DE3783991T2 - Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels. - Google Patents

Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels.

Info

Publication number
DE3783991T2
DE3783991T2 DE8787308392T DE3783991T DE3783991T2 DE 3783991 T2 DE3783991 T2 DE 3783991T2 DE 8787308392 T DE8787308392 T DE 8787308392T DE 3783991 T DE3783991 T DE 3783991T DE 3783991 T2 DE3783991 T2 DE 3783991T2
Authority
DE
Germany
Prior art keywords
determining
fati
metabolism
abnormal
test method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787308392T
Other languages
English (en)
Other versions
DE3783991D1 (de
Inventor
Richard S Smith
Doreen M Hogle
Linda K Curtiss
Joseph L Witztum
Stephen Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Application granted granted Critical
Publication of DE3783991D1 publication Critical patent/DE3783991D1/de
Publication of DE3783991T2 publication Critical patent/DE3783991T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
DE8787308392T 1986-09-29 1987-09-22 Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels. Expired - Lifetime DE3783991T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/913,140 US4828986A (en) 1986-09-29 1986-09-29 Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Publications (2)

Publication Number Publication Date
DE3783991D1 DE3783991D1 (de) 1993-03-18
DE3783991T2 true DE3783991T2 (de) 1993-06-09

Family

ID=25432962

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787308392T Expired - Lifetime DE3783991T2 (de) 1986-09-29 1987-09-22 Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels.

Country Status (17)

Country Link
US (1) US4828986A (de)
EP (1) EP0262854B1 (de)
JP (1) JP2656774B2 (de)
AT (1) ATE85435T1 (de)
AU (1) AU611096B2 (de)
CA (1) CA1285869C (de)
DE (1) DE3783991T2 (de)
DK (1) DK173724B1 (de)
ES (1) ES2053555T3 (de)
FI (1) FI89214C (de)
GR (1) GR3008027T3 (de)
IE (1) IE60119B1 (de)
IL (1) IL83938A (de)
NO (1) NO173902C (de)
NZ (1) NZ221941A (de)
PT (1) PT85827B (de)
ZA (1) ZA876970B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE120233T1 (de) * 1986-08-06 1995-04-15 Scripps Clinic Res Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden.
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
AU621575B2 (en) * 1987-11-02 1992-03-19 Scripps Clinic And Research Foundation Diagnostic methods and systems for quantifying apo ai
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
US5179008A (en) * 1989-02-09 1993-01-12 Wisconsin Alumni Research Foundation Hybridoma and monoclonal antibody to FHAP
US5473039A (en) * 1989-08-18 1995-12-05 The Scripps Research Institute Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
US5168045A (en) * 1989-08-18 1992-12-01 The Scripps Research Institute Diagnostic systems and methods using polypeptide analogs of apolipoprotein e
AU662885B2 (en) * 1990-06-07 1995-09-21 Scripps Research Institute, The APO AI polypeptides, antibodies, and immunoassays
AU9088891A (en) * 1990-11-29 1992-06-25 John E. Carbaugh Diagnostic and therapeutic compositions and methods for lipoprotein(a)
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
DK0559795T3 (da) * 1990-11-30 1996-01-29 Monoclonetics Int Fremgangsmåder til diagnosticering af kroniske smerter i lænderegionen og halshvrivelsøjlen
US5408038A (en) * 1991-10-09 1995-04-18 The Scripps Research Institute Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides
AU4924193A (en) * 1992-09-24 1994-04-12 Perseptive Biosystems, Inc. Quantitative measurement of ldl
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US6248539B1 (en) 1997-09-05 2001-06-19 The Scripps Research Institute Porous semiconductor-based optical interferometric sensor
US6309844B1 (en) * 1997-10-15 2001-10-30 Fujirebio Inc. Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same
AT5044U1 (de) * 2001-05-10 2002-02-25 Medsystems Diagnostics Gmbh Quantitativer einschritt immuntest in lyophilisierter form
DE60237455D1 (de) * 2001-07-12 2010-10-07 Kyowa Medex Co Ltd Verfahren zur quantifizierung von denaturiertem lipoprotein
ES2323271T3 (es) * 2003-10-15 2009-07-10 Sekisui Medical Co., Ltd. Metodo de pretratamiento de una muestra y metodo de dosificacion inmunologica utilizado.
US7781171B2 (en) 2003-10-15 2010-08-24 Daiichi Pure Chemicals Co., Ltd. Mehod of pretreating sample and immunological assay method using the same
US7521248B2 (en) * 2007-04-20 2009-04-21 Atherotech, Inc. Apo B measurement system and method
EP3435089A1 (de) 2011-11-11 2019-01-30 Axis-Shield AS Bestimmung von nicht-hdl cholesterin in blut

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2061282B (en) * 1979-10-22 1983-03-30 Symphar Sa Method for the clinical separation of a-and lipoproteins and kit for carrying out this method
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60253871A (ja) * 1984-05-30 1985-12-14 Nippon Koutai Kenkyusho:Kk 抗アポａ−１抗体
JPS62501770A (ja) * 1984-12-31 1987-07-16 ゾマ、コーポレーション ヒトアポリポタンパク質のペプチドフラグメント、種特異性抗体及び使用方法
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins

Also Published As

Publication number Publication date
EP0262854A2 (de) 1988-04-06
JPS63277968A (ja) 1988-11-15
ZA876970B (en) 1988-03-21
AU611096B2 (en) 1991-06-06
FI89214B (fi) 1993-05-14
PT85827A (en) 1987-10-01
AU7902887A (en) 1988-03-31
NO173902B (no) 1993-11-08
EP0262854B1 (de) 1993-02-03
NO874056D0 (no) 1987-09-28
EP0262854A3 (en) 1989-12-06
NZ221941A (en) 1989-05-29
FI89214C (fi) 1993-08-25
IL83938A0 (en) 1988-02-29
DK173724B1 (da) 2001-07-30
IE872605L (en) 1988-03-29
JP2656774B2 (ja) 1997-09-24
ES2053555T3 (es) 1994-08-01
US4828986A (en) 1989-05-09
DE3783991D1 (de) 1993-03-18
NO874056L (no) 1988-03-30
ATE85435T1 (de) 1993-02-15
DK509287A (da) 1988-03-30
IE60119B1 (en) 1994-06-01
PT85827B (pt) 1990-08-31
NO173902C (no) 1994-02-16
CA1285869C (en) 1991-07-09
IL83938A (en) 1991-12-15
FI874253A0 (fi) 1987-09-28
FI874253A (fi) 1988-03-30
GR3008027T3 (de) 1993-09-30
DK509287D0 (da) 1987-09-28

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