DK1898914T3 - Quinolinderivater som antibakterielle midler - Google Patents

Quinolinderivater som antibakterielle midler

Info

Publication number
DK1898914T3
DK1898914T3 DK06763889.0T DK06763889T DK1898914T3 DK 1898914 T3 DK1898914 T3 DK 1898914T3 DK 06763889 T DK06763889 T DK 06763889T DK 1898914 T3 DK1898914 T3 DK 1898914T3
Authority
DK
Denmark
Prior art keywords
antibacterial agents
quinoline derivatives
quinoline
derivatives
antibacterial
Prior art date
Application number
DK06763889.0T
Other languages
Danish (da)
English (en)
Inventor
Koenraad J L M Andries
Anil Koul
Magali M S Motte
Leo J J Backx
Lieven Meerpoel
Jerome E G Guillemont
David F A Lancois
Ismet Dorange
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34940244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1898914(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1898914T3 publication Critical patent/DK1898914T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK06763889.0T 2005-06-28 2006-06-26 Quinolinderivater som antibakterielle midler DK1898914T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105762 2005-06-28
PCT/EP2006/063553 WO2007000435A1 (en) 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
DK1898914T3 true DK1898914T3 (da) 2012-11-26

Family

ID=34940244

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06763889.0T DK1898914T3 (da) 2005-06-28 2006-06-26 Quinolinderivater som antibakterielle midler

Country Status (31)

Country Link
US (1) US8841321B2 (enExample)
EP (1) EP1898914B1 (enExample)
JP (1) JP5193858B2 (enExample)
KR (1) KR101329585B1 (enExample)
CN (1) CN101247811B (enExample)
AP (1) AP2386A (enExample)
AR (1) AR054626A1 (enExample)
AU (1) AU2006263883B2 (enExample)
BR (1) BRPI0612498A8 (enExample)
CA (1) CA2612619C (enExample)
CY (1) CY1113579T1 (enExample)
DK (1) DK1898914T3 (enExample)
EA (1) EA014423B1 (enExample)
ES (1) ES2393203T3 (enExample)
HR (1) HRP20120912T1 (enExample)
IL (1) IL188393A0 (enExample)
JO (1) JO2752B1 (enExample)
ME (1) ME01484B (enExample)
MX (1) MX2008000081A (enExample)
MY (1) MY153291A (enExample)
NO (1) NO342701B1 (enExample)
NZ (1) NZ564379A (enExample)
PA (1) PA8683801A1 (enExample)
PL (1) PL1898914T3 (enExample)
PT (1) PT1898914E (enExample)
RS (1) RS52517B (enExample)
SI (1) SI1898914T1 (enExample)
TW (1) TWI387457B (enExample)
UA (1) UA92175C2 (enExample)
WO (1) WO2007000435A1 (enExample)
ZA (1) ZA200711165B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
ES2576491T3 (es) 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
WO2016105619A1 (en) 2014-12-23 2016-06-30 Albemarle Corporation One-step process for the synthesis of alkylated metyrapone analogs
CN106928139B (zh) * 2017-05-08 2019-06-25 福建省微生物研究所 一种贝达喹啉杂质的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
SI1527050T1 (sl) * 2002-07-25 2010-08-31 Janssen Pharmaceutica Nv Kinolinski derivati in njihova uporaba kot mikobakterijski inhibitorji
WO2005033108A1 (en) * 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
MXPA06013888A (es) * 2004-05-28 2007-01-26 Janssen Pharmaceutica Nv Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos.
EE05394B1 (et) * 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
KR101329587B1 (ko) 2005-06-28 2013-11-15 얀센 파마슈티카 엔.브이. 항균제로서의 퀴놀린 유도체

Also Published As

Publication number Publication date
CN101247811A (zh) 2008-08-20
SI1898914T1 (sl) 2013-01-31
NO20080501L (no) 2008-02-28
HK1122730A1 (en) 2009-05-29
TWI387457B (zh) 2013-03-01
AU2006263883B2 (en) 2012-12-13
NO342701B1 (no) 2018-07-09
JO2752B1 (en) 2014-03-15
WO2007000435A1 (en) 2007-01-04
UA92175C2 (ru) 2010-10-11
CA2612619C (en) 2015-12-01
CN101247811B (zh) 2013-01-02
JP2008543964A (ja) 2008-12-04
PA8683801A1 (es) 2007-01-17
US20100048585A1 (en) 2010-02-25
EA200800154A1 (ru) 2008-10-30
EP1898914A1 (en) 2008-03-19
ME01484B (me) 2014-04-20
NZ564379A (en) 2010-11-26
MX2008000081A (es) 2008-03-24
CA2612619A1 (en) 2007-01-04
BRPI0612498A2 (pt) 2010-11-23
PL1898914T3 (pl) 2013-01-31
EP1898914B1 (en) 2012-08-15
CY1113579T1 (el) 2016-06-22
KR101329585B1 (ko) 2013-11-15
JP5193858B2 (ja) 2013-05-08
KR20080021156A (ko) 2008-03-06
IL188393A0 (en) 2008-08-07
TW200740437A (en) 2007-11-01
ES2393203T3 (es) 2012-12-19
HRP20120912T1 (hr) 2012-12-31
AP2386A (en) 2012-03-23
US8841321B2 (en) 2014-09-23
ZA200711165B (en) 2011-05-25
AR054626A1 (es) 2007-07-04
PT1898914E (pt) 2012-11-20
BRPI0612498A8 (pt) 2018-01-02
MY153291A (en) 2015-01-29
EA014423B1 (ru) 2010-12-30
AU2006263883A1 (en) 2007-01-04
RS52517B (sr) 2013-04-30

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