DK172619B1 - Fremgangsmåde til isolering af immunogene præparater af herpes simplex virus type 1 og type 2, fremgangsmåde til fremstill - Google Patents

Fremgangsmåde til isolering af immunogene præparater af herpes simplex virus type 1 og type 2, fremgangsmåde til fremstill Download PDF

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Publication number
DK172619B1
DK172619B1 DK198304790A DK479083A DK172619B1 DK 172619 B1 DK172619 B1 DK 172619B1 DK 198304790 A DK198304790 A DK 198304790A DK 479083 A DK479083 A DK 479083A DK 172619 B1 DK172619 B1 DK 172619B1
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Denmark
Prior art keywords
amino acid
herpes simplex
simplex virus
asp
leu
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DK198304790A
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Danish (da)
English (en)
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DK479083D0 (da
DK479083A (da
Inventor
Gary H Cohen
Roselyn J Eisenberg
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University Patents Inc
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Publication of DK479083D0 publication Critical patent/DK479083D0/da
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56994Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/22Viral peptide or viral protein
    • Y10S930/224Herpes related

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK198304790A 1982-02-18 1983-10-17 Fremgangsmåde til isolering af immunogene præparater af herpes simplex virus type 1 og type 2, fremgangsmåde til fremstill DK172619B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US35002182A 1982-02-18 1982-02-18
US35002182 1982-02-18
US06/463,141 US4762708A (en) 1982-02-18 1983-02-04 Materials and methods for herpes simplex virus vaccination
US46314183 1983-02-04
US8300182 1983-02-14
PCT/US1983/000182 WO1983002897A1 (en) 1982-02-18 1983-02-14 Materials and methods for herpes simplex virus vaccination

Publications (3)

Publication Number Publication Date
DK479083D0 DK479083D0 (da) 1983-10-17
DK479083A DK479083A (da) 1983-10-17
DK172619B1 true DK172619B1 (da) 1999-03-01

Family

ID=26996451

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198304790A DK172619B1 (da) 1982-02-18 1983-10-17 Fremgangsmåde til isolering af immunogene præparater af herpes simplex virus type 1 og type 2, fremgangsmåde til fremstill

Country Status (20)

Country Link
US (1) US4762708A (fi)
EP (1) EP0101506B1 (fi)
JP (3) JP2665332B2 (fi)
KR (1) KR910006889B1 (fi)
AR (1) AR231496A1 (fi)
AT (1) ATE54827T1 (fi)
AU (1) AU554710B2 (fi)
CA (1) CA1236774A (fi)
DE (1) DE3381761D1 (fi)
DK (1) DK172619B1 (fi)
ES (1) ES519875A0 (fi)
FI (2) FI73885C (fi)
GR (1) GR77900B (fi)
HU (1) HU195734B (fi)
IE (1) IE56479B1 (fi)
IL (5) IL80896A (fi)
NO (2) NO162366B (fi)
NZ (1) NZ220771A (fi)
PH (1) PH25689A (fi)
WO (1) WO1983002897A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540669A (en) * 1980-09-11 1985-09-10 Merck & Co., Inc. Herpes simplex type I subunit vaccine
US5149660A (en) * 1982-02-18 1992-09-22 University Patents, Inc. Diagnostic reagents relating to herpes simplex virus
NZ209308A (en) * 1983-08-30 1991-08-27 Genentech Inc Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein
NZ209307A (en) * 1983-08-30 1990-07-26 Genentech Inc Diagnostic product: antigenic peptide produced by recombinant dna techniques
US7264817B1 (en) 1983-08-30 2007-09-04 Genentech, Inc. Immunogenic composition based on a truncated derivative of a membrane bound protein and process for making it
JPS6051120A (ja) * 1983-08-31 1985-03-22 Chemo Sero Therapeut Res Inst 単純ヘルペスサブユニットワクチン
US5171568A (en) * 1984-04-06 1992-12-15 Chiron Corporation Recombinant herpes simplex gb-gd vaccine
US5612041A (en) * 1984-07-17 1997-03-18 Chiron Corporation Recombinant herpes simplex gD vaccine
JPS6153226A (ja) * 1984-08-24 1986-03-17 Chemo Sero Therapeut Res Inst 単純ヘルペスサブユニツトワクチンの精製方法
ATE72123T1 (de) * 1985-04-19 1992-02-15 Wistar Inst Impfstoff fuer die erzeugung einer gegen ein virus schuetzenden immunogenen t-zellen-antwort.
GB8605390D0 (en) * 1986-03-05 1986-04-09 Univ Birmingham Live herpes simplex vaccine
EP0471778A1 (en) * 1989-05-12 1992-02-26 Ciba Corning Diagnostics Corp. Herpes simplex virus type 2-glycoprotein g proteins and polypeptides
GB9105992D0 (en) * 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccine
US5654174A (en) * 1995-07-07 1997-08-05 Competitive Technologies, Inc. Herpes simplex virus glycoprotein D variants
AU2001286407A1 (en) * 2000-08-01 2002-03-04 University Of Pittsburgh Of The Commonwealth System Of Higher Education Antiviral compounds derived from the hsv gd protein and methods
US20030219448A1 (en) * 2002-05-24 2003-11-27 Cedars-Sinai Medical Center Peptide epitope-based vaccine for treating herpes simplex virus infections and related diseases
DK1523582T3 (da) * 2002-07-18 2009-03-02 Univ Washington Hurtig, effektiv rensning af HSV-specifikke T-lymfocytter samt HSV-antigener identificeret derved
AU2004274430A1 (en) * 2003-09-12 2005-03-31 Antigenics, Inc. Vaccine for treatment and prevention of herpes simplex virus infection
US8865185B2 (en) 2006-09-08 2014-10-21 The Trustees Of The University Of Pennsylvania Methods of use for HSV-1 and HSV-2 vaccines
CA2663109A1 (en) * 2006-09-08 2008-03-13 The Trustees Of The University Of Pennsylvania Hsv-1 and hsv-2 vaccines and methods of use thereof
US10478490B2 (en) * 2006-12-28 2019-11-19 The Trustees Of The University Of Pennsylvania Herpes simplex virus combined subunit vaccines and methods of use thereof
US20130028925A1 (en) * 2006-12-28 2013-01-31 Harvey Friedman Herpes simplex virus combined subunit vaccines and methods of use thereof
US8057804B2 (en) * 2006-12-28 2011-11-15 The Trustees Of The University Of Pennsylvania Herpes simplex virus combined subunit vaccines and methods of use thereof
JP6144448B2 (ja) * 2006-12-28 2017-06-07 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 単純ヘルペスウイルス複合サブユニットワクチンおよびその使用方法
US9089537B2 (en) 2010-02-26 2015-07-28 The Trustees Of The University Of Pennslyvania Subunit vaccines for herpes viruses and methods of use
EP2694542A4 (en) * 2011-04-08 2014-10-08 Univ Duke HERPES SIMPLEX VIRUS
RS57420B1 (sr) 2012-05-16 2018-09-28 Immune Design Corp Vakcine za hsv-2

