DK2137141T3 - Biphenyl-4-YL-SULFONSYREARYLAMIDER and their use as therapeutic agents - Google Patents
Biphenyl-4-YL-SULFONSYREARYLAMIDER and their use as therapeutic agents Download PDFInfo
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- DK2137141T3 DK2137141T3 DK08718826.4T DK08718826T DK2137141T3 DK 2137141 T3 DK2137141 T3 DK 2137141T3 DK 08718826 T DK08718826 T DK 08718826T DK 2137141 T3 DK2137141 T3 DK 2137141T3
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Classifications
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
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- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0705400.0A GB0705400D0 (en) | 2007-03-21 | 2007-03-21 | Therapeutic compounds andm their use |
| PCT/GB2008/000989 WO2008114022A1 (en) | 2007-03-21 | 2008-03-20 | Biphenyl-4-yl-sulfonic acid arylamides and their use as therapeutic agents |
Publications (1)
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| DK2137141T3 true DK2137141T3 (en) | 2016-02-29 |
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Family Applications (1)
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| EP (1) | EP2137141B1 (enExample) |
| JP (1) | JP5450105B2 (enExample) |
| CA (1) | CA2681320C (enExample) |
| DK (1) | DK2137141T3 (enExample) |
| ES (1) | ES2561163T3 (enExample) |
| GB (1) | GB0705400D0 (enExample) |
| HR (1) | HRP20160183T1 (enExample) |
| HU (1) | HUE028656T2 (enExample) |
| SI (1) | SI2137141T1 (enExample) |
| WO (1) | WO2008114022A1 (enExample) |
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| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| GB0817208D0 (en) * | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| WO2012035171A2 (en) * | 2010-09-17 | 2012-03-22 | Kancera Ab | New compounds |
| US9422224B2 (en) | 2011-06-13 | 2016-08-23 | Ergon Pharmaceuticals Llc | Methods of treatment using a BCAT1 inhibitor |
| US10941109B2 (en) | 2011-06-13 | 2021-03-09 | Ergon Pharmaceuticals Llc | Compositions and methods of treatment using a BCAT1 inhibitor |
| US9708276B2 (en) | 2011-10-12 | 2017-07-18 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer |
| ES2649116T3 (es) * | 2011-12-22 | 2018-01-10 | Kancera Ab | Bisarilsulfonamidas útiles en el tratamiento de inflamación y cáncer |
| BR112015007862A2 (pt) * | 2012-12-10 | 2017-07-04 | Hoffmann La Roche | derivados benzil sulfonamida como moduladores rorc |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| CA2924527C (en) | 2013-09-20 | 2022-07-12 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Compounds for treating prostate cancer |
| US20160257657A1 (en) | 2013-09-20 | 2016-09-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer |
| HUE057569T2 (hu) | 2014-12-17 | 2022-05-28 | Pimco 2664 Ltd | N-(4-hidroxi-4-metil-ciklohexil)-4-fenil-benzolszulfonamid és N-(4-hidroxi-4-metil-ciklohexil)-4-(2-piridil)-benzolszulfonamid vegyületek és terápiás alkalmazásuk |
| US10980806B2 (en) | 2016-03-24 | 2021-04-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer |
| EP3580571B1 (en) | 2017-02-07 | 2023-06-07 | Lyfstone B.V. | Biomarkers for diagnosing implant related risk of implant revision due to aseptic loosening |
| WO2020097408A1 (en) * | 2018-11-09 | 2020-05-14 | Nimbus Artemis, Inc. | Acly inhibitors and uses thereof |
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| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
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- 2007-03-21 GB GBGB0705400.0A patent/GB0705400D0/en not_active Ceased
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- 2008-03-20 HU HUE08718826A patent/HUE028656T2/en unknown
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- 2008-03-20 HR HRP20160183T patent/HRP20160183T1/hr unknown
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- 2008-03-20 EP EP08718826.4A patent/EP2137141B1/en active Active
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- 2008-03-20 ES ES08718826.4T patent/ES2561163T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2137141A1 (en) | 2009-12-30 |
| US20100286266A1 (en) | 2010-11-11 |
| ES2561163T3 (es) | 2016-02-24 |
| EP2137141B1 (en) | 2015-12-02 |
| WO2008114022A1 (en) | 2008-09-25 |
| CA2681320A1 (en) | 2008-09-25 |
| CA2681320C (en) | 2015-05-19 |
| US8524778B2 (en) | 2013-09-03 |
| GB0705400D0 (en) | 2007-05-02 |
| HRP20160183T1 (hr) | 2016-03-25 |
| HUE028656T2 (en) | 2016-12-28 |
| JP5450105B2 (ja) | 2014-03-26 |
| SI2137141T1 (sl) | 2016-03-31 |
| JP2010522152A (ja) | 2010-07-01 |
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