BRPI0307673A2 - métodos de tratar doença vascular. - Google Patents
métodos de tratar doença vascular.Info
- Publication number
- BRPI0307673A2 BRPI0307673A2 BRPI0307673A BR0307673A BRPI0307673A2 BR PI0307673 A2 BRPI0307673 A2 BR PI0307673A2 BR PI0307673 A BRPI0307673 A BR PI0307673A BR 0307673 A BR0307673 A BR 0307673A BR PI0307673 A2 BRPI0307673 A2 BR PI0307673A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- vascular disease
- treating vascular
- treating
- disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35671802P | 2002-02-13 | 2002-02-13 | |
PCT/US2003/004665 WO2003072024A2 (en) | 2002-02-13 | 2003-02-13 | Methods of treating vascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0307673A2 true BRPI0307673A2 (pt) | 2016-11-08 |
Family
ID=27765943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0307673A BRPI0307673A2 (pt) | 2002-02-13 | 2003-02-13 | métodos de tratar doença vascular. |
Country Status (15)
Country | Link |
---|---|
US (2) | US7364757B2 (pt) |
EP (1) | EP1480658B1 (pt) |
JP (1) | JP2005525848A (pt) |
KR (1) | KR20040096571A (pt) |
CN (1) | CN100393323C (pt) |
AU (1) | AU2003211102B2 (pt) |
BR (1) | BRPI0307673A2 (pt) |
CA (1) | CA2475963A1 (pt) |
CO (1) | CO5611156A2 (pt) |
EA (1) | EA200401070A1 (pt) |
MX (1) | MXPA04007896A (pt) |
NO (1) | NO20034590L (pt) |
SG (1) | SG148850A1 (pt) |
UA (1) | UA86344C2 (pt) |
WO (1) | WO2003072024A2 (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7678390B2 (en) | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
KR20040032115A (ko) * | 2001-06-21 | 2004-04-14 | 베쓰 이스라엘 디코니스 메디칼 센터 인크 | 조직 및 장기 이식 결과의 개선 및 아폽토시스의 억제에사용되는 일산화탄소 |
US7968605B2 (en) * | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
EP1476168A2 (en) | 2002-02-04 | 2004-11-17 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
EA200401070A1 (ru) * | 2002-02-13 | 2005-02-24 | Бет Изрейэл Диконисс Медикал Сентер, Инк. | Способы лечения сосудистых заболеваний |
CA2482260A1 (en) | 2002-04-15 | 2003-10-30 | Beth Israel Deaconess Medical Center Inc. | Use of heme oxygenase-1 and products of heme degradation |
UA86570C2 (ru) | 2002-04-15 | 2009-05-12 | Юниверсити Оф Питтсбург Оф Дзе Коммонвелз Систем Оф Хайер Эдьюкейшн | Способ лечения некротизирующего энтероколита |
US7687079B2 (en) | 2002-04-15 | 2010-03-30 | University of Pittsburgh of the Commonwealth System of Higher Education Yale University | Methods of treating ileus |
ES2372273T3 (es) | 2002-05-17 | 2012-01-17 | Yale University | Métodos de tratamiento de la hepatitis. |
UA87438C2 (ru) * | 2002-06-05 | 2009-07-27 | Йельский Университет | Способы лечения или профилактики рака, способ проведения хирургической операции по удалению рака и применения монооксида углерода |
MXPA04012863A (es) * | 2002-06-21 | 2005-03-31 | Univ Pittsburgh | Uso farmaceutico de oxido nitrico, heme oxigenasa-1 y productos de degradacion de heme. |
EA200500782A1 (ru) * | 2002-11-07 | 2005-10-27 | Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн | Лечение геморрагического шока |
GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
US20070207217A1 (en) * | 2003-02-03 | 2007-09-06 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Method for treating a mammal by administration of a compound having the ability to release CO |
US20040236279A1 (en) * | 2003-05-22 | 2004-11-25 | Atrium Medical Corp. | Gaseous therapeutic agent delivery |
EP2363022A3 (en) | 2003-10-22 | 2011-12-21 | Fred Hutchinson Cancer Research Center | Use of oxygen antagonists for the therapeutic treatment of mammals |
WO2006024491A1 (en) * | 2004-08-30 | 2006-03-09 | Interstitial Therapeutics | Methods and compositions for the treatment of cell proliferation |
