DK1937343T3 - System til administration af en farmaceutisk gas til en patient - Google Patents

System til administration af en farmaceutisk gas til en patient Download PDF

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Publication number
DK1937343T3
DK1937343T3 DK06803413.1T DK06803413T DK1937343T3 DK 1937343 T3 DK1937343 T3 DK 1937343T3 DK 06803413 T DK06803413 T DK 06803413T DK 1937343 T3 DK1937343 T3 DK 1937343T3
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Denmark
Prior art keywords
gas
patient
amount
delivered
time
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DK06803413.1T
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English (en)
Inventor
Frederick J Montgomery
Duncan P L Bathe
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Ino Therapeutics Llc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0051—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes with alarm devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0875—Connecting tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
    • A61M2202/0233—Carbon monoxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/42—Rate

Claims (10)

1. System (22) til administration af en terapigas til en patient, hvor terapigassen er mindst én gas, der er udvalgt blandt carbonmonoxid (CO)- og nitrogenoxid (NO)-gas, hvilket system omfatter: et indløbsmiddel (24) til tilkobling til en kilde af terapigas (20) ; et udløbsmiddel (19) til tilkobling til en patientanordning (18) til indførelse af gas i lungerne hos en patient (41); et middel til bestemmelse af den ønskede totalmængde af terapigas, der skal fremføres (12) til patienten over et antal vejrtrækninger; og et gasreguleringssystem til fremførsel af den ønskede totalmængde af terapigas til patientens alveoli over antallet af vejrtrækninger uafhængigt af patientens respirationsmønster.
2. System (22) ifølge krav 1, hvor gasreguleringssystemet inkluderer en central processorenhed (CPU) (40), hvilken CPU regulerer mængden af gas, der fremføres i løbet af én eller flere patientvejrtrækninger, på baggrund af en kendt koncentration af CO- eller NO-gas i bæregassen, indtil den ønskede mængde gas er blevet fremført.
3. System (22) ifølge krav 1, hvor midlet til bestemmelse af den ønskede mængde gas er en indstillingsknap (12) i enhederne (a) masse, (b) masse pr. tidsenhed, (c) mol, (d) mol pr. tidsenhed, (e) masse pr. enhed ideel kropsvægt pr. tidsenhed og et input af ideel kropsvægt, (f) masse pr. enhed ideel kropsvægt og et input af ideel kropsvægt eller (g) masse pr. tidsenhed og et input af tid for varigheden af behandlingen.
4. System (22) ifølge krav 1, hvor gasreguleringssystemet inkluderer en patientsensor (38), der bestemmer respirationshastigheden hos en patient, og hvor gasreguleringssystemet inkluderer en central processorenhed (CPU) (40), der beregner mængden af gas, der skal fremføres pr. vejrtrækning, på baggrund af den ønskede mængde gas, koncentrationen af CO- eller NO-gas i bæregassen og mindst den ene af respirationshastigheden hos patienten og varigheden af behandlingen.
5. System (22) ifølge krav 1, hvor gasreguleringssystemet inkluderer en patientudløsersensor (38), der registrerer begyndelsen af en inspirationscyklus hos en patient, og hvor systemet (22) fremfører den mængde gas, der skal fremføres pr. vejrtrækning i den første halvdel af inspirationstiden, når patientudløsersensoren (38) indikerer begyndelsen af inspirationscyklussen.
6. System (22) ifølge krav 1, der yderligere inkluderer en alarmanordning (42), hvor gasreguleringssystemet aktiverer alarmanordningen (42), når den ønskede mængde af CO- eller N0-gassen er blevet fremført til en patient.
7. System (22) ifølge krav 5, hvor gasreguleringssystemet inkluderer en central processorenhed (CPU) (40), der beregner mængden af terapigas, der skal fremføres pr. vejrtrækning, på baggrund af den ønskede mængde gas, koncentrationen af terapigassen, varigheden af administrationen af terapigassen til patienten og respirationshastigheden for patienten bestemt ved hjælp af patientudløsersensoren (38).
8. System (22) ifølge krav 5, hvor gasreguleringssystemet inkluderer en central processorenhed (CPU) (40), der beregner mængden af terapigas, der skal fremføres pr. vejrtrækning, på baggrund af den ønskede mængde gas, koncentrationen af terapigassen og respirationshastigheden for patienten bestemt ved hjælp af patientudløsersensoren (38).
