DK169565B1 - Fremgangsmåde til detektion af en ondartethed i et legeme, der benytter differentiel binding af potentielt sensitive materialer til lymphocytter - Google Patents

Fremgangsmåde til detektion af en ondartethed i et legeme, der benytter differentiel binding af potentielt sensitive materialer til lymphocytter Download PDF

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Publication number
DK169565B1
DK169565B1 DK413688A DK413688A DK169565B1 DK 169565 B1 DK169565 B1 DK 169565B1 DK 413688 A DK413688 A DK 413688A DK 413688 A DK413688 A DK 413688A DK 169565 B1 DK169565 B1 DK 169565B1
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DK
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Prior art keywords
lymphocytes
intensity
fluorescence
malignancy
pulses
Prior art date
Application number
DK413688A
Other languages
Danish (da)
English (en)
Other versions
DK413688A (da
DK413688D0 (da
Inventor
Boris Cercek
Lea Cercek
Original Assignee
Boris Cercek
Lea Cercek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boris Cercek, Lea Cercek filed Critical Boris Cercek
Publication of DK413688D0 publication Critical patent/DK413688D0/da
Publication of DK413688A publication Critical patent/DK413688A/da
Application granted granted Critical
Publication of DK169565B1 publication Critical patent/DK169565B1/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of Radiation (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
DK413688A 1986-11-24 1988-07-22 Fremgangsmåde til detektion af en ondartethed i et legeme, der benytter differentiel binding af potentielt sensitive materialer til lymphocytter DK169565B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93398286 1986-11-24
US06/933,982 US4835103A (en) 1986-11-24 1986-11-24 Differential binding of membrane potential sensitive materials to lymphocytes
PCT/US1987/003054 WO1988003955A1 (en) 1986-11-24 1987-11-20 Differential binding of potential sensitive materials by lymphocytes
US8703054 1987-11-20

Publications (3)

Publication Number Publication Date
DK413688D0 DK413688D0 (da) 1988-07-22
DK413688A DK413688A (da) 1988-09-21
DK169565B1 true DK169565B1 (da) 1994-11-28

Family

ID=25464748

Family Applications (1)

Application Number Title Priority Date Filing Date
DK413688A DK169565B1 (da) 1986-11-24 1988-07-22 Fremgangsmåde til detektion af en ondartethed i et legeme, der benytter differentiel binding af potentielt sensitive materialer til lymphocytter

Country Status (11)

Country Link
US (1) US4835103A (ja)
EP (1) EP0339028B1 (ja)
JP (1) JPH02501975A (ja)
AT (1) ATE90393T1 (ja)
AU (1) AU611877B2 (ja)
CA (1) CA1312537C (ja)
DE (1) DE3786175T2 (ja)
DK (1) DK169565B1 (ja)
FI (1) FI92076C (ja)
NO (1) NO173409C (ja)
WO (1) WO1988003955A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260186A (en) * 1986-03-10 1993-11-09 Boris Cercek Provision of density specific blood cells for the structuredness of the cytoplasmic matrix (SCM) test
JP2549665B2 (ja) * 1987-07-31 1996-10-30 東亜医用電子株式会社 フロ−サイトメトリ用網状赤血球測定試薬
WO1989008662A1 (en) * 1988-03-11 1989-09-21 Boris Cercek General cancer-associated scm-recognition factor, preparation and method of use
JPH03122553A (ja) * 1989-10-04 1991-05-24 Olympus Optical Co Ltd 光センサー
US5355215A (en) * 1992-09-30 1994-10-11 Environmental Research Institute Of Michigan Method and apparatus for quantitative fluorescence measurements
US6800452B1 (en) * 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
US6944493B2 (en) * 1999-09-10 2005-09-13 Akora, Inc. Indocyanine green (ICG) compositions and related methods of use
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
US7994485B2 (en) * 2008-04-08 2011-08-09 Carestream Health, Inc. Apparatus and method for fluorescence measurements using spatially structured illumination
JP6384821B2 (ja) * 2012-10-26 2018-09-05 国立大学法人三重大学 がん細胞阻害薬、がん幹細胞検出用プローブ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173136A (en) * 1977-11-17 1979-11-06 Schroth Wilhelm Heinrich Method and apparatus for producing multiple groove V-belt pulleys
EP0004061B1 (de) * 1978-03-09 1982-05-19 MERCK PATENT GmbH Verfahren zur Bestimmung leukämischer Zellen
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4424201A (en) * 1978-11-28 1984-01-03 Rockefeller University Employment of a mereyanine dye for the detection of malignant leukocytic cells
US4727020A (en) * 1985-02-25 1988-02-23 Becton, Dickinson And Company Method for analysis of subpopulations of blood cells

Also Published As

Publication number Publication date
AU1041388A (en) 1988-06-16
NO883260D0 (no) 1988-07-22
AU611877B2 (en) 1991-06-27
EP0339028B1 (en) 1993-06-09
FI92076C (fi) 1994-09-26
FI883489A0 (fi) 1988-07-22
FI883489A (fi) 1988-07-22
DK413688A (da) 1988-09-21
JPH02501975A (ja) 1990-07-05
CA1312537C (en) 1993-01-12
WO1988003955A1 (en) 1988-06-02
DK413688D0 (da) 1988-07-22
EP0339028A1 (en) 1989-11-02
ATE90393T1 (de) 1993-06-15
DE3786175T2 (de) 1993-09-23
NO883260L (no) 1988-09-23
FI92076B (fi) 1994-06-15
DE3786175D1 (de) 1993-07-15
NO173409C (no) 1993-12-08
NO173409B (no) 1993-08-30
US4835103A (en) 1989-05-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed