CY1110308T1 - Μοριο νουκλεϊνικου οξεος, το οποιο περιλαμβανει μια κωδικευσουσα για αιμοκυανινη ακολουθια νουκλεϊνικου οξεος και τουλαχιστον μια ακολουθια ιντρονιου - Google Patents
Μοριο νουκλεϊνικου οξεος, το οποιο περιλαμβανει μια κωδικευσουσα για αιμοκυανινη ακολουθια νουκλεϊνικου οξεος και τουλαχιστον μια ακολουθια ιντρονιουInfo
- Publication number
- CY1110308T1 CY1110308T1 CY20091100015T CY091100015T CY1110308T1 CY 1110308 T1 CY1110308 T1 CY 1110308T1 CY 20091100015 T CY20091100015 T CY 20091100015T CY 091100015 T CY091100015 T CY 091100015T CY 1110308 T1 CY1110308 T1 CY 1110308T1
- Authority
- CY
- Cyprus
- Prior art keywords
- nucleic acid
- sequence
- construct
- immunocyanic
- tuberculosis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
- C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
- C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
- C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
- C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
Abstract
Η παρούσα εφεύρεση αφορά ένα μόριο νουκλεϊνικού οξέος, το οποίο περιλαμβάνει μια κωδικεύουσα για μια αιμοκυανίνη, μια περιοχή αιμοκυανίνης ή ένα θραύσμα με τις ανοσολογικές ιδιότητες τουλάχιστον μιας περιοχής αιμοκυανίνης ακολουθία νουκλεϊνικού οξέος και τουλάχιστον μια ακολουθία ιντρονίου. Η παρούσα εφεύρεση αφορά ακόμη κατασκευάσματα, τα οποία περιέχουν το μόριο νουκλεϊνικού οξέος και ενδεχομένως έναν κατάλληλο για τον έλεγχο έκφρασης πριμοδότη. Σε μια προτιμητέα μορφή διεξαγωγής το κατασκεύασμα περιέχει ακόμη μια κωδικεύουσα για ένα αντιγόνο ακολουθία νουκλεϊνικού οξέος. Η εφεύρεση αφορά ακόμη κύτταρα ξενιστές, τα οποία περιέχουν τα μόρια αυτά νουκλεϊνικού οξέος και/ή τα κατασκευάσματα. Η εφεύρεση αφορά ακόμη την ανασυνδυασμένη έκφραση των μορίων νουκλεϊνικού οξέος και/ή των κατασκευασμάτων στα κύτταρα ξενιστές. Η εφεύρεση αφορά ακόμη αιμοκυανίνη, μια περιοχή αιμοκυανίνης, ένα θραύσμα με τις ανοσολογικές ιδιότητες τουλάχιστον μιας περιοχής αιμοκυανίνης και συγχωνευμένες πρωτεϊνες αιμοκυανίνης, οι οποίες κωδικεύονται από τα μόρια νουκλεϊνικού οξέος και/ή τα κατασκευάσματα. Η εφεύρεση αφορά ακόμη φαρμακευτικές συνθέσεις, οι οποίες περιέχουν τα μόρια νουκλεϊνικού οξέος και/ή αιμοκυανίνη, μια περιοχή αιμοκυανίνης, ένα θραύσμα της ή μια συγχωνευμένη πρωτεΐνη. Η εφεύρεση αφορά ακόμη λιποσώματα, τα οποία περιέχουν τα μόρια νουκλεϊνικού οξέος και/ή αιμοκυανίνη, μια περιοχή αιμοκυανίνης, ένα θραύσμα της ή μια συγχωνευμένη πρωτεΐνη. Η εφεύρεση αφορά ακόμη αντισώματα, τα οποία λαμβάνονται με ανοσοποίηση ενός πειραματόζωου με την αιμοκυανίνη, μια περιοχή αιμοκυανίνης, ένα θραύσμα της ή μια συγχωνευμένη πρωτεΐνη, και τη
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19939578A DE19939578A1 (de) | 1999-08-20 | 1999-08-20 | Nukleinsäuremolekül, umfassend eine für ein Hämocyanin kodierende Nukleinsäuresequenz |
| EP00956469A EP1233980B1 (de) | 1999-08-20 | 2000-08-21 | Nukleinsäuremolekül, umfassend eine für ein hämocyanin kodierende nukleinsäuresequenz und mindestens eine intronsequenz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1110308T1 true CY1110308T1 (el) | 2015-01-14 |
Family
ID=7919075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100015T CY1110308T1 (el) | 1999-08-20 | 2009-01-09 | Μοριο νουκλεϊνικου οξεος, το οποιο περιλαμβανει μια κωδικευσουσα για αιμοκυανινη ακολουθια νουκλεϊνικου οξεος και τουλαχιστον μια ακολουθια ιντρονιου |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7125557B1 (el) |
| EP (1) | EP1233980B1 (el) |
| AT (1) | ATE411338T1 (el) |
