DK1917253T3 - Fremgangsmåde til fremstilling af betamimetika - Google Patents
Fremgangsmåde til fremstilling af betamimetika Download PDFInfo
- Publication number
- DK1917253T3 DK1917253T3 DK06778214T DK06778214T DK1917253T3 DK 1917253 T3 DK1917253 T3 DK 1917253T3 DK 06778214 T DK06778214 T DK 06778214T DK 06778214 T DK06778214 T DK 06778214T DK 1917253 T3 DK1917253 T3 DK 1917253T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- beta mimetics
- mimetics
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05107470 | 2005-08-15 | ||
PCT/EP2006/065217 WO2007020227A1 (de) | 2005-08-15 | 2006-08-10 | Verfahren zur herstellung von betamimetika |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1917253T3 true DK1917253T3 (da) | 2015-03-30 |
Family
ID=37198936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06778214T DK1917253T3 (da) | 2005-08-15 | 2006-08-10 | Fremgangsmåde til fremstilling af betamimetika |
Country Status (21)
Country | Link |
---|---|
US (2) | US20070088160A1 (da) |
EP (1) | EP1917253B1 (da) |
JP (1) | JP5270343B2 (da) |
KR (1) | KR101360803B1 (da) |
CN (1) | CN101208316B (da) |
AR (1) | AR056456A1 (da) |
AU (1) | AU2006281449B2 (da) |
BR (1) | BRPI0614410A2 (da) |
CA (1) | CA2619402C (da) |
DK (1) | DK1917253T3 (da) |
ES (1) | ES2530991T3 (da) |
IL (1) | IL189460A (da) |
MX (1) | MX2008001976A (da) |
NZ (1) | NZ566577A (da) |
PE (1) | PE20070418A1 (da) |
PL (1) | PL1917253T3 (da) |
RU (1) | RU2412176C2 (da) |
TW (1) | TWI412523B (da) |
UY (1) | UY29742A1 (da) |
WO (1) | WO2007020227A1 (da) |
ZA (1) | ZA200710049B (da) |
Families Citing this family (23)
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US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
PL1917253T3 (pl) * | 2005-08-15 | 2015-06-30 | Boehringer Ingelheim Int | Sposób wytwarzania betamimetyków |
US20100022770A1 (en) * | 2007-01-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of beta mimetics |
CN101704756B (zh) * | 2009-11-20 | 2017-12-05 | 大连九信精细化工有限公司 | 1—(4—氟苯基)—2—甲基—2—丙胺的合成方法 |
WO2013113787A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113720A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113773A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
CN104220427A (zh) | 2012-02-03 | 2014-12-17 | 巴斯夫欧洲公司 | 杀真菌嘧啶化合物 |
CN104220428A (zh) | 2012-02-03 | 2014-12-17 | 巴斯夫欧洲公司 | 杀真菌嘧啶化合物 |
WO2013113716A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113778A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113776A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
EP2906218B1 (en) | 2012-10-09 | 2016-12-14 | Boehringer Ingelheim International GmbH | Beta-2-adrenoceptor agonist for the treatment of cough |
WO2016038628A2 (en) * | 2014-09-09 | 2016-03-17 | Reddy G Pratap | A process for preparing olodaterol and intermediates thereof |
JP2019536812A (ja) | 2016-12-12 | 2019-12-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | オロダテロールとの同時投与による間質性肺疾患の処置方法に使用するためのニンテダニブ |
ES2900283T3 (es) | 2016-12-20 | 2022-03-16 | Inke Sa | Proceso mejorado para la fabricación de clorhidrato de (R)-6-hidroxi-8-[1-hidroxi-2-[2-(4-metoxifenil)-1,1-dimetiletilaminoetil]-2H-1,4-benzoxazin-3(4H)-ona |
