DK171021B1 - Glycerolderivater, fremgangsmåde til deres fremstilling og terapeutiske præparater indeholdende disse - Google Patents

Glycerolderivater, fremgangsmåde til deres fremstilling og terapeutiske præparater indeholdende disse Download PDF

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Publication number
DK171021B1
DK171021B1 DK304090A DK304090A DK171021B1 DK 171021 B1 DK171021 B1 DK 171021B1 DK 304090 A DK304090 A DK 304090A DK 304090 A DK304090 A DK 304090A DK 171021 B1 DK171021 B1 DK 171021B1
Authority
DK
Denmark
Prior art keywords
compound
methyl
methoxy
octadecylamino
tlc
Prior art date
Application number
DK304090A
Other languages
Danish (da)
English (en)
Other versions
DK304090A (da
DK304090D0 (da
Inventor
Pierre Braquet
Colette Broquet
Benedicte Vandamme
Paola Principe-Nicolas
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898929074A external-priority patent/GB8929074D0/en
Priority claimed from GB898929075A external-priority patent/GB8929075D0/en
Application filed by Scras filed Critical Scras
Publication of DK304090D0 publication Critical patent/DK304090D0/da
Publication of DK304090A publication Critical patent/DK304090A/da
Application granted granted Critical
Publication of DK171021B1 publication Critical patent/DK171021B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Hydrogenated Pyridines (AREA)
DK304090A 1989-12-22 1990-12-21 Glycerolderivater, fremgangsmåde til deres fremstilling og terapeutiske præparater indeholdende disse DK171021B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8929074 1989-12-22
GB8929075 1989-12-22
GB898929074A GB8929074D0 (en) 1989-12-22 1989-12-22 Glycerol derivatives
GB898929075A GB8929075D0 (en) 1989-12-22 1989-12-22 Glycerol derivatives

Publications (3)

Publication Number Publication Date
DK304090D0 DK304090D0 (da) 1990-12-21
DK304090A DK304090A (da) 1991-06-23
DK171021B1 true DK171021B1 (da) 1996-04-22

Family

ID=26296423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK304090A DK171021B1 (da) 1989-12-22 1990-12-21 Glycerolderivater, fremgangsmåde til deres fremstilling og terapeutiske præparater indeholdende disse

Country Status (26)

Country Link
US (1) US5116992A (no)
JP (1) JP2648730B2 (no)
KR (1) KR950012533B1 (no)
AR (1) AR247875A1 (no)
AT (1) AT398423B (no)
AU (1) AU635991B2 (no)
BE (1) BE1004091A3 (no)
CA (1) CA2032254C (no)
CH (1) CH681225A5 (no)
DE (1) DE4041449A1 (no)
DK (1) DK171021B1 (no)
ES (1) ES2027550A6 (no)
FI (1) FI906203A (no)
FR (2) FR2656221B1 (no)
GR (1) GR1000688B (no)
HK (1) HK117993A (no)
IE (1) IE65821B1 (no)
IT (1) IT1243413B (no)
LU (1) LU87860A1 (no)
NL (1) NL9002742A (no)
NO (1) NO178698C (no)
NZ (1) NZ236483A (no)
OA (1) OA09336A (no)
PT (1) PT96322B (no)
SE (1) SE501393C2 (no)
TN (1) TNSN90153A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8928580D0 (en) * 1989-12-19 1990-02-21 Scras 3-(n-methyl-n-alkylamino)-methoxymethyl-propanol phosphocholine derivatives
US5206027A (en) * 1990-09-13 1993-04-27 Fuji Photo Film Co., Ltd. Amphipathic compound and liposome comprising the same
AU3216695A (en) * 1994-08-29 1996-03-22 University Of North Carolina At Chapel Hill, The Lipid analogs for treating viral infections
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
US5707978A (en) * 1994-11-22 1998-01-13 Clarion Pharmaceuticals Inc. Heteroaryl-substituted deoxy glycero-phosphoethanolamines
US5665714A (en) * 1995-12-07 1997-09-09 Clarion Pharmaceuticals Inc. N-substituted glycerophosphoethanolamines
US5703062A (en) * 1995-12-07 1997-12-30 Clarion Pharmaceuticals Inc. N-het-substituted glycerophosphoethanolamines
US5730157A (en) * 1995-12-07 1998-03-24 Clarion Pharmaceuticals Inc. Method for treating viral infection
US5827836A (en) * 1996-11-15 1998-10-27 Clarion Pharmaceuticals Inc. Retinoid glycerol phospholipid conjugates
US5891881A (en) * 1997-11-21 1999-04-06 Clarion Pharmaceuticals Inc. Aminoheterocycle-substituted glycerols
US20050187192A1 (en) * 2004-02-20 2005-08-25 Kucera Pharmaceutical Company Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
MXPA06011219A (es) 2004-03-29 2007-05-08 Univ South Florida Tratamiento efectivo de tumores y cancer con triciribina y compuestos relacionados.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2820893C2 (de) * 1978-05-12 1986-02-20 A. Nattermann & Cie GmbH, 5000 Köln Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen
US4562179A (en) * 1982-04-19 1985-12-31 Fujisawa Pharmaceutical Co., Ltd. Phospholipid derivatives, and pharmaceutical composition of the same
DE3323871A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue 1-o-alkyl-3-amino-propan-1,2-diol-2-o-phospholipide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4863941A (en) * 1985-06-18 1989-09-05 Hoffmann-La Roche Inc. Glycerol derivatives

Also Published As

Publication number Publication date
KR910011760A (ko) 1991-08-07
TNSN90153A1 (fr) 1991-03-05
FI906203A (fi) 1991-06-23
JPH0616605A (ja) 1994-01-25
FR2656308B1 (fr) 1994-04-01
ES2027550A6 (es) 1992-06-01
AR247875A1 (es) 1995-04-28
SE9003973L (sv) 1991-06-23
ATA260590A (de) 1994-04-15
AU635991B2 (en) 1993-04-08
NO905377L (no) 1991-06-24
PT96322B (pt) 1998-06-30
NO905377D0 (no) 1990-12-12
LU87860A1 (fr) 1991-05-07
IE904618A1 (en) 1991-07-17
BE1004091A3 (fr) 1992-09-22
AT398423B (de) 1994-12-27
IT1243413B (it) 1994-06-10
PT96322A (pt) 1991-09-30
NO178698B (no) 1996-02-05
FI906203A0 (fi) 1990-12-17
GR1000688B (el) 1992-10-08
JP2648730B2 (ja) 1997-09-03
FR2656308A1 (fr) 1991-06-28
US5116992A (en) 1992-05-26
FR2656221A1 (fr) 1991-06-28
NL9002742A (nl) 1991-07-16
NO178698C (no) 1996-05-15
HK117993A (en) 1993-11-12
FR2656221B1 (fr) 1992-09-18
DK304090A (da) 1991-06-23
IE65821B1 (en) 1995-11-15
DK304090D0 (da) 1990-12-21
KR950012533B1 (ko) 1995-10-18
CA2032254C (en) 1996-12-10
OA09336A (fr) 1992-09-15
AU6837990A (en) 1991-07-11
DE4041449A1 (de) 1991-06-27
IT9022439A1 (it) 1992-06-19
SE501393C2 (sv) 1995-02-06
SE9003973D0 (sv) 1990-12-12
IT9022439A0 (it) 1990-12-19
CA2032254A1 (en) 1991-06-23
NZ236483A (en) 1993-02-25
CH681225A5 (no) 1993-02-15
GR900100847A (en) 1992-05-12

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed