DK1981915T3 - Sammensætninger af aktive bestanddele - Google Patents

Sammensætninger af aktive bestanddele Download PDF

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Publication number
DK1981915T3
DK1981915T3 DK07703313.2T DK07703313T DK1981915T3 DK 1981915 T3 DK1981915 T3 DK 1981915T3 DK 07703313 T DK07703313 T DK 07703313T DK 1981915 T3 DK1981915 T3 DK 1981915T3
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DK
Denmark
Prior art keywords
range
starch
soluble
modified polysaccharide
osa
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DK07703313.2T
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English (en)
Inventor
David Schaffner
Christian Schäfer
Bernd Schlegel
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Dsm Ip Assets Bv
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/58Colouring agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00Preparation of derivatives of starch
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/212Starch; Modified starch; Starch derivatives, e.g. esters or ethers
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • A23L33/155Vitamins A or D
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40Colouring or decolouring of foods
    • A23L5/42Addition of dyes or pigments, e.g. in combination with optical brighteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40Colouring or decolouring of foods
    • A23L5/42Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/0008Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/02Starch; Degradation products thereof, e.g. dextrin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/04Starch derivatives, e.g. crosslinked derivatives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/04Starch derivatives, e.g. crosslinked derivatives
    • C08L3/06Esters
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Claims (14)

1. Fremgangsmåde til fremstilling af et forbedret modificeret polysaccharid, hvilken fremgangsmåde omfatter følgende trin: a) fremstilling af en vandig opløsning eller suspension af et modificeret polysaccharid med et tørvægtsindhold i intervallet fra 0,5 til 80 vægt-%, baseret på den samlede vægt af den vandige opløsning eller suspension, hvorved vandets temperatur fortrinsvis ligger i intervallet fra 1 til < 100 °C; b) fraseparation af dele af det modificerede polysaccharid i vand ved en temperatur i intervallet fra 1 til < 100 °C, c) eventuelt omdannelse af det således opnåede forbedrede modificerede polysaccharid til en fast form; hvor trin b) udføres ved sedimentering/centrifugering og mikrofiltrering, og tørvægtsindholdet i den vandige opløsning eller suspension af det modificerede polysaccharid i trin a) ligger i intervallet fra 0,5 til 80 vægt-%, og hvor det modificerede polysaccharid er en OSA-stivelse (stiveIsenatriumoctenylsuccinat) .
2. Fremgangsmåde ifølge krav 1, hvor vandet i trin a) har en temperatur i intervallet fra 30 til 75 °C.
3. Fremgangsmåde ifølge krav 1 eller 2, hvor sedimenteringen/centrifugeringen i trin b) udføres først og efterfølges af filtreringen.
4. Fremgangsmåde ifølge et eller flere af kravene 1-3, hvor temperaturen, ved hvilken trin b) udføres, ligger i intervallet fra 1 til < 100 °C, fortrinsvis i intervallet fra 30 til 70 °C.
5. Sammensætning, som omfatter i) mindst et forbedret modificeret polysaccharid, der er opnået ved fremgangsmåden ifølge et hvilket som helst af kravene 1-4; ii) mindst en fedtopløselig aktiv bestanddel og/eller et farvestof og iii) eventuelt mindst en adjuvans og/eller en excipiens.
6. Sammensætning ifølge krav 5, hvor det forbedrede modificerede polysaccharid er et modificeret polysaccharid, hvis 10 % vandige opløsning har en turbiditet i intervallet fra 1 til 200 NTU, fortrinsvis i intervallet fra 1 til 150 NTU, mere fortrinsvis i intervallet fra 1 til 110 NTU, mest fortrinsvis i intervallet fra 1 til 100 NTU.
7. Sammensætning ifølge et hvilket som helst af kravene 5-6, hvor den fedtopløselige aktive bestanddel og eller farvestoffet ii) er et caroten eller en strukturelt beslægtet polyenforbindelse, et fedtopløseligt vitamin, et triglycerid, der er rigt på polyumættede fedtsyrer, et olieopløseligt UV-A-filter, et UV-B-filter eller en blanding deraf.
8. Sammensætning ifølge krav 7, hvor carotenet eller den strukturelt beslægtede polyenforbindelse er et carotenoid, navnlig β-caroten.
9. Sammensætning ifølge krav 7, hvor det fedtopløselige vitamin er A- eller E-vitamin.
10. Sammensætning ifølge et hvilket som helst af kravene 5-9, hvor der desuden er en co-emulgator til stede, som er valgt fra gruppen bestående af mono- og diglycerider af fedtsyrer, polyglycerolestere af fedtsyrer, lecithiner og sorbitanmonostearat.
11. Fremgangsmåde til fremstilling af en sammensætning ifølge et hvilket som helst af kravene 5-10, hvilken fremgangsmåde omfatter følgende trin: I) fremstilling af en vandig opløsning eller kolloid opløsning af et modificeret polysaccharid ved en temperatur i intervallet fra 1 til < 100 °C, II) f raseparation af dele af den i trin I) opnåede vandige opløsning eller kolloide opløsning for at opnå en vandig opløsning af et forbedret modificeret polysaccharid, III) eventuelt tilsætning af mindst en vandopløselig excipiens og/eller adjuvans til den i trin I) eller II) fremstillede opløsning, IV) fremstilling af en opløsning eller dispersion af mindst en aktiv bestanddel, fortrinsvis af mindst en fedtopløselig aktiv bestanddel, og/eller et farvestof og eventuelt mindst en fedtopløselig adjuvans og/eller excipiens, V) blanding af de i trin II) til IV) fremstillede opløsninger med hinanden, VI) homogenisering af den således resulterende blanding, VII) eventuelt omdannelse af den i trin VI) opnåede dispersion til et pulver, hvorved de i trin II) (eller trin b)) fraseparerede dele eventuelt tilsættes delvist eller helt under eller før omdannelsen, eventuelt under tilsætning af vand, og VIII) eventuelt tørring af det i trin VII) opnåede pulver, hvor det modificerede polysaccharid er en OSA-stivelse.
12. Fremgangsmåde ifølge krav 11, hvor trin I) og II) udføres som følger: den vandige opløsning eller suspension af det modificerede polysaccharid opvarmes til en temperatur på fra > 30 til < 100 °C (trin I), og derpå køles den til en temperatur på mindre end 30 °C og sedimenteres, mikrofiltreres og/eller ultrafiltreres ved denne lavere temperatur (trin II).
13. Anvendelse af en sammensætning ifølge et hvilket som helst af kravene 5-10 til berigelse, forstærkning og/eller farvning af fødevarer, drikkevarer, dyrefoder, kosmetik eller farmaceutiske sammensætninger.
14. Fødevarer, drikkevarer, dyrefoder, kosmetik og farmaceutiske sammensætninger, som indeholder en sammensætning ifølge et hvilket som helst af kravene 5-10.
DK07703313.2T 2006-02-06 2007-02-06 Sammensætninger af aktive bestanddele DK1981915T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06002420 2006-02-06
EP06002421 2006-02-06
EP06002418 2006-02-06
EP06002419 2006-02-06
PCT/EP2007/001015 WO2007090614A1 (en) 2006-02-06 2007-02-06 Compositions of active ingredients

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DK1981915T3 true DK1981915T3 (da) 2018-08-06

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US (3) US20090105331A1 (da)
EP (2) EP1981915B1 (da)
JP (2) JP5641694B2 (da)
KR (2) KR101517624B1 (da)
DK (1) DK1981915T3 (da)
ES (2) ES2394108T3 (da)
PL (2) PL1981357T3 (da)
TR (1) TR201809592T4 (da)
WO (2) WO2007090610A2 (da)

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US20090105331A1 (en) 2009-04-23
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