DK1799290T3 - Nasale indgivelsesindretninger - Google Patents
Nasale indgivelsesindretninger Download PDFInfo
- Publication number
- DK1799290T3 DK1799290T3 DK05789130.1T DK05789130T DK1799290T3 DK 1799290 T3 DK1799290 T3 DK 1799290T3 DK 05789130 T DK05789130 T DK 05789130T DK 1799290 T3 DK1799290 T3 DK 1799290T3
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- DK
- Denmark
- Prior art keywords
- container
- delivery device
- capsule
- chamber
- substance
- Prior art date
Links
- 239000002775 capsule Substances 0.000 claims description 109
- 239000000126 substance Substances 0.000 claims description 72
- 210000003928 nasal cavity Anatomy 0.000 claims description 45
- 239000012530 fluid Substances 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 16
- 210000001331 nose Anatomy 0.000 claims description 9
- 238000011144 upstream manufacturing Methods 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims 8
- 239000003990 capacitor Substances 0.000 claims 1
- 238000007789 sealing Methods 0.000 description 14
- 238000000034 method Methods 0.000 description 5
- 230000004323 axial length Effects 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000011888 foil Substances 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000001828 Gelatine Substances 0.000 description 2
- 239000008186 active pharmaceutical agent Substances 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- 229940088679 drug related substance Drugs 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 230000000116 mitigating effect Effects 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 229940052404 nasal powder Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0098—Activated by exhalation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/1055—Filters bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/1065—Filters in a path in the expiratory path
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- External Artificial Organs (AREA)
- Massaging Devices (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicinal Preparation (AREA)
Claims (30)
1. Nasal indgivelsesindretning til indgivelse af substans til en nasalkavitet hos et individ, hvilken indgivelsesindretning omfatter: en beholder-modtagelsesenhed (16) som omfatter et beholderkammer (23) til at modtage et beholder-indeholdende element (49) som indeholder en substansindeholdende beholder (C) som indeholder substans som skal indgives i nasalkaviteten af individet, hvor beholderkammeret (23) omfatter et indløb (24) og et udløb (25); en næsestykke-enhed (17) som omfatter et næsestykke (47) til tilpasning med en nasalkavitet af individet og som er i fluidforbindelse med udløbet (25) af beholderkammeret (23); og en mundstykke-enhed (19) som omfatter et mundstykke (77) i fluidforbindelse med indløbet (24) af beholderkammeret (23) og igennem hvilket individet under anvendelse udånder, for således at medbringe substans fra beholderen (C) og indgive det samme igennem næsestykket (47), kendetegnet ved at det beholder-indeholdende element (49) omfatter en strømningspassage (63) i hvilken beholderen (C) er anbragt for at kunne rotere deri, når en luftstrøm føres derigennem.
2. Indgivelsesindretning ifølge krav 1, hvor mundstykke-enheden (19) endvidere omfatter et luftkammer (78) som fluidforbinder mundstykket (77) med indløbet (24) af beholderkammeret (23).
3. Indgivelsesindretning ifølge krav 2, hvor luftkammeret (78) omfatter et forlænget rørformet afsnit.
4. Indgivelsesindretning ifølge krav 2 eller 3, hvor luftkammeret (78) har en større volumen end beholderkammeret (23).
5. Indgivelsesindretning ifølge krav 4, hvor luftkammeret (78) har en volumen mindst dobbelt størrelse af den af beholderkammeret (23).
6. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 5, hvor luftkammeret (78) inkorporerer en temperaturregulator (79) til at regulere en temperatur af en luftstrøm idet udåndet derigennem.
7. Indgivelsesindretning ifølge krav 6, hvor temperaturregulatoren (79) er anvendelig til at køle den udåndede luftstrøm.
8. Indgivelsesindretning ifølge krav 6 eller 7, hvor temperaturregulatoren (79) er placeret mindst ved en opstrømsende af luftkammeret (78).
9. Indgivelsesindretning ifølge krav 8, hvor temperaturregulatoren (79) i alt væsentligt udfylder luftkammeret (78).
10. Indgivelsesindretning ifølge et hvilket som helst af kravene 6 til 9, hvor temperaturregulatoren (79) omfatter en labyrintisk kondensator.
11. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 10, endvidere omfattende: en trykfølsom ventil (26) i fluidforbindelse med indløbet (24) af beholderkammeret (23) og som er konfigureret således at den lukker indløbet (24) af beholderkammeret (23) indtil et forudbestemt tryk er udviklet opstrøms af den trykfølsomme ventil (26).
12. Indgivelsesindretning ifølge krav 11, hvor den trykfølsomme ventil (26) omfatter et flapelement (27) som er normalt forspændt til en lukket, forseglet position.
13. Indgivelsesindretning ifølge krav 12, hvor flapelementet (27) kan hængsles rundt om en drejetap (28), og den trykfølsomme ventil (26) omfatter et elastisk element (29) som normalt forspænder flapelementet (27) til den lukkede position.
14. Indgivelsesindretning ifølge et hvilket som helst af kravene 11 til 13, hvor den trykfølsomme ventil (26) er placeret tilstødende indløbet (24) til beholderkammeret (23).
15. Indgivelsesindretning ifølge et hvilket som helst af kravene 11 til 14, hvor beholder-modtagelsesenheden (16) omfatter den trykfølsomme ventil (26).
16. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 15, hvor næsestykke-enheden (17) er aftagelig.
17. Indgivelsesindretning ifølge krav 16, hvor næsestykke-enheden (17) endvidere omfatter et beholder-indeholdende element (49) som indeholder beholderen (C) og er i brug tilpasset i beholderkammeret (23).
18. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 15, endvidere omfattende: et udskifteligt beholder-indeholdende element (49) som indeholder beholderen (C) og er i brug tilpasset i beholderkammeret (23).
19. Indgivelsesindretning ifølge et hvilket som helst af kravene 16 til 18, hvor næsestykke-enheden (17) er udskiftelig.
20. Indgivelsesindretning ifølge et hvilket som helst af kravene 16 til 18, hvor det beholder-indeholdende element (49) er udskifteligt adskilt fra næsestykket (47), som er genanvendeligt.
21. Indgivelsesindretning ifølge et hvilket som helst af kravene 16 til 18, hvor beholderen (C) er udskiftelig og næsestykket (47) og det beholder-indeholdende element (49) som er genanvendelige.
22. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 21, hvor det beholder-indeholdende element (49) inkluderer en indløbsåbning (65) i fluidkommunikation med en opstrømsende afstrømningspassagen (63), hvilken indløbsåbning (65) tilvejebringeren strømbegrænsning til en luftstrøm idet indgivet derigennem.
23. Indgivelsesindretning ifølge krav 22, hvor indløbsåbningen (65) tilvejebringer et sæde til en lavere ende af beholderen (C) forud for indgivelsen af en luftstrøm igennem strømningspassagen (63).
24. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 23, endvidere omfattende: en beholder-åbnende mekanisme (20) som er anvendelig til at åbne en beholder (C) idet modtaget i beholderkammeret (23).
25. Indgivelsesindretning ifølge krav 24, hvor den beholder-åbnende mekanisme (20) inkluderer mindst et gennemtrængende element (83, 85) til at gennemtrænge beholderen (C) for at åbne den samme.
26. Indgivelsesindretning ifølge krav 25, hvor den beholder-åbnende mekanisme (20) inkluderer en flerhed af gennemtrængende elementer (83, 85) til at gennemtrænge beholderen (C) ved en flerhed af positioner anbragt med mellemrum langs længden deraf.
27. Indgivelsesindretning ifølge krav 26, hvor beholderen (C) er kun delvist fyldt og den beholder-åbnende mekanisme (20) inkluderer første og andet gennemtrængende elementer (83, 85), hvor et af de gennemtrængende elementer (83) er konfigureret til at gennemtrænge beholderen (C) ved en højde over et niveau til hvilket beholderen (C) er fyldt og hvor det andet af de gennemtrængende elementer (85) er konfigureret til at gennemtrænge et øvre område af beholderen (C).
28. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 27, hvor beholderen (C) er en kapsel.
29. Indgivelsesindretning ifølge et hvilket som helst af kravene 1 til 28, hvor substansen omfatter en partikelformig substans.
