DK2006389T3 - Fremgangsmåde til fremstilling af koncentreret flerumættet fedtsyreolie - Google Patents

Fremgangsmåde til fremstilling af koncentreret flerumættet fedtsyreolie Download PDF

Info

Publication number
DK2006389T3
DK2006389T3 DK07741570.1T DK07741570T DK2006389T3 DK 2006389 T3 DK2006389 T3 DK 2006389T3 DK 07741570 T DK07741570 T DK 07741570T DK 2006389 T3 DK2006389 T3 DK 2006389T3
Authority
DK
Denmark
Prior art keywords
oil
reaction
polyunsaturated fatty
lipase
fatty acid
Prior art date
Application number
DK07741570.1T
Other languages
English (en)
Inventor
Kiyomi Furihata
Hiroyuki Kawahara
Nobushige Doisaki
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Application granted granted Critical
Publication of DK2006389T3 publication Critical patent/DK2006389T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6454—Glycerides by esterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)

Claims (6)

1. Fremgangsmåde til fremstilling af koncentreret, flerumættet fedtsyreolie, hvilken fremgangsmåde omfatter. at underkaste olie og fedt, som indeholder flerumættede fedtsyrer som fedtsyrebe-standdel, alkoholysereaktion under anvendelse af lipase i nærvær af en alkohol og vand og mindst én forbindelse som reaktionstilsætningsstof udvalgt blandt magnesiumoxid, magnesiumhydroxid, calciumoxid og calciumhydroxid, hvor mængden af tilsat vand er 1 % til 30 % (vol/vol) i forhold til alkoholen, hvor lipasen er udvalgt blandt lipaser opnået fra mikroorganismerne Alcaligenes sp., Thermomyces lanuginosus, Burkholderia cepacia og Pseudomonas fluorescens, og hvor de flerumættede fedtsyrer har 20 til 22 carbonatomer og 4 til 6 dobbeltbindinger; og at fraseparere en glyceridfraktion, hvori flerumættede fedtsyrer er opkoncentrerede.
2. Fremgangsmåde ifølge krav 1, hvor reaktionstilsætningsstoffet er magnesiumoxid.
3. Fremgangsmåde ifølge krav 1 eller 2, hvor alkoholysereaktionen er ethanolyse.
4. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 3, hvor den flerumættede fedtsyre er eicosapentaensyre og/eller docosahexaensyre.
5. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 4, hvor den olie- og fedtholdige flerumættede fedtsyre er fiskeolie.
6. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, hvor mængden af reaktionstilsætningsstoffet er 0,01 % til 30 % efter vægt i forhold til den olie- og fedtholdige flerumættede fedtsyre.
DK07741570.1T 2006-04-13 2007-04-13 Fremgangsmåde til fremstilling af koncentreret flerumættet fedtsyreolie DK2006389T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006111039 2006-04-13
PCT/JP2007/058134 WO2007119811A1 (ja) 2006-04-13 2007-04-13 高度不飽和脂肪酸濃縮油の製造方法

Publications (1)

Publication Number Publication Date
DK2006389T3 true DK2006389T3 (da) 2017-08-28

Family

ID=38609571

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07741570.1T DK2006389T3 (da) 2006-04-13 2007-04-13 Fremgangsmåde til fremstilling af koncentreret flerumættet fedtsyreolie

Country Status (7)