9. System (22) ifølge krav 7, hvor den centrale processorenhed (CPU (40) genberegner mængden af gas, der skal fremføres pr. vejrtrækning, på baggrund af den ønskede mængde gas, koncentrationen af CO- eller NO-gassen i bæregassen og mindst den ene af respirationshastigheden for patienten og varigheden af behandlingen, efter hver vejrtrækning.
10. System (22) ifølge krav 1, der yderligere omfatter et middel til beregning af antallet af vejrtrækninger, der kræves for fremføring af den ønskede totalmængde af terapigas.
DK06803413.1T 2005-09-21 2006-09-13 System til administration af en farmaceutisk gas til en patient DK1937343T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/231,554 US7523752B2 (en) 2005-09-21 2005-09-21 System and method of administering a pharmaceutical gas to a patient
PCT/US2006/035450 WO2007037975A2 (en) 2005-09-21 2006-09-13 System and method of administering a pharmaceutical gas to a patient

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DK1937343T3 true DK1937343T3 (da) 2016-07-25

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DK06803413.1T DK1937343T3 (da) 2005-09-21 2006-09-13 System til administration af en farmaceutisk gas til en patient
DK18162938.7T DK3372269T3 (da) 2005-09-21 2006-09-13 System til administrering af en farmaceutisk gas til en patient

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US (11) US7523752B2 (da)
EP (3) EP3372269B1 (da)
JP (1) JP4994380B2 (da)
CN (3) CN101312761B (da)
AU (1) AU2006295150B2 (da)
BR (1) BRPI0616155B8 (da)
CA (2) CA2623052C (da)
CY (1) CY1117999T1 (da)
DK (2) DK1937343T3 (da)
ES (3) ES2579432T3 (da)
HK (2) HK1126150A1 (da)
HU (2) HUE057384T2 (da)
LT (1) LT3372269T (da)
MX (2) MX370646B (da)
PL (2) PL1937343T3 (da)
PT (2) PT1937343T (da)
SI (2) SI3372269T1 (da)
WO (1) WO2007037975A2 (da)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE529989C2 (sv) * 2004-09-03 2008-01-29 Ric Investments Llc Gasregulator
FR2875138B1 (fr) 2004-09-15 2008-07-11 Mallinckrodt Dev France Sa Procede de regulation pour un humidificateur chauffant
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US20070181126A1 (en) * 2006-02-08 2007-08-09 Tolmie Craig R Method and apparatus for ventilating a patient with a breathing gas mixture formed from nitric oxide, air, and oxygen
US8485185B2 (en) 2008-06-06 2013-07-16 Covidien Lp Systems and methods for ventilation in proportion to patient effort
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US8393323B2 (en) 2008-09-30 2013-03-12 Covidien Lp Supplemental gas safety system for a breathing assistance system
SI3498328T1 (sl) 2009-05-27 2021-03-31 Mallinckrodt Hospital Products IP Limited Pripomoček za spajanje indeksiranega ventila in sestava posode pod tlakom s pritrdilnim obročem in za linearno sprožitev sestava sprožilnika pri odvajanju tekočin s pripomočkom za reguliranje dovajanja zdravila
JP2011010865A (ja) 2009-06-30 2011-01-20 Ikaria Holdings Inc 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法
DE102010016699A1 (de) * 2010-04-29 2011-11-03 Maquet Gmbh & Co. Kg Verfahren und Vorrichtung zur Applikation mindestens eines medizinischen Gases an einen mit Hilfe eines Beatmungsgeräts beatmeten Patienten
NZ724347A (en) 2011-01-06 2018-03-23 Mallinckrodt Hospital Products Ip Ltd Gas delivery device and system
US8783250B2 (en) 2011-02-27 2014-07-22 Covidien Lp Methods and systems for transitory ventilation support
US8714154B2 (en) 2011-03-30 2014-05-06 Covidien Lp Systems and methods for automatic adjustment of ventilator settings
JP6112757B2 (ja) * 2011-06-17 2017-04-12 フクダ電子株式会社 一酸化炭素投与システム
JP5907675B2 (ja) * 2011-06-17 2016-04-26 フクダ電子株式会社 一酸化炭素投与システム
JP6112756B2 (ja) * 2011-06-17 2017-04-12 フクダ電子株式会社 一酸化炭素投与システム
AU2012335937B2 (en) 2011-11-07 2017-05-25 Mallinckrodt Hospital Products IP Limited Apparatus and method for monitoring nitric oxide delivery
US10426913B2 (en) 2011-11-07 2019-10-01 Mallinckrodt Hospital Products IP Limited Apparatus and method for monitoring nitric oxide delivery
CN102500024B (zh) * 2011-12-01 2014-06-25 于邦仲 一种呼吸机流量检测系统
US8944051B2 (en) 2012-04-05 2015-02-03 Ino Therapeutics Llc Breathing apparatus detection and purging
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
US9032959B2 (en) 2012-12-04 2015-05-19 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US9604026B2 (en) 2013-02-20 2017-03-28 Wisconsin Alumni Research Foundation Medical carbon monoxide delivery system
CA3114977C (en) * 2013-03-13 2023-01-17 Mallinckrodt Hospital Products IP Limited Apparatus and method for monitoring nitric oxide delivery
EP3756714B1 (en) * 2013-03-15 2023-05-17 Mallinckrodt Hospital Products IP Limited Therapeutic gas delivery device with pulsed and continuous flow control
MX364174B (es) 2013-03-15 2019-04-15 Mallinckrodt Hospital Products Ip Ltd Dispositivo para el suministro de gas terapeutico con control de flujo pulsatil y continuo.
