ATE66211T1 - 4(5)-substituierte imidazol-derivate und zwischenverbindungen und verfahren zu ihrer herstellung. - Google Patents
4(5)-substituierte imidazol-derivate und zwischenverbindungen und verfahren zu ihrer herstellung.Info
- Publication number
- ATE66211T1 ATE66211T1 AT87304304T AT87304304T ATE66211T1 AT E66211 T1 ATE66211 T1 AT E66211T1 AT 87304304 T AT87304304 T AT 87304304T AT 87304304 T AT87304304 T AT 87304304T AT E66211 T1 ATE66211 T1 AT E66211T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- alkyl
- processes
- preparation
- imidazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Dental Preparations (AREA)
- Golf Clubs (AREA)
- Epoxy Resins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI862039A FI862039A0 (fi) | 1986-05-15 | 1986-05-15 | Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat. |
FI870462A FI870462A0 (fi) | 1987-02-04 | 1987-02-04 | Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat. |
EP87304304A EP0247764B1 (de) | 1986-05-15 | 1987-05-14 | 4(5)-Substituierte Imidazol-Derivate und Zwischenverbindungen und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE66211T1 true ATE66211T1 (de) | 1991-08-15 |
Family
ID=26157963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87304304T ATE66211T1 (de) | 1986-05-15 | 1987-05-14 | 4(5)-substituierte imidazol-derivate und zwischenverbindungen und verfahren zu ihrer herstellung. |
Country Status (18)
Country | Link |
---|---|
US (2) | US4933359A (de) |
EP (1) | EP0247764B1 (de) |
JP (1) | JP2561272B2 (de) |
KR (1) | KR950002158B1 (de) |
AT (1) | ATE66211T1 (de) |
AU (1) | AU600725B2 (de) |
CA (1) | CA1299186C (de) |
DE (1) | DE3772104D1 (de) |
DK (1) | DK172422B1 (de) |
ES (1) | ES2037712T3 (de) |
FI (1) | FI81092C (de) |
GR (1) | GR3002928T3 (de) |
HU (1) | HU197314B (de) |
IE (1) | IE59609B1 (de) |
IL (1) | IL82541A (de) |
NO (1) | NO166940C (de) |
NZ (1) | NZ220306A (de) |
PT (1) | PT84881B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2225782A (en) * | 1988-12-09 | 1990-06-13 | Farmos Group Limited | Imidazole derivatives useful for treatment of diabetes |
CA1321751C (en) * | 1989-02-21 | 1993-08-31 | Eugene C. Crichlow | Mechanism mediating ruminal stasis in ruminal lactic acidosis |
GB2244431A (en) * | 1990-05-31 | 1991-12-04 | Farmos Oy | Treatment of age related memory impairment and other cognitive disorders |
FR2669030B1 (fr) * | 1990-11-14 | 1992-12-31 | Adir | Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
GB9127050D0 (en) * | 1991-12-20 | 1992-02-19 | Orion Yhtymae Oy | Substituted imidazole derivatives and their preparation and use |
GB9312669D0 (en) | 1993-06-18 | 1993-08-04 | Orion Yhtymae Oy | New opticla isomers |
FR2735776B1 (fr) * | 1995-06-22 | 1997-07-18 | Synthelabo | Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique |
GB9520150D0 (en) * | 1995-10-03 | 1995-12-06 | Orion Yhtymae Oy | New imidazole derivatives |
EP1147092A1 (de) * | 1999-01-18 | 2001-10-24 | Novo Nordisk A/S | Substituierte imidazole, ihre herstellung und verwendung |
US6388090B2 (en) * | 2000-01-14 | 2002-05-14 | Orion Corporation | Imidazole derivatives |
PT1280779E (pt) * | 2000-05-08 | 2005-11-30 | Orion Corp | Novos indanilimidazois policiclicos com actividade adrenergica alfa2 |
FR2839719B1 (fr) * | 2002-05-16 | 2004-08-06 | Pf Medicament | Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments |
US8188126B2 (en) | 2002-05-16 | 2012-05-29 | Pierre Fabre Medicament | Imidazolic compounds and use thereof as alpha-2 adrenergic receptors |
