DK2158313T3 - Fungale peroxygenaser og fremgangsmåder til anvendelse heraf - Google Patents
Fungale peroxygenaser og fremgangsmåder til anvendelse herafInfo
- Publication number
- DK2158313T3 DK2158313T3 DK08718350.5T DK08718350T DK2158313T3 DK 2158313 T3 DK2158313 T3 DK 2158313T3 DK 08718350 T DK08718350 T DK 08718350T DK 2158313 T3 DK2158313 T3 DK 2158313T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- polypeptides
- formula
- heterocycles
- polynucleotides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007016139A DE102007016139A1 (de) | 2007-03-30 | 2007-03-30 | Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen |
| PCT/EP2008/053798 WO2008119780A2 (en) | 2007-03-30 | 2008-03-31 | Fungal peroxygenases and methods of application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2158313T3 true DK2158313T3 (da) | 2012-05-14 |
Family
ID=39591196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08718350.5T DK2158313T3 (da) | 2007-03-30 | 2008-03-31 | Fungale peroxygenaser og fremgangsmåder til anvendelse heraf |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8367387B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2158313B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5411121B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101802180B (cg-RX-API-DMAC7.html) |
| AT (1) | ATE548449T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2682451C (cg-RX-API-DMAC7.html) |
| DE (1) | DE102007016139A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2158313T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008119780A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9222109B2 (en) | 2010-03-28 | 2015-12-29 | Novozymes A/S | Enzymatic hydroxylation of aliphatic hydrocarbon |
| US20140234917A1 (en) | 2011-07-07 | 2014-08-21 | Novozymes A/S | Enzymatic Preparation of Diols |
| WO2013021059A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021064A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9506044B2 (en) | 2011-08-10 | 2016-11-29 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| EP2742129B1 (en) | 2011-08-10 | 2017-08-02 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021062A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021065A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021063A2 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013079533A1 (en) | 2011-12-02 | 2013-06-06 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9169469B2 (en) * | 2011-12-02 | 2015-10-27 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9458478B2 (en) | 2012-03-31 | 2016-10-04 | Novozymes A/S | Epoxidation using peroxygenase |
| BR112014032865A2 (pt) | 2012-07-18 | 2017-08-01 | Novozymes As | método para tratamento de têxtil de poliéster, e, composição |
| CN104781412A (zh) | 2012-07-20 | 2015-07-15 | 诺维信公司 | 5-羟甲基糠醛及其衍生物的酶氧化 |
| CN104718286B (zh) | 2012-10-12 | 2018-10-30 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| CN104718287B (zh) * | 2012-10-12 | 2018-02-06 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| EP2906687B1 (en) * | 2012-10-12 | 2018-08-15 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014056917A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| CN104718288B (zh) * | 2012-10-12 | 2018-11-16 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| WO2014056920A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9499802B2 (en) | 2012-10-12 | 2016-11-22 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9458435B2 (en) | 2012-10-12 | 2016-10-04 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014090940A1 (en) * | 2012-12-14 | 2014-06-19 | Novozymes A/S | Removal of skin-derived body soils |
| EP2871233A1 (de) | 2013-11-12 | 2015-05-13 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur Herstellung von biogenen Stoffen |
