CA2299619A1 - Nouveau recepteur orphelin - Google Patents

Nouveau recepteur orphelin Download PDF

Info

Publication number
CA2299619A1
CA2299619A1 CA002299619A CA2299619A CA2299619A1 CA 2299619 A1 CA2299619 A1 CA 2299619A1 CA 002299619 A CA002299619 A CA 002299619A CA 2299619 A CA2299619 A CA 2299619A CA 2299619 A1 CA2299619 A1 CA 2299619A1
Authority
CA
Canada
Prior art keywords
ntr
human
human ntr
polypeptide
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002299619A
Other languages
English (en)
Inventor
Piotr J. Masiakowski
Jodi Morris
David M. Valenzuela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2299619A1 publication Critical patent/CA2299619A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention porte sur une séquence d'acide nucléique dite HUMAN NTR-1 codant pour un nouveau récepteur orphelin exprimé dans le pancréas et le coeur du foetus. L'invention porte également sur des systèmes d'essai pouvant servir à détecter ou mesurer les ligands se fixant au produit génique HUMAN NTR-1; elle porte en outre sur des procédés thérapeutiques basés sur l'interaction entre le NTR-1 et des agents provoquant la transduction de signaux en se fixant au NTR-1.
CA002299619A 1997-08-06 1998-08-04 Nouveau recepteur orphelin Abandoned CA2299619A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5486997P 1997-08-06 1997-08-06
US60/054,869 1997-08-06
PCT/US1998/016202 WO1999007738A2 (fr) 1997-08-06 1998-08-04 Nouveau recepteur orphelin

Publications (1)

Publication Number Publication Date
CA2299619A1 true CA2299619A1 (fr) 1999-02-18

Family

ID=21994032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002299619A Abandoned CA2299619A1 (fr) 1997-08-06 1998-08-04 Nouveau recepteur orphelin

Country Status (5)

Country Link
EP (1) EP1019502A2 (fr)
JP (1) JP2001512667A (fr)
AU (1) AU8767698A (fr)
CA (1) CA2299619A1 (fr)
WO (1) WO1999007738A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1247567A (zh) 1997-01-14 2000-03-15 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
DK1015587T3 (da) 1997-09-18 2008-08-25 Genentech Inc DcR3 polypeptid, en TNFR-homolog
WO1999026977A1 (fr) * 1997-11-24 1999-06-03 Biogen, Inc. Recepteurs 'opg-2'
WO1999031128A2 (fr) * 1997-12-16 1999-06-24 Incyte Pharmaceuticals, Inc. Proteines du type facteur humain de necrose tumorale r2
DE19809978A1 (de) * 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
HUP0102067A2 (hu) * 1998-03-30 2001-10-28 Eli Lilly And Co. A TNF receptorcsaládba tartozó érett FLINT (mFLINT) polipeptid vagy más néven az OPG3 terápiás alkalmazásai
AU2211100A (en) * 1998-12-22 2000-07-12 Eli Lilly And Company Therapeutic applications of flint polypeptides
CA2359757A1 (fr) 1999-02-10 2000-08-17 Genset S.A. Marqueurs polymorphes du gene lsr
NZ513294A (en) * 1999-03-04 2004-04-30 Human Genome Sciences Inc Tumor necrosis factor receptors 6alpha and 6beta
US6329159B1 (en) * 1999-03-11 2001-12-11 Millennium Pharmaceuticals, Inc. Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function
US6965012B1 (en) * 1999-03-30 2005-11-15 Eli Lilly And Company Flint polypeptide analogs
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
US6521422B1 (en) 1999-08-04 2003-02-18 Amgen Inc. Fhm, a novel member of the TNF ligand supergene family
AU6517800A (en) 1999-08-04 2001-03-05 Amgen, Inc. Ntr3, a member of the tnf-receptor supergene family
US7338787B2 (en) 2000-01-14 2008-03-04 Serono Genetics Institute S.A. Nucleic acids encoding OBG3 globular head and uses thereof
DE60028830T2 (de) 2000-02-16 2007-01-18 Genentech, Inc., South San Francisco Anti-april antikörper und hybridomazellen
EP1272647B1 (fr) 2000-04-11 2014-11-12 Genentech, Inc. Anticorps multivalents et leurs utilisations
IL153948A0 (en) 2000-07-27 2003-07-31 Genentech Inc Apo-2l receptor agonist and cpt-11 synergism
CA2451680C (fr) 2001-07-03 2011-04-19 Genentech, Inc. Anticorps humains du dr4 et utilisations
CA2629306A1 (fr) 2005-11-23 2007-05-31 Genentech, Inc. Procedes et compositions lies a des analyses de lymphocytes b

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
US6369027B1 (en) * 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin
CN1247567A (zh) * 1997-01-14 2000-03-15 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
US5885800A (en) * 1997-02-04 1999-03-23 Smithkline Beecham Corporation DNA encoding tumor necrosis related receptor, TR4

Also Published As

Publication number Publication date
WO1999007738A2 (fr) 1999-02-18
AU8767698A (en) 1999-03-01
WO1999007738A3 (fr) 1999-04-15
EP1019502A2 (fr) 2000-07-19
JP2001512667A (ja) 2001-08-28

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20040804