DK1778709T3 - Polysulfaterede glykosider og salte deraf - Google Patents

Polysulfaterede glykosider og salte deraf

Info

Publication number
DK1778709T3
DK1778709T3 DK05783149T DK05783149T DK1778709T3 DK 1778709 T3 DK1778709 T3 DK 1778709T3 DK 05783149 T DK05783149 T DK 05783149T DK 05783149 T DK05783149 T DK 05783149T DK 1778709 T3 DK1778709 T3 DK 1778709T3
Authority
DK
Denmark
Prior art keywords
salts
polysulfated glycosides
polysulfated
glycosides
asthma
Prior art date
Application number
DK05783149T
Other languages
Danish (da)
English (en)
Inventor
Istvan Kurucz
Nicholas Bodor
Janos Kuszmann
Gabor Medgyes
Original Assignee
Ivax Drug Res Inst Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Drug Res Inst Ltd filed Critical Ivax Drug Res Inst Ltd
Application granted granted Critical
Publication of DK1778709T3 publication Critical patent/DK1778709T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK05783149T 2004-08-05 2005-08-05 Polysulfaterede glykosider og salte deraf DK1778709T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59914804P 2004-08-05 2004-08-05
PCT/US2005/027877 WO2006017726A2 (en) 2004-08-05 2005-08-05 Polysulfated glycosides and salts thereof

Publications (1)

Publication Number Publication Date
DK1778709T3 true DK1778709T3 (da) 2008-09-22

Family

ID=35781354

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05783149T DK1778709T3 (da) 2004-08-05 2005-08-05 Polysulfaterede glykosider og salte deraf

Country Status (25)

Country Link
US (2) US7902158B2 (pt)
EP (1) EP1778709B1 (pt)
JP (1) JP5164572B2 (pt)
KR (1) KR101097702B1 (pt)
CN (1) CN101014607B (pt)
AT (1) ATE397006T1 (pt)
AU (1) AU2005271349B2 (pt)
BR (1) BRPI0513095A (pt)
CA (1) CA2576131C (pt)
CY (1) CY1108900T1 (pt)
DE (1) DE602005007244D1 (pt)
DK (1) DK1778709T3 (pt)
ES (1) ES2308536T3 (pt)
HK (1) HK1098758A1 (pt)
IL (1) IL181095A (pt)
MX (1) MX2007001444A (pt)
NO (1) NO20070987L (pt)
NZ (1) NZ553292A (pt)
PL (1) PL1778709T3 (pt)
PT (1) PT1778709E (pt)
RU (1) RU2413734C2 (pt)
SI (1) SI1778709T1 (pt)
UA (1) UA87154C2 (pt)
WO (1) WO2006017726A2 (pt)
ZA (1) ZA200700758B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1778709T1 (sl) 2004-08-05 2008-12-31 Ivax Drug Res Inst Ltd Polisulfatirani glikozidi in njihove soli
WO2010037180A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic oligosaccharide conjugates
RU2519781C2 (ru) * 2009-02-02 2014-06-20 Оцука Кемикал Ко., Лтд. Низкомолекулярное полисульфатированное производное гиалуроновой кислоты и содержащее его лекарственное средство
PL399450A1 (pl) * 2009-08-31 2013-01-21 Depomed, Inc Utrzymujace sie w zoladku kompozycje farmaceutyczne do natychmiastowego i przedluzonego uwalniania acetaminofenu
MX2012006265A (es) 2009-12-03 2012-07-25 Opko Health Inc Formulaciones disacaridas hipersulfatadas.
US20130203695A1 (en) * 2010-10-29 2013-08-08 Opko Health, Inc. Hypersulfated disaccharides to treat elastase related disorders
WO2012058719A1 (en) * 2010-11-02 2012-05-10 The Universtity Of Sydney Inhalable compositions
PT3274347T (pt) * 2015-03-26 2020-10-01 Giuliani Spa Compostos tendo atividade antioxidante contra radicais livres e atividade anti-inflamatória, e correspondentes composições farmacêuticas para o cuidado da pele
WO2018035050A1 (en) 2016-08-16 2018-02-22 Opko Pharmaceuticals, Llc Pure heptasulfated disaccharides having improved oral bioavailability
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
WO2018043666A1 (ja) 2016-08-31 2018-03-08 王子ホールディングス株式会社 酸性キシロオリゴ糖の製造方法
JP6281659B1 (ja) * 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
SG11201911318SA (en) 2017-05-31 2020-01-30 Oji Holdings Corp Moisturizing topical preparation
BR112020004787A2 (pt) 2017-09-12 2020-09-24 Oji Holdings Corporation polissulfato de pentosano, composição farmacêutica, anticoagulante, e, método para produzir polissulfato de pentosano
PL3730521T3 (pl) 2017-12-20 2023-10-09 Oji Holdings Corporation Polisiarczan pentozanu i lek zawierający polisiarczan pentozanu

