DK175256B1 - Substituerede 1,2,4-triazindioner, fremgangsmåder og mellemprodukter til deres fremstilling samt deres anvendelse - Google Patents
Substituerede 1,2,4-triazindioner, fremgangsmåder og mellemprodukter til deres fremstilling samt deres anvendelse Download PDFInfo
- Publication number
- DK175256B1 DK175256B1 DK198900837A DK83789A DK175256B1 DK 175256 B1 DK175256 B1 DK 175256B1 DK 198900837 A DK198900837 A DK 198900837A DK 83789 A DK83789 A DK 83789A DK 175256 B1 DK175256 B1 DK 175256B1
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compounds
- alkyl
- hydrogen
- triazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
- C07C255/65—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
- C07C271/64—Y being a hydrogen or a carbon atom, e.g. benzoylcarbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/48—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3805660 | 1988-02-24 | ||
| DE3805660A DE3805660A1 (de) | 1988-02-24 | 1988-02-24 | Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK83789D0 DK83789D0 (da) | 1989-02-23 |
| DK83789A DK83789A (da) | 1989-08-25 |
| DK175256B1 true DK175256B1 (da) | 2004-07-26 |
Family
ID=6347991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198900837A DK175256B1 (da) | 1988-02-24 | 1989-02-23 | Substituerede 1,2,4-triazindioner, fremgangsmåder og mellemprodukter til deres fremstilling samt deres anvendelse |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4935423A (sk) |
| EP (1) | EP0330041B1 (sk) |
| JP (1) | JP2703607B2 (sk) |
| KR (1) | KR0133292B1 (sk) |
| AT (1) | ATE104296T1 (sk) |
| AU (1) | AU606266B2 (sk) |
| BR (1) | BR8900834A (sk) |
| CA (1) | CA1328868C (sk) |
| CZ (1) | CZ282916B6 (sk) |
| DD (1) | DD284012A5 (sk) |
| DE (2) | DE3805660A1 (sk) |
| DK (1) | DK175256B1 (sk) |
| ES (1) | ES2063063T3 (sk) |
| HU (1) | HU215836B (sk) |
| IL (1) | IL89369A (sk) |
| NZ (1) | NZ228065A (sk) |
| PL (3) | PL160732B1 (sk) |
| SK (1) | SK112489A3 (sk) |
| ZA (1) | ZA891408B (sk) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3826058A1 (de) * | 1988-07-30 | 1990-02-08 | Bayer Ag | Mittel gegen fischparasiten |
| US5214043A (en) * | 1989-01-09 | 1993-05-25 | Bayer Aktiengesellschaft | Parasiticidal substituted hexahydro-1,2,4-triazinediones |
| US5070091A (en) * | 1989-01-09 | 1991-12-03 | Bayer Aktiengesellschaft | Substituted 1,2,4-triazinediones useful against protozoa in insects |
| EP0377903A3 (de) * | 1989-01-09 | 1991-07-17 | Bayer Ag | Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
| CN1044905A (zh) * | 1989-02-16 | 1990-08-29 | 赫彻斯特股份公司 | 鱼和昆虫寄生虫对抗剂 |
| DE4030042A1 (de) * | 1990-05-17 | 1991-11-21 | Bayer Ag | Verwendung von substituierten 1,2,4-triazindionen |
| JP3288132B2 (ja) * | 1992-06-25 | 2002-06-04 | サントリー株式会社 | 置換１，２，４−トリアジン−３，５−ジオンおよびそれを有効成分とする抗コクシジウム組成物 |
| DE4427529A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Verfahren zur Herstellung von 1,2,4-Triazin-3,5-dionen |
| US5883095A (en) * | 1997-08-07 | 1999-03-16 | University Of Kentucky Research Foundation | Formulations and methods to treat and prevent equine protozoal myeloencephalitis |
| US5830893A (en) * | 1997-04-23 | 1998-11-03 | Mortar & Pestle Veterinary Pharmacy, Inc. | Treatment of equine protozoan myeloencephalitis using triazinediones |
| AU766542B2 (en) * | 1998-10-08 | 2003-10-16 | New Ace Research Company | Novel compositions and methods for prevention and treatment of protozoal disease |
| DE19958388A1 (de) * | 1999-12-03 | 2001-06-07 | Bayer Ag | Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten |
| US6429211B1 (en) | 2000-05-23 | 2002-08-06 | Bayer Corporation | Praziquantel compounds for treating diseases due to Sarcocystis Neospora Toxoplasma and Isospora |
| HUP0400982A2 (en) * | 2004-05-17 | 2006-08-28 | Chemor Kutato | New veterinary product for honeybees |
| DE102009038950A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue antiparasitäre Kombination von Wirkstoffen |
| DE102009038949A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue Verwendung von heterocyclisch substituierten 1,2,4-Triazindionen |
| CN116535362A (zh) * | 2023-07-05 | 2023-08-04 | 山东国邦药业有限公司 | 一种沙咪珠利a晶型及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1448696A (en) * | 1973-05-29 | 1976-09-08 | Pfizer | 2-phqnyl-astriazine-3,4-2h,4h-diones |
| DE2532363A1 (de) * | 1975-07-19 | 1977-02-03 | Bayer Ag | Substituierte 2-phenyl-1,2,4- triazin-3,5(2h,4h)-dione, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2722537A1 (de) * | 1977-05-18 | 1978-11-23 | Hoechst Ag | Substituierte 2-phenyl-1,2,4-triazin-3,5-(2h,4h)-dione, verfahren zu ihrer herstellung und sie enthaltende coccidiostatische mittel |
| DE3405241A1 (de) * | 1984-02-15 | 1985-08-29 | Bayer Ag, 5090 Leverkusen | 1-/4-(benzothia- oder -oxazol-2-ylthio- oder -2-yloxy) phenyl/-1,3,5-triazin-2,4,6-(1h,3h,5h)-trione, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3408768A1 (de) * | 1984-03-09 | 1985-09-12 | Bayer Ag, 5090 Leverkusen | Immunstimulierende mittel |
-
1988
- 1988-02-24 DE DE3805660A patent/DE3805660A1/de not_active Withdrawn
-
1989
- 1989-02-13 AT AT89102429T patent/ATE104296T1/de not_active IP Right Cessation
- 1989-02-13 ES ES89102429T patent/ES2063063T3/es not_active Expired - Lifetime
- 1989-02-13 DE DE58907421T patent/DE58907421D1/de not_active Expired - Lifetime
- 1989-02-13 EP EP89102429A patent/EP0330041B1/de not_active Expired - Lifetime
- 1989-02-14 US US07/310,809 patent/US4935423A/en not_active Expired - Lifetime
- 1989-02-20 JP JP1038483A patent/JP2703607B2/ja not_active Expired - Lifetime
- 1989-02-21 CZ CS891124A patent/CZ282916B6/cs not_active IP Right Cessation
- 1989-02-21 NZ NZ228065A patent/NZ228065A/xx unknown
- 1989-02-21 IL IL89369A patent/IL89369A/xx not_active IP Right Cessation
- 1989-02-21 SK SK1124-89A patent/SK112489A3/sk unknown
- 1989-02-22 CA CA000591728A patent/CA1328868C/en not_active Expired - Lifetime
- 1989-02-22 DD DD89325953A patent/DD284012A5/de not_active IP Right Cessation
- 1989-02-22 KR KR1019890002073A patent/KR0133292B1/ko not_active IP Right Cessation
- 1989-02-23 AU AU30256/89A patent/AU606266B2/en not_active Expired
- 1989-02-23 HU HU73/89A patent/HU215836B/hu unknown
- 1989-02-23 ZA ZA891408A patent/ZA891408B/xx unknown
- 1989-02-23 PL PL1989281903A patent/PL160732B1/pl unknown
- 1989-02-23 BR BR898900834A patent/BR8900834A/pt not_active Application Discontinuation
- 1989-02-23 PL PL1989277887A patent/PL160466B1/pl unknown
- 1989-02-23 DK DK198900837A patent/DK175256B1/da not_active IP Right Cessation
- 1989-02-23 PL PL1989281902A patent/PL160587B1/pl unknown
-
1990
- 1990-01-12 US US07/464,089 patent/US4968795A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK83789A (da) | 1989-08-25 |
| KR890012982A (ko) | 1989-09-20 |
| JPH01249772A (ja) | 1989-10-05 |
| IL89369A0 (en) | 1989-09-10 |
| DD284012A5 (de) | 1990-10-31 |
| DE58907421D1 (de) | 1994-05-19 |
| PL160587B1 (pl) | 1993-03-31 |
| CA1328868C (en) | 1994-04-26 |
| CZ112489A3 (en) | 1997-08-13 |
| EP0330041A2 (de) | 1989-08-30 |
| SK279334B6 (sk) | 1998-10-07 |
| HU215836B (hu) | 2000-09-28 |
| JP2703607B2 (ja) | 1998-01-26 |
| PL160732B1 (pl) | 1993-04-30 |
| IL89369A (en) | 1993-01-14 |
| SK112489A3 (en) | 1998-10-07 |
| US4968795A (en) | 1990-11-06 |
| EP0330041A3 (de) | 1991-03-20 |
| AU3025689A (en) | 1989-08-24 |
| ZA891408B (en) | 1989-11-29 |
| KR0133292B1 (ko) | 1998-04-17 |
| CZ282916B6 (cs) | 1997-11-12 |
| BR8900834A (pt) | 1989-10-17 |
| AU606266B2 (en) | 1991-01-31 |
| ATE104296T1 (de) | 1994-04-15 |
| ES2063063T3 (es) | 1995-01-01 |
| PL160466B1 (pl) | 1993-03-31 |
| US4935423A (en) | 1990-06-19 |
| DE3805660A1 (de) | 1989-09-07 |
| DK83789D0 (da) | 1989-02-23 |
| NZ228065A (en) | 1990-09-26 |
| EP0330041B1 (de) | 1994-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |