DK2035457T3 - Vaccinebærer - Google Patents

Vaccinebærer Download PDF

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Publication number
DK2035457T3
DK2035457T3 DK07718492.7T DK07718492T DK2035457T3 DK 2035457 T3 DK2035457 T3 DK 2035457T3 DK 07718492 T DK07718492 T DK 07718492T DK 2035457 T3 DK2035457 T3 DK 2035457T3
Authority
DK
Denmark
Prior art keywords
glu
ala
lys
leu
asp
Prior art date
Application number
DK07718492.7T
Other languages
English (en)
Inventor
Rudolf Valenta
Margarete Focke-Tejkl
Birgit Linhart
Susanne Vrtala
Peter Valent
Renate Reininger
Susanne Spitzauer
Ines Swoboda
Hage Marianne Van
Kerstin Westritschnig
Theresia Popow-Kraupp
Hans Grönlund
Johanna Tinhofer
Original Assignee
Biomay Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomay Ag filed Critical Biomay Ag
Application granted granted Critical
Publication of DK2035457T3 publication Critical patent/DK2035457T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • A61K39/36Allergens from pollen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32711Rhinovirus
    • C12N2770/32734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK07718492.7T 2006-06-09 2007-06-11 Vaccinebærer DK2035457T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0099406A AT503690A1 (de) 2006-06-09 2006-06-09 Hypoallergene moleküle
PCT/AT2007/000281 WO2007140505A2 (en) 2006-06-09 2007-06-11 Vaccine carrier

Publications (1)

Publication Number Publication Date
DK2035457T3 true DK2035457T3 (da) 2015-06-15

Family

ID=38650124

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15161237.1T DK2924047T3 (da) 2006-06-09 2007-06-11 Vaccinebærer
DK07718492.7T DK2035457T3 (da) 2006-06-09 2007-06-11 Vaccinebærer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK15161237.1T DK2924047T3 (da) 2006-06-09 2007-06-11 Vaccinebærer

Country Status (14)

