CY1108900T1 - Πολυθειωμενα γλυκοζιδια και αλατα αυτων - Google Patents

Πολυθειωμενα γλυκοζιδια και αλατα αυτων

Info

Publication number
CY1108900T1
CY1108900T1 CY20081100899T CY081100899T CY1108900T1 CY 1108900 T1 CY1108900 T1 CY 1108900T1 CY 20081100899 T CY20081100899 T CY 20081100899T CY 081100899 T CY081100899 T CY 081100899T CY 1108900 T1 CY1108900 T1 CY 1108900T1
Authority
CY
Cyprus
Prior art keywords
salts
polyphylened
glucose
asthma
airways
Prior art date
Application number
CY20081100899T
Other languages
English (en)
Inventor
Janos Kuszmann
Istvan Kurucz
Gabor Medgyes
Nicholas Bodor
Original Assignee
Ivax Drug Research Institute Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Drug Research Institute Ltd filed Critical Ivax Drug Research Institute Ltd
Publication of CY1108900T1 publication Critical patent/CY1108900T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Η εφεύρεση αφορά πολυθειωμένα γλυκοζίδια του τύπου (I), τα φαρμακευτικώς αποδεκτά άλατα αυτών, καθώς επίσης τις φαρμακευτικές συνθέσεις που περιέχουν αυτές τις ενώσεις ως δραστικά συστατικά. Περαιτέρω η εφεύρεση παρέχει μέθοδο αποτροπής, θεραπείας ή ανακούφισης των συμπτωμάτων οξειών και χρόνιων φλεγμονωδών διαταραχών των αεροδών θηλαστικών, συμπεριλαμβανομένου άσθματος και σχετικών με άσθμα παθολογιών.
CY20081100899T 2004-08-05 2008-08-25 Πολυθειωμενα γλυκοζιδια και αλατα αυτων CY1108900T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59914804P 2004-08-05 2004-08-05
EP05783149A EP1778709B1 (en) 2004-08-05 2005-08-05 Polysulfated glycosides and salts thereof

Publications (1)

Publication Number Publication Date
CY1108900T1 true CY1108900T1 (el) 2014-07-02

Family

ID=35781354

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100899T CY1108900T1 (el) 2004-08-05 2008-08-25 Πολυθειωμενα γλυκοζιδια και αλατα αυτων

Country Status (25)

Country Link
US (2) US7902158B2 (el)
EP (1) EP1778709B1 (el)
JP (1) JP5164572B2 (el)
KR (1) KR101097702B1 (el)
CN (1) CN101014607B (el)
AT (1) ATE397006T1 (el)
AU (1) AU2005271349B2 (el)
BR (1) BRPI0513095A (el)
CA (1) CA2576131C (el)
CY (1) CY1108900T1 (el)
DE (1) DE602005007244D1 (el)
DK (1) DK1778709T3 (el)
ES (1) ES2308536T3 (el)
HK (1) HK1098758A1 (el)
IL (1) IL181095A (el)
MX (1) MX2007001444A (el)
NO (1) NO20070987L (el)
NZ (1) NZ553292A (el)
PL (1) PL1778709T3 (el)
PT (1) PT1778709E (el)
RU (1) RU2413734C2 (el)
SI (1) SI1778709T1 (el)
UA (1) UA87154C2 (el)
WO (1) WO2006017726A2 (el)
ZA (1) ZA200700758B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE397006T1 (de) 2004-08-05 2008-06-15 Ivax Drug Res Inst Ltd Polysulfatierte glykoside und salze davon
WO2010037180A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic oligosaccharide conjugates
SG2014006985A (en) * 2009-02-02 2014-04-28 Otsuka Pharma Co Ltd Low-molecular polysulfated hyaluronic acid derivative and medicine containing same
KR20120059582A (ko) * 2009-08-31 2012-06-08 데포메드 인코퍼레이티드 아세트아미노펜의 속방성 및 서방성을 위한 위 체류 약제학적 조성물
MX2012006265A (es) 2009-12-03 2012-07-25 Opko Health Inc Formulaciones disacaridas hipersulfatadas.
RU2013116520A (ru) * 2010-10-29 2014-12-10 Опко Хелс, Инк. Гиперсульфатированные дисахариды для лечения нарушений, связанных с эластазой
WO2012058719A1 (en) * 2010-11-02 2012-05-10 The Universtity Of Sydney Inhalable compositions
RS60870B1 (sr) * 2015-03-26 2020-11-30 Giuliani Spa Jedinjenja sa antioksidativnim dejstvom na slobodne radikale i antizapaljenskim dejstvom, i odgovarajuće farmaceutske kompozicije za negu kože
TW201815394A (zh) 2016-08-16 2018-05-01 美商歐科製藥有限公司 具有改良口服生物可利用性之純七硫酸化雙醣
MX2020002288A (es) 2016-08-31 2020-07-14 Oji Holdings Corp Metodo de produccion para xilooligosacarido acido y xilooligosacarido acido.
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
KR20240023711A (ko) 2017-05-31 2024-02-22 오지 홀딩스 가부시키가이샤 보습 외용제
MX2020002726A (es) 2017-09-12 2020-07-20 Oji Holdings Corp Polisulfato de pentosan y metodo para producir polisulfato de pentosan.
HUE062342T2 (hu) 2017-12-20 2023-10-28 Oji Holdings Corp Pentozán-poliszulfát, valamint pentozán-poliszulfátot tartalmazó gyógyszerek