US8893717B2 (en) | 2005-09-21 | 2014-11-25 | Ino Therapeutics Llc | Systems and methods of administering a pharmaceutical gas to a patient |
US7523752B2 (en) | 2005-09-21 | 2009-04-28 | Ino Therapeutics, Llc | System and method of administering a pharmaceutical gas to a patient |
GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
US20080160064A1 (en) * | 2006-12-22 | 2008-07-03 | Capelli Christopher C | Devices and methods for inhibiting fibrosis |
JP5639645B2 (ja) | 2009-05-27 | 2014-12-10 | イノ セラピューティクス エルエルシー | 指標付弁と襟部を有する加圧容器組立体を係合するため、かつ薬物送達を調整するための装置と流体連通したプランジャ組立体により直線的に作動させるための装置および方法 |
CA2671029A1 (en) | 2009-06-30 | 2010-12-30 | James S. Baldassarre | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
HUP1000243A2 (en) | 2010-05-06 | 2012-01-30 | Avidin Kft | 8-hidroxy-quinoline derivatives |
US8778413B2 (en) * | 2010-05-14 | 2014-07-15 | Ikaria, Inc. | Dosing regimens and methods of treatment using carbon monoxide |
EP2663193B1 (en) * | 2011-01-14 | 2019-05-08 | Children's Hospital Los Angeles | Solution of carbon monoxide for treatment of disease, including sickle cell disease |
EP2699242B1 (en) | 2011-04-19 | 2017-11-01 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
JP6134710B2 (ja) | 2011-07-21 | 2017-05-24 | アルファーマ インコーポレイテッドAlfama,Inc. | 一酸化ルテニウム放出分子およびその使用 |
WO2013022946A1 (en) | 2011-08-09 | 2013-02-14 | Beth Israel Deaconess Medical Center, Inc. | Methods of treating dna damage |
JP6245613B2 (ja) | 2012-03-15 | 2017-12-13 | マリンクロット ホスピタル プロダクツ アイピー リミテッド | 高濃度の一酸化窒素の投与法 |
US20140272924A1 (en) * | 2013-03-14 | 2014-09-18 | Ganogen, Inc. | Transplantation and growth of human fetal organs in non-human animal hosts |
TW201618795A (zh) | 2014-04-15 | 2016-06-01 | 波泰里斯股份有限公司 | 用以改良器官功能及延長器官移植物壽命之系統及方法 |
JP6591203B2 (ja) * | 2015-06-01 | 2019-10-16 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置 |
CN113289074A (zh) * | 2020-02-24 | 2021-08-24 | 张建强 | 一种新型的药物涂层支架及其制备方法 |
US20230398141A1 (en) * | 2020-09-08 | 2023-12-14 | The Brigham And Women's Hospital, Inc. | Therapeutic carbon monoxide formulations |
Family Cites Families (60)
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US4053590A (en) * | 1975-02-27 | 1977-10-11 | Alza Corporation | Compositions of matter comprising macromolecular hemoglobin |
US4264739A (en) * | 1979-01-05 | 1981-04-28 | Merck & Co., Inc. | Sparger for cell culture system |
JPS5679957A (en) | 1979-12-05 | 1981-06-30 | Sogo Seibutsu Igaku Kenkyusho:Kk | Erucinia enterocolitica polysaccharide sensitizing blood cell and method of detecting erucinia enterocolitica polysaccharide antibody using this |
US5240912A (en) * | 1983-05-09 | 1993-08-31 | Todaro George J | Transforming growth factor (TGF) peptides |
US4979939A (en) * | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
US5084380A (en) * | 1985-01-29 | 1992-01-28 | Applied Biotechnology | Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins |
US5449665A (en) * | 1985-09-24 | 1995-09-12 | Item Development Aktiebolag | Continuous intravenous infusion of adenosine to human patients undergoing percutaneous transluminal angioplasty |
DE3739650C1 (de) * | 1987-11-23 | 1989-05-24 | Immuno Ag | Fermenter zum Zuechten von Zellkulturen |
US5674192A (en) | 1990-12-28 | 1997-10-07 | Boston Scientific Corporation | Drug delivery |
US5180366A (en) * | 1990-10-10 | 1993-01-19 | Woods W T | Apparatus and method for angioplasty and for preventing re-stenosis |
US5792325A (en) * | 1990-11-15 | 1998-08-11 | Richardson, Jr.; William H. | Electric arc material processing system |
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US5293875A (en) * | 1992-06-16 | 1994-03-15 | Natus Medical Incorporated | In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods |
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US5523092A (en) * | 1993-04-14 | 1996-06-04 | Emory University | Device for local drug delivery and methods for using the same |
US5985307A (en) * | 1993-04-14 | 1999-11-16 | Emory University | Device and method for non-occlusive localized drug delivery |
US5763431A (en) * | 1993-08-20 | 1998-06-09 | Jackson; Meyer B. | Method for regulating neuropeptide hormone secretion |
US5588962A (en) * | 1994-03-29 | 1996-12-31 | Boston Scientific Corporation | Drug treatment of diseased sites deep within the body |
DE4421433C1 (de) * | 1994-06-18 | 1995-06-08 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung |
US5476764A (en) * | 1994-09-16 | 1995-12-19 | The Regents Of The University Of California | Method using CO for extending the useful shelf-life of refrigerated red blood cells |
US6066333A (en) * | 1994-09-22 | 2000-05-23 | William Harvey Research Limited | Pharmaceutical control of inflammation |
JPH0898893A (ja) * | 1994-09-29 | 1996-04-16 | Terumo Corp | 薬剤投与カテーテル |
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US5914316A (en) * | 1994-12-16 | 1999-06-22 | Washington University | Method of inhibiting intimal hyperplasia |
US5712293A (en) * | 1995-06-07 | 1998-01-27 | Sepracor, Inc. | Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride |
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FR2735382B1 (fr) * | 1995-06-15 | 1997-07-25 | Air Liquide | Installation de production de monoxyde de carbone incorporant une unite de separation cryogenique |
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ATE293458T1 (de) * | 1996-08-23 | 2005-05-15 | Algos Pharm Corp | Antikonvulsive mitteln enthaltende zubereitung zur behandlung von neuropathischen schmerzen |
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US6315995B1 (en) | 1996-09-27 | 2001-11-13 | The Trustees Of Columbia University In The City Of New York | Methods for treating an ischemic disorder and improving stroke outcome |
US6316403B1 (en) * | 1996-09-27 | 2001-11-13 | The Trustees Of Columbia University In The City Of New York | Methods for treating an ischemic disorder and improving stroke outcome |
US8128963B2 (en) * | 1996-09-27 | 2012-03-06 | The Trustees Of Columbia University In The City Of New York | Methods for treating ischemic disorders using carbon monoxide |
ATE358492T1 (de) * | 1996-09-27 | 2007-04-15 | Univ Columbia | Behandlung einer ischämischen störung und zur verbesserung des infarktergebnis |
US6436365B2 (en) * | 1997-09-23 | 2002-08-20 | Schering Aktiengesellschaft | Process for therapeutic treatment of proliferative diseases |
US6251418B1 (en) * | 1997-12-18 | 2001-06-26 | C.R. Bard, Inc. | Systems and methods for local delivery of an agent |
BR9908811A (pt) | 1998-03-16 | 2000-12-05 | Celgene Corp | Composto, composição farmacêutica e seu uso no tratamento de mamìferos |
US6450989B2 (en) * | 1998-04-27 | 2002-09-17 | Artemis Medical, Inc. | Dilating and support apparatus with disease inhibitors and methods for use |
JP4023919B2 (ja) * | 1998-07-21 | 2007-12-19 | 株式会社フクダ産業 | 肺機能検査装置 |
US6203991B1 (en) * | 1998-08-21 | 2001-03-20 | The Regents Of The University Of Michigan | Inhibition of smooth muscle cell migration by heme oxygenase I |
US20050250688A1 (en) * | 1999-04-01 | 2005-11-10 | The Trustees Of Columbia University In The City Of New York | Methods for treating an ischemic disorder and improving stroke outcome |
DE19932824A1 (de) * | 1999-07-14 | 2001-03-08 | Nordischer Maschinenbau | Verfahren und Vorrichtung zum Ausrichten eines toten Fisches |
