DK172422B1 - (5)-substituerede imidazolderivater og fremgangsmåde til fremstilling deraf samt andre 4(5)-substituerede imidazolderivater - Google Patents

(5)-substituerede imidazolderivater og fremgangsmåde til fremstilling deraf samt andre 4(5)-substituerede imidazolderivater Download PDF

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Publication number
DK172422B1
DK172422B1 DK198702082A DK208287A DK172422B1 DK 172422 B1 DK172422 B1 DK 172422B1 DK 198702082 A DK198702082 A DK 198702082A DK 208287 A DK208287 A DK 208287A DK 172422 B1 DK172422 B1 DK 172422B1
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DK
Denmark
Prior art keywords
dihydro
formula
alkyl
lower alkyl
inden
Prior art date
Application number
DK198702082A
Other languages
Danish (da)
English (en)
Other versions
DK208287D0 (da
DK208287A (da
Inventor
Arto Johannes Karjalainen
Arja Leena Karjalainen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI862039A external-priority patent/FI862039A0/fi
Priority claimed from FI870462A external-priority patent/FI870462A0/fi
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of DK208287D0 publication Critical patent/DK208287D0/da
Publication of DK208287A publication Critical patent/DK208287A/da
Application granted granted Critical
Publication of DK172422B1 publication Critical patent/DK172422B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epoxy Resins (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Dental Preparations (AREA)
  • Golf Clubs (AREA)
DK198702082A 1986-05-15 1987-04-24 (5)-substituerede imidazolderivater og fremgangsmåde til fremstilling deraf samt andre 4(5)-substituerede imidazolderivater DK172422B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI862039 1986-05-15
FI862039A FI862039A0 (fi) 1986-05-15 1986-05-15 Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
FI870462 1987-02-04
FI870462A FI870462A0 (fi) 1987-02-04 1987-02-04 Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.

Publications (3)

Publication Number Publication Date
DK208287D0 DK208287D0 (da) 1987-04-24
DK208287A DK208287A (da) 1987-11-16
DK172422B1 true DK172422B1 (da) 1998-06-08

Family

ID=26157963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198702082A DK172422B1 (da) 1986-05-15 1987-04-24 (5)-substituerede imidazolderivater og fremgangsmåde til fremstilling deraf samt andre 4(5)-substituerede imidazolderivater

Country Status (18)

Country Link
US (2) US4933359A (de)
EP (1) EP0247764B1 (de)
JP (1) JP2561272B2 (de)
KR (1) KR950002158B1 (de)
AT (1) ATE66211T1 (de)
AU (1) AU600725B2 (de)
CA (1) CA1299186C (de)
DE (1) DE3772104D1 (de)
DK (1) DK172422B1 (de)
ES (1) ES2037712T3 (de)
FI (1) FI81092C (de)
GR (1) GR3002928T3 (de)
HU (1) HU197314B (de)
IE (1) IE59609B1 (de)
IL (1) IL82541A (de)
NO (1) NO166940C (de)
NZ (1) NZ220306A (de)
PT (1) PT84881B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
FR2669030B1 (fr) * 1990-11-14 1992-12-31 Adir Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
AU3033100A (en) * 1999-01-18 2000-08-01 Boehringer Ingelheim International Gmbh Substituted imidazoles, their preparation and use
US6388090B2 (en) * 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
CZ20023674A3 (cs) * 2000-05-08 2003-09-17 Orion Corporation Nové polycyklické indanylimidazolové sloučeniny s alfa2 adrenergní aktivitou
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
FR2839719B1 (fr) * 2002-05-16 2004-08-06 Pf Medicament Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
US20070060501A1 (en) * 2005-08-30 2007-03-15 Khem Jhamandas Methods and therapies for potentiating a therapeutic action of an opioid receptor agonist and inhibiting and/or reversing tolerance to opioid receptor agonists
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
CN106316812A (zh) * 2009-07-24 2017-01-11 Dpx精细化学奥地利两合公司 作为中间体的二氢化茚衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
US4480118A (en) * 1981-01-13 1984-10-30 Sumitomo Chemical Company, Limited Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same
EP0077122B1 (de) * 1981-09-15 1986-05-07 Imperial Chemical Industries Plc Aminosubstituierte Tetraline und verwandte homocyclische Verbindungen
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
HUT45234A (en) 1988-06-28
FI871655A0 (fi) 1987-04-15
KR880009941A (ko) 1988-10-06
US5026868A (en) 1991-06-25
NZ220306A (en) 1990-02-26
NO872004L (no) 1987-11-16
IE871258L (en) 1987-11-15
NO166940B (no) 1991-06-10
NO166940C (no) 1991-09-25
HU197314B (en) 1989-03-28
EP0247764A1 (de) 1987-12-02
JP2561272B2 (ja) 1996-12-04
DK208287D0 (da) 1987-04-24
IL82541A (en) 1992-06-21
NO872004D0 (no) 1987-05-14
FI871655A (fi) 1987-11-16
EP0247764B1 (de) 1991-08-14
FI81092C (fi) 1990-09-10
AU600725B2 (en) 1990-08-23
AU7310287A (en) 1987-11-19
IL82541A0 (en) 1987-11-30
ATE66211T1 (de) 1991-08-15
IE59609B1 (en) 1994-03-09
FI81092B (fi) 1990-05-31
CA1299186C (en) 1992-04-21
KR950002158B1 (ko) 1995-03-14
US4933359A (en) 1990-06-12
GR3002928T3 (en) 1993-01-25
ES2037712T3 (es) 1993-07-01
DE3772104D1 (de) 1991-09-19
JPS62289566A (ja) 1987-12-16
DK208287A (da) 1987-11-16
PT84881A (en) 1987-06-01
PT84881B (pt) 1990-02-08

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired