FI871655A0 - Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat. - Google Patents

Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.

Info

Publication number
FI871655A0
FI871655A0 FI871655A FI871655A FI871655A0 FI 871655 A0 FI871655 A0 FI 871655A0 FI 871655 A FI871655 A FI 871655A FI 871655 A FI871655 A FI 871655A FI 871655 A0 FI871655 A0 FI 871655A0
Authority
FI
Finland
Prior art keywords
lower alkyl
alkyl
imidazolderivat
substituerade
foerfarande foer
Prior art date
Application number
FI871655A
Other languages
English (en)
Other versions
FI81092B (fi
FI81092C (fi
FI871655A (fi
Inventor
Arja Leena Karjalainen
Arto Johannes Karjalainen
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI862039A external-priority patent/FI862039A0/fi
Priority claimed from FI870462A external-priority patent/FI870462A0/fi
Application filed by Farmos Oy filed Critical Farmos Oy
Priority to FI871655A priority Critical patent/FI81092C/fi
Publication of FI871655A0 publication Critical patent/FI871655A0/fi
Publication of FI871655A publication Critical patent/FI871655A/fi
Publication of FI81092B publication Critical patent/FI81092B/fi
Application granted granted Critical
Publication of FI81092C publication Critical patent/FI81092C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epoxy Resins (AREA)
  • Golf Clubs (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Dental Preparations (AREA)
FI871655A 1986-05-15 1987-04-15 Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat. FI81092C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI871655A FI81092C (fi) 1986-05-15 1987-04-15 Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FI862039A FI862039A0 (fi) 1986-05-15 1986-05-15 Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
FI862039 1986-05-15
FI870462 1987-02-04
FI870462A FI870462A0 (fi) 1987-02-04 1987-02-04 Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
FI871655A FI81092C (fi) 1986-05-15 1987-04-15 Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.
FI871655 1987-04-15

Publications (4)

Publication Number Publication Date
FI871655A0 true FI871655A0 (fi) 1987-04-15
FI871655A FI871655A (fi) 1987-11-16
FI81092B FI81092B (fi) 1990-05-31
FI81092C FI81092C (fi) 1990-09-10

Family

ID=26157963

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871655A FI81092C (fi) 1986-05-15 1987-04-15 Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.

Country Status (18)

Country Link
US (2) US4933359A (fi)
EP (1) EP0247764B1 (fi)
JP (1) JP2561272B2 (fi)
KR (1) KR950002158B1 (fi)
AT (1) ATE66211T1 (fi)
AU (1) AU600725B2 (fi)
CA (1) CA1299186C (fi)
DE (1) DE3772104D1 (fi)
DK (1) DK172422B1 (fi)
ES (1) ES2037712T3 (fi)
FI (1) FI81092C (fi)
GR (1) GR3002928T3 (fi)
HU (1) HU197314B (fi)
IE (1) IE59609B1 (fi)
IL (1) IL82541A (fi)
NO (1) NO166940C (fi)
NZ (1) NZ220306A (fi)
PT (1) PT84881B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
FR2669030B1 (fr) * 1990-11-14 1992-12-31 Adir Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
GB9520150D0 (en) 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
AU3033100A (en) * 1999-01-18 2000-08-01 Boehringer Ingelheim International Gmbh Substituted imidazoles, their preparation and use
US6388090B2 (en) * 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
ATE302757T1 (de) 2000-05-08 2005-09-15 Orion Corp Neue polyzyklische indanylimidazole mit alpha2 adrenergik aktivität
FR2839719B1 (fr) * 2002-05-16 2004-08-06 Pf Medicament Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
CA2627158A1 (en) * 2005-08-30 2007-03-08 Queen's University At Kingston Potentiation of the therapeutic action of an opioid receptor agonist and/or inhibition or reversal of tolerance to an opioid receptoi agonists using an ultralow dose of an alpha-2receptor antagonist
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
WO2011009928A1 (en) * 2009-07-24 2011-01-27 Dsm Pharma Chemicals Regensburg Gmbh Indane derivatives for use as intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
US4480118A (en) * 1981-01-13 1984-10-30 Sumitomo Chemical Company, Limited Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same
ATE19621T1 (de) * 1981-09-15 1986-05-15 Ici Plc Aminosubstituierte tetraline und verwandte homocyclische verbindungen.
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
IE59609B1 (en) 1994-03-09
PT84881A (en) 1987-06-01
NZ220306A (en) 1990-02-26
ES2037712T3 (es) 1993-07-01
KR950002158B1 (ko) 1995-03-14
NO872004L (no) 1987-11-16
DK208287A (da) 1987-11-16
HU197314B (en) 1989-03-28
HUT45234A (en) 1988-06-28
FI81092B (fi) 1990-05-31
NO872004D0 (no) 1987-05-14
ATE66211T1 (de) 1991-08-15
JPS62289566A (ja) 1987-12-16
NO166940B (no) 1991-06-10
IE871258L (en) 1987-11-15
US4933359A (en) 1990-06-12
FI81092C (fi) 1990-09-10
AU7310287A (en) 1987-11-19
US5026868A (en) 1991-06-25
KR880009941A (ko) 1988-10-06
PT84881B (pt) 1990-02-08
EP0247764B1 (en) 1991-08-14
DE3772104D1 (de) 1991-09-19
FI871655A (fi) 1987-11-16
CA1299186C (en) 1992-04-21
NO166940C (no) 1991-09-25
IL82541A (en) 1992-06-21
AU600725B2 (en) 1990-08-23
JP2561272B2 (ja) 1996-12-04
IL82541A0 (en) 1987-11-30
EP0247764A1 (en) 1987-12-02
GR3002928T3 (en) 1993-01-25
DK208287D0 (da) 1987-04-24
DK172422B1 (da) 1998-06-08

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: FARMOS-YHTYMAE OY

MA Patent expired