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US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5380716A (en) 1988-12-15 1995-01-10 Glycomed, Inc. Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
JPH05164572A (ja) 1991-12-12 1993-06-29 Y E Data Inc エンコーダ
ATE162794T1 (de) 1992-06-01 1998-02-15 Biomembrane Inst Schrittweise entfernung von monosacchariden vom reduzierenden ende von oligosacchariden und verwendungen davon
DE4408248A1 (de) * 1994-03-11 1995-09-14 Hoechst Ag Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
JPH08109134A (ja) * 1994-10-11 1996-04-30 Sanwa Kagaku Kenkyusho Co Ltd 細胞変成抑制並びに臓器毒性軽減剤
US6153736A (en) * 1995-09-27 2000-11-28 The Liposome Company, Inc. Modified ether glyceroglycolipids
JPH09183789A (ja) 1995-10-31 1997-07-15 Sanwa Kagaku Kenkyusho Co Ltd 新規な硫酸化及び燐酸化糖誘導体、その製法及び用途
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
JP4913272B2 (ja) 1999-01-07 2012-04-11 生化学工業株式会社 オリゴ糖の製造方法ならびに新規オリゴ糖およびそれを含む医薬組成物
AR035827A1 (es) * 2001-04-16 2004-07-14 Ivax Research Inc Disacaridos hipersulfatados
ATE339512T1 (de) * 2002-06-07 2006-10-15 Suedzucker Ag Galactosyl-isomalt, verfahren zu seiner herstellung und verwendung
ATE397006T1 (de) 2004-08-05 2008-06-15 Ivax Drug Res Inst Ltd Polysulfatierte glykoside und salze davon
SE535900C2 (sv) 2008-10-16 2013-02-12 Rolls Royce Ab Anordning för propellerpitchstyrning

Also Published As

Publication number Publication date
RU2007107935A (ru) 2008-09-10
NO20070987L (no) 2007-04-11
CA2576131A1 (en) 2006-02-16
AU2005271349B2 (en) 2011-10-27
ZA200700758B (en) 2008-08-27
ES2308536T3 (es) 2008-12-01
CN101014607B (zh) 2014-05-14
PL1778709T3 (pl) 2008-10-31
CN101014607A (zh) 2007-08-08
JP2008509156A (ja) 2008-03-27
MX2007001444A (es) 2007-07-04
US7902158B2 (en) 2011-03-08
ATE397006T1 (de) 2008-06-15
IL181095A (en) 2013-07-31
AU2005271349A1 (en) 2006-02-16
JP5164572B2 (ja) 2013-03-21
KR20070042188A (ko) 2007-04-20
WO2006017726A3 (en) 2006-04-20
BRPI0513095A (pt) 2008-03-11
CA2576131C (en) 2012-04-24
UA87154C2 (uk) 2009-06-25
US20070281893A1 (en) 2007-12-06
WO2006017726A2 (en) 2006-02-16
DE602005007244D1 (de) 2008-07-10
HK1098758A1 (en) 2007-07-27
EP1778709B1 (en) 2008-05-28
IL181095A0 (en) 2007-07-04
PT1778709E (pt) 2008-07-24
RU2413734C2 (ru) 2011-03-10
DK1778709T3 (da) 2008-09-22
US20110118198A1 (en) 2011-05-19
US8987216B2 (en) 2015-03-24
NZ553292A (en) 2009-06-26
KR101097702B1 (ko) 2011-12-22
SI1778709T1 (sl) 2008-12-31
EP1778709A2 (en) 2007-05-02

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