DK205185A - Hydrogelmaterialer med indhold af aktivt stof samt deres fremstilling og anvendelse - Google Patents

Hydrogelmaterialer med indhold af aktivt stof samt deres fremstilling og anvendelse Download PDF

Info

Publication number
DK205185A
DK205185A DK205185A DK205185A DK205185A DK 205185 A DK205185 A DK 205185A DK 205185 A DK205185 A DK 205185A DK 205185 A DK205185 A DK 205185A DK 205185 A DK205185 A DK 205185A
Authority
DK
Denmark
Prior art keywords
active agent
manufacturing
active substance
materials containing
containing active
Prior art date
Application number
DK205185A
Other languages
Danish (da)
English (en)
Other versions
DK205185D0 (da
Inventor
Ping I Lee
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK205185D0 publication Critical patent/DK205185D0/da
Publication of DK205185A publication Critical patent/DK205185A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Colloid Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DK205185A 1984-05-10 1985-05-09 Hydrogelmaterialer med indhold af aktivt stof samt deres fremstilling og anvendelse DK205185A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/608,756 US4624848A (en) 1984-05-10 1984-05-10 Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use

Publications (2)

Publication Number Publication Date
DK205185D0 DK205185D0 (da) 1985-05-09
DK205185A true DK205185A (da) 1985-11-11

Family

ID=24437841

Family Applications (1)

Application Number Title Priority Date Filing Date
DK205185A DK205185A (da) 1984-05-10 1985-05-09 Hydrogelmaterialer med indhold af aktivt stof samt deres fremstilling og anvendelse

Country Status (16)