CN109096218B (zh) * | 2018-08-06 | 2020-10-27 | 上海方予健康医药科技有限公司 | 盐酸奥达特罗晶型a及其制备方法 |
CN108997248B (zh) * | 2018-08-06 | 2023-08-01 | 上海方予健康医药科技有限公司 | 盐酸奥达特罗晶型b及其制备方法 |
CN112592323B (zh) * | 2020-06-11 | 2022-07-01 | 上海谷森医药有限公司 | 奥达特罗及其盐的制备方法 |
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-
2006
- 2006-08-10 PL PL06778214T patent/PL1917253T3/pl unknown
- 2006-08-10 JP JP2008526484A patent/JP5270343B2/ja active Active
- 2006-08-10 BR BRPI0614410-1A patent/BRPI0614410A2/pt not_active Application Discontinuation
- 2006-08-10 RU RU2008109650/04A patent/RU2412176C2/ru active
- 2006-08-10 EP EP06778214.4A patent/EP1917253B1/de active Active
- 2006-08-10 AU AU2006281449A patent/AU2006281449B2/en active Active
- 2006-08-10 KR KR1020087006338A patent/KR101360803B1/ko active IP Right Grant
- 2006-08-10 CA CA2619402A patent/CA2619402C/en active Active
- 2006-08-10 DK DK06778214T patent/DK1917253T3/da active
- 2006-08-10 WO PCT/EP2006/065217 patent/WO2007020227A1/de active Application Filing
- 2006-08-10 US US11/463,703 patent/US20070088160A1/en not_active Abandoned
- 2006-08-10 MX MX2008001976A patent/MX2008001976A/es active IP Right Grant
- 2006-08-10 CN CN2006800232661A patent/CN101208316B/zh active Active
- 2006-08-10 NZ NZ566577A patent/NZ566577A/en unknown
- 2006-08-10 ES ES06778214T patent/ES2530991T3/es active Active
- 2006-08-11 PE PE2006000982A patent/PE20070418A1/es not_active Application Discontinuation
- 2006-08-11 UY UY29742A patent/UY29742A1/es not_active Application Discontinuation
- 2006-08-11 AR ARP060103519A patent/AR056456A1/es active IP Right Grant
- 2006-08-14 TW TW095129785A patent/TWI412523B/zh active
-
2007
- 2007-11-21 ZA ZA200710049A patent/ZA200710049B/xx unknown
-
2008
- 2008-02-12 IL IL189460A patent/IL189460A/en not_active IP Right Cessation
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2011
- 2011-02-07 US US13/021,946 patent/US8420809B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2006281449B2 (en) | 2013-01-31 |
KR101360803B1 (ko) | 2014-02-11 |
TWI412523B (zh) | 2013-10-21 |
AR056456A1 (es) | 2007-10-10 |
ZA200710049B (en) | 2008-11-26 |
AU2006281449A1 (en) | 2007-02-22 |
MX2008001976A (es) | 2008-03-25 |
CN101208316A (zh) | 2008-06-25 |
RU2008109650A (ru) | 2009-09-27 |
CN101208316B (zh) | 2012-05-09 |
US8420809B2 (en) | 2013-04-16 |
EP1917253B1 (de) | 2015-01-07 |
RU2412176C2 (ru) | 2011-02-20 |
TW200800925A (en) | 2008-01-01 |
CA2619402C (en) | 2015-02-03 |
ES2530991T3 (es) | 2015-03-09 |
EP1917253A1 (de) | 2008-05-07 |
BRPI0614410A2 (pt) | 2011-03-29 |
PL1917253T3 (pl) | 2015-06-30 |
PE20070418A1 (es) | 2007-05-28 |
JP2009504708A (ja) | 2009-02-05 |
KR20080049049A (ko) | 2008-06-03 |
IL189460A (en) | 2013-08-29 |
JP5270343B2 (ja) | 2013-08-21 |
US20070088160A1 (en) | 2007-04-19 |
UY29742A1 (es) | 2007-03-30 |
NZ566577A (en) | 2011-04-29 |
US20110124859A1 (en) | 2011-05-26 |
WO2007020227A1 (de) | 2007-02-22 |
CA2619402A1 (en) | 2007-02-22 |
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