DK169721B1 - Substituerede spiro-pyridinderivater, farmaceutiske præparater indeholdende dem og fremgangsmåde til fremstilling af sådanne derivater - Google Patents
Substituerede spiro-pyridinderivater, farmaceutiske præparater indeholdende dem og fremgangsmåde til fremstilling af sådanne derivater Download PDFInfo
- Publication number
- DK169721B1 DK169721B1 DK597184A DK597184A DK169721B1 DK 169721 B1 DK169721 B1 DK 169721B1 DK 597184 A DK597184 A DK 597184A DK 597184 A DK597184 A DK 597184A DK 169721 B1 DK169721 B1 DK 169721B1
- Authority
- DK
- Denmark
- Prior art keywords
- dione
- naphthyridine
- spiro
- compounds
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/561,416 US4652564A (en) | 1983-12-14 | 1983-12-14 | Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents |
| US56141683 | 1983-12-14 | ||
| US64107684 | 1984-08-15 | ||
| US06/641,076 US4632923A (en) | 1984-08-15 | 1984-08-15 | Substituted hetero spiro pyridine derivatives as anti-allergy and anti-inflammatory agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK597184D0 DK597184D0 (da) | 1984-12-13 |
| DK597184A DK597184A (da) | 1985-06-15 |
| DK169721B1 true DK169721B1 (da) | 1995-01-23 |
Family
ID=27072640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK597184A DK169721B1 (da) | 1983-12-14 | 1984-12-13 | Substituerede spiro-pyridinderivater, farmaceutiske præparater indeholdende dem og fremgangsmåde til fremstilling af sådanne derivater |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0144996B1 (de) |
| JP (1) | JPH066586B2 (de) |
| KR (1) | KR900004832B1 (de) |
| AU (1) | AU574749B2 (de) |
| CA (1) | CA1252786A (de) |
| DE (1) | DE3481418D1 (de) |
| DK (1) | DK169721B1 (de) |
| FI (1) | FI79539C (de) |
| GB (1) | GB2153348B (de) |
| GR (1) | GR82463B (de) |
| HK (1) | HK48890A (de) |
| HU (1) | HU193913B (de) |
| IL (1) | IL73823A (de) |
| MY (1) | MY100602A (de) |
| NO (1) | NO163896C (de) |
| NZ (1) | NZ210551A (de) |
| OA (1) | OA07899A (de) |
| PT (1) | PT79672A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3669656D1 (de) * | 1985-06-18 | 1990-04-26 | Schering Corp | Azanaphthalene enthaltende arzneimittelzusammensetzungen. |
| DE3786036T2 (de) * | 1986-04-11 | 1993-09-09 | Schering Corp | Arylsubstituierte naphthyridin- und pyridopyrazin-derivate. |
| US5045542A (en) * | 1986-10-20 | 1991-09-03 | Schering Corporation | Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives |
| CA1309658C (en) * | 1986-12-05 | 1992-11-03 | David J. Blythin | Pharmaceutical compositions for treatment of hyperproliferate skin disease |
| US5350755A (en) * | 1986-12-05 | 1994-09-27 | Schering Corporation | Compounds and methods for treating hyperproliferative skin disease |
| EP1202994B1 (de) | 1999-07-21 | 2004-04-14 | AstraZeneca AB | Verbindungen |
| US7592457B2 (en) * | 2004-10-20 | 2009-09-22 | Korea Research Institute Of Chemical Technology | 3-aryl-3-methyl-quinoline-2, 4-diones, preparation method thereof, and pharmaceutical composition containing the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB855022A (en) * | 1957-08-06 | 1960-11-30 | Geigy Ag J R | Improvements in and relating to carbostyril derivatives |
| JPS5089376A (de) * | 1973-12-19 | 1975-07-17 | ||
| US4215216A (en) * | 1979-04-18 | 1980-07-29 | American Home Products Corporation | 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives |
| EP0092786B1 (de) * | 1982-04-26 | 1987-01-07 | Schering Corporation | 1,8-Naphthyridine- und 1,5,8-Azanaphthyridine-Derivate |
-
1984
- 1984-12-08 DE DE8484114974T patent/DE3481418D1/de not_active Expired - Fee Related
- 1984-12-08 EP EP84114974A patent/EP0144996B1/de not_active Expired - Lifetime
- 1984-12-11 JP JP59261664A patent/JPH066586B2/ja not_active Expired - Lifetime
- 1984-12-13 PT PT79672A patent/PT79672A/pt not_active IP Right Cessation
- 1984-12-13 DK DK597184A patent/DK169721B1/da not_active IP Right Cessation
- 1984-12-13 AU AU36624/84A patent/AU574749B2/en not_active Ceased
- 1984-12-13 GR GR82463A patent/GR82463B/el unknown
- 1984-12-13 CA CA000470037A patent/CA1252786A/en not_active Expired
- 1984-12-13 KR KR1019840007885A patent/KR900004832B1/ko not_active IP Right Cessation
- 1984-12-13 NZ NZ210551A patent/NZ210551A/en unknown
- 1984-12-13 GB GB08431542A patent/GB2153348B/en not_active Expired
- 1984-12-13 FI FI844919A patent/FI79539C/fi not_active IP Right Cessation
- 1984-12-13 HU HU844651A patent/HU193913B/hu not_active IP Right Cessation
- 1984-12-13 NO NO845016A patent/NO163896C/no unknown
- 1984-12-14 IL IL73823A patent/IL73823A/xx not_active IP Right Cessation
- 1984-12-14 OA OA58476A patent/OA07899A/xx unknown
-
1987
- 1987-09-22 MY MYPI87001838A patent/MY100602A/en unknown
-
1990
- 1990-06-21 HK HK488/90A patent/HK48890A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3481418D1 (de) | 1990-04-05 |
| OA07899A (fr) | 1986-11-20 |
| DK597184D0 (da) | 1984-12-13 |
| DK597184A (da) | 1985-06-15 |
| NO163896B (no) | 1990-04-30 |
| NO845016L (no) | 1985-06-17 |
| FI844919A0 (fi) | 1984-12-13 |
| NO163896C (no) | 1990-08-08 |
| FI79539B (fi) | 1989-09-29 |
| JPH066586B2 (ja) | 1994-01-26 |
| KR850004487A (ko) | 1985-07-15 |
| EP0144996B1 (de) | 1990-02-28 |
| EP0144996A3 (en) | 1986-06-11 |
| MY100602A (en) | 1990-12-15 |
| EP0144996A2 (de) | 1985-06-19 |
| PT79672A (en) | 1985-01-01 |
| IL73823A (en) | 1988-03-31 |
| CA1252786A (en) | 1989-04-18 |
| NZ210551A (en) | 1988-05-30 |
| GB8431542D0 (en) | 1985-01-23 |
| FI79539C (fi) | 1990-01-10 |
| GB2153348B (en) | 1987-08-12 |
| HU193913B (en) | 1987-12-28 |
| GB2153348A (en) | 1985-08-21 |
| KR900004832B1 (ko) | 1990-07-07 |
| HUT36477A (en) | 1985-09-30 |
| IL73823A0 (en) | 1985-03-31 |
| GR82463B (en) | 1985-04-16 |
| HK48890A (en) | 1990-06-29 |
| FI844919L (fi) | 1985-06-15 |
| AU3662484A (en) | 1985-06-20 |
| AU574749B2 (en) | 1988-07-14 |
| JPS60156689A (ja) | 1985-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |