778851B/zh not_active Expired - Fee Related
- 2008-08-14 SI SI200830848T patent/SI2188291T1/sl unknown
- 2008-08-14 KR KR1020107003246A patent/KR20100053556A/ko active IP Right Grant
- 2008-08-14 UA UAA201002746A patent/UA99735C2/uk unknown
- 2008-08-14 EA EA201000298A patent/EA020996B1/ru not_active IP Right Cessation
- 2008-08-14 EP EP08787224A patent/EP2188291B1/en active Active
- 2008-08-14 US US12/191,703 patent/US7776864B2/en not_active Expired - Fee Related
- 2008-08-14 PT PT87872248T patent/PT2188291E/pt unknown
- 2008-08-14 RS RS20120556A patent/RS52559B/en unknown
- 2008-08-14 CA CA2694058A patent/CA2694058C/en not_active Expired - Fee Related
- 2008-08-14 BR BRPI0815207A patent/BRPI0815207A2/pt not_active IP Right Cessation
- 2008-08-15 AR ARP080103562A patent/AR067945A1/es unknown
-
2010
- 2010-01-06 IL IL203163A patent/IL203163A/en not_active IP Right Cessation
- 2010-02-12 CO CO10015919A patent/CO6260077A2/es active IP Right Grant
- 2010-02-12 HN HN2010000313A patent/HN2010000313A/es unknown
- 2010-02-12 SV SV2010003483A patent/SV2010003483A/es unknown
- 2010-02-12 CR CR11270A patent/CR11270A/es unknown
- 2010-02-12 TN TNP2010000070A patent/TN2010000070A1/fr unknown
- 2010-02-12 MA MA32617A patent/MA31608B1/fr unknown
- 2010-02-12 DO DO2010000058A patent/DOP2010000058A/es unknown
- 2010-02-12 EC EC2010009964A patent/ECSP109964A/es unknown
- 2010-03-25 US US12/731,880 patent/US8614218B2/en not_active Expired - Fee Related
-
2011
- 2011-01-14 HK HK11100395.8A patent/HK1146273A1/xx not_active IP Right Cessation
-
2012
- 2012-12-12 HR HRP20121022AT patent/HRP20121022T1/hr unknown
- 2012-12-13 CY CY20121101220T patent/CY1113486T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2188291T3 (da) | Fusionerede bicykliske pyrimidiner | |
| BRPI0815037A2 (pt) | Composto bicíclico fundido | |
| DK2154967T3 (da) | Pyrimidinderivater | |
| BRPI0809643A2 (pt) | Derivados de heteroarila bicíclica fundida | |
| DE112008002410A5 (de) | Glasscheiben-Geländer | |
| BRPI1009398A2 (pt) | compostos de pirimidina fundida substituída | |
| DE602008002748D1 (de) | Linseneinführsystem | |
| BRPI0907435A2 (pt) | Derivados de 5-flúor pirimidina | |
| DE602008000004D1 (de) | Linseneinführsystem | |
| BRPI0815077A2 (pt) | Heterocíclicos fundidos | |
| DK2242743T3 (da) | Aminopyrazolderivater | |
| HK1165423A1 (en) | Fused pyrimidines | |
| DK1957492T3 (da) | Substituerede bicykliske pyrimidonderivater | |
| BRPI0811115A2 (pt) | Compostos de heteroarilamida pirimidona | |
| BRPI0920496A2 (pt) | derivados substituídos de pirimidina etriazina | |
| CU20090141A7 (es) | Compuestos 2-amino pirimidina | |
| BRPI0821142A2 (pt) | derivados heterocíclicos bicíclicos | |
| BRPI0811094A2 (pt) | Derivados de heteroarilamida pirimidona | |
| BRPI0811611A2 (pt) | Compostos de triazolil aminopirimidina | |
| ATE519980T1 (de) | Verbinder | |
| ES1066007Y (es) | Gafas | |
| CN300862083S (zh) | 眼镜 | |
| CN300839231S (zh) | 眼镜 | |
| UA16433S (uk) | Стакан | |
| UA16301S (uk) | Стакан |