DK170095B1 - Fremgangsmåde til fremstilling af octahydroindolderivater samt mellemprodukter til brug derved - Google Patents

Fremgangsmåde til fremstilling af octahydroindolderivater samt mellemprodukter til brug derved Download PDF

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Publication number
DK170095B1
DK170095B1 DK550587A DK550587A DK170095B1 DK 170095 B1 DK170095 B1 DK 170095B1 DK 550587 A DK550587 A DK 550587A DK 550587 A DK550587 A DK 550587A DK 170095 B1 DK170095 B1 DK 170095B1
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DK
Denmark
Prior art keywords
compound
formula
acid
give
image
Prior art date
Application number
DK550587A
Other languages
Danish (da)
English (en)
Other versions
DK550587D0 (da
DK550587A (da
Inventor
Francis Brion
Jean Buendia
Christian Marie
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK550587D0 publication Critical patent/DK550587D0/da
Publication of DK550587A publication Critical patent/DK550587A/da
Application granted granted Critical
Publication of DK170095B1 publication Critical patent/DK170095B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/08Saturated compounds having a carboxyl group bound to a six-membered ring
    • C07C61/09Completely hydrogenated benzenedicarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Lubricants (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK550587A 1986-10-22 1987-10-21 Fremgangsmåde til fremstilling af octahydroindolderivater samt mellemprodukter til brug derved DK170095B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8614650A FR2605630B1 (fr) 1986-10-22 1986-10-22 Procede de preparation de derives de l'octahydroindole et intermediaires de preparation
FR8614650 1986-10-22

Publications (3)

Publication Number Publication Date
DK550587D0 DK550587D0 (da) 1987-10-21
DK550587A DK550587A (da) 1988-04-23
DK170095B1 true DK170095B1 (da) 1995-05-22

Family

ID=9340061

Family Applications (1)

Application Number Title Priority Date Filing Date
DK550587A DK170095B1 (da) 1986-10-22 1987-10-21 Fremgangsmåde til fremstilling af octahydroindolderivater samt mellemprodukter til brug derved

Country Status (14)

Country Link
US (1) US4879392A (fi)
EP (1) EP0267098B1 (fi)
JP (1) JPH082873B2 (fi)
AT (1) ATE71937T1 (fi)
CA (1) CA1292001C (fi)
DE (1) DE3776273D1 (fi)
DK (1) DK170095B1 (fi)
ES (1) ES2038684T3 (fi)
FI (1) FI84473C (fi)
FR (1) FR2605630B1 (fi)
GR (1) GR3004338T3 (fi)
HU (1) HU198452B (fi)
IE (1) IE60280B1 (fi)
PT (1) PT85964B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900205A1 (de) 1999-01-07 2000-07-13 Basf Ag Verfahren zur Herstellung von (2S,4R,9S)-Octahydro-1H-indol-2-carbonsäure und Zwischenprodukte dafür
AU2003248584A1 (en) * 2002-03-01 2003-09-16 Warner-Lambert Company Llc Method of treating osteoarthritis
JP4884758B2 (ja) * 2005-12-12 2012-02-29 株式会社フジキン エントランス絞り溝付微小流量制御装置の設計方法、
US7570523B2 (en) * 2006-07-31 2009-08-04 Sandisk 3D Llc Method for using two data busses for memory array block selection
AU2010273259B2 (en) * 2009-07-16 2013-03-07 Abbott Laboratories Processes for the synthesis of (2S, 3aR, 7aS)-octahydro-1H-indole carboxylic acid as an intermediate for trandolapril
CN102947461B (zh) * 2010-05-24 2015-01-28 雅培生产操作公司 通过环己烷-1,2-二羧酸二甲酯的催化生物拆分制备(3aS,7aR)-六氢异苯并呋喃-1(3H)-酮
AU2014200205B2 (en) * 2010-05-24 2016-03-31 Bgp Products Operations Gmbh Preparation of (3aS,7aR)-hexahydroisobenzofuran-1(3H)-one by catalyzed biological resolution of dimethyl cyclohexane-1,2-dicarboxylate
CN103360299B (zh) * 2012-04-06 2017-03-01 武汉启瑞药业有限公司 群多普利中间体的异构体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2315661A (en) * 1939-05-27 1943-04-06 Winthrop Chem Co Inc Manufacture of nitrile compounds
DE1695609A1 (de) * 1967-01-12 1972-02-24 Ruetgerswerke Ag Verfahren zur Herstellung von Indolyl-3-acetonitril
US4156016A (en) * 1977-03-03 1979-05-22 Hoffmann-La Roche Inc. Indole compounds and process for their preparation
CA1125783A (en) * 1978-03-27 1982-06-15 Michael E. Condon Thioalkanoylalkanoic acid compounds
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
GR78413B (fi) * 1981-12-29 1984-09-27 Hoechst Ag
US4490386A (en) * 1982-09-23 1984-12-25 Warner-Lambert Company Phosphate salts of 1-[2-[(1-alkoxycarbonyl-3-aralkyl)-amino]-1-oxoalkyl]octahydro-1H-indole-2-carboxylic acids, preparation of, and medical compositions thereof

Also Published As

Publication number Publication date
FR2605630A1 (fr) 1988-04-29
CA1292001C (fr) 1991-11-12
DE3776273D1 (de) 1992-03-05
ES2038684T3 (es) 1993-08-01
GR3004338T3 (fi) 1993-03-31
DK550587D0 (da) 1987-10-21
JPS63104957A (ja) 1988-05-10
FI874639A0 (fi) 1987-10-21
JPH082873B2 (ja) 1996-01-17
IE872652L (en) 1988-04-22
EP0267098A1 (fr) 1988-05-11
FR2605630B1 (fr) 1989-06-30
IE60280B1 (en) 1994-06-29
US4879392A (en) 1989-11-07
EP0267098B1 (fr) 1992-01-22
FI84473C (fi) 1991-12-10
HU198452B (en) 1989-10-30
DK550587A (da) 1988-04-23
PT85964A (fr) 1987-11-01
HUT45494A (en) 1988-07-28
PT85964B (pt) 1990-07-31
ATE71937T1 (de) 1992-02-15
FI874639A (fi) 1988-04-23
FI84473B (fi) 1991-08-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired