US6204261B1
(en)
*
|
1995-12-20 |
2001-03-20 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β Converting enzyme inhibitors
|
US6008217A
(en)
*
|
1995-12-20 |
1999-12-28 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5874424A
(en)
*
|
1995-12-20 |
1999-02-23 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
SE8804164A0
(sv)
*
|
1988-11-17 |
1990-05-18 |
Per Prisell |
Farmaceutisk beredning
|
ATE178094T1
(de)
*
|
1990-05-01 |
1999-04-15 |
Chiron Corp |
Interleukin-i antagonist und seine verwendung
|
US5872095A
(en)
*
|
1990-05-01 |
1999-02-16 |
Chiron Corporation |
IL-1 receptor antagonists medicaments
|
WO1991018982A1
(fr)
*
|
1990-06-05 |
1991-12-12 |
Immunex Corporation |
Recepteurs de l'interleukine-1 de type ii
|
US5824549A
(en)
*
|
1990-10-09 |
1998-10-20 |
Chiron Corporation |
Transformed human T cell
|
US5932537A
(en)
*
|
1990-10-09 |
1999-08-03 |
Chiron Corporation |
Method for attenuating a cellular response to IL-1
|
US5858355A
(en)
*
|
1990-12-20 |
1999-01-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
IRAP gene as treatment for arthritis
|
US6413511B1
(en)
|
1990-12-20 |
2002-07-02 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
|
WO1992011359A1
(fr)
*
|
1990-12-20 |
1992-07-09 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Gene recepteur tronque d'interleukine-1 utilise pour le traitement de l'arthrite
|
US6159464A
(en)
*
|
1990-12-20 |
2000-12-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
|
US6156304A
(en)
*
|
1990-12-20 |
2000-12-05 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Gene transfer for studying and treating a connective tissue of a mammalian host
|
US6228356B1
(en)
*
|
1990-12-20 |
2001-05-08 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
|
US6673335B1
(en)
*
|
1992-07-08 |
2004-01-06 |
Nektar Therapeutics |
Compositions and methods for the pulmonary delivery of aerosolized medicaments
|
US6582728B1
(en)
*
|
1992-07-08 |
2003-06-24 |
Inhale Therapeutic Systems, Inc. |
Spray drying of macromolecules to produce inhaleable dry powders
|
US6509006B1
(en)
|
1992-07-08 |
2003-01-21 |
Inhale Therapeutic Systems, Inc. |
Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
|
US7448375B2
(en)
*
|
1993-01-29 |
2008-11-11 |
Aradigm Corporation |
Method of treating diabetes mellitus in a patient
|
US6024090A
(en)
*
|
1993-01-29 |
2000-02-15 |
Aradigm Corporation |
Method of treating a diabetic patient by aerosolized administration of insulin lispro
|
NZ263102A
(en)
*
|
1993-03-19 |
1997-05-26 |
Immunex Corp |
Pharmaceutical compositions comprising a ligand protein such as interleukin-4 and a soluble receptor protein that binds thereto
|
US5536657A
(en)
*
|
1993-07-19 |
1996-07-16 |
Hoffmann-La Roche Inc. |
Recombinant DNA encoding human receptor for interleukin-12
|
AU1513495A
(en)
*
|
1993-12-14 |
1995-07-03 |
University Of Pittsburgh |
Systemic gene treatment of connective tissue diseases
|
US20040161416A1
(en)
*
|
1993-12-14 |
2004-08-19 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Systemic gene treatment of connective tissue diseases
|
US6051256A
(en)
|
1994-03-07 |
2000-04-18 |
Inhale Therapeutic Systems |
Dispersible macromolecule compositions and methods for their preparation and use
|
MX9603936A
(es)
*
|
1994-03-07 |
1997-05-31 |
Inhale Therapeutic Syst |
Metodos y composiciones para el suministro pulmonar de insulina.
