HUE028656T2 - Biphenyl-4-ylsulfonic acid arylamides and their use as therapeutic agents - Google Patents
Biphenyl-4-ylsulfonic acid arylamides and their use as therapeutic agents Download PDFInfo
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- HUE028656T2 HUE028656T2 HUE08718826A HUE08718826A HUE028656T2 HU E028656 T2 HUE028656 T2 HU E028656T2 HU E08718826 A HUE08718826 A HU E08718826A HU E08718826 A HUE08718826 A HU E08718826A HU E028656 T2 HUE028656 T2 HU E028656T2
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Landscapes
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- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
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- Obesity (AREA)
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- Urology & Nephrology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0705400.0A GB0705400D0 (en) | 2007-03-21 | 2007-03-21 | Therapeutic compounds andm their use |
Publications (1)
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| HUE028656T2 true HUE028656T2 (en) | 2016-12-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| HUE08718826A HUE028656T2 (en) | 2007-03-21 | 2008-03-20 | Biphenyl-4-ylsulfonic acid arylamides and their use as therapeutic agents |
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| EP (1) | EP2137141B1 (enExample) |
| JP (1) | JP5450105B2 (enExample) |
| CA (1) | CA2681320C (enExample) |
| DK (1) | DK2137141T3 (enExample) |
| ES (1) | ES2561163T3 (enExample) |
| GB (1) | GB0705400D0 (enExample) |
| HR (1) | HRP20160183T1 (enExample) |
| HU (1) | HUE028656T2 (enExample) |
| SI (1) | SI2137141T1 (enExample) |
| WO (1) | WO2008114022A1 (enExample) |
Families Citing this family (16)
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| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB0817208D0 (en) * | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| EP2616450B1 (en) | 2010-09-17 | 2018-05-02 | Kancera AB | Sulfonamide compounds |
| US9422224B2 (en) | 2011-06-13 | 2016-08-23 | Ergon Pharmaceuticals Llc | Methods of treatment using a BCAT1 inhibitor |
| US10941109B2 (en) | 2011-06-13 | 2021-03-09 | Ergon Pharmaceuticals Llc | Compositions and methods of treatment using a BCAT1 inhibitor |
| US9708276B2 (en) | 2011-10-12 | 2017-07-18 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer |
| WO2013093095A1 (en) * | 2011-12-22 | 2013-06-27 | Kancera Ab | Bisarylsulfonamides useful in the treatment of inflammation and cancer |
| MX2015006844A (es) * | 2012-12-10 | 2015-09-16 | Hoffmann La Roche | Derivados de bencilsulfonamida como moduladores del receptor huerfano relacionado al receptor de retinoide (rorc). |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| WO2015042297A1 (en) | 2013-09-20 | 2015-03-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Compounds for treating prostate can cancer |
| US20160257657A1 (en) | 2013-09-20 | 2016-09-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer |
| ES2899852T3 (es) | 2014-12-17 | 2022-03-15 | Pimco 2664 Ltd | Compuestos de N-(4-hidroxi-4-metil-ciclohexil)-4-fenil-bencenosulfonamida y N-(-4-hidroxi-4-metil-ciclohexil)-4-(2-piridil)-bencenosulfonamida y su uso terapéutico |
| US10980806B2 (en) | 2016-03-24 | 2021-04-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer |
| PL3580571T3 (pl) | 2017-02-07 | 2023-07-31 | Lyfstone B.V. | Biomarkery do diagnozowania ryzyka rewizji implantu dotyczącego implantu z powodu obluzowania aseptycznego |
| WO2020097408A1 (en) * | 2018-11-09 | 2020-05-14 | Nimbus Artemis, Inc. | Acly inhibitors and uses thereof |
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| DE59802394D1 (de) | 1997-05-09 | 2002-01-24 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
| DE19719621A1 (de) * | 1997-05-09 | 1998-11-12 | Hoechst Ag | Sulfonylaminocarbonsäuren |
