DK2090582T3 - Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner - Google Patents

Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner

Info

Publication number
DK2090582T3
DK2090582T3 DK09155033.5T DK09155033T DK2090582T3 DK 2090582 T3 DK2090582 T3 DK 2090582T3 DK 09155033 T DK09155033 T DK 09155033T DK 2090582 T3 DK2090582 T3 DK 2090582T3
Authority
DK
Denmark
Prior art keywords
factor viii
proteins
binding molecules
human factor
human
Prior art date
Application number
DK09155033.5T
Other languages
Danish (da)
English (en)
Inventor
Jinan Yu
Daniel M Potter
Brian D Kelley
Jeffrey S Deetz
James E Booth
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Application granted granted Critical
Publication of DK2090582T3 publication Critical patent/DK2090582T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
DK09155033.5T 1999-01-04 2000-01-03 Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner DK2090582T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII
EP06009040A EP1705183B1 (en) 1999-01-04 2000-01-03 Binding molecules for human factor VIII and factor VIII-like proteins

Publications (1)

Publication Number Publication Date
DK2090582T3 true DK2090582T3 (da) 2012-10-15

Family

ID=22842198

Family Applications (4)

Application Number Title Priority Date Filing Date
DK09155033.5T DK2090582T3 (da) 1999-01-04 2000-01-03 Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner
DK06009040T DK1705183T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner
DK10182747.5T DK2301953T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler til human faktor VIII og faktor VIII-lignende proteiner
DK10182741.8T DK2298791T3 (en) 1999-01-04 2000-01-03 Binding molecules for human factor VIII and factor VIII-like proteins

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK06009040T DK1705183T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner
DK10182747.5T DK2301953T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler til human faktor VIII og faktor VIII-lignende proteiner
DK10182741.8T DK2298791T3 (en) 1999-01-04 2000-01-03 Binding molecules for human factor VIII and factor VIII-like proteins

Country Status (12)