|
JPH083058A
(ja)
*
|
1994-06-17 |
1996-01-09 |
Hoechst Japan Ltd |
新規な骨代謝疾患治療剤
|
US5847135A
(en)
*
|
1994-06-17 |
1998-12-08 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5716929A
(en)
*
|
1994-06-17 |
1998-02-10 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1β converting enzyme
|
US6420522B1
(en)
*
|
1995-06-05 |
2002-07-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5756466A
(en)
*
|
1994-06-17 |
1998-05-26 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1β converting enzyme
|
US6239268B1
(en)
|
1994-09-09 |
2001-05-29 |
Neurocrine Biosciences, Inc. |
Interleukin-1 type 3 receptors
|
US20040127884A1
(en)
*
|
1994-12-12 |
2004-07-01 |
Omeros Corporation |
Vascular irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis
|
US7091181B2
(en)
|
1994-12-12 |
2006-08-15 |
Omeros Corporation |
Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
|
US20020028798A1
(en)
*
|
1995-12-12 |
2002-03-07 |
Omeros Medical Systems |
Irrigation solution and method for inhibition of pain and inflammation
|
AU4467396A
(en)
|
1994-12-12 |
1996-07-10 |
Omeros Medical Systems, Inc. |
Irrigation solution and method for inhibition of pain, inflammation and spasm
|
US5780014A
(en)
*
|
1995-04-14 |
1998-07-14 |
Inhale Therapeutic Systems |
Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
|
US5843904A
(en)
*
|
1995-12-20 |
1998-12-01 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1βconverting enzyme
|
US6491922B1
(en)
|
1996-02-09 |
2002-12-10 |
Cornell Research Foundation, Inc. |
Methods and compounds for treating autoimmune and vascular disease
|
US5776731A
(en)
*
|
1996-02-21 |
1998-07-07 |
Immunex Corporation |
DNA encoding type-I interleukin-I receptor-like protein designated 2F1
|
CA2200119C
(fr)
*
|
1996-03-18 |
2005-08-16 |
Masaru Nakatani |
Adsorbant pour eliminer les chimiokines, methode pour ce faire et adsorbeur utilise a cette fin
|
US5753218A
(en)
*
|
1996-05-03 |
1998-05-19 |
Schering Corporation |
Method for treating inflammation
|
AU5154098A
(en)
*
|
1996-10-31 |
1998-05-22 |
Duke University |
Soluble tie2 receptor
|
EP0959897B1
(fr)
|
1996-11-27 |
2009-04-22 |
Immunex Corporation |
Procede permettant de reguler la production de monoxyde d'azote
|
ES2615357T3
(es)
|
1996-12-06 |
2017-06-06 |
Amgen Inc. |
Terapia de combinación usando un inhibidor de IL-1 para tratar enfermedades mediadas por IL-1
|
US20030203036A1
(en)
*
|
2000-03-17 |
2003-10-30 |
Gordon Marc S. |
Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
|
US6063600A
(en)
*
|
1997-05-23 |
2000-05-16 |
Uab Research Foundation |
DNA encoding canine interleukin-1 receptor antagonist
|
US6054754A
(en)
|
1997-06-06 |
2000-04-25 |
Micron Technology, Inc. |
Multi-capacitance lead frame decoupling device
|
US5965704A
(en)
*
|
1997-08-05 |
1999-10-12 |
Zymogenetics, Inc. |
Class two cytokine receptor-11
|
AU737592B2
(en)
|
1998-01-23 |
2001-08-23 |
Immunex Corporation |
Il-18 receptors
|
US7029861B1
(en)
|
1998-09-15 |
2006-04-18 |
Board Of Regents, The University Of Texas System |
LPS-response gene compositions and methods
|
US7067144B2
(en)
*
|
1998-10-20 |
2006-06-27 |
Omeros Corporation |
Compositions and methods for systemic inhibition of cartilage degradation
|
MXPA01006006A
(es)
|
1998-12-14 |
2004-08-12 |
Genetics Inst |
Cadena receptora de citocina.
|
US7553487B2
(en)
|
1998-12-14 |
2009-06-30 |
Genetics Institute, Llc |
Method and compositions for treating asthma
|
US20020077276A1
(en)
*
|
1999-04-27 |
2002-06-20 |
Fredeking Terry M. |
Compositions and methods for treating hemorrhagic virus infections and other disorders
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
AU2253301A
(en)
*
|
1999-12-03 |
2001-06-12 |
Zymogenetics Inc. |
Human cytokine receptor
|
US20030170823A1
(en)
*
|
1999-12-23 |
2003-09-11 |
Presnell Scott R. |
Novel cytokine ZCYTO18
|
AR030554A1
(es)
|
2000-03-16 |
2003-08-27 |
Amgen Inc |
Moleculas similares a receptores il-17 y usos de las mismas
|
EP2329842A3
(fr)
*
|
2000-05-12 |
2011-07-27 |
Immunex Corporation |
Inhibiteurs d'interleukine 1 dans le traitement de maladies
|
US7575761B2
(en)
*
|
2000-06-30 |
2009-08-18 |
Novartis Pharma Ag |
Spray drying process control of drying kinetics
|
AU2001290524A1
(en)
*
|
2000-08-08 |
2002-02-18 |
Zymogenetics Inc. |
Soluble zcytor 11 cytokine receptors
|
EP1736545A3
(fr)
*
|