Country Link
US (1) US9150817B2 (da)
EP (1) EP2006389B1 (da)
JP (1) JP5111363B2 (da)
CA (1) CA2649337C (da)
DK (1) DK2006389T3 (da)
NO (1) NO20084220L (da)
WO (1) WO2007119811A1 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9549739B2 (en) 2005-05-20 2017-01-24 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US7645286B2 (en) 2005-05-20 2010-01-12 Neotract, Inc. Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures
US8668705B2 (en) 2005-05-20 2014-03-11 Neotract, Inc. Latching anchor device
US7758594B2 (en) 2005-05-20 2010-07-20 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US8628542B2 (en) 2005-05-20 2014-01-14 Neotract, Inc. Median lobe destruction apparatus and method
US8603106B2 (en) 2005-05-20 2013-12-10 Neotract, Inc. Integrated handle assembly for anchor delivery system
US10195014B2 (en) 2005-05-20 2019-02-05 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US10925587B2 (en) 2005-05-20 2021-02-23 Neotract, Inc. Anchor delivery system
EP1978102B1 (de) 2007-04-02 2010-07-07 Cognis IP Management GmbH Ein Gemisch enthaltend Fettsäureglyceride
EP1978101A1 (de) 2007-04-02 2008-10-08 Cognis IP Management GmbH Verfahren zur Anreicherung mehrfach ungesättigter Fettsäuren
KR101502191B1 (ko) * 2007-07-30 2015-03-12 닛폰 스이산 가부시키가이샤 Ｅｐａ 농축유 및 ｄｈａ 농축유의 제조 방법
JP5545695B2 (ja) * 2007-11-16 2014-07-09 水澤化学工業株式会社 バイオ燃料の製造方法
JP5237627B2 (ja) * 2007-12-27 2013-07-17 株式会社マルハニチロ水産 高度不飽和脂肪酸の濃縮方法
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
JP5405193B2 (ja) * 2009-05-15 2014-02-05 水澤化学工業株式会社 バイオ燃料の製造方法
PE20130491A1 (es) 2009-12-30 2013-05-02 Basf Pharma Callanish Ltd Proceso simulado de separacion cromatografica de lecho movil para la purificacion de acidos grasos poliinsaturados
US20130123525A1 (en) * 2010-05-28 2013-05-16 Nippon Suisan Kaisha, Ltd. Method for producing oil containing polyunsaturated fatty acid using lipase
CN103338762B (zh) 2010-11-09 2015-03-25 持田制药株式会社 血糖值上升抑制剂
EP2682453B2 (en) 2011-03-03 2023-03-22 Nissui Corporation Method of producing oil/fat comprising highly-unsaturated fatty acids by means of lipase
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
JP5836025B2 (ja) * 2011-09-07 2015-12-24 日本水産株式会社 高度不飽和脂肪酸濃縮油の製造方法
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
CA2856715A1 (en) * 2011-11-29 2013-06-06 Dignity Sciences Limited Compositions comprising 20-carbon fatty acids and methods of making and using same
US10292801B2 (en) 2012-03-29 2019-05-21 Neotract, Inc. System for delivering anchors for treating incontinence
US10130353B2 (en) 2012-06-29 2018-11-20 Neotract, Inc. Flexible system for delivering an anchor
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
JP5852972B2 (ja) * 2013-02-13 2016-02-03 マルハニチロ株式会社 高度不飽和脂肪酸の濃縮方法
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP3118186B1 (fr) 2013-12-11 2022-02-09 Novasep Process Installation chromatographique de production d acides gras polyinsatures
BR112016015718B1 (pt) 2014-01-07 2021-12-07 Novasep Process Solutions Processo de purificação de aminoácidos aromáticos
US20180051304A1 (en) * 2015-03-25 2018-02-22 Kewpie Corporation Method for Producing DHA-Containing Glyceride-Containing Composition
JP2018085931A (ja) * 2015-04-01 2018-06-07 キユーピー株式会社 低級アルコール脂肪酸エステル化物含有組成物の製造方法および低級アルコール脂肪酸エステル化物含有組成物
SG11202005766XA (en) 2017-12-23 2020-07-29 Neotract Inc Expandable tissue engagement apparatus and method
EP3848466A4 (en) * 2018-09-04 2022-06-15 Nippon Suisan Kaisha, Ltd. METHOD FOR PRODUCTION OF GLYCERIDE CONTAINING POLYUNSATURATED FATTY ACID BY MEANS OF LIPASE HYDROLYSIS REACTION
CN109355323A (zh) * 2018-11-23 2019-02-19 福州大学 一种低温复合脂肪酶在酯交换中提高甘油酯型ω-3脂肪酸含量的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274159A (en) * 1963-01-07 1966-09-20 Union Carbide Corp Polyester imides of trimellitic anhydride
JPS58165796A (ja) * 1982-03-26 1983-09-30 Asahi Denka Kogyo Kk 長鎖高度不飽和脂肪酸グリセリドの濃縮法
JPS5914793A (ja) * 1982-07-16 1984-01-25 Nippon Oil & Fats Co Ltd 高度不飽和脂肪酸低級アルコ−ルエステルの濃縮分離方法
JPH0716425B2 (ja) * 1987-05-20 1995-03-01 花王株式会社 油脂類のエステル交換反応方法
US5935828A (en) * 1989-05-01 1999-08-10 Opta Food Ingredients, Inc. Enzymatic production of monoglycerides containing omega-3 unsaturated fatty acids
JPH03108489A (ja) * 1989-09-22 1991-05-08 Meito Sangyo Kk 長鎖高度不飽和脂肪酸モノグリセリドの製造法
GB9404483D0 (en) * 1994-03-08 1994-04-20 Norsk Hydro As Refining marine oil compositions
US5968792A (en) 1996-12-19 1999-10-19 Henkel Corporation Calcium activation of lipase enzyme in process of pressure splitting glycerides
JP3813585B2 (ja) * 2003-01-23 2006-08-23 花王株式会社 ジグリセリドの製造方法
DE102005002711A1 (de) 2005-01-19 2006-07-27 Cognis Deutschland Gmbh & Co. Kg Herstellung und Verwendung von Monoglyceriden