30. Indgivelsesindretning ifølge krav 29, hvor substansen omfatter en pulverformig substans.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0420513A GB0420513D0 (en) | 2004-09-15 | 2004-09-15 | Powder delivery devices |
PCT/GB2005/003549 WO2006030210A2 (en) | 2004-09-15 | 2005-09-15 | Nasal delivery devices |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1799290T3 true DK1799290T3 (da) | 2015-09-14 |
Family
ID=33306617
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05789130.1T DK1799290T3 (da) | 2004-09-15 | 2005-09-15 | Nasale indgivelsesindretninger |
DK12001499.8T DK2462972T3 (da) | 2004-09-15 | 2005-09-15 | Nasal indgivelsesindretning |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12001499.8T DK2462972T3 (da) | 2004-09-15 | 2005-09-15 | Nasal indgivelsesindretning |
Country Status (19)
Country | Link |
---|---|
US (5) | US20080289629A1 (da) |
EP (3) | EP2462972B1 (da) |
JP (5) | JP5032323B2 (da) |
KR (2) | KR101446507B1 (da) |
CN (2) | CN102000374B (da) |
AU (1) | AU2005283922A1 (da) |
BR (1) | BRPI0515289B8 (da) |
CA (3) | CA2839080C (da) |
DK (2) | DK1799290T3 (da) |
ES (2) | ES2546934T3 (da) |
GB (4) | GB0420513D0 (da) |
IL (1) | IL181940A0 (da) |
IN (1) | IN2014DN10605A (da) |
MX (2) | MX2007003052A (da) |
NO (1) | NO337577B1 (da) |
PL (2) | PL2462972T3 (da) |
RU (1) | RU2428217C2 (da) |
SG (1) | SG155889A1 (da) |
WO (1) | WO2006030210A2 (da) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0114272D0 (en) | 2001-06-12 | 2001-08-01 | Optinose As | Nasal delivery device |
ES2439274T3 (es) * | 1999-03-03 | 2014-01-22 | Optinose As | Dispositivo de administración nasal |
GB0121568D0 (en) | 2001-09-06 | 2001-10-24 | Optinose As | Nasal delivery device |
ZA200306564B (en) * | 2001-02-26 | 2004-10-15 | Optinose As | Nasal devices. |
GB0209494D0 (en) * | 2002-04-25 | 2002-06-05 | Optinose As | Nasal devices |
GB0215270D0 (en) | 2002-07-02 | 2002-08-14 | Optinose As | Nasal devices |
GB0215904D0 (en) * | 2002-07-09 | 2002-08-21 | Team Holdings Uk Ltd | Drug delivery system and method |
GB0311570D0 (en) | 2003-05-20 | 2003-06-25 | Optinose As | Delivery device and method |
GB0319119D0 (en) * | 2003-08-14 | 2003-09-17 | Optinose As | Delivery devices |
GB0320171D0 (en) | 2003-08-28 | 2003-10-01 | Optinose As | Delivery devices |
GB0420513D0 (en) | 2004-09-15 | 2004-10-20 | Optinose As | Powder delivery devices |
GB0503738D0 (en) | 2005-02-23 | 2005-03-30 | Optinose As | Powder delivery devices |
US10478574B2 (en) | 2006-01-19 | 2019-11-19 | Optinose As | Nasal administration |
GB0602980D0 (en) * | 2006-02-14 | 2006-03-29 | Optinose As | Delivery device and method |
GB2434990B (en) * | 2006-02-14 | 2010-12-01 | Optinose As | Delivery device and method |
GB0604319D0 (en) * | 2006-03-03 | 2006-04-12 | Optinose As | Nasal delivery |
GB0604444D0 (en) * | 2006-03-06 | 2006-04-12 | Optinose As | Nasal devices |
GB0605799D0 (en) * | 2006-03-23 | 2006-05-03 | Optinose As | Nasal delivery devices |
DE102006016904A1 (de) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
EP1844805A1 (de) * | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH & Co.KG | Inhalator |
GB2437488A (en) * | 2006-04-25 | 2007-10-31 | Optinose As | Pharmaceutical oily formulation for nasal or buccal administration |
GB2438834A (en) * | 2006-06-08 | 2007-12-12 | Optinose As | Intranasal protein administration |
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