CY1107629T1 - Πρωτεïνη crsp (πλουσιες σε κυστεïνη εκκρινομενες πρωτεïνες) μορια νουκλεϊνικου οξεως που τις κωδικοποιουν και χρησεις τους - Google Patents

Πρωτεïνη crsp (πλουσιες σε κυστεïνη εκκρινομενες πρωτεïνες) μορια νουκλεϊνικου οξεως που τις κωδικοποιουν και χρησεις τους

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Publication number
CY1107629T1
CY1107629T1 CY20071100650T CY071100650T CY1107629T1 CY 1107629 T1 CY1107629 T1 CY 1107629T1 CY 20071100650 T CY20071100650 T CY 20071100650T CY 071100650 T CY071100650 T CY 071100650T CY 1107629 T1 CY1107629 T1 CY 1107629T1
Authority
CY
Cyprus
Prior art keywords
crsp
clear
protein
nucleic acid
proteins
Prior art date
Application number
CY20071100650T
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English (en)
Inventor
Sean A Mccarthy
Original Assignee
Millennium Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27485904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107629(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Millennium Pharmaceuticals, Inc. filed Critical Millennium Pharmaceuticals, Inc.
Publication of CY1107629T1 publication Critical patent/CY1107629T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)

Abstract

Αποκαλύπτονται πολυπεπτίδια, πρωτεΐνες και μόρια νουκλεϊνικού οξέως CRSP (πλούσιες σε κυστεΐνη εκκρινόμενες πρωτεΐνες). Επί πλέον των απομονωμένων πρωτεϊνών πλήρους μήκους CRSP, η εφεύρεση παρέχει περαιτέρω απομονωμένες πρωτεΐνες συγχωνεύσεως CRSP, αντιγονικά πεπτίδια και αντισώματα αντι-CRSP. Η εφεύρεση παρέχει επίσης μόρια νουκλεϊνικού οξέως CRSP, ανασυνδυασμένους φορείς αποκωδικοποιήσεως περιέχοντες ένα μόριο νουκλεϊνικού οξέως της εφευρέσεως, κύτταρα ξενιστές εντός των οποίων έχουν εισαχθεί οι φορείς αποκωδικοποιήσεως και διαγονιδιακά ζώα εκτός του ανθρώπου στα οποία έχει εισαχθεί ή διαταραχθεί ένα γονίδιο CRSP. Παρέχονται επίσης μέθοδοι διαγνώσεως, διαλογής και θεραπείας οι οποίες χρησιμοποιούν συνθέσεις της εφευρέσεως.
CY20071100650T 1997-04-16 2007-05-14 Πρωτεïνη crsp (πλουσιες σε κυστεïνη εκκρινομενες πρωτεïνες) μορια νουκλεϊνικου οξεως που τις κωδικοποιουν και χρησεις τους CY1107629T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84370497A 1997-04-16 1997-04-16
US84289897A 1997-04-17 1997-04-17
US7158998P 1998-01-15 1998-01-15
US980298A 1998-01-20 1998-01-20
EP98918453A EP0975755B2 (en) 1997-04-16 1998-04-16 Crsp protein (cysteine-rich secreted proteins), nucleic acid molecules encoding them and uses therefor

Publications (1)

Publication Number Publication Date
CY1107629T1 true CY1107629T1 (el) 2013-06-19

Family

ID=27485904

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100650T CY1107629T1 (el) 1997-04-16 2007-05-14 Πρωτεïνη crsp (πλουσιες σε κυστεïνη εκκρινομενες πρωτεïνες) μορια νουκλεϊνικου οξεως που τις κωδικοποιουν και χρησεις τους

Country Status (11)

Country Link
EP (3) EP0975755B2 (el)
JP (4) JP2001524824A (el)
AT (2) ATE353964T1 (el)
AU (2) AU7137398A (el)
CA (1) CA2288430C (el)
CY (1) CY1107629T1 (el)
DE (2) DE69837085T3 (el)
DK (1) DK0975755T3 (el)
ES (1) ES2285768T5 (el)
PT (1) PT975755E (el)
WO (1) WO1998046755A1 (el)

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Publication number Publication date
JP2006166917A (ja) 2006-06-29
EP0975755B2 (en) 2011-08-03
CA2288430A1 (en) 1998-10-22
ATE353964T1 (de) 2007-03-15
ES2285768T3 (es) 2007-11-16
WO1998046755A1 (en) 1998-10-22
DK0975755T3 (da) 2007-06-11
JP2001524824A (ja) 2001-12-04
AU2009227915A1 (en) 2009-11-12
EP0975755B1 (en) 2007-02-14
EP0975755A1 (en) 2000-02-02
AU7137398A (en) 1998-11-11
EP1852507A1 (en) 2007-11-07
CA2288430C (en) 2013-04-09
DE69837085T3 (de) 2012-01-12
EP0975755B9 (en) 2007-08-29
DE69837085T2 (de) 2007-11-22
JP2010227110A (ja) 2010-10-14
EP1852507B1 (en) 2011-04-13
EP2298899A3 (en) 2011-08-24
ES2285768T5 (es) 2011-12-22
DE69842225D1 (de) 2011-05-26
PT975755E (pt) 2007-06-26
DE69837085D1 (de) 2007-03-29
JP2010011853A (ja) 2010-01-21
EP2298899A2 (en) 2011-03-23
ATE505543T1 (de) 2011-04-15

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