Also Published As

Publication number Publication date
JPWO2007119811A1 (ja) 2009-08-27
US20090176284A1 (en) 2009-07-09
EP2006389A2 (en) 2008-12-24
NO20084220L (no) 2009-01-13
CA2649337A1 (en) 2007-10-25
WO2007119811A1 (ja) 2007-10-25
EP2006389B1 (en) 2017-05-31
CA2649337C (en) 2014-11-18
JP5111363B2 (ja) 2013-01-09
US9150817B2 (en) 2015-10-06
EP2006389A9 (en) 2009-04-08
EP2006389A4 (en) 2013-01-09

Similar Documents

Publication Publication Date Title
DK2006389T3 (da) Fremgangsmåde til fremstilling af koncentreret flerumættet fedtsyreolie
DK2172558T3 (da) Fremgangsmåde til fremstilling af en EPA-beriget olie og DHA-beriget olie
KR100538480B1 (ko) 리파아제를 이용한 글리세리드의 제조방법
CA2803477C (en) Process for separating polyunsaturated fatty acids from long chain unsaturated or less saturated fatty acids
KR20130111233A (ko) 리파아제에 의한 고도 불포화 지방산 함유 유지의 제조 방법
JP7365346B2 (ja) リパーゼ加水分解反応を用いる高度不飽和脂肪酸含有グリセリドの製造方法
JP6175198B2 (ja) Ｄｈａ含有グリセリド含有組成物の製造方法
JP3840459B2 (ja) グリセリドおよびその製造方法
WO2008093378A1 (en) Process of selective enzymatic enrichment of a mixture containing omega-3
JP2020174570A (ja) 高度不飽和脂肪酸及び中鎖脂肪酸含有トリグリセリドの製造方法
JP5836025B2 (ja) 高度不飽和脂肪酸濃縮油の製造方法
JPH08214891A (ja) 高度不飽和脂肪酸含有トリグリセリドを含む油脂の製造方法
JPH10265795A (ja) 水和性を高めた高度不飽和脂肪酸含有油脂組成物
US20080242879A1 (en) Process for enriching polyunsaturated fatty acids
JP2008278781A (ja) ２位よりも１，３位のｄｈａ含有率が高いトリアシルグリセロールの製造方法
US20210324432A1 (en) Method of producing docosahexaenoic acid containing glyceride using a lipase hydrolysis reaction