Country Link
US (1) US4624848A (forum.php)
EP (1) EP0164311B1 (forum.php)
JP (1) JPS619A (forum.php)
AT (1) ATE61731T1 (forum.php)
AU (1) AU583507B2 (forum.php)
CA (1) CA1246447A (forum.php)
DE (1) DE3582193D1 (forum.php)
DK (1) DK205185A (forum.php)
ES (1) ES8603273A1 (forum.php)
FI (1) FI851801L (forum.php)
GR (1) GR851114B (forum.php)
IL (1) IL75129A (forum.php)
NZ (1) NZ212030A (forum.php)
PH (1) PH24100A (forum.php)
PT (1) PT80416B (forum.php)
ZA (1) ZA853511B (forum.php)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749576A (en) * 1984-05-10 1988-06-07 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
JPS61218517A (ja) * 1985-03-25 1986-09-29 Bio Materiaru Yunibaasu:Kk 経皮吸収製剤
FR2585246A1 (fr) * 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US4794002A (en) * 1985-11-01 1988-12-27 Monsanto Company Modified polymeric surfaces and process for preparing same
JPH0643851B2 (ja) * 1986-03-13 1994-06-08 大同メタル工業株式会社 軸受ユニット
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
US4780236A (en) * 1986-06-20 1988-10-25 Kiwi Brands, Inc. Lavoratory cleansing block containing polyethylene gycol disteatrate, guar gum and sodium chloride
US4743248A (en) * 1986-08-11 1988-05-10 Alza Corporation Dosage form for delivering acid sensitive beneficial agent
GB8620845D0 (en) * 1986-08-28 1986-10-08 Reckitt & Colmann Prod Ltd Treatment of textile surfaces
EP0297650A1 (en) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions with controlled zero-order delivery rate and method of preparing these compositions
US5219575A (en) * 1987-06-26 1993-06-15 Duphar International Research B.V. Compositions with controlled zero-order delivery rate and method of preparing these compositions
US4910015A (en) * 1987-10-19 1990-03-20 Massachusetts Institute Of Technology Surface-active polysiloxanes and drug releasing materials thereof
GB8801863D0 (en) * 1988-01-28 1988-02-24 Fulmer Yarsley Ltd Pharmaceutical formulations with controlled drug release
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
EP0808153B1 (en) 1995-02-10 1999-08-04 Medtronic, Inc. Method and device for administering analgesics
US5945125A (en) * 1995-02-28 1999-08-31 Temple University Controlled release tablet
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
DE19843904A1 (de) * 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit polymerem Bindemittel
DE19843903A1 (de) * 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit copolymerem Bindemittel
US6706283B1 (en) * 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
JP4100910B2 (ja) * 1999-12-23 2008-06-11 ファイザー・プロダクツ・インク ヒドロゲル駆動の薬物剤形
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
GB0027357D0 (en) * 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
MXPA03011610A (es) * 2001-07-23 2004-07-01 Alcon Inc Dispositivo para la administracion de farmacos oftalmicos.
CN1203814C (zh) 2001-07-23 2005-06-01 爱尔康公司 眼部药物输送装置
US7300668B2 (en) * 2001-10-29 2007-11-27 Massachusetts Institute Of Technology System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
GB0310636D0 (en) * 2003-05-08 2003-06-11 Nektar Therapeutics Uk Ltd Particulate materials
KR20060015587A (ko) 2003-05-08 2006-02-17 넥타 쎄라퓨틱스 유케이 리미티드 미립물
EP1684669A4 (en) * 2003-07-10 2008-01-02 Alcon Inc DEVICE FOR RELEASING AN OPHTHALMIC MEDICINAL PRODUCT
US20060246109A1 (en) * 2005-04-29 2006-11-02 Hossainy Syed F Concentration gradient profiles for control of agent release rates from polymer matrices
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
CA2949643C (en) 2005-09-27 2018-05-15 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
US8022054B2 (en) 2005-11-28 2011-09-20 Marinus Pharmaceuticals Liquid ganaxolone formulations and methods for the making and use thereof
US8246973B2 (en) 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
EP2041214A4 (en) 2006-07-10 2009-07-08 Medipacs Inc SUPERELASTIC EPOXY HYDROGEL
EP2056818B1 (en) 2006-08-11 2011-05-25 The Johns Hopkins University Compositions and methods for neuroprotection
BRPI0622054B8 (pt) 2006-09-22 2021-05-25 Oxford Amherst Llc composto e composição farmacêutica
AU2008299220B2 (en) 2007-09-10 2011-07-21 Calcimedica, Inc. Compounds that modulate intracellular calcium
JP2011505520A (ja) 2007-12-03 2011-02-24 メディパックス インコーポレイテッド 流体計量供給装置
WO2010027875A2 (en) 2008-08-27 2010-03-11 Calcimedica Inc. Compounds that modulate intracellular calcium
