DK1734368T3 - Annexin-autoantistoffer anvendt som markörer for lungecancer - Google Patents

Annexin-autoantistoffer anvendt som markörer for lungecancer

Info

Publication number
DK1734368T3
DK1734368T3 DK06075982T DK06075982T DK1734368T3 DK 1734368 T3 DK1734368 T3 DK 1734368T3 DK 06075982 T DK06075982 T DK 06075982T DK 06075982 T DK06075982 T DK 06075982T DK 1734368 T3 DK1734368 T3 DK 1734368T3
Authority
DK
Denmark
Prior art keywords
markers
lung cancer
annexin
annexin autoantibodies
autoantibodies used
Prior art date
Application number
DK06075982T
Other languages
Danish (da)
English (en)
Inventor
Samir M Hanash
David Misek
Robert Hinderer
David Beer
Franck Brichory
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of DK1734368T3 publication Critical patent/DK1734368T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4718—Lipocortins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK06075982T 1999-08-06 2000-08-04 Annexin-autoantistoffer anvendt som markörer for lungecancer DK1734368T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/370,337 US6645465B2 (en) 1999-08-06 1999-08-06 Annexin proteins and autoantibodies as serum markers for cancer
PCT/US2000/021514 WO2001011372A1 (fr) 1999-08-06 2000-08-04 Annexines et anticorps utilises comme marqueurs pour le cancer

Publications (1)

Publication Number Publication Date
DK1734368T3 true DK1734368T3 (da) 2009-06-02

Family

ID=23459219

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06075982T DK1734368T3 (da) 1999-08-06 2000-08-04 Annexin-autoantistoffer anvendt som markörer for lungecancer
DK00952594T DK1200832T3 (da) 1999-08-06 2000-08-04 Annexiner og autoantistoffer anvendt som markörer for lungecancer og ösofageal cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK00952594T DK1200832T3 (da) 1999-08-06 2000-08-04 Annexiner og autoantistoffer anvendt som markörer for lungecancer og ösofageal cancer

Country Status (10)

Country Link
US (5) US6645465B2 (fr)
EP (3) EP1734368B1 (fr)
JP (1) JP4594575B2 (fr)
AT (3) ATE529751T1 (fr)
AU (1) AU780772B2 (fr)
CA (1) CA2380398C (fr)
DE (2) DE60041839D1 (fr)
DK (2) DK1734368T3 (fr)
ES (2) ES2320585T3 (fr)
WO (1) WO2001011372A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810040D0 (en) * 1998-05-11 1998-07-08 Univ Nottingham Blood borne tumour markers
GB9827228D0 (en) * 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
US6645465B2 (en) * 1999-08-06 2003-11-11 Michigan, University Of The Regents Annexin proteins and autoantibodies as serum markers for cancer
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
US6869934B2 (en) * 2000-07-21 2005-03-22 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Method of purifying calcium ion-binding protein
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US7635680B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US7645739B2 (en) 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
EP1379266B1 (fr) 2001-02-21 2007-04-18 SurroMed, Inc. Annexines modifiees et prevention de la thrombose
US7214498B2 (en) * 2001-03-23 2007-05-08 Benaroya Research Institute At Virginia Mason Tumor associated antigens and methods of using the same
EP1428028A2 (fr) * 2001-09-14 2004-06-16 Reinhard Zeidler Identification d'antigenes par precipitation provoquee au moyen d'anticorps xenogenes, allogenes ou autologues
US20050221305A1 (en) * 2001-11-09 2005-10-06 Benaroya Research Institute At Virginia Mason Antigen panels and methods of using the same
GB2424273B (en) * 2002-11-14 2007-06-27 Univ Nottingham Method for preparing tumour marker protein
EP1601969A2 (fr) 2003-03-08 2005-12-07 Auvation Ltd Marqueurs cancereux
CA2555866A1 (fr) * 2004-02-16 2005-08-25 Proteosys Ag Marqueur diagnostique pour le cancer
EP1756572B1 (fr) * 2004-05-13 2016-02-24 Centre National De La Recherche Scientifique (Cnrs) Dispositif liant une entite cible a une entite appat et procedes de detection l'utilisant
US7943294B2 (en) * 2004-07-30 2011-05-17 Hologic, Inc. Methods for detecting oncofetal fibronectin
RU2277242C2 (ru) * 2004-08-23 2006-05-27 Александр Владимирович Балюра Способ диагностики опухолей
JP4521575B2 (ja) * 2005-03-17 2010-08-11 国立大学法人 千葉大学 特発性肺線維症の検出マーカー、検出キット及び検出方法
EP1724585A1 (fr) * 2005-05-21 2006-11-22 ProteoSys AG Annexin pour l'évaluation du risque de cancer
EP1724586A3 (fr) * 2005-05-21 2007-07-04 ProteoSys AG Annexine pour l'évaluation du risque de cancer
GB2426581A (en) * 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
RU2636532C2 (ru) 2005-05-27 2017-11-23 Онкиммьюн Лимитед Улучшенные способы иммуноанализа
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
JP5405111B2 (ja) * 2005-09-26 2014-02-05 ウルリヒ ルース Ｔｓｈ受容体及び新規ｔｓｈ受容体キメラに対する自己免疫抗体検出方法
BRPI0619712A2 (pt) * 2005-11-10 2011-10-11 Univ Kentucky dispositivo para a identificação de um paciente como um candidato para testes radiográficos para o cáncer do pulmão, composição para detectar radiograficamente um cáncer do pulmão de estágio adiantado, dispositivo para o ensaio do cáncer do pulmão, uso de um painel, e, dispositivo de diagnóstico para a detecção do cáncer do pulmão
US9347945B2 (en) * 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
CN101490550A (zh) * 2006-07-08 2009-07-22 肯塔基大学研究基金会 肺癌诊断分析
CN101632020B (zh) * 2006-09-13 2013-11-27 昂西免疫有限公司 改进的免疫测定方法
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
MX2009004460A (es) * 2006-10-26 2009-07-09 Abbott Lab Inmunoensayo de analitos en muestras que contienen anticuerpos anti-analito endogenos.
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
US20090047689A1 (en) * 2007-06-20 2009-02-19 John Kolman Autoantigen biomarkers for early diagnosis of lung adenocarcinoma
GB0725239D0 (en) * 2007-12-24 2008-02-06 Oncimmune Ltd Calibrator for autoantibody assay
JP2012500964A (ja) * 2008-05-09 2012-01-12 デューク ユニバーシティ 癌の検出と治療における自己抗体
US9581599B2 (en) 2010-06-28 2017-02-28 The Board Of Regents Of The University Of Texas System Diagnosis of benign and cancerous growths by measuring circulating tumor stem cells and serum AnnexinA2
WO2012048190A1 (fr) * 2010-10-08 2012-04-12 Regents Of The University Of Minnesota Composition d'annexine ii et procédés
KR20150010882A (ko) * 2013-07-19 2015-01-29 삼성전자주식회사 아넥신 Ａ2 결합단백질, ｐ53 단백질 및 ｐ18 단백질을 포함하는 융합 단백질 및 이를 포함하는 암의 예방 또는 치료용 조성물
US20160291025A1 (en) * 2013-09-18 2016-10-06 Adelaide Research & Innovation Pty Ltd Autoantibody biomarkers of ovarian cancer
CA2930567C (fr) 2013-11-13 2023-09-26 Regents Of The University Of Minnesota Compositions de variants d'annexine ii et methodes
CN104407151B (zh) * 2014-11-19 2016-06-08 汕头大学医学院 Kindlin-2，Myosin-9和Annexin II三蛋白联合预测食管鳞癌患者预后试剂盒
CN113721021B (zh) * 2021-09-16 2023-07-07 郑州大学 Prkcz自身抗体在食管鳞癌辅助诊断中的应用
CN116539885B (zh) * 2023-07-06 2023-09-29 上海秤信生物科技有限公司 用于乳腺癌早期检测的肿瘤自身抗原/抗体组合及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02496A (ja) * 1987-12-24 1990-01-05 Nippon Shinyaku Co Ltd モノクローナル抗体、製法、及び利用法
DE4012341A1 (de) * 1990-04-18 1991-10-24 Behringwerke Ag Monoklonale antikoerper gegen pp4, verfahren zu ihrer herstellung und ihre verwendung
DE4040306A1 (de) 1990-12-17 1992-06-25 Behringwerke Ag Verfahren zur bestimmung von antikoerpern gegen lipocortine
US5405749A (en) * 1991-12-06 1995-04-11 Polans; Arthur S. Method for identifying and purifying a cancer associated retinopathy autoantigen, and testing patient serum for the autoantibody to the autoantigen
JPH0772149A (ja) * 1993-06-30 1995-03-17 Nippon Shinyaku Co Ltd 肝癌又は肝硬変の診断薬及び診断法
JPH0772147A (ja) * 1993-07-02 1995-03-17 Noboru Kaneko 抗アネキシンｖ抗体並びに該抗体の製法及び利用
EP0651253A1 (fr) * 1993-11-02 1995-05-03 Abbott Laboratories Essai immunologique pour la detéction des autoanticorps humaines
US5658877A (en) * 1995-05-18 1997-08-19 Wisconsin Alumni Research Foundation Method to treat endotoxin effects by administration of 33 kilodalton phospholipid binding protein
AU8267398A (en) 1997-06-26 1999-01-19 Regents Of The University Of Michigan, The Method for identification of tumor antigens with autoantibodies in serum
CA2274776C (fr) * 1997-10-08 2008-11-25 Noboru Kaneko Procede d'analyse de l'annexine v dans l'urine et utilisation
AU762512B2 (en) * 1998-12-28 2003-06-26 Atossa Genetics, Inc. Devices, methods and systems for collecting material from a breast duct
US6645465B2 (en) * 1999-08-06 2003-11-11 Michigan, University Of The Regents Annexin proteins and autoantibodies as serum markers for cancer