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5380716A (en) * 1988-12-15 1995-01-10 Glycomed, Inc. Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
JPH05164572A (ja) 1991-12-12 1993-06-29 Y E Data Inc エンコーダ
DE69316754T2 (de) * 1992-06-01 1998-07-16 Biomembrane Inst Schrittweise entfernung von monosacchariden vom reduzierenden ende von oligosacchariden und verwendungen davon
DE4408248A1 (de) * 1994-03-11 1995-09-14 Hoechst Ag Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
JPH08109134A (ja) * 1994-10-11 1996-04-30 Sanwa Kagaku Kenkyusho Co Ltd 細胞変成抑制並びに臓器毒性軽減剤
US6153736A (en) * 1995-09-27 2000-11-28 The Liposome Company, Inc. Modified ether glyceroglycolipids
JPH09183789A (ja) 1995-10-31 1997-07-15 Sanwa Kagaku Kenkyusho Co Ltd 新規な硫酸化及び燐酸化糖誘導体、その製法及び用途
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
JP4913272B2 (ja) 1999-01-07 2012-04-11 生化学工業株式会社 オリゴ糖の製造方法ならびに新規オリゴ糖およびそれを含む医薬組成物
WO2002083700A2 (en) * 2001-04-16 2002-10-24 Ivax Research, Inc. Hypersulfated disaccharides and methods of using the same for the treatment of inflammations
BR0311645A (pt) * 2002-06-07 2005-02-22 Dzucker Ag Mannheim Ochsenfurt Isomalte de galactosila - procedimento para sua produção e emprego
SI1778709T1 (sl) 2004-08-05 2008-12-31 Ivax Drug Res Inst Ltd Polisulfatirani glikozidi in njihove soli
SE535900C2 (sv) 2008-10-16 2013-02-12 Rolls Royce Ab Anordning för propellerpitchstyrning

Also Published As

Publication number Publication date
WO2006017726A2 (en) 2006-02-16
ATE397006T1 (de) 2008-06-15
NO20070987L (no) 2007-04-11
AU2005271349A1 (en) 2006-02-16
IL181095A (en) 2013-07-31
IL181095A0 (en) 2007-07-04
ZA200700758B (en) 2008-08-27
KR101097702B1 (ko) 2011-12-22
US20110118198A1 (en) 2011-05-19
BRPI0513095A (pt) 2008-03-11
AU2005271349B2 (en) 2011-10-27
DE602005007244D1 (de) 2008-07-10
MX2007001444A (es) 2007-07-04
RU2007107935A (ru) 2008-09-10
SI1778709T1 (sl) 2008-12-31
US20070281893A1 (en) 2007-12-06
RU2413734C2 (ru) 2011-03-10
NZ553292A (en) 2009-06-26
EP1778709A2 (en) 2007-05-02
CA2576131C (en) 2012-04-24
HK1098758A1 (en) 2007-07-27
CN101014607A (zh) 2007-08-08
UA87154C2 (uk) 2009-06-25
CA2576131A1 (en) 2006-02-16
KR20070042188A (ko) 2007-04-20
WO2006017726A3 (en) 2006-04-20
US7902158B2 (en) 2011-03-08
JP2008509156A (ja) 2008-03-27
CY1108900T1 (el) 2014-07-02
CN101014607B (zh) 2014-05-14
PT1778709E (pt) 2008-07-24
EP1778709B1 (en) 2008-05-28
JP5164572B2 (ja) 2013-03-21
PL1778709T3 (pl) 2008-10-31
ES2308536T3 (es) 2008-12-01
US8987216B2 (en) 2015-03-24

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