JP2009506080A (ja) * | 2005-08-30 | 2009-02-12 | クィーンズ ユニバーシティー アット キングストン | 超低用量のα−2−受容体アンタゴニストを用いる、オピオイド受容体アゴニストの治療作用の増強方法および/またはオピオイド受容体アゴニストに対する耐性の阻害方法もしくは逆転方法 |
CL2008003553A1 (es) * | 2007-12-05 | 2009-11-27 | Grindeks Jsc | Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso |
EP2456749B1 (de) * | 2009-07-24 | 2016-03-30 | DSM Pharma Chemicals Regensburg GmbH | Indanderivate zur verwendung als zwischenprodukte |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7908922A (nl) * | 1979-12-12 | 1981-07-16 | Akzo Nv | Carboximidamide derivaten. |
US4480118A (en) * | 1981-01-13 | 1984-10-30 | Sumitomo Chemical Company, Limited | Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same |
ATE19621T1 (de) * | 1981-09-15 | 1986-05-15 | Ici Plc | Aminosubstituierte tetraline und verwandte homocyclische verbindungen. |
US4661522A (en) * | 1984-05-24 | 1987-04-28 | Akzo N.V. | Cycloalkane-indene-carboximidamide derivatives |
GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
-
1987
- 1987-04-15 FI FI871655A patent/FI81092C/fi not_active IP Right Cessation
- 1987-04-24 DK DK198702082A patent/DK172422B1/da not_active IP Right Cessation
- 1987-05-14 HU HU872181A patent/HU197314B/hu unknown
- 1987-05-14 US US07/049,882 patent/US4933359A/en not_active Expired - Lifetime
- 1987-05-14 JP JP62118077A patent/JP2561272B2/ja not_active Expired - Lifetime
- 1987-05-14 EP EP87304304A patent/EP0247764B1/de not_active Expired - Lifetime
- 1987-05-14 NZ NZ220306A patent/NZ220306A/xx unknown
- 1987-05-14 ES ES198787304304T patent/ES2037712T3/es not_active Expired - Lifetime
- 1987-05-14 DE DE8787304304T patent/DE3772104D1/de not_active Expired - Lifetime
- 1987-05-14 NO NO872004A patent/NO166940C/no unknown
- 1987-05-14 AT AT87304304T patent/ATE66211T1/de not_active IP Right Cessation
- 1987-05-14 IE IE125887A patent/IE59609B1/en not_active IP Right Cessation
- 1987-05-14 KR KR1019870004746A patent/KR950002158B1/ko not_active IP Right Cessation
- 1987-05-15 CA CA000537323A patent/CA1299186C/en not_active Expired - Lifetime
- 1987-05-15 AU AU73102/87A patent/AU600725B2/en not_active Ceased
- 1987-05-15 IL IL82541A patent/IL82541A/xx not_active IP Right Cessation
- 1987-05-15 PT PT84881A patent/PT84881B/pt unknown
-
1989
- 1989-11-06 US US07/431,959 patent/US5026868A/en not_active Expired - Lifetime
-
1991
- 1991-10-17 GR GR91401554T patent/GR3002928T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3002928T3 (en) | 1993-01-25 |
FI81092B (fi) | 1990-05-31 |
FI81092C (fi) | 1990-09-10 |
AU7310287A (en) | 1987-11-19 |
JP2561272B2 (ja) | 1996-12-04 |
DE3772104D1 (de) | 1991-09-19 |
DK208287D0 (da) | 1987-04-24 |
NZ220306A (en) | 1990-02-26 |
IE59609B1 (en) | 1994-03-09 |
CA1299186C (en) | 1992-04-21 |
FI871655A (fi) | 1987-11-16 |
AU600725B2 (en) | 1990-08-23 |
NO872004L (no) | 1987-11-16 |
US4933359A (en) | 1990-06-12 |
US5026868A (en) | 1991-06-25 |
IL82541A (en) | 1992-06-21 |
PT84881B (pt) | 1990-02-08 |
DK208287A (da) | 1987-11-16 |
EP0247764B1 (de) | 1991-08-14 |
IL82541A0 (en) | 1987-11-30 |
HU197314B (en) | 1989-03-28 |
JPS62289566A (ja) | 1987-12-16 |
NO166940B (no) | 1991-06-10 |
KR950002158B1 (ko) | 1995-03-14 |
ES2037712T3 (es) | 1993-07-01 |
NO166940C (no) | 1991-09-25 |
EP0247764A1 (de) | 1987-12-02 |
PT84881A (en) | 1987-06-01 |
FI871655A0 (fi) | 1987-04-15 |
DK172422B1 (da) | 1998-06-08 |
IE871258L (en) | 1987-11-15 |
HUT45234A (en) | 1988-06-28 |
NO872004D0 (no) | 1987-05-14 |
KR880009941A (ko) | 1988-10-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EELA | Cancelled due to lapse of time |