CA2758571A1 (en) 2009-04-24 2010-10-28 Tissuetech, Inc. Compositions containing hc-ha complex and methods of use thereof
US9238102B2 (en) 2009-09-10 2016-01-19 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US7741330B1 (en) 2009-10-12 2010-06-22 Pharmacyclics, Inc. Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
WO2011130689A1 (en) 2010-04-15 2011-10-20 Tracon Pharmaceuticals, Inc. Potentiation of anti-cancer activity through combination therapy with ber pathway inhibitors
EP2563776B1 (en) 2010-04-27 2016-06-08 Calcimedica, Inc. Compounds that modulate intracellular calcium
EP2563759B1 (en) 2010-04-27 2022-04-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
KR101580714B1 (ko) 2010-06-03 2016-01-04 파마싸이클릭스 엘엘씨 브루톤 티로신 인산화효소(btk)의 억제제의 용도
CN106905311A (zh) 2010-08-27 2017-06-30 钙医学公司 调节细胞内钙的化合物
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CA2767773C (en) 2011-02-11 2015-11-24 Grain Processing Corporation Composition comprising a salt and a crystallization interrupter
WO2012149486A1 (en) 2011-04-28 2012-11-01 Tissuetech, Inc. Methods of modulating bone remodeling
EP2717888B1 (en) 2011-06-10 2020-09-09 Tissuetech, Inc. Methods of processing fetal support tissues
CN103917231B (zh) 2011-09-13 2016-09-28 药品循环有限责任公司 组蛋白脱乙酰酶抑制剂与苯达莫司汀的联合制剂及其用途
US8377946B1 (en) 2011-12-30 2013-02-19 Pharmacyclics, Inc. Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
NZ627750A (en) 2012-01-06 2016-11-25 Abide Therapeutics Inc Carbamate compounds and of making and using same
CN104302689A (zh) 2012-03-14 2015-01-21 麦德医像公司 含有过量活性分子的智能聚合物材料
KR20220093389A (ko) 2012-06-04 2022-07-05 파마싸이클릭스 엘엘씨 브루톤 타이로신 키나아제 저해제의 결정 형태
JP2015528001A (ja) 2012-07-11 2015-09-24 ティッシュテック,インク. Hc−ha/ptx3複合体を含む組成物およびその使用方法
CA2885828C (en) 2012-09-28 2021-04-27 University Of Washington Through Its Center For Commercialization Ureido-thiophenyl derivatives, compositions thereof and methods for preventing, treating and/or protecting against sensory hair cell death
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
US9611263B2 (en) 2013-10-08 2017-04-04 Calcimedica, Inc. Compounds that modulate intracellular calcium
CA2932609A1 (en) 2013-12-05 2015-06-11 Pharmacyclics Llc Inhibitors of bruton's tyrosine kinase
EP3134418A4 (en) 2014-04-23 2018-01-03 The Research Foundation for The State University of New York A rapid and efficient bioorthogonal ligation reaction and boron-containing heterocycles useful in conjuction therewith
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US10080877B2 (en) 2014-07-25 2018-09-25 Warsaw Orthopedic, Inc. Drug delivery device and methods having a drug cartridge
US9839644B2 (en) 2014-09-09 2017-12-12 ARKAY Therapeutics, LLC Formulations and methods for treatment of metabolic syndrome
US9359316B1 (en) 2014-11-25 2016-06-07 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
US10399994B2 (en) 2015-02-06 2019-09-03 University Of Washington Compounds and methods for preventing or treating sensory hair cell death
US10227333B2 (en) 2015-02-11 2019-03-12 Curtana Pharmaceuticals, Inc. Inhibition of OLIG2 activity
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
EP3261631B1 (en) 2015-02-27 2025-09-10 Curtana Pharmaceuticals, Inc. Inhibition of olig2 activity
IL315294A (en) 2015-03-03 2024-10-01 Pharmacyclics Llc Pharmaceutical formulations of bruton's tyrosine kinase inhibitor
MA41828A (fr) 2015-03-27 2018-01-30 Pharmacyclics Llc Co-cristaux d'un inhibiteur de la tyrosine kinase de bruton
MA41827A (fr) 2015-03-27 2018-01-30 Pharmacyclics Llc Formes solvatées d'un inhibiteur de la tyrosine kinase de bruton
KR20180004263A (ko) 2015-05-11 2018-01-10 어바이드 테라퓨틱스, 인크. 염증 또는 신경병성 통증의 치료 방법
HK1250940A1 (zh) 2015-05-20 2019-01-18 Tissuetech, Inc. 用於预防上皮细胞的增殖和上皮-间充质转换的组合物和方法
MX2018002554A (es) 2015-08-31 2018-08-14 Pharmacyclics Llc Combinaciones de inhibidores de btk para tratar mieloma multiple.
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
FI3827838T3 (fi) 2015-12-16 2023-06-19 Walter & Eliza Hall Inst Medical Res Sytokiini-indusoidun sh2-proteiinin estäminen nk-soluissa
US20190282577A1 (en) 2016-01-19 2019-09-19 Janssen Pharmaceutica Nv Formulations/compositions comprising a btk inhibitor
EA201891664A1 (ru) 2016-01-19 2019-02-28 Янссен Фармацевтика Нв Составы/композиции, содержащие ингибитор btk
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US10851123B2 (en) 2016-02-23 2020-12-01 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
CN109310700A (zh) 2016-04-04 2019-02-05 希诺皮亚生物科学公司 使用曲匹地尔治疗锥体外系综合征
CA3025268A1 (en) 2016-05-25 2017-11-30 Concentric Analgesics, Inc. Prodrugs of phenolic trpv1 agonists in combination with local anesthetics and vasoconstrictors for improved local anesthesia
WO2017205769A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
WO2017205762A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
WO2017205766A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
USD802757S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
WO2018005600A1 (en) * 2016-06-28 2018-01-04 Trustees Of Tufts College Compositions and methods for delivery of active agents
CN113214198B (zh) 2016-07-18 2022-12-23 广州瑞安博医药科技有限公司 用于治疗或预防与痛风或高尿酸血症相关的症状的化合物、组合物和方法
MX394015B (es) 2016-08-26 2025-03-24 Curtana Pharmaceuticals Inc Inhibición de la actividad de la olig2.
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
DK3541807T3 (da) 2016-11-16 2021-12-06 H Lundbeck As Krystallinsk form af en magl-inhibitor
MA46867A (fr) 2016-11-16 2019-09-25 Abide Therapeutics Inc Formulations pharmaceutiques
KR20200086257A (ko) 2017-09-01 2020-07-16 유니버시티 오브 워싱톤 감각 모 세포 사멸 예방 또는 치료용 화합물의 결정질 형태
WO2019169112A1 (en) 2018-02-28 2019-09-06 Curtana Pharmaceuticals, Inc. Inhibition of olig2 activity
TW202019887A (zh) 2018-07-27 2020-06-01 美商同心止痛劑股份有限公司 酚系trpv1促效劑之聚乙二醇化前藥
US12145917B2 (en) 2018-12-06 2024-11-19 Arthrosi Therapeutics, Inc. Crystalline forms of a compound for treating or preventing gout or hyperuricemia
CA3125350A1 (en) 2018-12-31 2020-07-09 Biomea Fusion, Llc Irreversible inhibitors of menin-mll interaction
CA3133093A1 (en) 2019-03-15 2020-09-24 Unicycive Therapeutics, Inc. Nicorandil derivatives
CA3175210A1 (en) 2020-04-21 2021-10-28 Cheryl A. Grice Synthesis of a monoacylglycerol lipase inhibitor
CA3202151A1 (en) 2020-12-16 2022-06-23 Biomea Fusion, Inc. Fused pyrimidine compounds as inhibitors of menin-mll interaction
CA3204457A1 (en) 2021-01-06 2022-07-14 Ben SESSA Mdma in the treatment of alcohol use disorder
EP4337316A1 (en) 2021-05-11 2024-03-20 Awakn Ls Europe Holdings Limited Therapeutic aminoindane compounds and compositions
CA3221280A1 (en) 2021-06-03 2022-12-08 Arcadia Medicine, Inc. Enantiomeric entactogen compositions and methods of their use
JP2024531170A (ja) 2021-08-11 2024-08-29 バイオメア フュージョン,インコーポレイテッド 真性糖尿病に対するメニン-mll相互作用の共有結合性阻害剤
TW202313004A (zh) 2021-08-20 2023-04-01 美商拜歐米富士恩股份有限公司 Menin-mll相互作用之不可逆抑制劑的結晶形式
WO2023028092A2 (en) 2021-08-23 2023-03-02 Alexander Shulgin Research Institute Fluorinated empathogens
EP4392028A1 (en) 2021-08-23 2024-07-03 Alexander Shulgin Research Institute, Inc. Deuterated empathogens
WO2023027966A1 (en) 2021-08-24 2023-03-02 Biomea Fusion, Inc. Pyrazine compounds as irreversible inhibitors of flt3
CA3230779A1 (en) 2021-09-03 2023-03-09 Paul Daley Asymmetric allyl tryptamines
WO2023039240A1 (en) 2021-09-13 2023-03-16 Biomea Fusion, Inc. IRREVERSIBLE INHIBITORS OF KRas
WO2023086341A1 (en) 2021-11-09 2023-05-19 Biomea Fusion, Inc. Inhibitors of kras
JP2025502748A (ja) 2021-12-30 2025-01-28 バイオメア フュージョン,インコーポレイテッド Flt3の阻害剤としてのピラジン化合物
US20250100990A1 (en) 2022-01-19 2025-03-27 Awakn Ls Europe Holdings Limited 1,3-benzodioxole esters and their therapeutic use
US20250179089A1 (en) 2022-02-16 2025-06-05 Awakn Ls Europe Holdings Limited Bridged ring compounds and their therapeutic use as cns agents
WO2023235618A1 (en) 2022-06-03 2023-12-07 Biomea Fusion, Inc. Fused pyrimidine compounds as inhibitors of menin
US20240010649A1 (en) 2022-07-06 2024-01-11 Oppilan Pharma Limited Crystalline forms of an s1p receptor modulator
WO2024155719A1 (en) 2023-01-18 2024-07-25 Biomea Fusion, Inc. Crystalline forms of n-[4-[4-(4-morpholinyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(r)-[(l-oxo-2-propen-l-yl)amino]-l-piperidinyl]methyl]-2- pyridinecarboxamide as a covalentinhibitor of menin-mll interaction
US20250002458A1 (en) 2023-05-24 2025-01-02 Unicycive Therapeutics Inc. Salt forms of nicorandil derivative
WO2024249950A1 (en) 2023-06-02 2024-12-05 Biomea Fusion, Inc. Fused pyrimidine compounds as inhibitors of menin
US20250145571A1 (en) 2023-09-26 2025-05-08 Unicycive Therapeutics, Inc. Amino acid prodrugs of nicorandil