2000-08-08 |
2007-03-28 |
ZymoGenetics, Inc. |
Récepteurs de cytokines zcytor 11 solubles
|
US20030026806A1
(en)
*
|
2000-10-27 |
2003-02-06 |
Amgen Inc. |
Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
|
CA2439961A1
(fr)
*
|
2001-03-27 |
2002-10-03 |
Zymogenetics, Inc. |
Recepteur de cytokine humaine
|
PL222211B1
(pl)
|
2001-06-26 |
2016-07-29 |
Amgen Fremont Inc |
Przeciwciało przeciwko OPGL, kompozycja je zawierająca, jego zastosowanie i sposób jego wytwarzania, sposób wykrywania poziomu OPGL, kompozycja obejmująca polinukleotydy i komórka gosodarza
|
WO2003002187A2
(fr)
*
|
2001-06-26 |
2003-01-09 |
Photomed Technologies, Inc. |
Illuminateur a longueurs d'onde multiples
|
AU2002324625B2
(en)
*
|
2001-08-07 |
2008-05-08 |
Immunex Corporation |
Interleukin-1 receptors in the treatment of diseases
|
CA2464529A1
(fr)
*
|
2001-11-06 |
2003-05-15 |
Applied Research Systems Ars Holding N.V. |
Methode de traitement du cancer du sein repondant aux oestrogenes
|
AU2003223344B9
(en)
*
|
2002-03-22 |
2009-07-16 |
Zymogenetics, Inc. |
Anti-IL-TIF antibodies and methods of using in inflammation
|
GB0216562D0
(en)
*
|
2002-04-25 |
2002-08-28 |
Bradford Particle Design Ltd |
Particulate materials
|
US9339459B2
(en)
|
2003-04-24 |
2016-05-17 |
Nektar Therapeutics |
Particulate materials
|
NZ593428A
(en)
|
2002-09-06 |
2013-01-25 |
Amgen Inc |
Therapeutic human anti-il-1r1 monoclonal antibody
|
WO2004060911A2
(fr)
*
|
2002-12-30 |
2004-07-22 |
Amgen Inc. |
Polytherapie a facteurs costimulants
|
EP1606316A2
(fr)
*
|
2003-03-24 |
2005-12-21 |
ZymoGenetics, Inc. |
Anticorps anti-il-20 et leurs partenaires de liaison, methodes d'utilisation de ces derniers dans les cas d'inflammation
|
US6768069B1
(en)
*
|
2003-04-08 |
2004-07-27 |
Shin Jiuh Corp. |
Micro switch
|
WO2004098597A1
(fr)
*
|
2003-05-12 |
2004-11-18 |
Altana Pharma Ag |
Composition contenant du roflumilast et du shuil-1r ii
|
JP4943161B2
(ja)
|
2003-12-23 |
2012-05-30 |
ジェネンテック, インコーポレイテッド |
新規抗il13モノクローナル抗体での癌の処置
|
AU2005231822B2
(en)
*
|
2004-04-02 |
2011-07-21 |
Swedish Orphan Biovitrum Ab (Publ) |
Methods of reducing aggregation of IL-1ra
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
US7501121B2
(en)
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
WO2006047249A1
(fr)
|
2004-10-22 |
2006-05-04 |
Zymogenetics, Inc. |
Anticorps anti-il-22ra et partenaires de liaison et methodes d'utilisation de ces anticorps et de ces partenaires de liaison pour le traitement de maladies inflammatoires
|
US20060147945A1
(en)
*
|
2005-01-06 |
2006-07-06 |
Edmonds Brian T |
Novel secreted proteins and their uses
|
CA2596390A1
(fr)
*
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anticorps et partenaires de liaison anti-il-20, anti-il-22 et anti-il-22ra, et methodes d'utilisation de ces anticorps et partenaires de liaison dans des processus inflammatoires
|
JP2008543449A
(ja)
*
|
2005-06-17 |
2008-12-04 |
アボット・ラボラトリーズ |
変性脊椎疾患の改良型治療方法
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
US11939634B2
(en)
|
2010-05-18 |
2024-03-26 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
NZ756749A
(en)
|
2013-09-13 |
2022-05-27 |
Genentech Inc |
Methods and compositions comprising purified recombinant polypeptides
|
RU2016107435A
(ru)
|
2013-09-13 |
2017-10-18 |
Дженентек, Инк. |
Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
|
US11479812B2
(en)
|
2015-05-11 |
2022-10-25 |
Natera, Inc. |
Methods and compositions for determining ploidy
|
US10041044B2
(en)
|
2016-07-29 |
2018-08-07 |
Trustees Of Boston University |
Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
|
CA3067637A1
(fr)
|
2017-06-20 |
2018-12-27 |
The Medical College Of Wisconsin, Inc. |
Evaluation du risque de complication d'une greffe avec l'adn acellulaire total
|
WO2020035482A1
(fr)
|
2018-08-13 |
2020-02-20 |
Iltoo Pharma |
Combinaison d'interleukine 2 et d'un inhibiteur de l'interleukine 1, conjugués et utilisations thérapeutiques de celle-ci
|
US11931674B2
(en)
|
2019-04-04 |
2024-03-19 |
Natera, Inc. |
Materials and methods for processing blood samples
|
WO2021236962A1
(fr)
|
2020-05-20 |
2021-11-25 |
The Medical College Of Wisconsin, Inc. |
Compositions et méthodes d'inhibition du syndrôme de libération des cytokines
|
CN111793646B
(zh)
*
|
2020-09-08 |
2021-01-15 |
北京百奥赛图基因生物技术有限公司 |
Il1r1基因人源化改造的非人动物的构建方法及其应用
|