Also Published As

Publication number Publication date
WO2001011372A9 (fr) 2002-04-11
US20070037227A1 (en) 2007-02-15
ATE426167T1 (de) 2009-04-15
DE60028040T2 (de) 2006-11-23
US20060275845A1 (en) 2006-12-07
WO2001011372A1 (fr) 2001-02-15
US7955602B2 (en) 2011-06-07
EP1734368A3 (fr) 2007-03-07
US6645465B2 (en) 2003-11-11
EP1734368A2 (fr) 2006-12-20
ES2259609T3 (es) 2006-10-16
EP2051079A2 (fr) 2009-04-22
EP1734368B1 (fr) 2009-03-18
ATE326699T1 (de) 2006-06-15
ATE529751T1 (de) 2011-11-15
AU6526200A (en) 2001-03-05
US20040048320A1 (en) 2004-03-11
CA2380398A1 (fr) 2001-02-15
US20100330587A1 (en) 2010-12-30
DE60041839D1 (de) 2009-04-30
EP2051079A3 (fr) 2009-06-10
AU780772B2 (en) 2005-04-14
CA2380398C (fr) 2017-01-31
US7759081B2 (en) 2010-07-20
DK1200832T3 (da) 2006-09-18
JP4594575B2 (ja) 2010-12-08
EP1200832B1 (fr) 2006-05-17
EP2051079B1 (fr) 2011-10-19
EP1200832A1 (fr) 2002-05-02
ES2320585T3 (es) 2009-05-25
JP2003535309A (ja) 2003-11-25
US20020168696A1 (en) 2002-11-14
DE60028040D1 (de) 2006-06-22

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