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH468192A (de) * 1964-06-19 1969-02-15 Ciba Geigy Verfahren zur Herstellung von Arzneimitteln in Perlenform
IT1050353B (it) * 1966-01-06 1981-03-10 Ceskoslovenska Akademie Ved Supporti per sostanze biologigamente attive
US3660071A (en) * 1966-07-26 1972-05-02 Nat Patent Dev Corp Water soluble entrapping of a pesticide
US3660563A (en) * 1966-07-26 1972-05-02 Nat Patent Dev Corp Water soluble entrapping of a drug
US3577512A (en) * 1968-10-11 1971-05-04 Nat Patent Dev Corp Sustained release tablets
US3576760A (en) * 1969-06-13 1971-04-27 Nat Patent Dev Corp Water soluble entrapping
DE2031871C3 (de) * 1970-06-27 1974-06-27 Roehm Gmbh, 6100 Darmstadt Überzugsmasse für Arzneiformen
GB1394990A (en) * 1971-08-12 1975-05-21 Hydrophilics Int Inc Copolymers and compositions containing copolymers
US4056496A (en) * 1972-10-02 1977-11-01 Corneal Sciences, Inc. Hydrogels and articles made therefrom
US4070348A (en) * 1973-07-25 1978-01-24 Rohm Gmbh Water-swellable, bead copolymer
US4007258A (en) * 1973-09-10 1977-02-08 Union Corporation Sustained release pesticidal composition
US4178361A (en) * 1973-09-10 1979-12-11 Union Corporation Sustained release pharmaceutical composition
CH621561A5 (en) * 1974-01-14 1981-02-13 Ceskoslovenska Akademie Ved Process for producing a bromocyan-activated, hydrophilic, polymeric carrier for biologically active compounds in dried form
US3923939A (en) * 1974-06-07 1975-12-02 Alza Corp Process for improving release kinetics of a monolithic drug delivery device
US4177056A (en) * 1974-06-27 1979-12-04 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
US4248855A (en) * 1976-08-27 1981-02-03 Hydrophilics International, Inc. Pharmaceutical base salts
US4164560A (en) * 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4304591A (en) * 1978-01-25 1981-12-08 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
DE2908794C2 (de) * 1978-03-09 1984-09-13 Japan Atomic Energy Research Institute, Tokio/Tokyo Verfahren zur Herstellung eines eine physiologisch aktive Substanz enthaltenden Polymerpräparates
US4267295A (en) * 1979-02-09 1981-05-12 Syntex (U.S.A.) Inc. Polymeric compositions and hydrogels formed therefrom
US4357312A (en) * 1981-07-16 1982-11-02 The Children's Hospital Medical Center Method of making prolonged release body
IL70071A (en) * 1982-11-01 1987-12-31 Merrell Dow Pharma Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient
US4564364A (en) * 1983-05-26 1986-01-14 Alza Corporation Active agent dispenser
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device