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
US10667510B2 (en) 2013-03-15 2020-06-02 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
US10342948B2 (en) 2013-03-18 2019-07-09 Mallinckrodt Hospital Products IP Limited Therapeutic gas delivery device with pulsed and continuous flow control
CN103263715B (zh) * 2013-05-24 2015-12-02 史源 一氧化碳吸入仪
US10512741B2 (en) 2013-09-13 2019-12-24 Mallinckrodt Hospital Products IP Limited Clinical decision support system and methods
US20150114395A1 (en) * 2013-10-29 2015-04-30 General Electric Company Method and arrangement for determining a ventilation need specific for a patient
CA2936490C (en) 2014-01-10 2022-10-04 Ino Therapeutics Llc Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
US10188822B2 (en) * 2014-03-13 2019-01-29 Mallinckrodt Hospital Products IP Limited Gas delivery device and system for use in magnetic resonance imaging
US10226592B2 (en) 2014-04-01 2019-03-12 Mallinckrodt Hospital Product Ip Limited Systems and method for delivery of therapeutic gas to patients in need thereof using enhanced breathing circuit gas (BCG) flow measurement
TW201618795A (zh) 2014-04-15 2016-06-01 波泰里斯股份有限公司 用以改良器官功能及延長器官移植物壽命之系統及方法
US10071213B2 (en) 2014-05-02 2018-09-11 Mallinckrodt Hospital Products IP Limited Systems and method for delivery of therapeutic gas to patients, in need thereof, receiving breathing gas from a ventilator that varies at least pressure and/or flow using enhanced therapeutic gas (NO) flow measurement
MX2021007817A (es) * 2014-05-09 2023-01-10 Mallinckrodt Hospital Products Ip Ltd Sistemas y metodos para el manejo de fuente de gas inteligente y/o sistemas y metodos para suministro de gas terapeutico y/o verificacion de desempe?o mejorada para suministro de gas terapeutico.
