DK2053063T3 - Genkendelsesmolekyler til behandling og påvisning af tumorer - Google Patents

Genkendelsesmolekyler til behandling og påvisning af tumorer

Info

Publication number
DK2053063T3
DK2053063T3 DK08171923.9T DK08171923T DK2053063T3 DK 2053063 T3 DK2053063 T3 DK 2053063T3 DK 08171923 T DK08171923 T DK 08171923T DK 2053063 T3 DK2053063 T3 DK 2053063T3
Authority
DK
Denmark
Prior art keywords
tyr
asn
gly
ala
sequences
Prior art date
Application number
DK08171923.9T
Other languages
English (en)
Inventor
Steffen Goletz
Antje Danielczyk
Renate Stahn
Uwe Karsten
Original Assignee
Glycotope Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycotope Gmbh filed Critical Glycotope Gmbh
Application granted granted Critical
Publication of DK2053063T3 publication Critical patent/DK2053063T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Finger-Pressure Massage (AREA)
DK08171923.9T 2003-01-23 2004-01-23 Genkendelsesmolekyler til behandling og påvisning af tumorer DK2053063T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10303664A DE10303664A1 (de) 2003-01-23 2003-01-23 Erkennungsmoleküle zur Behandlung und Detektion von Tumoren
EP04704545A EP1585770B1 (de) 2003-01-23 2004-01-23 Erkennungsmoleküle zur behandlung und detektion von tumoren

Publications (1)

Publication Number Publication Date
DK2053063T3 true DK2053063T3 (da) 2013-09-30

Family

ID=32695061

Family Applications (2)

Application Number Title Priority Date Filing Date
DK08171923.9T DK2053063T3 (da) 2003-01-23 2004-01-23 Genkendelsesmolekyler til behandling og påvisning af tumorer
DK04704545T DK1585770T3 (da) 2003-01-23 2004-01-23 Genkendelsesmolekyler til behandling og påvisning af tumorer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK04704545T DK1585770T3 (da) 2003-01-23 2004-01-23 Genkendelsesmolekyler til behandling og påvisning af tumorer

Country Status (10)

Country Link
US (2) US8779102B2 (da)
EP (2) EP2053063B1 (da)
AT (1) ATE421537T1 (da)
CY (2) CY1108965T1 (da)
DE (2) DE10303664A1 (da)
DK (2) DK2053063T3 (da)
ES (2) ES2427832T3 (da)
PT (2) PT1585770E (da)
SI (2) SI2053063T1 (da)
WO (1) WO2004065423A2 (da)

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DE10256900A1 (de) 2002-11-29 2004-06-24 Nemod Immuntherapie Ag Tumorspezifische Erkennungsmoleküle
US7960512B2 (en) 2003-01-09 2011-06-14 Macrogenics, Inc. Identification and engineering of antibodies with variant Fc regions and methods of using same
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US11254748B2 (en) 2005-04-15 2022-02-22 Macrogenics, Inc. Covalent diabodies and uses thereof
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Also Published As

Publication number Publication date
PT2053063E (pt) 2013-09-24
SI2053063T1 (sl) 2013-10-30
ES2321298T3 (es) 2009-06-04
WO2004065423A3 (de) 2004-11-25
WO2004065423A2 (de) 2004-08-05
EP2053063A1 (de) 2009-04-29
US9845361B2 (en) 2017-12-19
PT1585770E (pt) 2009-03-18
SI1585770T1 (sl) 2009-06-30
CY1108965T1 (el) 2014-07-02
ES2427832T3 (es) 2013-11-04
US20150005474A1 (en) 2015-01-01
DK1585770T3 (da) 2009-05-04
US8779102B2 (en) 2014-07-15
EP1585770A2 (de) 2005-10-19
DE502004008910D1 (de) 2009-03-12
DE10303664A1 (de) 2004-08-12
CY1114409T1 (el) 2016-08-31
ATE421537T1 (de) 2009-02-15
EP1585770B1 (de) 2009-01-21
US20060292643A1 (en) 2006-12-28
EP2053063B1 (de) 2013-06-19

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