| WO2015074072A1 (en) * | 2013-11-18 | 2015-05-21 | Enzymatic Deinking Technologies, Llc | Enzymatic treatment of virgin fiber and recycled paper to reduce residual mineral oil levels for paper production |
| US10465172B2 (en) * | 2013-11-29 | 2019-11-05 | Novozymes A/S | Peroxygenase variants |
| WO2016207373A1 (en) | 2015-06-26 | 2016-12-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| EP3392341B1 (en) | 2017-04-20 | 2021-03-10 | Consejo Superior de Investigaciones Científicas (CSIC) | Process for shortening the hydrocarbon chain of a carboxylic acid by a peroxygenase |
| NL2021113B1 (en) | 2018-06-13 | 2019-12-19 | Univ Delft Tech | Synthesis of aromatic epoxide derived compounds |
| EP3818164B1 (en) * | 2018-07-03 | 2023-08-02 | Ruhr-Universität Bochum | Plasma-driven biocatalysis |
| EP3594332A1 (en) * | 2018-07-10 | 2020-01-15 | Consejo Superior de Investigaciones Cientificas | Method of heterologous expression of active fungal unspecific peroxygenase in bacterial host cells for fatty-acid epoxidation and other oxygenation reactions |
| EP3660147A1 (en) | 2018-11-30 | 2020-06-03 | Consejo Superior de Investigaciones Cientificas (CSIC) | Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases |
| US20220064516A1 (en) * | 2019-01-03 | 2022-03-03 | Locus Oil Ip Company, Llc | Materials and Methods for Extended Reduction of Heavy Crude Oil Viscosity |
| EP3994252A1 (en) | 2019-07-05 | 2022-05-11 | bisy GmbH | Recombinant heme thiolate oxygenases |
| US20240010996A1 (en) | 2020-09-23 | 2024-01-11 | Gecco Biotech B.V. | Bacterial unspecific peroxygenases (BUPO's) and methods and uses thereof |
| DE102021204094A1 (de) | 2021-04-25 | 2022-10-27 | Brandenburgische Technische Universität Cottbus-Senftenberg | In-vitro Arzneimittel aus Prodrugs und deren Verwendung |
| WO2023031462A1 (de) | 2021-09-03 | 2023-03-09 | Brandenburgische Technische Universitaet Cottbus-Senftenberg | Verfahren zur zellfreien herstellung von unspezifischen peroxygenasen |
| DE102021214582A1 (de) | 2021-12-17 | 2023-06-22 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| DE102021209758A1 (de) | 2021-09-03 | 2023-03-09 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| CN116240246B (zh) * | 2021-12-20 | 2025-01-21 | 浙江金朗博药业有限公司 | 利用过氧化物酶合成骨化二醇的方法 |
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|---|---|---|---|---|
| GB1296839A (cg-RX-API-DMAC7.html) | 1969-05-29 | 1972-11-22 | ||
| GB1372034A (en) | 1970-12-31 | 1974-10-30 | Unilever Ltd | Detergent compositions |
| US3826746A (en) | 1972-07-18 | 1974-07-30 | Mobil Oil Corp | Lubricant compositions |
| GB1483591A (en) | 1973-07-23 | 1977-08-24 | Novo Industri As | Process for coating water soluble or water dispersible particles by means of the fluid bed technique |
| GB1590432A (en) | 1976-07-07 | 1981-06-03 | Novo Industri As | Process for the production of an enzyme granulate and the enzyme granuate thus produced |
| DK187280A (da) | 1980-04-30 | 1981-10-31 | Novo Industri As | Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode |
| US4353985A (en) | 1980-07-14 | 1982-10-12 | Schering Aktiengesellschaft | Process for the preparation of 11 β-hydroxy steroids |
| DK263584D0 (da) | 1984-05-29 | 1984-05-29 | Novo Industri As | Enzymholdige granulater anvendt som detergentadditiver |
| EP0218272B1 (en) | 1985-08-09 | 1992-03-18 | Gist-Brocades N.V. | Novel lipolytic enzymes and their use in detergent compositions |
| EG18543A (en) | 1986-02-20 | 1993-07-30 | Albright & Wilson | Protected enzyme systems |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US4810414A (en) | 1986-08-29 | 1989-03-07 | Novo Industri A/S | Enzymatic detergent additive |
| NZ221627A (en) | 1986-09-09 | 1993-04-28 | Genencor Inc | Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios |
| ES2076939T3 (es) | 1987-08-28 | 1995-11-16 | Novo Nordisk As | Lipasa recombinante de humicola y procedimiento para la produccion de lipasas recombinantes de humicola. |
| JPS6474992A (en) | 1987-09-16 | 1989-03-20 | Fuji Oil Co Ltd | Dna sequence, plasmid and production of lipase |
| EP0471265B1 (en) | 1988-01-07 | 1995-10-25 | Novo Nordisk A/S | Specific protease |
| DK6488D0 (da) | 1988-01-07 | 1988-01-07 | Novo Industri As | Enzymer |
| JP3079276B2 (ja) | 1988-02-28 | 2000-08-21 | 天野製薬株式会社 | 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法 |
| DE68911131T2 (de) | 1988-03-24 | 1994-03-31 | Novonordisk As | Cellulosezubereitung. |
| US5776757A (en) | 1988-03-24 | 1998-07-07 | Novo Nordisk A/S | Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8915658D0 (en) | 1989-07-07 | 1989-08-23 | Unilever Plc | Enzymes,their production and use |
| IL97645A (en) | 1990-03-23 | 1997-03-18 | Gist Brocades Nv | Production of enzymes in seeds and their use |
| KR100236540B1 (ko) | 1990-04-14 | 2000-01-15 | 레클로우크스 라우에르 | 알카리성 바실러스-리파제, 이를 코-딩하는 dna 서열 및 리파제를 생산하는 바실러스 균주 |
| DK0531372T4 (da) | 1990-05-09 | 2004-08-09 | Novozymes As | Cellulasepræparat omfattende et endoglucanaseenzym |
| DK115890D0 (da) | 1990-05-09 | 1990-05-09 | Novo Nordisk As | Enzym |
| AU657278B2 (en) | 1990-09-13 | 1995-03-09 | Novo Nordisk A/S | Lipase variants |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| ES2174820T3 (es) | 1991-01-16 | 2002-11-16 | Procter & Gamble | Composiciones detergentes compactas con celulasa de alta actividad. |
| EP0511456A1 (en) | 1991-04-30 | 1992-11-04 | The Procter & Gamble Company | Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme |
| WO1992019709A1 (en) | 1991-04-30 | 1992-11-12 | The Procter & Gamble Company | Built liquid detergents with boric-polyol complex to inhibit proteolytic enzyme |
| KR100258460B1 (ko) | 1991-05-01 | 2000-06-01 | 한센 핀 베네드 | 안정화 효소 및 세제 조성물 |
| DK72992D0 (da) | 1992-06-01 | 1992-06-01 | Novo Nordisk As | Enzym |
| DK88892D0 (da) | 1992-07-06 | 1992-07-06 | Novo Nordisk As | Forbindelse |
| KR100294361B1 (ko) | 1992-07-23 | 2001-09-17 | 피아 스타르 | 돌연변이체알파-아밀라제,세정제,접시세척제,및액화제 |
| EP0663950B1 (en) | 1992-10-06 | 2004-03-17 | Novozymes A/S | Cellulase variants |
| PT867504E (pt) | 1993-02-11 | 2003-08-29 | Genencor Int | Alfa-amilase estavel a oxidacao |
| CN1108457A (zh) | 1993-04-27 | 1995-09-13 | 吉斯特·布罗卡迪斯股份有限公司 | 用于洗涤剂领域的新的脂酶变异体 |
| DK52393D0 (cg-RX-API-DMAC7.html) | 1993-05-05 | 1993-05-05 | Novo Nordisk As | |
| JP2859520B2 (ja) | 1993-08-30 | 1999-02-17 | ノボ ノルディスク アクティーゼルスカブ | リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物 |
| US5817495A (en) | 1993-10-13 | 1998-10-06 | Novo Nordisk A/S | H2 O2 -stable peroxidase variants |
| JPH07143883A (ja) | 1993-11-24 | 1995-06-06 | Showa Denko Kk | リパーゼ遺伝子及び変異体リパーゼ |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| AU1806795A (en) | 1994-02-22 | 1995-09-04 | Novo Nordisk A/S | A method of preparing a variant of a lipolytic enzyme |
| EP0749473B1 (en) | 1994-03-08 | 2005-10-12 | Novozymes A/S | Novel alkaline cellulases |
| AU2524695A (en) | 1994-05-04 | 1995-11-29 | Genencor International, Inc. | Lipases with improved surfactant resistance |
| CN1192108C (zh) | 1994-06-03 | 2005-03-09 | 诺沃奇梅兹生物技术有限公司 | 纯化的毁丝霉属漆酶及编码该酶的核酸 |
| AU2884595A (en) | 1994-06-20 | 1996-01-15 | Unilever Plc | Modified pseudomonas lipases and their use |
| AU2884695A (en) | 1994-06-23 | 1996-01-19 | Unilever Plc | Modified pseudomonas lipases and their use |
| EP1559776A3 (en) | 1994-06-30 | 2006-01-11 | Novozymes Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein |
| ATE389012T1 (de) | 1994-10-06 | 2008-03-15 | Novozymes As | Ein enzympräparat mit endoglucanase aktivität |
| BE1008998A3 (fr) | 1994-10-14 | 1996-10-01 | Solvay | Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci. |
| JPH10507642A (ja) | 1994-10-26 | 1998-07-28 | ノボ ノルディスク アクティーゼルスカブ | 脂肪分解活性を有する酵素 |
| AR000862A1 (es) | 1995-02-03 | 1997-08-06 | Novozymes As | Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del |
| JPH08228778A (ja) | 1995-02-27 | 1996-09-10 | Showa Denko Kk | 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法 |
| DE815209T1 (de) | 1995-03-17 | 1998-06-25 | Novonordisk As | Neue endoglukanase |
| ATE282087T1 (de) | 1995-07-14 | 2004-11-15 | Novozymes As | Modifiziertes enzym mit lipolytischer aktivität |
| ATE267248T1 (de) | 1995-08-11 | 2004-06-15 | Novozymes As | Neuartige lipolytische enzyme |
| US5763385A (en) | 1996-05-14 | 1998-06-09 | Genencor International, Inc. | Modified α-amylases having altered calcium binding properties |
| WO1998008940A1 (en) | 1996-08-26 | 1998-03-05 | Novo Nordisk A/S | A novel endoglucanase |
| CN101085985B (zh) | 1996-09-17 | 2012-05-16 | 诺沃奇梅兹有限公司 | 纤维素酶变体 |
| WO1998015257A1 (en) | 1996-10-08 | 1998-04-16 | Novo Nordisk A/S | Diaminobenzoic acid derivatives as dye precursors |
| EP2278001B1 (en) | 1996-11-04 | 2013-10-23 | Novozymes A/S | Protease variants and compositions |
| KR100591553B1 (ko) | 1996-11-04 | 2006-06-19 | 노보자임스 에이/에스 | 섭틸라제 변종과 조성물 |
| US6159731A (en) | 1997-02-12 | 2000-12-12 | Massachusetts Institute Of Technology | Daxx, a Fas-binding protein that activates JNK and apoptosis |
| EP1002061A1 (en) | 1997-07-04 | 2000-05-24 | Novo Nordisk A/S | FAMILY 6 ENDO-1,4-$g(b)-GLUCANASE VARIANTS AND CLEANING COMPOSIT IONS CONTAINING THEM |
| JP5043254B2 (ja) | 1998-10-26 | 2012-10-10 | ノボザイムス アクティーゼルスカブ | 糸状面細胞内の問題のdnaライブラリーの作製及びスクリーニング |
| WO2000056900A2 (en) | 1999-03-22 | 2000-09-28 | Novo Nordisk Biotech, Inc. | Promoter sequences derived from fusarium venenatum and uses thereof |
| DE10332065A1 (de) | 2003-07-11 | 2005-01-27 | Friedrich-Schiller-Universität Jena | Verfahren zur enzymatischen Darstellung von Säuren aus Alkoholen über die intermediäre Bildung von Aldehyden |
| ES2332592T3 (es) | 2003-10-30 | 2010-02-09 | Novozymes A/S | Modulos de union a carbohidratos. |
| DE102004047774A1 (de) | 2004-09-28 | 2006-03-30 | Jenabios Gmbh | Verfahren zur enzymatischen Hydroxylierung nicht-aktivierter Kohlenwasserstoffe |
| WO2008016709A2 (en) * | 2006-08-04 | 2008-02-07 | California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
-
2007
- 2007-03-30 DE DE102007016139A patent/DE102007016139A1/de not_active Withdrawn
-
2008
- 2008-03-31 AT AT08718350T patent/ATE548449T1/de active
- 2008-03-31 CA CA2682451A patent/CA2682451C/en not_active Expired - Fee Related
- 2008-03-31 CN CN200880017970.5A patent/CN101802180B/zh not_active Expired - Fee Related
- 2008-03-31 US US12/532,870 patent/US8367387B2/en not_active Expired - Fee Related
- 2008-03-31 EP EP08718350A patent/EP2158313B1/en not_active Not-in-force
- 2008-03-31 WO PCT/EP2008/053798 patent/WO2008119780A2/en not_active Ceased
- 2008-03-31 JP JP2010500298A patent/JP5411121B2/ja not_active Expired - Fee Related
- 2008-03-31 EP EP12158017.9A patent/EP2468852B1/en not_active Not-in-force
- 2008-03-31 EP EP12161074A patent/EP2471911A3/en not_active Withdrawn
- 2008-03-31 DK DK08718350.5T patent/DK2158313T3/da active
-
2012
- 2012-12-20 US US13/722,019 patent/US20130115662A1/en not_active Abandoned
-
2013
- 2013-08-21 JP JP2013171739A patent/JP2014000086A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20130115662A1 (en) | 2013-05-09 |
| EP2468852B1 (en) | 2014-07-16 |
| DE102007016139A1 (de) | 2008-10-02 |
| US8367387B2 (en) | 2013-02-05 |
| JP2014000086A (ja) | 2014-01-09 |
| JP5411121B2 (ja) | 2014-02-12 |
| CA2682451C (en) | 2015-11-24 |
| JP2010523079A (ja) | 2010-07-15 |
| ATE548449T1 (de) | 2012-03-15 |
| EP2471911A2 (en) | 2012-07-04 |
| CN101802180A (zh) | 2010-08-11 |
| EP2158313A2 (en) | 2010-03-03 |
| EP2468852A1 (en) | 2012-06-27 |
| CN101802180B (zh) | 2017-04-05 |
| EP2471911A3 (en) | 2012-12-12 |
| US20100279366A1 (en) | 2010-11-04 |
| CA2682451A1 (en) | 2008-10-09 |
| WO2008119780A3 (en) | 2009-03-12 |
| WO2008119780A2 (en) | 2008-10-09 |
| EP2158313B1 (en) | 2012-03-07 |
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