Also Published As

Publication number Publication date
IL75129A (en) 1989-08-15
FI851801A7 (fi) 1985-11-11
US4624848A (en) 1986-11-25
EP0164311A2 (en) 1985-12-11
ATE61731T1 (de) 1991-04-15
PT80416A (en) 1985-06-01
FI851801A0 (fi) 1985-05-08
NZ212030A (en) 1988-01-08
JPS619A (ja) 1986-01-06
PT80416B (en) 1987-04-16
IL75129A0 (en) 1985-09-29
DK205185D0 (da) 1985-05-09
ES542948A0 (es) 1986-01-01
PH24100A (en) 1990-03-05
FI851801L (fi) 1985-11-11
EP0164311A3 (en) 1987-06-03
AU4221685A (en) 1985-11-14
CA1246447A (en) 1988-12-13
DE3582193D1 (de) 1991-04-25
EP0164311B1 (en) 1991-03-20
ES8603273A1 (es) 1986-01-01
AU583507B2 (en) 1989-05-04
ZA853511B (en) 1985-12-24
GR851114B (forum.php) 1985-11-25

Similar Documents

Publication Publication Date Title
DK205185A (da) Hydrogelmaterialer med indhold af aktivt stof samt deres fremstilling og anvendelse
DK0386440T3 (da) Lægemidler med kontrolleret afgivelse af virksomt stof
FI852894L (fi) Doseringsanordning foer frigoering av ett aktivt aemne i en loesningsvaetska med konstant hastighet och foerfarande foer dess framstaellning.
DK400181A (da) Sammensatte materialer indeholdende immobiliserede biologisk aktive arter fremgangsmaade til deres fremstilling samt deres anvendelse
BR8103649A (pt) Dispositivo e processo para a liberacao controlade de um material ativo em um meio liquido processo para fazer um corpo soluvel ser humano ou animal
DK161011C (da) Praeparat til kontinuerlig frigivelse af naeringsstoffer og/eller terapeutiske stoffer til droevtyggere samt fremgangsmaade til fremstilling heraf
DK365282A (da) Fremgangsmaade til fremstilling af et kombinationspraeparat
EP0013606A3 (en) Polymeric diffusion matrix, method of its preparation and drug delivery device comprising said matrix
NL175475C (nl) Transport- en opslagreservoir voor radioactieve stoffen, in het bijzonder voor bestraalde brandelementen.
DK517782A (da) Fremgangsmaade til udbygning af lipidindholdet af en dyrket nitroorganisme samt carbonfrit kopipapir indeholdende et saaledes udbygget lipid
DK152831C (da) Fremgangsmaade ved fremstilling af biologisk aktive praeparater med reguleret afgivelse af aktivt stof samt polymerbaseret vaeskeformigt overtraekspraeparat til anvendelse ved fremgangsmaaden
Lee et al. Fluoride ion diffusion from a glass–ionomer cement
FI940249L (fi) Menetelmä ja laite vaikuttavan nesteen injisioimiseksi puumateriaaliin ja huokoiseen epäorgaaniseen materiaaliin, ja menetelmä ydinsädesolun peruskudoksen seinämien ja imukuoppaparien tuhoamiseksi
ES8601756A1 (es) Metodo de fabricar una estructura compuesta coherente.
DK325677A (da) Preparat med regulert aktivstoffrigorelse samt fremgangsmade til fremstilling deraf
ES473731A1 (es) Procedimiento para la fabricacion de un material de registrosensible a la presion.
Escolar et al. Effect of low temperatures on glucose-induced insulin secretion and ionic fluxes in rat pancreatic islets
ES2073454T3 (es) Soporte para moleculas biologicamente activas o a su vez biologicamente activo, su procedimiento de preparacion y su aplicacion en biologia.
ES2155131T3 (es) Proceso para la fabricacion de dispositivos para la liberacion controlada de principios activos.
JPS52156775A (en) Production of microcapsule
JPS52130980A (en) Immobilization of glucoseisomerase
MX5150E (es) Procedimiento para preparar un copolimero de bloque hidrofilico que contiene un agente biologicamente activo

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment