IL82541A - 4(5)-substituted imidazole derivatives,intermediates thereof,processes for their preparation and pharmaceutical compositions containing them - Google Patents

4(5)-substituted imidazole derivatives,intermediates thereof,processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL82541A
IL82541A IL82541A IL8254187A IL82541A IL 82541 A IL82541 A IL 82541A IL 82541 A IL82541 A IL 82541A IL 8254187 A IL8254187 A IL 8254187A IL 82541 A IL82541 A IL 82541A
Authority
IL
Israel
Prior art keywords
lower alkyl
processes
preparation
alkyl
imidazole derivatives
Prior art date
Application number
IL82541A
Other languages
English (en)
Other versions
IL82541A0 (en
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI862039A external-priority patent/FI862039A0/fi
Priority claimed from FI870462A external-priority patent/FI870462A0/fi
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of IL82541A0 publication Critical patent/IL82541A0/xx
Publication of IL82541A publication Critical patent/IL82541A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epoxy Resins (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Dental Preparations (AREA)
  • Golf Clubs (AREA)
IL82541A 1986-05-15 1987-05-15 4(5)-substituted imidazole derivatives,intermediates thereof,processes for their preparation and pharmaceutical compositions containing them IL82541A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI862039A FI862039A0 (fi) 1986-05-15 1986-05-15 Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
FI870462A FI870462A0 (fi) 1987-02-04 1987-02-04 Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.

Publications (2)

Publication Number Publication Date
IL82541A0 IL82541A0 (en) 1987-11-30
IL82541A true IL82541A (en) 1992-06-21

Family

ID=26157963

Family Applications (1)

Application Number Title Priority Date Filing Date
IL82541A IL82541A (en) 1986-05-15 1987-05-15 4(5)-substituted imidazole derivatives,intermediates thereof,processes for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US4933359A (de)
EP (1) EP0247764B1 (de)
JP (1) JP2561272B2 (de)
KR (1) KR950002158B1 (de)
AT (1) ATE66211T1 (de)
AU (1) AU600725B2 (de)
CA (1) CA1299186C (de)
DE (1) DE3772104D1 (de)
DK (1) DK172422B1 (de)
ES (1) ES2037712T3 (de)
FI (1) FI81092C (de)
GR (1) GR3002928T3 (de)
HU (1) HU197314B (de)
IE (1) IE59609B1 (de)
IL (1) IL82541A (de)
NO (1) NO166940C (de)
NZ (1) NZ220306A (de)
PT (1) PT84881B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
FR2669030B1 (fr) * 1990-11-14 1992-12-31 Adir Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
AU3033100A (en) * 1999-01-18 2000-08-01 Boehringer Ingelheim International Gmbh Substituted imidazoles, their preparation and use
US6388090B2 (en) * 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
PE20011321A1 (es) 2000-05-08 2002-01-03 Orion Corp Indanilimizadoles policiclicos nuevos con actividad adrenergica alfa 2
FR2839719B1 (fr) * 2002-05-16 2004-08-06 Pf Medicament Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
CA2627158A1 (en) * 2005-08-30 2007-03-08 Queen's University At Kingston Potentiation of the therapeutic action of an opioid receptor agonist and/or inhibition or reversal of tolerance to an opioid receptoi agonists using an ultralow dose of an alpha-2receptor antagonist
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
WO2011009928A1 (en) * 2009-07-24 2011-01-27 Dsm Pharma Chemicals Regensburg Gmbh Indane derivatives for use as intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
US4480118A (en) * 1981-01-13 1984-10-30 Sumitomo Chemical Company, Limited Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same
DE3271003D1 (en) * 1981-09-15 1986-06-12 Ici Plc Amino-substituted tetralins and related homocyclic compounds
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
US5026868A (en) 1991-06-25
FI871655A (fi) 1987-11-16
IE59609B1 (en) 1994-03-09
DK208287D0 (da) 1987-04-24
FI81092C (fi) 1990-09-10
IE871258L (en) 1987-11-15
PT84881A (en) 1987-06-01
NO872004D0 (no) 1987-05-14
IL82541A0 (en) 1987-11-30
JPS62289566A (ja) 1987-12-16
HU197314B (en) 1989-03-28
HUT45234A (en) 1988-06-28
NZ220306A (en) 1990-02-26
GR3002928T3 (en) 1993-01-25
FI81092B (fi) 1990-05-31
CA1299186C (en) 1992-04-21
JP2561272B2 (ja) 1996-12-04
DE3772104D1 (de) 1991-09-19
NO166940C (no) 1991-09-25
DK172422B1 (da) 1998-06-08
EP0247764B1 (de) 1991-08-14
EP0247764A1 (de) 1987-12-02
DK208287A (da) 1987-11-16
AU600725B2 (en) 1990-08-23
NO872004L (no) 1987-11-16
AU7310287A (en) 1987-11-19
ES2037712T3 (es) 1993-07-01
NO166940B (no) 1991-06-10
FI871655A0 (fi) 1987-04-15
KR950002158B1 (ko) 1995-03-14
ATE66211T1 (de) 1991-08-15
PT84881B (pt) 1990-02-08
US4933359A (en) 1990-06-12
KR880009941A (ko) 1988-10-06

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Legal Events

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