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374127A (en) * 1977-09-19 1983-02-15 Merck & Co., Inc. Herpes sub unit vaccine
ES487106A0 (es) * 1978-12-22 1981-05-16 Biogen Nv Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv

Also Published As

Publication number Publication date
JPH0797396A (ja) 1995-04-11
FI833768A0 (fi) 1983-10-17
ES8406199A1 (es) 1984-08-01
JP2669594B2 (ja) 1997-10-29
FI83880B (fi) 1991-05-31
EP0101506B1 (en) 1990-07-25
NO172745B (no) 1993-05-24
WO1983002897A1 (en) 1983-09-01
JPS59500216A (ja) 1984-02-16
FI73885B (fi) 1987-08-31
IE830332L (en) 1983-08-18
FI73885C (fi) 1987-12-10
PH25689A (en) 1991-09-04
DE3381761D1 (de) 1990-08-30
AU554710B2 (en) 1986-08-28
IL80896A0 (en) 1987-03-31
DK479083D0 (da) 1983-10-17
JP2567202B2 (ja) 1996-12-25
ATE54827T1 (de) 1990-08-15
DK479083A (da) 1983-10-17
CA1236774A (en) 1988-05-17
NO162366B (no) 1989-09-11
KR910006889B1 (ko) 1991-09-10
HU195734B (en) 1988-07-28
FI83880C (fi) 1991-09-10
IL80895A0 (en) 1987-03-31
FI864102A0 (fi) 1986-10-10
JPH0769924A (ja) 1995-03-14
NO842962L (no) 1983-10-17
NO172745C (no) 1993-09-01
EP0101506A4 (en) 1984-07-06
ES519875A0 (es) 1984-08-01
FI864102A (fi) 1986-10-10
FI833768A (fi) 1983-10-17
IL80895A (en) 1990-02-09
IE56479B1 (en) 1991-08-14
US4762708A (en) 1988-08-09
IL67930A0 (en) 1983-06-15
NZ220771A (en) 1990-09-26
EP0101506A1 (en) 1984-02-29
IL67930A (en) 1990-02-09
NO833773L (no) 1983-10-17
IL80896A (en) 1990-02-09
AU1339683A (en) 1983-09-08
AR231496A1 (es) 1984-12-28
JP2665332B2 (ja) 1997-10-22
KR840003420A (ko) 1984-09-08
GR77900B (fi) 1984-09-25

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed