OA07899A - Dérivés de spiro pyridine substituée, compositions pharmaceutiques les contenant et procédé de préparation desdits composés et desdites compositions. - Google Patents

Dérivés de spiro pyridine substituée, compositions pharmaceutiques les contenant et procédé de préparation desdits composés et desdites compositions.

Info

Publication number
OA07899A
OA07899A OA58476A OA58476A OA07899A OA 07899 A OA07899 A OA 07899A OA 58476 A OA58476 A OA 58476A OA 58476 A OA58476 A OA 58476A OA 07899 A OA07899 A OA 07899A
Authority
OA
OAPI
Prior art keywords
spiropyridine
derivatives
substituted
compounds
preparation
Prior art date
Application number
OA58476A
Other languages
English (en)
Inventor
David J Blythin
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/561,416 external-priority patent/US4652564A/en
Priority claimed from US06/641,076 external-priority patent/US4632923A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of OA07899A publication Critical patent/OA07899A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
OA58476A 1983-12-14 1984-12-14 Dérivés de spiro pyridine substituée, compositions pharmaceutiques les contenant et procédé de préparation desdits composés et desdites compositions. OA07899A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/561,416 US4652564A (en) 1983-12-14 1983-12-14 Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents
US06/641,076 US4632923A (en) 1984-08-15 1984-08-15 Substituted hetero spiro pyridine derivatives as anti-allergy and anti-inflammatory agents

Publications (1)

Publication Number Publication Date
OA07899A true OA07899A (fr) 1986-11-20

Family

ID=27072640

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58476A OA07899A (fr) 1983-12-14 1984-12-14 Dérivés de spiro pyridine substituée, compositions pharmaceutiques les contenant et procédé de préparation desdits composés et desdites compositions.

Country Status (18)

Country Link
EP (1) EP0144996B1 (fr)
JP (1) JPH066586B2 (fr)
KR (1) KR900004832B1 (fr)
AU (1) AU574749B2 (fr)
CA (1) CA1252786A (fr)
DE (1) DE3481418D1 (fr)
DK (1) DK169721B1 (fr)
FI (1) FI79539C (fr)
GB (1) GB2153348B (fr)
GR (1) GR82463B (fr)
HK (1) HK48890A (fr)
HU (1) HU193913B (fr)
IL (1) IL73823A (fr)
MY (1) MY100602A (fr)
NO (1) NO163896C (fr)
NZ (1) NZ210551A (fr)
OA (1) OA07899A (fr)
PT (1) PT79672A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3669656D1 (de) * 1985-06-18 1990-04-26 Schering Corp Azanaphthalene enthaltende arzneimittelzusammensetzungen.
DE3786036T2 (de) * 1986-04-11 1993-09-09 Schering Corp Arylsubstituierte naphthyridin- und pyridopyrazin-derivate.
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
CA1309658C (fr) * 1986-12-05 1992-11-03 David J. Blythin Compositions pharmaceutiques pour le traitement des maladies hyperproliferatives de la peau
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
EP1202994B1 (fr) 1999-07-21 2004-04-14 AstraZeneca AB Nouveaux composes
US7592457B2 (en) * 2004-10-20 2009-09-22 Korea Research Institute Of Chemical Technology 3-aryl-3-methyl-quinoline-2, 4-diones, preparation method thereof, and pharmaceutical composition containing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB855022A (en) * 1957-08-06 1960-11-30 Geigy Ag J R Improvements in and relating to carbostyril derivatives
JPS5089376A (fr) * 1973-12-19 1975-07-17
US4215216A (en) * 1979-04-18 1980-07-29 American Home Products Corporation 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives
EP0092786B1 (fr) * 1982-04-26 1987-01-07 Schering Corporation Dérivés de la 1,8-naphtyridine et de la 1,5,8-azanaphtyridine

Also Published As

Publication number Publication date
DE3481418D1 (de) 1990-04-05
DK597184D0 (da) 1984-12-13
DK597184A (da) 1985-06-15
NO163896B (no) 1990-04-30
NO845016L (no) 1985-06-17
FI844919A0 (fi) 1984-12-13
NO163896C (no) 1990-08-08
FI79539B (fi) 1989-09-29
JPH066586B2 (ja) 1994-01-26
KR850004487A (ko) 1985-07-15
EP0144996B1 (fr) 1990-02-28
EP0144996A3 (en) 1986-06-11
MY100602A (en) 1990-12-15
EP0144996A2 (fr) 1985-06-19
PT79672A (en) 1985-01-01
IL73823A (en) 1988-03-31
CA1252786A (fr) 1989-04-18
NZ210551A (en) 1988-05-30
GB8431542D0 (en) 1985-01-23
FI79539C (fi) 1990-01-10
GB2153348B (en) 1987-08-12
HU193913B (en) 1987-12-28
GB2153348A (en) 1985-08-21
DK169721B1 (da) 1995-01-23
KR900004832B1 (ko) 1990-07-07
HUT36477A (en) 1985-09-30
IL73823A0 (en) 1985-03-31
GR82463B (en) 1985-04-16
HK48890A (en) 1990-06-29
FI844919L (fi) 1985-06-15
AU3662484A (en) 1985-06-20
AU574749B2 (en) 1988-07-14
JPS60156689A (ja) 1985-08-16

Similar Documents

Publication Publication Date Title
DZ418A1 (fr) Dérivés de céphalosporine, leur procédé de préparation et leur application thérapeutique.
OA07766A (fr) Procédé de préparation de dérivés de cephème.
OA06428A (fr) Composés de 2-penem, procédé de préparation et composition pharmaceutique obtenue.
CY2537B1 (fr) Composés hétérocycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant
OA06533A (fr) Dérivés de la pyrimidine, procédés pour leur préparation, compositions pharmaceutiques contenant ces composés et leur utilisation thérapeutique.
OA06811A (fr) Procédé de préparation de nouveaux dérivés de pyridoxine.
OA06956A (fr) Nouveaux dérivés de la nicotinamide, leur procédé de préparation et composotions herbicides les contenant.
OA08647A (fr) Dérivés d'imidazole, procédés pour leur préparation et composition pharmaceutique les contenant.
OA06914A (fr) Procédé de préparation d'iminodiacides substitués.
OA07003A (fr) Préparation de nouveaux dérivés de la furo-(3,4-c) -pyridine.
OA07699A (fr) Dérivés de la furo-(3,4-c)-pyridine leur préparation et compositions thérapeutiques contenant ces dérivés.
PT80921A (fr) Procede de preparation de derives d'acylaminomethyl-3-imidazo<1,2-a>pyridines et de compositions pharmaceutiques les contenant
FR2445319A1 (fr) Derives de pyridine, procedes pour leur preparation et compositions pharmaceutiques les contenant
OA07864A (fr) Nouveaux dérivés de la vinyl-6 furo-(3,4-c) -pyridine leur préparation et compositions pharmaceutiques à base de ces composés.
OA07602A (fr) Procédé de préparation de composés de céphem, nouveaux produits ainsi obtenus et compositions pharmaceutiques les renfermant.
OA07985A (fr) Nouveaux dérivés céphem, procédé pour la préparation de ces nouveaux composés compositions pharmaceutiques contenant au moins un de ces composés et intermédiaires de synthèse pour leur préparation.
PT76573A (fr) Procede de preparation de derives d'imidazo <1,2-a> pyridine et de compositions pharmaceutiques les contenant
OA07236A (fr) Dérivés de la triazine, procédés pour leur préparation, et compositions pharmaceutiques comportant ces dérivés.
OA09442A (fr) Dérivés de la thiéno-triazolo-diazépine, un procédé pour leur préparation et compositions thérapeutiques en contenant.
OA06951A (fr) Dérivés de la thiéno-pyridinone, leur procédé de préparation et leur application thérapeutique.
OA07390A (fr) Nouveaux dérivés de carbapenem, compositions pharmaceutiques les contenant, composés intermédiaires pour leur préparation, et leurs procédés de production.
OA09209A (fr) "Dérivés de la thiéno-triazolo-diazépine, un procédé de préparation desdits composés et une composition thérapeutique les contenant".
OA07899A (fr) Dérivés de spiro pyridine substituée, compositions pharmaceutiques les contenant et procédé de préparation desdits composés et desdites compositions.
OA09336A (fr) Dérivés du glycérol, un procédé de préparation de ces dérivés et des compositions thérapeutiques les contenant.
PT74651B (fr) Procede de preparation de derives de pyridine et de compositions pharmaceutiques les contenant