Country Link
US (2) US9296828B2 (da)
EP (2) EP2035457B1 (da)
JP (3) JP5399895B2 (da)
CN (3) CN101466738A (da)
AT (1) AT503690A1 (da)
AU (1) AU2007257308B2 (da)
BR (1) BR122019004393B1 (da)
CA (1) CA2657971C (da)
DK (2) DK2924047T3 (da)
ES (2) ES2698525T3 (da)
PL (1) PL2035457T3 (da)
PT (1) PT2035457E (da)
RU (1) RU2486206C2 (da)
WO (1) WO2007140505A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2190473T3 (da) 2007-08-15 2013-03-25 Circassia Ltd Peptid med reduceret dimerdannelse
PT2153841E (pt) * 2008-08-15 2012-03-21 Circassia Ltd Vacina compreendendo péptidos amb a 1 para utilização no tratamento de alergia a ambrósia
EP2384336B1 (en) * 2008-12-30 2014-03-05 Chua, Kaw Yan A variant of mite allergen and uses thereof
CO6260019A1 (es) 2009-01-30 2011-03-22 Fundacion Universidad Del Norte Metodo y composicion inmunoquimica para la deteccion de alergenos de acaros usando anticuerpos policlonales igy
US8753644B2 (en) * 2009-02-05 2014-06-17 Circassia Limited Grass peptides for vaccine
AU2013202362B2 (en) * 2009-02-05 2015-09-17 Circassia Limited Grass Peptides for Vaccine
EP2316481A1 (en) * 2009-10-30 2011-05-04 Biomay Ag Pharmaceutical composition for the treatment and prevention of a rhinovirus infection
US9308251B2 (en) * 2011-06-09 2016-04-12 Biomay Ag Peptide carrier fusion proteins as allergy vaccines
AU2012277491B2 (en) * 2011-06-27 2017-03-23 Anergis S.A. Contiguous overlapping peptides for treatment of ragweed pollen allergy
EP2543725A1 (en) * 2011-07-08 2013-01-09 Biomay Ag Polysaccharide lyases
JO3820B1 (ar) 2012-05-03 2021-01-31 Regeneron Pharma أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها
GB201209868D0 (en) * 2012-06-01 2012-07-18 Circassia Ltd Alternaria peptides
EP2727934B1 (en) 2012-09-20 2016-06-15 Universidad de Cartagena Fusion proteins with representation of different allergens: vaccine proposal for mite allergies
JP2014231500A (ja) * 2013-05-29 2014-12-11 元晴 植原 シラカンバ花粉症の免疫療法に用いるペプチド混合物
EP3564671B1 (en) 2013-08-23 2021-09-29 Regeneron Pharmaceuticals, Inc. Diagnostic tests and methods for assessing safety, efficacy or outcome of allergen-specific immunotherapy (sit)
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
US11352417B2 (en) 2016-12-22 2022-06-07 Regeneron Pharmaceuticals, Inc. Method of treating an allergy with allergen-specific monoclonal antibodies
US11408895B1 (en) 2018-04-09 2022-08-09 Hob Biotech Group Corp., Ltd. Allergen characterization, potent allergen product formulation, comprehensive allergen reagent, and allergy assay
EP3569612A1 (en) * 2018-05-18 2019-11-20 Biomay Ag Treatment and prevention of house dust mite allergies
RU2761431C9 (ru) 2020-10-26 2022-04-18 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8821077D0 (en) 1988-09-08 1988-10-05 Wellcome Found Peptides
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6019972A (en) * 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
NZ244782A (en) * 1991-10-16 1996-12-20 Immulogic Pharma Corp Isolated peptides having t-cell stimulating activity, pharmaceutical composition
IL105153A (en) * 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AT401937B (de) * 1993-04-01 1996-12-27 Biomay Prod & Handel Rekombinantes lieschgras pollen allergen phl p ii
DE69333979T2 (de) * 1993-04-14 2006-12-21 Heska Corp.(n.d.Ges, d.Staates Delaware), Loveland T-zell epitope der hauptallergene von dermatophagoides (hausstaubmilbe)
DK0755407T3 (da) * 1994-04-14 2007-08-06 Merck Patent Gmbh Farmaceutisk peptidformuleringer til behandling af stövmideallergi
SE9402089D0 (sv) * 1994-06-14 1994-06-14 Rudolf Valenta Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments
US6572859B1 (en) * 1999-10-29 2003-06-03 Pharmacia Diagnostics Ab Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use
US20030166518A1 (en) * 2000-01-13 2003-09-04 Beardslee Thomas A. Method for allergen characterization
DE60137230D1 (de) 2000-07-06 2009-02-12 Univ Georgetown Stabile (fixierte) formen von viralen l1 capsidproteinen, deren fusionsproteinen, und deren verwendungen
ES2209563B1 (es) 2000-07-28 2005-10-01 Universidad Complutense De Madrid Produccion en la levadurapipchia pastoris y sistema de purificacion del alergeno recombinante de olea europaea ole e 1 para uso en diagnosis y tratamiento de alergias.
NZ525820A (en) 2000-11-16 2005-01-28 Alk Abello As Mutant allergens
EP1221317A1 (en) * 2000-12-28 2002-07-10 SHAN-Beteiligungsgesellschaft m.b.H. Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins
US7264810B2 (en) * 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
ATE443716T1 (de) 2002-02-27 2009-10-15 Merck Patent Gmbh Verfahren zur herstellung von hypoallergenem birkenpollenhauptallergen rbet v 1
EP1534344A4 (en) 2002-06-26 2008-05-28 Advanced Bionutrition Corp VIRUSES AND VIRUSIC PARTICLES FOR MULTIPLE ANTIGEN AND TARGET DISPLAY
JP4953570B2 (ja) 2002-07-05 2012-06-13 フォリア バイオテック インコーポレイテッド アジュバントウィルス粒子
DE60301944T2 (de) 2003-01-21 2006-06-01 Biomay Produktions- Und Handels-Aktiengesellschaft Verfahren zur Vorbereitung von hypoallergenen Mosaikproteinen#
GB0308988D0 (en) 2003-04-17 2003-05-28 Univ Singapore Molecule
ES2434720T3 (es) * 2003-06-04 2013-12-17 Merck Patent Gmbh Derivados de LOL P 5 con alergenicidad reducida y reactividad frente a células T mantenida
US20050053615A1 (en) * 2003-07-16 2005-03-10 Best Elaine A. Variants of mite group 1 allergens for the treatment of house dust mite allergy
DE10351471A1 (de) * 2003-11-04 2005-06-09 Ursula Prof. Dr. Wiedermann-Schmidt Polyvalente Allergievakzine
MXPA06006221A (es) * 2003-12-01 2008-02-13 Dow Global Technologies Inc Produccion de particula tipo virus icosaedrico recombinante en organismos del genero pseudomonas.
CN1926238A (zh) * 2004-02-27 2007-03-07 陶氏化学公司 植物细胞中的高效肽生产
ITRM20040103A1 (it) * 2004-02-27 2004-05-27 Consiglio Nazionale Ricerche Proteine di fusione comprendenti allergeni della famiglia delle ns-ltps, loro usi e composizioni farmaceutiche che le comprendono.
US20060088549A1 (en) * 2004-07-08 2006-04-27 Arnold Gail F Chimeric virus vaccine
DE102004035337A1 (de) 2004-07-21 2006-03-16 Merck Patent Gmbh Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität
MX2007003171A (es) * 2004-09-21 2007-05-23 Cytos Biotechnology Ag Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico.
AT501101B1 (de) 2004-12-02 2008-01-15 Biomay Ag Protein-allergen-derivat
US7767212B2 (en) * 2005-03-18 2010-08-03 Cytos Biotechnology Ag CAT allergen conjugates and uses thereof
AU2006291835B2 (en) * 2005-09-15 2012-04-05 Alk-Abello A/S A method for quantification of allergens

Also Published As

Publication number Publication date
US20090324501A1 (en) 2009-12-31
CN103319602A (zh) 2013-09-25
BR122019004393B1 (pt) 2023-10-17
AU2007257308B2 (en) 2013-06-06
CA2657971C (en) 2018-01-23
PT2035457E (pt) 2015-07-28
JP5399895B2 (ja) 2014-01-29
US20160257722A1 (en) 2016-09-08
WO2007140505A3 (en) 2008-03-20
DK2924047T3 (da) 2018-12-03
JP2014087341A (ja) 2014-05-15
ES2698525T3 (es) 2019-02-05
CN101466738A (zh) 2009-06-24
WO2007140505A2 (en) 2007-12-13
AU2007257308A1 (en) 2007-12-13
US9296828B2 (en) 2016-03-29
CA2657971A1 (en) 2007-12-13
CN103319602B (zh) 2016-09-07
RU2486206C2 (ru) 2013-06-27
EP2924047A1 (en) 2015-09-30
PL2035457T3 (pl) 2015-10-30
EP2035457A2 (en) 2009-03-18
EP2035457B1 (en) 2015-04-01
RU2008152045A (ru) 2010-07-20
JP2014064573A (ja) 2014-04-17
JP2009539354A (ja) 2009-11-19
BRPI0712421A2 (pt) 2012-06-19
EP2924047B1 (en) 2018-08-22
ES2541311T3 (es) 2015-07-17
CN103319601A (zh) 2013-09-25
AT503690A1 (de) 2007-12-15

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