WO1999054437A3 - Novel molecules of the t125-related protein family and uses thereof - Google Patents

Novel molecules of the t125-related protein family and uses thereof Download PDF

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Publication number
WO1999054437A3
WO1999054437A3 PCT/US1999/008900 US9908900W WO9954437A3 WO 1999054437 A3 WO1999054437 A3 WO 1999054437A3 US 9908900 W US9908900 W US 9908900W WO 9954437 A3 WO9954437 A3 WO 9954437A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
proteins
related protein
protein family
novel molecules
Prior art date
Application number
PCT/US1999/008900
Other languages
French (fr)
Other versions
WO1999054437A2 (en
Inventor
Douglas A Holtzman
Original Assignee
Millennium Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Biotherapeutics Inc filed Critical Millennium Biotherapeutics Inc
Priority to AU39657/99A priority Critical patent/AU3965799A/en
Publication of WO1999054437A2 publication Critical patent/WO1999054437A2/en
Publication of WO1999054437A3 publication Critical patent/WO1999054437A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Novel T125 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length T125 proteins, the invention further provides isolated T125 fusion proteins, antigenic peptides and anti-T125 antibodies. The invention also provides T125 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a T125 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
PCT/US1999/008900 1998-04-23 1999-04-23 Novel molecules of the t125-related protein family and uses thereof WO1999054437A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU39657/99A AU3965799A (en) 1998-04-23 1999-04-23 Novel molecules of the t125-related protein family and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6536398A 1998-04-23 1998-04-23
US09/065,363 1998-04-23

Publications (2)

Publication Number Publication Date
WO1999054437A2 WO1999054437A2 (en) 1999-10-28
WO1999054437A3 true WO1999054437A3 (en) 1999-12-09

Family

ID=22062192

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/008900 WO1999054437A2 (en) 1998-04-23 1999-04-23 Novel molecules of the t125-related protein family and uses thereof

Country Status (2)

Country Link
AU (1) AU3965799A (en)
WO (1) WO1999054437A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053754A1 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Compositions and methods for the treatment of tumor
NZ525914A (en) * 1998-03-10 2004-03-26 Genentech Inc Novel polypeptides and nucleic acids encoding the same
US7723488B2 (en) 1998-03-27 2010-05-25 Genentech, Inc. Monoclonal antibodies to secreted and transmembrane polypeptides
PT1241186E (en) * 1998-04-22 2009-03-05 Genentech Inc Human growth arrest specific gene 6 (gas-6) and nucleic acids encoding the same
KR20030002292A (en) * 1999-03-08 2003-01-08 제넨테크, 인크. Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
FR2851249A1 (en) * 2003-02-17 2004-08-20 Commissariat Energie Atomique Using VE-statins to inhibit recruitment of perivascular smooth muscle cells, for treating e.g. cancer and retinopathy, also new VE-statins, related nucleic acids and antibodies
NZ550110A (en) 2004-04-14 2009-09-25 Genentech Inc Compositions and methods comprising an EGFL7 antagonist for modulating vascular development
MX2011010570A (en) 2009-05-08 2011-10-19 Genentech Inc Humanized anti-egfl7 antibodies and methods using same.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998057983A2 (en) * 1997-06-18 1998-12-23 Zymogenetics, Inc. Mammalian neuro-growth factor like protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998057983A2 (en) * 1997-06-18 1998-12-23 Zymogenetics, Inc. Mammalian neuro-growth factor like protein

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK ON STN, HILLIER et al., "zx07b12.rl Soares_total_fetus_Nb2HF8_9w Homo Sapiens cDNA Clone", AN AA448958, 04 June 1997. *
DATABASE STN GENBANK 1 January 1900 (1900-01-01), "QB98H07.XL SOARES FETAL NEART NBHH19W HOMO SAPIENS CDNA CLONE IMAGE91707613 3', MRNA SEQUENCE", XP002932385, Database accession no. AI146849 *

Also Published As

Publication number Publication date
WO1999054437A2 (en) 1999-10-28
AU3965799A (en) 1999-11-08

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