Country Link
US (2) US6197526B1 (cg-RX-API-DMAC7.html)
EP (5) EP2298791B8 (cg-RX-API-DMAC7.html)
JP (3) JP4733272B2 (cg-RX-API-DMAC7.html)
AT (1) ATE433992T1 (cg-RX-API-DMAC7.html)
AU (3) AU769745B2 (cg-RX-API-DMAC7.html)
CA (1) CA2354599C (cg-RX-API-DMAC7.html)
DE (1) DE60042430D1 (cg-RX-API-DMAC7.html)
DK (4) DK2090582T3 (cg-RX-API-DMAC7.html)
ES (4) ES2390360T3 (cg-RX-API-DMAC7.html)
HK (1) HK1038756A1 (cg-RX-API-DMAC7.html)
PT (3) PT2298791E (cg-RX-API-DMAC7.html)
WO (1) WO2000040602A1 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) * 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
AU2003230509B2 (en) * 2002-04-29 2009-03-12 Affibody Ab Sandwich assay and kit
WO2007065691A2 (en) * 2005-12-07 2007-06-14 Technische Universität München Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) * 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
EP2156179B1 (en) 2007-04-04 2021-08-18 The Regents of The University of California Methods for using a nanopore
EA201070231A1 (ru) 2007-08-09 2010-10-29 Синтоникс Фармасьютикалз, Инк. Иммуномодулирующие пептиды
AR071478A1 (es) 2008-04-17 2010-06-23 Baxter Healthcare Sa Peptidos de bajo peso molecular con actividad procoagulante para el tratamiento de pacientes con deficiencia de factor v (fv), fvii, fviii, fx y/o fxi
US20100048488A1 (en) * 2008-08-01 2010-02-25 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
EP3527218A1 (en) * 2011-06-10 2019-08-21 Bioverativ Therapeutics Inc. Pro-coagulant compounds and methods of use thereof
JP6702866B2 (ja) 2013-11-18 2020-06-03 ルビウス セラピューティクス, インコーポレイテッド 合成膜−レシーバー複合体
CN116731197A (zh) * 2016-09-19 2023-09-12 豪夫迈·罗氏有限公司 基于补体因子的亲和层析
SG11202000979SA (en) 2017-08-04 2020-02-27 Shire Human Genetic Therapies Antibody-resin coupling apparatus and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
EP0218712B1 (en) 1985-04-12 1992-02-26 Genetics Institute, Inc. Novel procoagulant proteins
DE68927933T2 (de) * 1988-09-02 1997-08-14 Dyax Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
AU1757592A (en) * 1991-03-27 1992-11-02 Scripps Research Institute, The Therapeutic fragments of von willebrand factor
AU713744B2 (en) * 1996-03-20 1999-12-09 Dyax Corp. Engineering affinity ligands for macromolecules
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
KR20000016414A (ko) 1996-06-06 2000-03-25 와이즈먼 앤드루 Apl 면역반응성 펩티드, 그것의 콘주게이트 및 apl항체-매개병변의 치료방법
EP1095143B1 (en) * 1998-05-08 2008-08-20 Stichting Sanquin Bloedvoorziening Inhibitor for diagnosis and treatment of haemophilia a patients
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
DE60042430D1 (de) 2009-07-30
HK1155756A1 (en) 2012-05-25
JP2010254694A (ja) 2010-11-11
HK1131398A1 (en) 2010-01-22
ES2524965T3 (es) 2014-12-16
AU769745B2 (en) 2004-02-05
EP1705183A1 (en) 2006-09-27
EP2090582B1 (en) 2012-09-19
DK1705183T3 (da) 2009-10-19
JP4733272B2 (ja) 2011-07-27
CA2354599C (en) 2013-03-12
ES2390360T3 (es) 2012-11-12
AU2598200A (en) 2000-07-24
AU2004201830B2 (en) 2007-04-05
ES2328722T3 (es) 2009-11-17
EP2301953B1 (en) 2014-07-30
JP2013079272A (ja) 2013-05-02
JP5572207B2 (ja) 2014-08-13
HK1155182A1 (en) 2012-05-11
US20010014456A1 (en) 2001-08-16
JP2002536297A (ja) 2002-10-29
EP2298791B8 (en) 2014-12-24
AU2004201830A1 (en) 2004-05-27
EP2298791B1 (en) 2014-11-12
AU2004201810A1 (en) 2004-05-27
EP2301953A1 (en) 2011-03-30
EP1147128A4 (en) 2004-10-13
ES2499040T3 (es) 2014-09-26
PT1705183E (pt) 2009-07-31
EP1147128A1 (en) 2001-10-24
PT2301953E (pt) 2014-09-15
PT2298791E (pt) 2014-12-16
EP2090582A2 (en) 2009-08-19
WO2000040602A1 (en) 2000-07-13
EP1705183B1 (en) 2009-06-17
ATE433992T1 (de) 2009-07-15
EP2298791A1 (en) 2011-03-23
JP5368371B2 (ja) 2013-12-18
DK2298791T3 (en) 2014-12-08
HK1038756A1 (zh) 2002-03-28
EP2090582A3 (en) 2009-11-11
US6492105B2 (en) 2002-12-10
US6197526B1 (en) 2001-03-06
DK2301953T3 (da) 2014-09-22
CA2354599A1 (en) 2000-07-13

Similar Documents

Publication Publication Date Title
DK2090582T3 (da) Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner
EP1674477A3 (en) Binding polypeptides for B lymphocyte stimulator protein (BLYS)
WO2002032925A3 (en) Protein scaffolds for antibody mimics and other binding proteins
WO2001004265A3 (en) C-terminal protein tagging
ATE555206T1 (de) Dns-konstrukte zur expression von heterologen polypeptide in pflanzen
HUT77049A (hu) Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok
WO2004061080A3 (en) Stress-related polypeptides and uses therefor
WO2005047459A3 (en) Sars nucleic acids, proteins, antibodies, and uses thereof
IL147527A0 (en) Conjugates and methods for the production thereof, and their use for transporting molecules via biological membranes
EP1243923A4 (en) METHOD FOR SELECTING A CANCER REMEDY USING P53 AND MORTALIN INTERACTION AREAS
ZA975588B (en) Isolated nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof.
ATE223491T1 (de) Verfahren zur reinigung von biomolekül- oder proteinkomplexen
ZA9710163B (en) Novel carboxylesterase nucleic acid molecules, proteins and uses thereof.
IL169804A (en) 254p1d6b proteins, nucleic acids encoding the same, processes for producing the same, antibodies binding thereto and uses thereof
WO2001029220A3 (en) Mage-a12 antigenic peptides and uses thereof
AU1174402A (en) Nucleic acid molecules and polypeptides for immune modulation
WO2001021794A3 (en) Smad associating polypeptides
WO2000057188A3 (fr) Proteines associees a un cancer mammaire et procede de detection de ces proteines
DE60136643D1 (de) Neuromedin u delta polypeptide
WO2001028580A3 (en) Modulation of angiogenesis
WO2001034803A3 (en) Crib protein zmse1
WO2003002611A3 (de) Fusionsproteine, verfahren zu deren herstellung und deren verwendung