JP2001082698A (ja) * | 1999-09-16 | 2001-03-30 | Teijin Ltd | 医療用酸素ボンベ |
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US6508784B1 (en) * | 2000-05-19 | 2003-01-21 | Yan-Ho Shu | Balloon catheter having adjustable centering capabilities and methods thereof |
FR2812197B1 (fr) | 2000-07-27 | 2003-01-03 | Air Liquide Sante Int | Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches |
FR2816212A1 (fr) | 2000-11-03 | 2002-05-10 | Air Liquide Sante Int | Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire |
US20040197271A1 (en) * | 2001-03-20 | 2004-10-07 | Kunka Robert Leonard | Inhalation drug combinations |
CN1507348A (zh) | 2001-03-30 | 2004-06-23 | ɣ����ҽҩ��˾ | 用于治疗血管性、炎性和免疫疾病的一氧化碳生成性组合物 |
GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
EP1395241B9 (en) * | 2001-05-25 | 2005-06-15 | Medtronic, Inc. | Implantable medical device with controllable gaseous agent release system |
KR20040032115A (ko) | 2001-06-21 | 2004-04-14 | 베쓰 이스라엘 디코니스 메디칼 센터 인크 | 조직 및 장기 이식 결과의 개선 및 아폽토시스의 억제에사용되는 일산화탄소 |
EP1476168A2 (en) * | 2002-02-04 | 2004-11-17 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
EA200401070A1 (ru) * | 2002-02-13 | 2005-02-24 | Бет Изрейэл Диконисс Медикал Сентер, Инк. | Способы лечения сосудистых заболеваний |
CA2482260A1 (en) * | 2002-04-15 | 2003-10-30 | Beth Israel Deaconess Medical Center Inc. | Use of heme oxygenase-1 and products of heme degradation |
DE10230165A1 (de) | 2002-07-04 | 2004-01-15 | Ino Therapeutics Gmbh | Verfahren und Vorrichtung zur Administration von Kohlenmonoxid |
-
2003
- 2003-02-13 EA EA200401070A patent/EA200401070A1/ru unknown
- 2003-02-13 CA CA002475963A patent/CA2475963A1/en not_active Abandoned
- 2003-02-13 SG SG200605472-0A patent/SG148850A1/en unknown
- 2003-02-13 KR KR10-2004-7012581A patent/KR20040096571A/ko not_active Application Discontinuation
- 2003-02-13 EP EP03743140.0A patent/EP1480658B1/en not_active Expired - Lifetime
- 2003-02-13 AU AU2003211102A patent/AU2003211102B2/en not_active Ceased
- 2003-02-13 CN CNB038083523A patent/CN100393323C/zh not_active Expired - Fee Related
- 2003-02-13 JP JP2003570771A patent/JP2005525848A/ja active Pending
- 2003-02-13 US US10/367,277 patent/US7364757B2/en not_active Expired - Lifetime
- 2003-02-13 UA UA20040907416A patent/UA86344C2/ru unknown
- 2003-02-13 MX MXPA04007896A patent/MXPA04007896A/es active IP Right Grant
- 2003-02-13 WO PCT/US2003/004665 patent/WO2003072024A2/en active Application Filing
- 2003-02-13 BR BRPI0307673A patent/BRPI0307673A2/pt not_active IP Right Cessation
- 2003-10-13 NO NO20034590A patent/NO20034590L/no not_active Application Discontinuation
-
2004
- 2004-08-30 CO CO04084713A patent/CO5611156A2/es not_active Application Discontinuation
-
2008
- 2008-03-18 US US12/050,826 patent/US7691416B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN100393323C (zh) | 2008-06-11 |
US20080167609A1 (en) | 2008-07-10 |
KR20040096571A (ko) | 2004-11-16 |
CA2475963A1 (en) | 2003-09-04 |
US7691416B2 (en) | 2010-04-06 |
EA200401070A1 (ru) | 2005-02-24 |
AU2003211102B2 (en) | 2010-03-04 |
WO2003072024A3 (en) | 2004-02-26 |
US20030219496A1 (en) | 2003-11-27 |
EP1480658A4 (en) | 2005-03-16 |
CN1646146A (zh) | 2005-07-27 |
US7364757B2 (en) | 2008-04-29 |
UA86344C2 (ru) | 2009-04-27 |
JP2005525848A (ja) | 2005-09-02 |
WO2003072024A2 (en) | 2003-09-04 |
SG148850A1 (en) | 2009-01-29 |
CO5611156A2 (es) | 2006-02-28 |
EP1480658A2 (en) | 2004-12-01 |
MXPA04007896A (es) | 2005-06-17 |
NO20034590D0 (no) | 2003-10-13 |
AU2003211102A1 (en) | 2003-09-09 |
NO20034590L (no) | 2003-12-12 |
EP1480658B1 (en) | 2017-01-25 |
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