DK175121B1 - Mersacidin og dennes forbindelses fysiologisk tålelige salte, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelsen, dens anvendelse til fremstilling af lægemidler med antibiotisk virkning samt Bacillus specis Y-85,54728 (DSM 4584) - Google Patents

Mersacidin og dennes forbindelses fysiologisk tålelige salte, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelsen, dens anvendelse til fremstilling af lægemidler med antibiotisk virkning samt Bacillus specis Y-85,54728 (DSM 4584) Download PDF

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Publication number
DK175121B1
DK175121B1 DK198904037A DK403789A DK175121B1 DK 175121 B1 DK175121 B1 DK 175121B1 DK 198904037 A DK198904037 A DK 198904037A DK 403789 A DK403789 A DK 403789A DK 175121 B1 DK175121 B1 DK 175121B1
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DK
Denmark
Prior art keywords
mersacidin
compound
formula
culture
dsm
Prior art date
Application number
DK198904037A
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Danish (da)
English (en)
Other versions
DK403789D0 (da
DK403789A (da
Inventor
Gerhard Seibert
Volker Teetz
Hans-Wolfram Fehlhaber
Sugata Chatterjee
Deepak Kumar Chatterjee
Herbert Kogler
Sukumar Chatterjee
Rajendra Kumar Hariprasad Jani
Richard Helmut Rupp
Bimal Naresh Ganguli
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK403789D0 publication Critical patent/DK403789D0/da
Publication of DK403789A publication Critical patent/DK403789A/da
Application granted granted Critical
Publication of DK175121B1 publication Critical patent/DK175121B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK198904037A 1988-08-17 1989-08-16 Mersacidin og dennes forbindelses fysiologisk tålelige salte, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelsen, dens anvendelse til fremstilling af lægemidler med antibiotisk virkning samt Bacillus specis Y-85,54728 (DSM 4584) DK175121B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3827868A DE3827868A1 (de) 1988-08-17 1988-08-17 Ein neues antibiotikum, mersacidin, ein verfahren zu seiner herstellung und seine verwendung als arzneimittel
DE3827868 1988-08-17

Publications (3)

Publication Number Publication Date
DK403789D0 DK403789D0 (da) 1989-08-16
DK403789A DK403789A (da) 1990-02-18
DK175121B1 true DK175121B1 (da) 2004-06-07

Family

ID=6361001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198904037A DK175121B1 (da) 1988-08-17 1989-08-16 Mersacidin og dennes forbindelses fysiologisk tålelige salte, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelsen, dens anvendelse til fremstilling af lægemidler med antibiotisk virkning samt Bacillus specis Y-85,54728 (DSM 4584)

Country Status (20)

Country Link
US (1) US5112806A (ru)
EP (1) EP0362520B1 (ru)
JP (1) JP2892699B2 (ru)
KR (1) KR0139628B1 (ru)
AT (1) ATE113296T1 (ru)
AU (1) AU613228B2 (ru)
CA (1) CA1338171C (ru)
DE (2) DE3827868A1 (ru)
DK (1) DK175121B1 (ru)
ES (1) ES2064398T3 (ru)
FI (1) FI94648C (ru)
HU (1) HU203906B (ru)
IE (1) IE64706B1 (ru)
IL (1) IL91317A0 (ru)
IN (1) IN167138B (ru)
NO (1) NO174517B (ru)
NZ (1) NZ230303A (ru)
PH (1) PH27179A (ru)
PT (1) PT91468B (ru)
ZA (1) ZA896245B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0700998T3 (da) * 1994-09-12 2004-03-29 Aventis Pharma Gmbh Rekombinant mersacidin samt en fremgangsmåde til fremstilling deraf
US5910479A (en) * 1996-10-18 1999-06-08 Ambi Inc. Method for the treatment of Streptococcus pneumoniae infection
US6861236B2 (en) * 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way
GB0406870D0 (en) 2004-03-26 2004-04-28 Novacta Biosystems Ltd Improvements relating to the production of lantibiotics
WO2007036706A1 (en) * 2005-09-27 2007-04-05 Novacta Biosystems Limited Variants of the lantibiotic mersacidin and their use
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714030D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
AU2010205472B2 (en) 2009-01-14 2013-03-14 Novacta Biosystems Limited Deoxyactagardine derivatives
JP5731407B2 (ja) 2009-02-04 2015-06-10 ノヴァクタ バイオシステムズ リミティッド アクタガルジン誘導体
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
KR102582570B1 (ko) * 2021-03-19 2023-09-22 한국생명공학연구원 유박테리움 칼란데리, 이의 배양액 또는 이의 배양액 추출물을 유효성분으로 포함하는 암 예방 또는 치료용 조성물
EP4404946A1 (en) * 2021-09-22 2024-07-31 BiomEdit, LLC Methods of inhibiting diseases caused by respiratory viruses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493796A (en) * 1980-09-12 1985-01-15 Board Of Trustees, Univ. Of Ill. Didemnins A, B, C, and derivatives thereof, as antiviral agents
JPS61134398A (ja) * 1984-12-06 1986-06-21 Microbial Chem Res Found 新生理活性物質プリパスタチン及びその製造法

Also Published As

Publication number Publication date
EP0362520A3 (de) 1991-10-23
ATE113296T1 (de) 1994-11-15
JP2892699B2 (ja) 1999-05-17
IN167138B (ru) 1990-09-01
FI893842A0 (fi) 1989-08-15
EP0362520A2 (de) 1990-04-11
JPH02142800A (ja) 1990-05-31
KR900003206A (ko) 1990-03-26
NO893288D0 (no) 1989-08-16
FI893842A (fi) 1990-02-18
KR0139628B1 (ko) 1998-07-01
EP0362520B1 (de) 1994-10-26
IE64706B1 (en) 1995-08-23
NO174517B (no) 1994-02-07
AU3996689A (en) 1990-02-22
IE892638L (en) 1990-02-17
DE3827868A1 (de) 1990-02-22
DK403789D0 (da) 1989-08-16
ES2064398T3 (es) 1995-02-01
DE58908558D1 (de) 1994-12-01
PT91468A (pt) 1990-03-08
NZ230303A (en) 1992-06-25
HUT55054A (en) 1991-04-29
CA1338171C (en) 1996-03-19
FI94648C (fi) 1995-10-10
IL91317A0 (en) 1990-03-19
NO174517C (ru) 1994-05-18
US5112806A (en) 1992-05-12
FI94648B (fi) 1995-06-30
PT91468B (pt) 1995-05-04
HU203906B (en) 1991-10-28
ZA896245B (en) 1990-04-25
NO893288L (no) 1990-02-19
DK403789A (da) 1990-02-18
PH27179A (en) 1993-04-02
AU613228B2 (en) 1991-07-25

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