| AU (1) | AU6839900A (el) |
| CA (1) | CA2376346C (el) |
| CY (1) | CY1110308T1 (el) |
| DE (2) | DE19939578A1 (el) |
| DK (1) | DK1233980T3 (el) |
| ES (1) | ES2315239T3 (el) |
| PT (1) | PT1233980E (el) |
| WO (1) | WO2001014536A2 (el) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003023006A2 (en) * | 2001-09-06 | 2003-03-20 | Pierce Biotechnology, Inc. | Hemocyanin nucleic acids and polypeptides and related vectors, fusion proteins, conjugates, cells and methods of use |
| CN102719440B (zh) * | 2012-06-01 | 2013-07-03 | 中国水产科学研究院南海水产研究所 | 杂色鲍血蓝蛋白ⅰ和ⅱ型亚基基因及克隆方法 |
| CN108998427B (zh) * | 2018-07-27 | 2021-07-06 | 广东海洋大学 | 一种酚氧化酶活性蛋白的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2598147B1 (fr) | 1986-04-30 | 1988-08-26 | Pasteur Institut | Immunogene isole de mollusques, son procede de preparation, reactifs de diagnostic des bilharzioses humaines, vaccins contre les schistosomiases et compositions immunisantes comprenant ledit immunogene. |
| FR2601021B2 (fr) | 1986-07-07 | 1988-11-18 | Pasteur Institut | Fraction immunogene active a l'egard des bilharzioses, sa preparation, compositions immunisantes la contenant |
| AU675269B2 (en) * | 1992-11-09 | 1997-01-30 | Zonagen, Inc. | Materials and methods for immunocontraception |
| US5407912A (en) | 1993-04-19 | 1995-04-18 | Akzo, N.V. | Method of treating bladder cancer with a keyhole limpet hemocyanin composition with enhanced anti-tumor activity |
| US5888775A (en) | 1994-04-29 | 1999-03-30 | Dade International Inc | Peptide synthesis and purification by fusion to penI protein or precipitation effective portion thereof |
| US5831033A (en) | 1997-02-14 | 1998-11-03 | Children's Medical Center Of Boston | Human thymosin β15 gene, protein and uses thereof |
| CA2365451A1 (en) | 1999-03-17 | 2000-09-21 | Biosyn Arzneimittel Gmbh | Nucleic acid molecule comprising a nucleic acid sequence coding for a hemocyanin |
-
1999
- 1999-08-20 DE DE19939578A patent/DE19939578A1/de not_active Ceased
-
2000
- 2000-08-21 DK DK00956469T patent/DK1233980T3/da active
- 2000-08-21 DE DE50015410T patent/DE50015410D1/de not_active Expired - Lifetime
- 2000-08-21 ES ES00956469T patent/ES2315239T3/es not_active Expired - Lifetime
- 2000-08-21 AT AT00956469T patent/ATE411338T1/de active
- 2000-08-21 US US10/049,988 patent/US7125557B1/en not_active Expired - Lifetime
- 2000-08-21 CA CA2376346A patent/CA2376346C/en not_active Expired - Fee Related
- 2000-08-21 EP EP00956469A patent/EP1233980B1/de not_active Expired - Lifetime
- 2000-08-21 PT PT00956469T patent/PT1233980E/pt unknown
- 2000-08-21 AU AU68399/00A patent/AU6839900A/en not_active Abandoned
- 2000-08-21 WO PCT/EP2000/008129 patent/WO2001014536A2/de active Application Filing
-
2006
- 2006-08-29 US US11/512,044 patent/US7273928B2/en not_active Expired - Lifetime
-
2009
- 2009-01-09 CY CY20091100015T patent/CY1110308T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE411338T1 (de) | 2008-10-15 |
| WO2001014536A3 (de) | 2002-06-27 |
| EP1233980B1 (de) | 2008-10-15 |
| ES2315239T3 (es) | 2009-04-01 |
| CA2376346A1 (en) | 2001-03-01 |
| PT1233980E (pt) | 2009-01-28 |
| US20070154486A1 (en) | 2007-07-05 |
| DK1233980T3 (da) | 2009-02-16 |
| US7273928B2 (en) | 2007-09-25 |
| WO2001014536A2 (de) | 2001-03-01 |
| DE50015410D1 (de) | 2008-11-27 |
| US7125557B1 (en) | 2006-10-24 |
| DE19939578A1 (de) | 2001-02-22 |
| AU6839900A (en) | 2001-03-19 |
| CA2376346C (en) | 2011-07-26 |
| EP1233980A2 (de) | 2002-08-28 |
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