DK171580B1 - Morpholinderivater, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende dem - Google Patents

Morpholinderivater, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende dem Download PDF

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Publication number
DK171580B1
DK171580B1 DK150088A DK150088A DK171580B1 DK 171580 B1 DK171580 B1 DK 171580B1 DK 150088 A DK150088 A DK 150088A DK 150088 A DK150088 A DK 150088A DK 171580 B1 DK171580 B1 DK 171580B1
Authority
DK
Denmark
Prior art keywords
methoxy
morpholinyl
formula
tetrahydroquinoline
general formula
Prior art date
Application number
DK150088A
Other languages
Danish (da)
English (en)
Other versions
DK150088D0 (da
DK150088A (da
Inventor
Gilbert Regnier
Claude Guillonneau
Jean Lepagnol
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK150088D0 publication Critical patent/DK150088D0/da
Publication of DK150088A publication Critical patent/DK150088A/da
Application granted granted Critical
Publication of DK171580B1 publication Critical patent/DK171580B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Control For Baths (AREA)
  • Earth Drilling (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK150088A 1987-03-24 1988-03-18 Morpholinderivater, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende dem DK171580B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8704047A FR2612926B1 (fr) 1987-03-24 1987-03-24 Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR8704047 1987-03-24

Publications (3)

Publication Number Publication Date
DK150088D0 DK150088D0 (da) 1988-03-18
DK150088A DK150088A (da) 1988-09-25
DK171580B1 true DK171580B1 (da) 1997-02-03

Family

ID=9349348

Family Applications (1)

Application Number Title Priority Date Filing Date
DK150088A DK171580B1 (da) 1987-03-24 1988-03-18 Morpholinderivater, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende dem

Country Status (17)

Country Link
US (1) US4782054A (el)
EP (1) EP0286495B1 (el)
JP (1) JPH0657709B2 (el)
AT (1) ATE89281T1 (el)
AU (1) AU600209B2 (el)
CA (1) CA1313870C (el)
DE (1) DE3880874T2 (el)
DK (1) DK171580B1 (el)
ES (1) ES2006390A6 (el)
FR (1) FR2612926B1 (el)
GR (1) GR1000241B (el)
HK (1) HK57297A (el)
IE (1) IE61882B1 (el)
NZ (1) NZ223984A (el)
OA (1) OA08822A (el)
PT (1) PT87061B (el)
ZA (1) ZA882107B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653999A1 (fr) * 1989-11-06 1991-05-10 Adir Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US6048859A (en) * 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
TW385308B (en) * 1994-03-04 2000-03-21 Merck & Co Inc Prodrugs of morpholine tachykinin receptor antagonists
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
BRPI0510453A (pt) 2004-04-30 2007-10-30 Warner Lambert Co composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138405A (en) * 1966-12-28 1969-01-01 Ici Ltd Morpholine derivatives
BE758766A (fr) * 1969-11-17 1971-05-10 Ici Ltd Nouveaux derives de la morpholine et de la

Also Published As

Publication number Publication date
OA08822A (fr) 1989-03-31
FR2612926B1 (fr) 1989-06-09
US4782054A (en) 1988-11-01
DE3880874T2 (de) 1993-12-23
IE61882B1 (en) 1994-11-30
ATE89281T1 (de) 1993-05-15
AU600209B2 (en) 1990-08-02
DE3880874D1 (de) 1993-06-17
PT87061A (pt) 1988-04-01
IE880851L (en) 1988-09-24
FR2612926A1 (fr) 1988-09-30
GR880100179A (en) 1989-01-31
HK57297A (en) 1997-05-09
ZA882107B (en) 1989-06-28
EP0286495A1 (fr) 1988-10-12
EP0286495B1 (fr) 1993-05-12
CA1313870C (fr) 1993-02-23
AU1352088A (en) 1988-09-22
DK150088D0 (da) 1988-03-18
JPH0657709B2 (ja) 1994-08-03
GR1000241B (el) 1992-05-12
NZ223984A (en) 1990-05-28
PT87061B (pt) 1992-07-31
DK150088A (da) 1988-09-25
ES2006390A6 (es) 1989-04-16
JPS63255279A (ja) 1988-10-21

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