US10525226B2 (en) * 2014-05-14 2020-01-07 Mallinckrodt Hospital Products IP Limited Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
US10384031B1 (en) 2014-06-20 2019-08-20 Mallinckrodt Hospital Products IP Limited Systems and methods for manufacturing and safety of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
US9808591B2 (en) 2014-08-15 2017-11-07 Covidien Lp Methods and systems for breath delivery synchronization
US10758703B2 (en) 2014-10-17 2020-09-01 Mallinckrodt Hospital Products IP Limited Systems and methods for providing a pulse of a therapeutic gas with a desired flow profile to maximize therapeutic effectiveness
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
EP3277351B1 (en) 2015-04-02 2019-06-05 Hill-Rom Services PTE. LTD. Manifold for respiratory device
WO2016196837A1 (en) * 2015-06-03 2016-12-08 The Regents Of The University Of California Resuscitation and ventilation monitor
KR20180095504A (ko) 2015-10-01 2018-08-27 말린크로트 하스피탈 프로덕츠 아이피 리미티드 흡입 치료 가스로 고농도 no를 확산시키는 장치 및 방법
PL3410927T3 (pl) 2016-02-02 2022-05-02 Mallinckrodt Pharmaceuticals Ireland Limited Kompensacja zakłóceń w pomiarze przepływu gazu oddechowego
CA3012180A1 (en) 2016-02-12 2017-08-17 Mallinckrodt Hospital Products IP Limited Use and monitoring of inhaled nitric oxide with left ventricular assist devices
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
AU2018223826B2 (en) 2017-02-27 2019-11-07 Third Pole, Inc. Systems and methods for generating nitric oxide
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
US11478594B2 (en) 2018-05-14 2022-10-25 Covidien Lp Systems and methods for respiratory effort detection utilizing signal distortion
US11752287B2 (en) 2018-10-03 2023-09-12 Covidien Lp Systems and methods for automatic cycling or cycling detection
GB2581999B (en) * 2019-03-07 2023-01-04 Bpr Medical Ltd Gas flow alarm
EP3969415A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. ELECTRODES FOR NITRIC OXIDE GENERATION
JP2022532654A (ja) 2019-05-15 2022-07-15 サード ポール，インコーポレイテッド 一酸化窒素を生成するシステム及び方法
ES2898269T3 (es) * 2019-05-23 2022-03-04 Air Liquide Sistema de bolsa de reanimación con una unidad de control de gas
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
EP4065133A2 (en) 2019-11-25 2022-10-05 Beyond Air, Inc. Methods employing gaseous nitric oxide for inhibiting tumor growth
CN111135406B (zh) * 2020-01-10 2023-08-08 宁波戴维医疗器械股份有限公司 一种高频呼吸机
JP2023512444A (ja) 2020-01-11 2023-03-27 サード ポール，インコーポレイテッド 湿度制御を用いた酸化窒素生成のためのシステムおよび方法
WO2021231363A1 (en) * 2020-05-11 2021-11-18 The United States Of America As Represented By The Secretary Of The Navy Medical ventilator and method of use
WO2021258025A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11369763B2 (en) * 2020-07-31 2022-06-28 Soco International Llc Respiratory ventilatory device and method of operating same
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3802417A (en) * 1968-12-21 1974-04-09 V Lang Device for combined monitoring and stimulation of respiration
JPS6294175A (ja) * 1985-10-18 1987-04-30 鳥取大学長 呼吸同調式ガス吹送装置および方法
DE69133575T2 (de) * 1990-12-05 2008-04-17 The General Hospital Corp., Boston Verwendung von NO zur Behandlung der persistenten pulmonaren Hypertonie des Neugeborenen
US5319355A (en) * 1991-03-06 1994-06-07 Russek Linda G Alarm for patient monitor and life support equipment system
GB2279014B (en) 1993-06-02 1997-07-16 Niall Keaney Device for controlling delivery of respiratory drugs
GB9320978D0 (en) 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) * 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
JP2786808B2 (ja) 1994-02-10 1998-08-13 忠道 目黒 気相系呼吸機能の測定方法および測定結果を用いた気相系呼吸機能の健康管理方法
JP3142716B2 (ja) * 1994-04-28 2001-03-07 裕一 石部 呼吸器への一酸化窒素の供給装置
AU720686B2 (en) * 1996-04-05 2000-06-08 General Hospital Corporation, The Treatment of a hemoglobinopathy
US5732693A (en) 1996-10-02 1998-03-31 Ohmeda Inc. Pause control of nitric oxide therapy
US5752504A (en) 1996-12-13 1998-05-19 Ohmeda Inc. System for monitoring therapy during calibration
CN1179331A (zh) * 1996-10-11 1998-04-22 鲍辛纳克·乔治斯 呼吸辅助设备
JPH10179742A (ja) * 1996-12-25 1998-07-07 Sumitomo Seika Chem Co Ltd 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法
