DK2048236T3 - Genekspressionsteknik - Google Patents

Genekspressionsteknik

Info

Publication number
DK2048236T3
DK2048236T3 DK08169442.4T DK08169442T DK2048236T3 DK 2048236 T3 DK2048236 T3 DK 2048236T3 DK 08169442 T DK08169442 T DK 08169442T DK 2048236 T3 DK2048236 T3 DK 2048236T3
Authority
DK
Denmark
Prior art keywords
protein
gene encoding
host cell
heterologous protein
gene expression
Prior art date
Application number
DK08169442.4T
Other languages
English (en)
Inventor
Darrell Sleep
Gillian Shuttleworth
Christopher John Arthur Finnis
Original Assignee
Novozymes Biopharma Dk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biopharma Dk As filed Critical Novozymes Biopharma Dk As
Application granted granted Critical
Publication of DK2048236T3 publication Critical patent/DK2048236T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK08169442.4T 2003-12-23 2004-12-23 Genekspressionsteknik DK2048236T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329681.1A GB0329681D0 (en) 2003-12-23 2003-12-23 Gene expression technique
EP04806256A EP1709181B1 (en) 2003-12-23 2004-12-23 Gene expression technique

Publications (1)

Publication Number Publication Date
DK2048236T3 true DK2048236T3 (da) 2013-05-21

Family

ID=30776264

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08169442.4T DK2048236T3 (da) 2003-12-23 2004-12-23 Genekspressionsteknik

Country Status (16)

Country Link
US (3) US20070275889A1 (da)
EP (2) EP2048236B1 (da)
JP (1) JP5052899B2 (da)
KR (1) KR101262682B1 (da)
CN (2) CN1922325B (da)
AT (1) ATE421994T1 (da)
AU (2) AU2004303601C1 (da)
CA (1) CA2551503A1 (da)
DE (1) DE602004019304D1 (da)
DK (1) DK2048236T3 (da)
ES (1) ES2321948T3 (da)
GB (2) GB0329681D0 (da)
HK (1) HK1099938A1 (da)
SG (2) SG149003A1 (da)
WO (1) WO2005061718A1 (da)
ZA (1) ZA200605588B (da)

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SG2014012918A (en) 2009-02-11 2014-04-28 Novozymes Biopharma Dk As Albumin variants and conjugates
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US20140315817A1 (en) 2011-11-18 2014-10-23 Eleven Biotherapeutics, Inc. Variant serum albumin with improved half-life and other properties
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CA2890766A1 (en) 2012-11-08 2014-05-15 Novozymes Biopharma Dk A/S Albumin variants
CN102994541B (zh) * 2012-12-19 2015-04-15 江南大学 一种共表达upr关键基因和下游靶基因增强葡萄糖氧化酶分泌的方法
WO2014132497A1 (ja) 2013-02-28 2014-09-04 株式会社日立ハイテクノロジーズ データ解析装置、及びその方法
CN103436516B (zh) * 2013-08-23 2015-04-22 华南理工大学 利用大肠杆菌原核表达系统生产的小麦蛋白质二硫键异构酶及方法和应用
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CA2948369C (en) 2014-04-17 2023-09-26 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell engineered to overexpress helper proteins
CA2989966C (en) 2015-08-20 2024-04-30 Albumedix A/S Albumin variants and conjugates
WO2017112847A1 (en) 2015-12-22 2017-06-29 Albumedix A/S Improved protein expression strains
CA3023046A1 (en) * 2016-05-04 2017-11-09 Shenzhen Protgen Ltd. Construction of engineering bacteria for high expression of recombinant human serum albumin
CN106834322B (zh) * 2017-03-14 2020-09-04 中国科学院南海海洋研究所 抗毒素so_1445或其编码基因在提高质粒在宿主细胞中的稳定性中的应用
CA3064037A1 (en) 2017-06-20 2018-12-27 Albumedix Ltd Improved protein expression strains
WO2019006348A1 (en) * 2017-06-30 2019-01-03 Western University Of Health Sciences IX-TRANSFERRIN FACTOR FUSION PROTEINS
CN112004931A (zh) 2018-03-26 2020-11-27 诺维信公司 真菌伴侣蛋白
CN112391402B (zh) * 2020-11-17 2023-03-28 华中科技大学 一种提高解脂耶氏酵母中目的蛋白表达水平的方法
CN116981778A (zh) * 2021-03-10 2023-10-31 住友制药株式会社 半胱氨酸结蛋白的制造方法
CN114410496B (zh) * 2022-02-16 2023-10-03 江南大学 一种提高毕赤酵母外源蛋白产量的方法

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Also Published As

Publication number Publication date
GB0329681D0 (en) 2004-01-28
KR101262682B1 (ko) 2013-05-15
AU2008202538A1 (en) 2008-06-26
AU2004303601A1 (en) 2005-07-07
EP2048236B1 (en) 2013-03-20
ZA200605588B (en) 2009-02-25
AU2004303601C1 (en) 2009-01-08
JP2007515962A (ja) 2007-06-21
HK1099938A1 (en) 2007-08-31
US20180105818A1 (en) 2018-04-19
ES2321948T3 (es) 2009-06-15
CN1922325B (zh) 2010-06-09
EP1709181B1 (en) 2009-01-28
CN1922325A (zh) 2007-02-28
CN101818121A (zh) 2010-09-01
SG149003A1 (en) 2009-01-29
SG182155A1 (en) 2012-07-30
DE602004019304D1 (de) 2009-03-19
EP2048236A1 (en) 2009-04-15
WO2005061718A1 (en) 2005-07-07
AU2004303601B2 (en) 2008-03-06
GB0614614D0 (en) 2006-08-30
JP5052899B2 (ja) 2012-10-17
CA2551503A1 (en) 2005-07-07
US20120231503A1 (en) 2012-09-13
GB2424889A (en) 2006-10-11
US20070275889A1 (en) 2007-11-29
KR20070005568A (ko) 2007-01-10
EP1709181A1 (en) 2006-10-11
ATE421994T1 (de) 2009-02-15

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