| US6291425B1 (en) | 1999-09-01 | 2001-09-18 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| CN1177832C (zh) | 1998-01-23 | 2004-12-01 | 艾文蒂斯药品德国股份有限公司 | 作为骨重吸收抑制剂和作为细胞粘附抑制剂的新的磺酰胺衍生物 |
| TR200002224T2 (tr) | 1998-02-04 | 2000-12-21 | Novartis Ag | Matris-bozucu metalloproteinasları inhibe eden sülfonilamino türevleri. |
| JPH11246527A (ja) | 1998-03-02 | 1999-09-14 | Shionogi & Co Ltd | Ｍｍｐ−８阻害剤 |
| EP0960882A1 (en) | 1998-05-19 | 1999-12-01 | Hoechst Marion Roussel Deutschland GmbH | Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists |
| PL357277A1 (en) * | 2000-03-21 | 2004-07-26 | The Procter & Gamble Company | Carbocyclic side chain containing, n-substituted metalloprotease inhibitors |
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| GB0126157D0 (en) | 2001-10-31 | 2002-01-02 | Univ Aberdeen | Therapeutic compounds |
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| DK1537116T3 (da) | 2002-09-04 | 2010-09-27 | Schering Corp | Pyrazolopyrimidiner egnede til behandling af cancersygdomme |
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| DK1638544T3 (da) * | 2003-05-07 | 2008-03-31 | Univ Aberdeen | Ketoner og reducerede ketoner som terapeutiske midler til behandling af knogletilstande |
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| OA13344A (en) | 2003-12-19 | 2007-04-13 | Pfizer | Benzenesulfonylamino-pyridin-2-yl derivatives and related compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) for the treatment of diabetes and obesity. |
| EP1723132A1 (en) | 2004-02-12 | 2006-11-22 | Asterand Uk Limited | Ep2 receptor agonists |
| GB0405193D0 (en) | 2004-03-08 | 2004-04-21 | Medical Res Council | Compounds |
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| EP1659113A1 (en) | 2004-11-08 | 2006-05-24 | Evotec AG | Inhibitors of 11beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1) |
| ATE449094T1 (de) | 2005-06-16 | 2009-12-15 | Pfizer | N-(pyridin-2-yl)sulfonamidderivate |
| WO2007008541A2 (en) | 2005-07-08 | 2007-01-18 | Kalypsys, Inc. | Cellular cholesterol absorption modifiers |
| TW200720261A (en) * | 2005-08-31 | 2007-06-01 | Sankyo Co | Phenylene derivatives |
| CN103265495B (zh) * | 2005-12-29 | 2016-11-16 | 莱西肯医药有限公司 | 多环氨基酸衍生物及其使用方法 |
| US7560597B2 (en) * | 2007-03-08 | 2009-07-14 | The University Court Of The University Of Aberdeen | 2′,4′-dichloro-biphenyl-4-yl-hydroxy-ketones and related compounds and their use as therapeutic agents |
| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB0817208D0 (en) * | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
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- 2007-03-21 GB GBGB0705400.0A patent/GB0705400D0/en not_active Ceased
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2008
- 2008-03-20 SI SI200831582T patent/SI2137141T1/sl unknown
- 2008-03-20 CA CA2681320A patent/CA2681320C/en active Active
- 2008-03-20 US US12/531,732 patent/US8524778B2/en active Active
- 2008-03-20 HU HUE08718826A patent/HUE028656T2/en unknown
- 2008-03-20 WO PCT/GB2008/000989 patent/WO2008114022A1/en not_active Ceased
- 2008-03-20 EP EP08718826.4A patent/EP2137141B1/en active Active
- 2008-03-20 DK DK08718826.4T patent/DK2137141T3/en active
- 2008-03-20 JP JP2009554083A patent/JP5450105B2/ja active Active
- 2008-03-20 HR HRP20160183T patent/HRP20160183T1/hr unknown
- 2008-03-20 ES ES08718826.4T patent/ES2561163T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| GB0705400D0 (en) | 2007-05-02 |
| HRP20160183T1 (hr) | 2016-03-25 |
| JP5450105B2 (ja) | 2014-03-26 |
| SI2137141T1 (sl) | 2016-03-31 |
| EP2137141A1 (en) | 2009-12-30 |
| US8524778B2 (en) | 2013-09-03 |
| EP2137141B1 (en) | 2015-12-02 |
| JP2010522152A (ja) | 2010-07-01 |
| ES2561163T3 (es) | 2016-02-24 |
| US20100286266A1 (en) | 2010-11-11 |
| DK2137141T3 (en) | 2016-02-29 |
| CA2681320A1 (en) | 2008-09-25 |
| WO2008114022A1 (en) | 2008-09-25 |
| CA2681320C (en) | 2015-05-19 |
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