DK168291B1 - N-substituerede diphenylpiperidiner, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelserne samt anvendelse af forbindelserne samt anvendelse af forbindelserne til fremstilling af et lægemiddel til anvendelse til forebyggelse eller behandling af fedme - Google Patents
N-substituerede diphenylpiperidiner, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelserne samt anvendelse af forbindelserne samt anvendelse af forbindelserne til fremstilling af et lægemiddel til anvendelse til forebyggelse eller behandling af fedme Download PDFInfo
- Publication number
- DK168291B1 DK168291B1 DK475286A DK475286A DK168291B1 DK 168291 B1 DK168291 B1 DK 168291B1 DK 475286 A DK475286 A DK 475286A DK 475286 A DK475286 A DK 475286A DK 168291 B1 DK168291 B1 DK 168291B1
- Authority
- DK
- Denmark
- Prior art keywords
- pyridine
- diphenylethenyl
- general formula
- compounds
- piperidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78511385 | 1985-10-07 | ||
| US06/785,113 US4632925A (en) | 1985-10-07 | 1985-10-07 | N-substituted diphenylpiperidines and antiobesity use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK475286D0 DK475286D0 (da) | 1986-10-03 |
| DK475286A DK475286A (da) | 1987-04-08 |
| DK168291B1 true DK168291B1 (da) | 1994-03-07 |
Family
ID=25134481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK475286A DK168291B1 (da) | 1985-10-07 | 1986-10-03 | N-substituerede diphenylpiperidiner, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelserne samt anvendelse af forbindelserne samt anvendelse af forbindelserne til fremstilling af et lægemiddel til anvendelse til forebyggelse eller behandling af fedme |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4632925A (hu) |
| EP (1) | EP0221376B1 (hu) |
| JP (1) | JPH0633254B2 (hu) |
| KR (1) | KR870003984A (hu) |
| AR (1) | AR241422A1 (hu) |
| AT (1) | ATE53997T1 (hu) |
| AU (1) | AU593844B2 (hu) |
| CA (1) | CA1281326C (hu) |
| DE (1) | DE3672134D1 (hu) |
| DK (1) | DK168291B1 (hu) |
| ES (1) | ES2005074A6 (hu) |
| FI (1) | FI85020C (hu) |
| GR (1) | GR862513B (hu) |
| HU (1) | HU196200B (hu) |
| IE (1) | IE59434B1 (hu) |
| IL (1) | IL80232A0 (hu) |
| MC (1) | MC1769A1 (hu) |
| NO (1) | NO166127C (hu) |
| NZ (1) | NZ217798A (hu) |
| PH (1) | PH24167A (hu) |
| PT (1) | PT83495B (hu) |
| SG (1) | SG17593G (hu) |
| ZA (1) | ZA867375B (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN163948B (hu) * | 1986-01-17 | 1988-12-10 | Robins Co Inc A H | |
| GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
| CA2093798C (en) * | 1990-10-10 | 2000-02-01 | John J. Piwinski | Pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof |
| EP0635012B1 (en) * | 1992-03-27 | 1996-07-10 | Schering Corporation | Unbridged bis-aryl carbinol derivatives, compositions and methods of use |
| US5639763A (en) * | 1994-03-01 | 1997-06-17 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
| US6030987A (en) * | 1996-05-17 | 2000-02-29 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines |
| US6017931A (en) * | 1994-03-01 | 2000-01-25 | Fmc Corporation | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
| US6184234B1 (en) * | 1994-03-01 | 2001-02-06 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines |
| EP0844825B1 (en) * | 1995-05-19 | 2002-11-27 | Fmc Corporation | Insecticidal n-(substituted arylmethyl)-4- bis(substituted phenyl or pyridyl)methyl]piperidines |
| US6407116B1 (en) | 1997-09-16 | 2002-06-18 | Takeda Chemical Industries, Inc. | Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs |
| US20100064413A1 (en) * | 2008-03-14 | 2010-03-18 | Simply Weights, LLC | Exercise clothing and accessories |
| ES2507089T3 (es) | 2008-04-29 | 2014-10-14 | F. Hoffmann-La Roche Ag | Derivados del ácido 4-dimetilaminobutírico |
| JP5373888B2 (ja) | 2008-04-29 | 2013-12-18 | エフ．ホフマン−ラ ロシュ アーゲー | Ｃｐｔ２インヒビターとしての４−トリメチルアンモニオ−ブチラート類 |
| EP3737680A1 (en) | 2018-01-08 | 2020-11-18 | F. Hoffmann-La Roche AG | Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors |
| IL299664A (en) * | 2020-09-03 | 2023-03-01 | Hoffmann La Roche | Heterocyclic compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4076717A (en) * | 1971-12-15 | 1978-02-28 | G. D. Searle & Co. | Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid |
| US3931197A (en) * | 1974-02-08 | 1976-01-06 | Richardson-Merrell Inc. | Substituted piperidine derivatives |
| US4650874A (en) * | 1984-11-26 | 1987-03-17 | G. D. Searle & Co. | N-(aralkoxybenzyl)-4(benzhydryl) piperidines |
-
1985
- 1985-10-07 US US06/785,113 patent/US4632925A/en not_active Expired - Fee Related
-
1986
- 1986-09-26 ZA ZA867375A patent/ZA867375B/xx unknown
- 1986-10-03 IL IL80232A patent/IL80232A0/xx not_active IP Right Cessation
- 1986-10-03 DK DK475286A patent/DK168291B1/da active
- 1986-10-03 HU HU864167A patent/HU196200B/hu not_active IP Right Cessation
- 1986-10-03 NZ NZ217798A patent/NZ217798A/xx unknown
- 1986-10-03 AU AU63501/86A patent/AU593844B2/en not_active Ceased
- 1986-10-03 CA CA000519718A patent/CA1281326C/en not_active Expired - Fee Related
- 1986-10-06 DE DE8686113837T patent/DE3672134D1/de not_active Expired - Fee Related
- 1986-10-06 JP JP61236364A patent/JPH0633254B2/ja not_active Expired - Lifetime
- 1986-10-06 NO NO863978A patent/NO166127C/no unknown
- 1986-10-06 ES ES8602424A patent/ES2005074A6/es not_active Expired
- 1986-10-06 AT AT86113837T patent/ATE53997T1/de not_active IP Right Cessation
- 1986-10-06 PT PT83495A patent/PT83495B/pt not_active IP Right Cessation
- 1986-10-06 IE IE263686A patent/IE59434B1/en not_active IP Right Cessation
- 1986-10-06 MC MC861851A patent/MC1769A1/xx unknown
- 1986-10-06 EP EP86113837A patent/EP0221376B1/de not_active Expired - Lifetime
- 1986-10-07 KR KR1019860008388A patent/KR870003984A/ko not_active Application Discontinuation
- 1986-10-07 GR GR862513A patent/GR862513B/el unknown
- 1986-10-07 FI FI864051A patent/FI85020C/fi not_active IP Right Cessation
- 1986-10-07 PH PH34329A patent/PH24167A/en unknown
- 1986-10-23 AR AR86305473A patent/AR241422A1/es active
-
1993
- 1993-02-17 SG SG175/93A patent/SG17593G/en unknown
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