ATE320829T1 (de) 1997-01-17 2006-04-15 Ino Therapeutics Gmbh Gesteuertes gasversorgungssystem
US5918596A (en) 1997-04-22 1999-07-06 Instrumentarium Corp. Special gas dose delivery apparatus for respiration equipment
US6125846A (en) 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
US6164276A (en) * 1997-05-16 2000-12-26 Datex-Ohmeda, Inc. Accurate dose nitric oxide pulse delivery device with monitoring and alarms
US6371114B1 (en) 1998-07-24 2002-04-16 Minnesota Innovative Technologies & Instruments Corporation Control device for supplying supplemental respiratory oxygen
US6109260A (en) * 1998-02-18 2000-08-29 Datex-Ohmeda, Inc. Nitric oxide administration device with timed pulse
US6089229A (en) * 1998-05-26 2000-07-18 Datex-Ohmeda, Inc. High concentration no pulse delivery device
JP2000024110A (ja) * 1998-07-16 2000-01-25 Teijin Ltd 呼吸同調型気体供給装置
FI110065B (fi) * 1998-12-08 2002-11-29 Instrumentarium Oyj Sovitelma takaisinkytketyn säätöjärjestelmän yhteydessä
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
CN2368059Y (zh) * 1999-04-21 2000-03-08 莫绪明 一氧化氮气体吸入流量控制仪
WO2001021239A1 (en) * 1999-09-22 2001-03-29 Instrumentarium Corporation A method to improve oxygenation in subjects suffering impaierd oxygenation
SE9903467D0 (sv) * 1999-09-24 1999-09-24 Siemens Elema Ab Feedback control of mechanical breathing aid gas flow
US7516742B2 (en) 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6581599B1 (en) 1999-11-24 2003-06-24 Sensormedics Corporation Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients
CN2439288Y (zh) 2000-07-27 2001-07-18 中国人民解放军第二军医大学南京军医学院 一氧化氮高频喷射通气治疗仪
US6668828B1 (en) * 2000-10-16 2003-12-30 Pulmonox Technologies Corporations System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient
JP2002143305A (ja) * 2000-11-14 2002-05-21 Gunma Koike:Kk 呼吸同調型酸素供給装置
DE60202677T2 (de) * 2001-05-25 2005-12-29 Medtronic, Inc., Minneapolis Implantierbare medizinische vorrichtung mit kontrollierter freigabe von gasförmigen mitteln
CA2351217C (en) * 2001-06-19 2008-12-02 Teijin Limited An apparatus for supplying a therapeutic oxygen gas
DK1642608T3 (da) * 2001-12-06 2011-08-01 Carefusion 303 Inc CO2-overvåget lægemiddelinfusionssystem
BRPI0307673A2 (pt) * 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
US20030189492A1 (en) * 2002-04-04 2003-10-09 Harvie Mark R. Monitoring, alarm and automatic adjustment system for users of oxygen and compressed air
MXPA04010243A (es) * 2002-04-15 2005-07-05 Univ Pittsburgh Metodos para tratar ileo.
US6909912B2 (en) 2002-06-20 2005-06-21 University Of Florida Non-invasive perfusion monitor and system, specially configured oximeter probes, methods of using same, and covers for probes
DE10230165A1 (de) * 2002-07-04 2004-01-15 Ino Therapeutics Gmbh Verfahren und Vorrichtung zur Administration von Kohlenmonoxid
EP1558084A4 (en) * 2002-11-07 2008-04-30 Univ Pittsburgh TREATMENT OF HEMORRHAGIC SHOCK
CN2584208Y (zh) * 2003-01-22 2003-11-05 陈延航 主动按需脉冲吸氧控制器
DE10306766A1 (de) 2003-02-18 2004-08-26 Ino Therapeutics Gmbh Dosierte Abgabe eines therapeutischen Gases
DE10321448A1 (de) * 2003-05-13 2004-12-02 Ino Therapeutics Gmbh Verfahren und Vorrichtung zur kontrollierten Zumischung eines Gases oder Gasgemisches zu einem Gas(gemisch)strom
EP1755715A4 (en) 2004-05-11 2010-03-24 Sensormedics Corp INTERMITTENT DETERMINATION OF GASEOUS NITRIC OXIDE
US7690378B1 (en) * 2004-07-21 2010-04-06 Pacesetter, Inc. Methods, systems and devices for monitoring respiratory disorders
US7370651B2 (en) 2005-04-01 2008-05-13 Ric Investments, Llc Gas conserving device
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US7305988B2 (en) 2005-12-22 2007-12-11 The General Electric Company Integrated ventilator nasal trigger and gas monitoring system
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US20100175695A1 (en) 2009-01-12 2010-07-15 Mindray Ds Usa, Inc. Auxiliary gas mixing in an anesthesia system
JP2011010865A (ja) 2009-06-30 2011-01-20 Ikaria Holdings Inc 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法
NZ724347A (en) 2011-01-06 2018-03-23 Mallinckrodt Hospital Products Ip Ltd Gas delivery device and system

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