NO872004L - Fremgangsmaate for fremstilling av terapeutisk aktive 4(5)-substituerte imidazol-derivater. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive 4(5)-substituerte imidazol-derivater.

Info

Publication number
NO872004L
NO872004L NO872004A NO872004A NO872004L NO 872004 L NO872004 L NO 872004L NO 872004 A NO872004 A NO 872004A NO 872004 A NO872004 A NO 872004A NO 872004 L NO872004 L NO 872004L
Authority
NO
Norway
Prior art keywords
lower alkyl
alkyl
preparation
imidazole derivatives
substituted imidazole
Prior art date
Application number
NO872004A
Other languages
English (en)
Other versions
NO872004D0 (no
NO166940B (no
NO166940C (no
Inventor
Arja Leena Karjalainen
Arto Johannes Karjalainen
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI862039A external-priority patent/FI862039A0/fi
Priority claimed from FI870462A external-priority patent/FI870462A0/fi
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of NO872004D0 publication Critical patent/NO872004D0/no
Publication of NO872004L publication Critical patent/NO872004L/no
Priority to NO882728A priority Critical patent/NO167735C/no
Publication of NO166940B publication Critical patent/NO166940B/no
Publication of NO166940C publication Critical patent/NO166940C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Dental Preparations (AREA)
  • Golf Clubs (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Epoxy Resins (AREA)
NO872004A 1986-05-15 1987-05-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4 (5)-substituerte imidazol-derivater, og mellomprodukttil bruk ved fremstillingen. NO166940C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO882728A NO167735C (no) 1986-05-15 1988-06-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4(5)-substituerte imidazol-derivater.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI862039A FI862039A0 (fi) 1986-05-15 1986-05-15 Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
FI870462A FI870462A0 (fi) 1987-02-04 1987-02-04 Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.

Publications (4)

Publication Number Publication Date
NO872004D0 NO872004D0 (no) 1987-05-14
NO872004L true NO872004L (no) 1987-11-16
NO166940B NO166940B (no) 1991-06-10
NO166940C NO166940C (no) 1991-09-25

Family

ID=26157963

Family Applications (1)

Application Number Title Priority Date Filing Date
NO872004A NO166940C (no) 1986-05-15 1987-05-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4 (5)-substituerte imidazol-derivater, og mellomprodukttil bruk ved fremstillingen.

Country Status (18)

Country Link
US (2) US4933359A (no)
EP (1) EP0247764B1 (no)
JP (1) JP2561272B2 (no)
KR (1) KR950002158B1 (no)
AT (1) ATE66211T1 (no)
AU (1) AU600725B2 (no)
CA (1) CA1299186C (no)
DE (1) DE3772104D1 (no)
DK (1) DK172422B1 (no)
ES (1) ES2037712T3 (no)
FI (1) FI81092C (no)
GR (1) GR3002928T3 (no)
HU (1) HU197314B (no)
IE (1) IE59609B1 (no)
IL (1) IL82541A (no)
NO (1) NO166940C (no)
NZ (1) NZ220306A (no)
PT (1) PT84881B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
FR2669030B1 (fr) * 1990-11-14 1992-12-31 Adir Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
EP1147092A1 (en) * 1999-01-18 2001-10-24 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6388090B2 (en) * 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
PE20011321A1 (es) * 2000-05-08 2002-01-03 Orion Corp Indanilimizadoles policiclicos nuevos con actividad adrenergica alfa 2
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
FR2839719B1 (fr) * 2002-05-16 2004-08-06 Pf Medicament Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
AU2006287070A1 (en) * 2005-08-30 2007-03-08 Queen's University At Kingston Potentiation of the therapeutic action of an opioid receptor agonist and/or inhibition or reversal of tolerance to an opioid receptoi agonists using an ultralow dose of an alpha-2 receptor antagonist
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
CN106316812A (zh) * 2009-07-24 2017-01-11 Dpx精细化学奥地利两合公司 作为中间体的二氢化茚衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
US4480118A (en) * 1981-01-13 1984-10-30 Sumitomo Chemical Company, Limited Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same
EP0077122B1 (en) * 1981-09-15 1986-05-07 Imperial Chemical Industries Plc Amino-substituted tetralins and related homocyclic compounds
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
KR950002158B1 (ko) 1995-03-14
FI81092C (fi) 1990-09-10
FI871655A7 (fi) 1987-11-16
IE871258L (en) 1987-11-15
ES2037712T3 (es) 1993-07-01
NZ220306A (en) 1990-02-26
NO872004D0 (no) 1987-05-14
IE59609B1 (en) 1994-03-09
NO166940B (no) 1991-06-10
GR3002928T3 (en) 1993-01-25
IL82541A0 (en) 1987-11-30
DK208287A (da) 1987-11-16
US4933359A (en) 1990-06-12
PT84881B (pt) 1990-02-08
EP0247764B1 (en) 1991-08-14
DK172422B1 (da) 1998-06-08
JP2561272B2 (ja) 1996-12-04
ATE66211T1 (de) 1991-08-15
HU197314B (en) 1989-03-28
DE3772104D1 (de) 1991-09-19
US5026868A (en) 1991-06-25
DK208287D0 (da) 1987-04-24
FI871655A0 (fi) 1987-04-15
CA1299186C (en) 1992-04-21
HUT45234A (en) 1988-06-28
AU600725B2 (en) 1990-08-23
KR880009941A (ko) 1988-10-06
AU7310287A (en) 1987-11-19
NO166940C (no) 1991-09-25
IL82541A (en) 1992-06-21
EP0247764A1 (en) 1987-12-02
JPS62289566A (ja) 1987-12-16
FI81092B (fi) 1990-05-31
PT84881A (en) 1987-06-01

Similar Documents

Publication Publication Date Title
NO872004D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 4(5)-substituerte imidazol-derivater.
ATE162527T1 (de) Piperazinderivate als 5-ht1a antagonisten.
NO177007C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive tetrahydrobenzimidazolderivater
NO870199L (no) Analogifremgangsmaate for fremstilling av nye, terapeutisk virksomme dihydrobenzofuran- og chroman-carboxamidderivater.
ES2112870T3 (es) Derivados de acido glicirretico.
FI942882A7 (fi) Substituoituja imidatsolijohdannaisia ja niiden valmistus ja käyttö
DE69110828D1 (de) Heterozyklische Aminderivate, deren Herstellung und deren Verwendung.
AU2636988A (en) New 2-(piperazinyl)-2-substituted flavonoid derivatives, processes for preparing them and pharmaceutical compositions containing them
ATE90348T1 (de) Pyrido(2,3-d>pyrimidin-derivate.
NO162421C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylinderivater og syreaddisjonssalter derav.
AP9801410A0 (en) Indoline derivatives useful as 5-HT-2C receptor antagonists.
DE3883891D1 (de) Benzimidazol-Derivate und Verfahren zu deren Herstellung.
ES2053580T3 (es) Derivados de pirido(4,3-d)pirimidina.
CA2192596A1 (en) 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
FI914971A0 (fi) 4-(4- eller 6-(trifluormetyl-2 -pyridinyl))-1-piperazinylalkylsubstituerade laktamer.
NO165593C (no) Analogifremgangsmaate ved fremstilling av nye tetracykliske indolderivater.
PT92175A (pt) Processo para a preparacao de 3-amino-sidnoniminas substituidas e de produtos intermediarios farmacologicamente activos
IL79280A (en) 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them