DK173724B1 - Analysemetode og diagnosesæt til undersøgelse af unormal lipidmetabolisme - Google Patents

Analysemetode og diagnosesæt til undersøgelse af unormal lipidmetabolisme Download PDF

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Publication number
DK173724B1
DK173724B1 DK198705092A DK509287A DK173724B1 DK 173724 B1 DK173724 B1 DK 173724B1 DK 198705092 A DK198705092 A DK 198705092A DK 509287 A DK509287 A DK 509287A DK 173724 B1 DK173724 B1 DK 173724B1
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DK
Denmark
Prior art keywords
apo
lipoprotein
solid
bound
molecules
Prior art date
Application number
DK198705092A
Other languages
Danish (da)
English (en)
Other versions
DK509287A (da
DK509287D0 (da
Inventor
Steven Young
Richard S Smith
Linda K Curtiss
Doreen M Hogle
Joseph L Witztum
Original Assignee
Scripps Clinic Res
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Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK509287D0 publication Critical patent/DK509287D0/da
Publication of DK509287A publication Critical patent/DK509287A/da
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Publication of DK173724B1 publication Critical patent/DK173724B1/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/044Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/948Microorganisms using viruses or cell lines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809Fused cells, e.g. hybridoma

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Fats And Perfumes (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
DK198705092A 1986-09-29 1987-09-28 Analysemetode og diagnosesæt til undersøgelse af unormal lipidmetabolisme DK173724B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91314086 1986-09-29
US06/913,140 US4828986A (en) 1986-09-29 1986-09-29 Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Publications (3)

Publication Number Publication Date
DK509287D0 DK509287D0 (da) 1987-09-28
DK509287A DK509287A (da) 1988-03-30
DK173724B1 true DK173724B1 (da) 2001-07-30

Family

ID=25432962

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198705092A DK173724B1 (da) 1986-09-29 1987-09-28 Analysemetode og diagnosesæt til undersøgelse af unormal lipidmetabolisme

Country Status (17)

Country Link
US (1) US4828986A (ja)
EP (1) EP0262854B1 (ja)
JP (1) JP2656774B2 (ja)
AT (1) ATE85435T1 (ja)
AU (1) AU611096B2 (ja)
CA (1) CA1285869C (ja)
DE (1) DE3783991T2 (ja)
DK (1) DK173724B1 (ja)
ES (1) ES2053555T3 (ja)
FI (1) FI89214C (ja)
GR (1) GR3008027T3 (ja)
IE (1) IE60119B1 (ja)
IL (1) IL83938A (ja)
NO (1) NO173902C (ja)
NZ (1) NZ221941A (ja)
PT (1) PT85827B (ja)
ZA (1) ZA876970B (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257778B1 (en) * 1986-08-06 1995-03-22 Scripps Clinic And Research Foundation Apolipoprotein b-specific monoclonal antibodies produced by two novel hybridomas
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
AU621575B2 (en) * 1987-11-02 1992-03-19 Scripps Clinic And Research Foundation Diagnostic methods and systems for quantifying apo ai
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
US5179008A (en) * 1989-02-09 1993-01-12 Wisconsin Alumni Research Foundation Hybridoma and monoclonal antibody to FHAP
US5473039A (en) * 1989-08-18 1995-12-05 The Scripps Research Institute Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
US5168045A (en) * 1989-08-18 1992-12-01 The Scripps Research Institute Diagnostic systems and methods using polypeptide analogs of apolipoprotein e
AU662885B2 (en) * 1990-06-07 1995-09-21 Scripps Research Institute, The APO AI polypeptides, antibodies, and immunoassays
WO1992009893A1 (en) * 1990-11-29 1992-06-11 Carbaugh John E DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS AND METHODS FOR LIPOPROTEIN(a)
WO1992010760A1 (en) * 1990-11-30 1992-06-25 Monoclonetics International, Incorporated Methods for the diagnosis of chronic lower back and cervical pain
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
US5408038A (en) * 1991-10-09 1995-04-18 The Scripps Research Institute Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides
JPH08501633A (ja) * 1992-09-24 1996-02-20 パーセプティブ バイオシステムズ インコーポレイテッド Ldlの定量
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US6248539B1 (en) 1997-09-05 2001-06-19 The Scripps Research Institute Porous semiconductor-based optical interferometric sensor
US6309844B1 (en) * 1997-10-15 2001-10-30 Fujirebio Inc. Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same
AT5044U1 (de) * 2001-05-10 2002-02-25 Medsystems Diagnostics Gmbh Quantitativer einschritt immuntest in lyophilisierter form
CN100516878C (zh) * 2001-07-12 2009-07-22 协和美帝克斯股份有限公司 变性脂蛋白的定量方法及定量用试剂
US7781171B2 (en) 2003-10-15 2010-08-24 Daiichi Pure Chemicals Co., Ltd. Mehod of pretreating sample and immunological assay method using the same
ATE427490T1 (de) * 2003-10-15 2009-04-15 Sekisui Medical Co Ltd Verfahren zur probenvorbehandlung sowie immunologisches testverfahren unter verwendung davon
US7521248B2 (en) * 2007-04-20 2009-04-21 Atherotech, Inc. Apo B measurement system and method
KR102072251B1 (ko) 2011-11-11 2020-01-31 엑시스-시일드 에이에스 혈액 샘플 분석 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2061282B (en) * 1979-10-22 1983-03-30 Symphar Sa Method for the clinical separation of a-and lipoproteins and kit for carrying out this method
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質b100抗体
JPS60253871A (ja) * 1984-05-30 1985-12-14 Nippon Koutai Kenkyusho:Kk 抗アポa−1抗体
JPS62501770A (ja) * 1984-12-31 1987-07-16 ゾマ、コーポレーション ヒトアポリポタンパク質のペプチドフラグメント、種特異性抗体及び使用方法
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins

Also Published As

Publication number Publication date
PT85827B (pt) 1990-08-31
FI874253A0 (fi) 1987-09-28
IL83938A0 (en) 1988-02-29
ZA876970B (en) 1988-03-21
FI89214B (fi) 1993-05-14
AU7902887A (en) 1988-03-31
AU611096B2 (en) 1991-06-06
IE872605L (en) 1988-03-29
JP2656774B2 (ja) 1997-09-24
FI874253A (fi) 1988-03-30
DE3783991D1 (de) 1993-03-18
IL83938A (en) 1991-12-15
NO173902B (no) 1993-11-08
PT85827A (en) 1987-10-01
ES2053555T3 (es) 1994-08-01
FI89214C (fi) 1993-08-25
ATE85435T1 (de) 1993-02-15
JPS63277968A (ja) 1988-11-15
DE3783991T2 (de) 1993-06-09
NZ221941A (en) 1989-05-29
DK509287A (da) 1988-03-30
CA1285869C (en) 1991-07-09
IE60119B1 (en) 1994-06-01
US4828986A (en) 1989-05-09
GR3008027T3 (ja) 1993-09-30
EP0262854A3 (en) 1989-12-06
EP0262854A2 (en) 1988-04-06
DK509287D0 (da) 1987-09-28
NO874056D0 (no) 1987-09-28
NO874056L (no) 1988-03-30
EP0262854B1 (en) 1993-02-03
NO173902C (no) 1994-02-16

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired